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GABRE Gene

protein-coding GIFtS: 63

GC0XM150873

gamma-aminobutyric acid (GABA) A receptor, epsilon
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc , and/or ⁷Ensembl, ⁸miRBase)
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Aliases
OTTHUMP00000025892 ^²

Descriptions
GABA(A) receptor ^²
GABA(A) receptor subunit epsilon ^³
gamma-aminobutyric acid (GABA) A receptor, epsilon ^²
gamma-aminobutyric acid A receptor, epsilon ^¹

External Ids
HGNC: 4085¹
Entrez Gene: 2564²
UniProtKB: P78334³
Ensembl: ENSG00000102287⁷

Search outside databases for aliases for GABRE gene

Previous GC identifers: GC0XM145456 GC0XM147779 GC0XM148869 GC0XM149739 GC0XM150792

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

EntrezGene summary for GABRE:

The product of this gene belongs to the ligand-gated ionic channel (TC 1.A.9) family. It encodes

the gamma-aminobutyric acid (GABA) A receptor which is a multisubunit chloride channel that

mediates the fastest inhibitory synaptic transmission in the central nervous system. This gene

encodes an epsilon subunit. It is mapped to chromosome Xq28 in a cluster comprised of genes

encoding alpha 3, beta 4 and theta subunits of the same receptor. Alternatively spliced transcript

variants have been identified, but only one is thought to encode a protein. [provided by RefSeq]

UniProtKB/Swiss-Prot: GBRE_HUMAN, P78334

Function: GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal

inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel

Gene Wiki entry for GABRE

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
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Genomic View:

UCSC Golden Path with GeneCards custom track

Transcription factor binding sites upstream to the GABRE gene

Entrez Gene cytogenetic band: Xq28 Ensembl cytogenetic band: Xq28 HGNC cytogenetic band: Xq28

GABRE Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome X GeneLoc Exon Structure

GeneLoc location for GC0XM150873: (about GC identifiers)

Start:	150,872,252 bp from pter
End:	150,893,807 bp from pter
Size:	21,556 bases
Orientation:	minus strand

RefSeq DNA sequence:

NC_000023.9 NT_011726.13

(According to ¹UniProtKB, and/or Ensembl, Phosphorylation sites according to ²Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
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UniProtKB/Swiss-Prot: GBRE_HUMAN, P78334 (See protein sequence)

Recommended Name: Gamma-aminobutyric acid receptor subunit epsilon precursor

Size: 506 amino acids; 57972 Da

Subunit: Generally pentameric. Associates with alpha and beta subunits

Subcellular location: Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane

protein. Cell membrane; Multi-pass membrane protein

Secondary accessions: O15345 O15346 Q99520

REFSEQ proteins (4 alternative transcripts):

NP_004952.2 NP_068819.2 NP_068822.1 NP_068830.1

ENSEMBL proteins:

ENSP00000359353 ENSP00000352321 ENSP00000377491 ENSP00000359350

Human Recombinant Proteins

	Browse Drug Discovery Central at Invitrogen for human recombinant proteins
	Browse Purified and Recombinant Proteins at Millipore
	Browse Human Recombinant Proteins at Sigma-Aldrich
	Browse R&D Systems for human recombinant proteins
	Browse recombinant and purified proteins available from Enzo Life Sciences
	Recombinant Proteins from Abcam (GABA Receptor Epsilon)
	Human Recombinant Proteins from Abnova (GABRE)

Browse Origene for full length recombinant human proteins expressed in human HEK293 cells

5 Gene Ontology (GO) cellular component terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005886	plasma membrane	IEA	--
GO:0005887	integral to plasma membrane	TAS	9039914
GO:0030054	cell junction	IEA	--
GO:0045202	synapse	IEA	--
GO:0045211	postsynaptic membrane	IEA	--

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Antibodies for GABRE:

	Browse Antibodies Central at Invitrogen
	Browse Millipore's Extensive Line of Mono- and Polyclonal Antibodies
	Sigma-Aldrich Antibodies for GABRE
	Browse R&D Systems for Antibodies
	Antibodies from Abcam (GABA Receptor Epsilon), each with their Abpromise^SM
	Browse Abnova for Monoclonal and Polyclonal Antibodies
	Search Novus for antibodies for GABRE

Assays for GABRE:

	Browse Invitrogen for biochemical assays
	Browse Kits and Assays available from Millipore
	Browse R&D Systems for biochemical assays
	Browse biochemical assays available from Enzo Life Sciences

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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Graphical View of Domain Structure for InterPro Entry P78334

ProtoNet protein and cluster: P78334

3 Blocks protein families:

IPB006028 Gamma-aminobutyric acid A (GABAA) receptor signature

IPB006201 Neurotransmitter-gated ion-channel

IPB008099 Gamma-aminobutyric-acid A receptor epsilon subunit signature

UniProtKB/Swiss-Prot: GBRE_HUMAN, P78334

Similarity: Belongs to the ligand-gated ionic channel (TC 1.A.9) family

(According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (GABRE)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (GABRE)

OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 4): NM_021984

Applied Biosystems Silencer® siRNAs for GABRE

Sigma-Aldrich siRNA and siRNA Panels for GABRE

Sigma-Aldrich shRNA for GABRE

Explore Sigma-Aldrich super-pooled esiRNAs

Clones:		Invitrogen Clones for GABRE
		Browse Clones for the Expression of Recombinant Proteins Available from Millipore

OriGene GFP tagged cDNA clones in CMV expression vector (see all 4): NM_004961
Myc/DDK tagged cDNA clones in CMV expression vector (see all 4): NM_004961
untagged cDNA clones in CMV expression vector (see all 5): NM_004961

Primers:

Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers

OriGene genome-wide validated SYBR primer pairs: NM_004961

UniProtKB/Swiss-Prot: GBRE_HUMAN, P78334

Function: GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal

inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel

Genatlas biochemistry entry for GABRE:

gamma-aminobutyric acid (GABA) A receptor,ionotropic,epsilon,predominantly expressed in adult

brain,subunit,component of a pentameric receptor mediating inhibitory neurotransmission,clustered

with GABRA3 and GABRB4

5/6 Gene Ontology (GO) molecular function terms (links to tree view) (see all 6 ):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0004890	GABA-A receptor activity	TAS	9039914
GO:0005216	ion channel activity	IEA	--
GO:0005230	extracellular ligand-gated ion channel activity	IEA	--
GO:0005254	chloride channel activity	IEA	--
GO:0030594	neurotransmitter receptor activity	IEA	--

About this table

(Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to ¹UniProtKB, ²MINT, and/or ³STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
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1 Sigma-Aldrich "Your Favorite Gene" Pathway for GABRE (Your Favorite Gene powered by Ingenuity)

GABA Receptor Signaling

GeneDecks GABRE for the pathways selected above

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5/18 Interacting proteins for GABRE (ENSP00000359353³) via UniProtKB, MINT, and/or STRING (see all 18 )

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
GABRQ	ENSP00000276369³	STRING (score=.826)
GABRA2	ENSP00000348897³	STRING (score=.82)
GABRA3	ENSP00000359337³	STRING (score=.82)
GABRA4	ENSP00000264318³	STRING (score=.816)
GABRB3	ENSP00000372479³	STRING (score=.815)

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2 Gene Ontology (GO) biological process terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0006811	ion transport	IEA	--
GO:0007214	gamma-aminobutyric acid signaling pathway	TAS	9039914

About this table

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
About This Section

Enzo Life Sciences drugs & compounds for GABRE

Browse Small Molecules at Sigma-Aldrich

Compounds for GABRE available from Tocris Bioscience

Compound	Action	CAS number
Muscimol	Potent GABAA agonist	[2763-96-4]
(+)-Bicuculline	Potent GABAA antagonist	[485-49-4]
Indiplon	Subtype-selective GABAA receptor positive allosteric modulator	[325715-02-4]
L-655,708	Selective for alpha5-containing GABAA receptors	[130477-52-0]
SR 95531 hydrobromide	Selective, competitive GABAA receptor antagonist	[104104-50-9]

About this table

(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Invitrogen, Millipore, and/or Abnova,
siRNAs from Applied Biosystems, Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene,
Tagged/untagged cDNA clones from OriGene)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (GABRE)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (GABRE)

OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 4): NM_021984

Sigma-Aldrich siRNA and siRNA Panels for GABRE

Sigma-Aldrich shRNA for GABRE

Explore Sigma-Aldrich super-pooled esiRNAs

Applied Biosystems Silencer® siRNAs:

NM_004961

REFSEQ mRNAs for GABRE gene (4 alternative transcripts):

NM_004961.3 NM_021984.2 NM_021987.2 NM_021990.2

NM_004961

               OriGene GFP tagged cDNA clones in CMV expression vector (see all 4): NM_004961
                                 Myc/DDK tagged cDNA clones in CMV expression vector (see all 4): NM_004961
                                 untagged cDNA clones in CMV expression vector (see all 5): NM_004961

Additional cDNA sequence:

AF086385.1 AK299174.1 AK303072.1 BC026337.1 BC047108.1 BC059376.1 CR591394.1 U66661.1

Y07637.1 Y09765.1

11 DOTS entries:

DT.443863 DT.95350380 DT.91825239 DT.100816070 DT.91755826 DT.97833425 DT.115945 DT.95107482

DT.91750087 DT.91755827 DT.121289670

24/125 AceView cDNA sequences (see all 125 ):

U66661 AA954089 AI682740 BX478724 AA347289 Y09765 NM_021984 CR591394

BU732085 AI432632 AA855126 AI963395 U92285 CD671953 CA310783 NM_021987

BM678523 AI400573 AI334197 BQ016181 AI824213 C00867 CD369824 AI279924

highest scoring ESTs for GABRE:

Y09765 AL603607 BG714934 BG716264 BI667764 CN481624 CN484232 AA299532 AA321214 AA347289

Unigene Cluster for GABRE:

Gamma-aminobutyric acid (GABA) A receptor, epsilon

Hs.22785 [show with all ESTs]

Unigene Representative Sequence: BC026337

GeneLoc Exon Structure

5/10 Alternative Splicing Database (ASD) splice patterns (SP) for GABRE (see all 10 )

ExUns:	1a	·	1b	·	1c	^	2a	·	2b	^	3a	·	3b	·	3c	·	3d	^	4	^	5	^	6	^	7	^	8	^	9a	·	9b	^	10	^	11	^	12a	·	12b	^	13a	·	13b	·	13c	^	14a	·	14b
SP1:							-		-		-				-		-												-		-		-		-										-
SP2:							-				-				-		-
SP3:																									-				-
SP4:																																													-
SP5:																																			-

About this scheme

ECgene alternative splicing isoforms for GABRE

4 Ensembl transcripts including schematic representations:

ENST00000370328 ENST00000359363 ENST00000393914 ENST00000370325

(Experimental results according to ¹GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to ²GeneAnnot , ³GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Expression Assays from Applied Biosystems )
About This Section

GABRE expression in normal and diseased human tissues

Applied Biosystems TaqMan ® Gene Expression Assays for GABRE

¹ / ² / ³

3 probe-sets matching GABRE gene

Affymetrix probe-set	Array	# genes	Sensitivity	Specificity	Correlation	Length	Gb_Accession	Consensus	Uniqueness	Score	Rank
Affymetrix probe-set	Array	GeneAnnot data			GeneNote data		GeneTide data
34280_at²^{, 3}	U95-A	1	1.00	1.00	1.00	1.00	Y09765	1.00	0.87	0.94	1
204537_s_at²^{, 3}	U133-A	1	1.00	1.00	--	--	NM_004961	0.60	1.00	0.82	1
204537_s_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--

GeneDecks GABRE for binary patterns associated with the probe-sets selected above

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Data from

(Publications) and GNF BioGPS
About these images
About these images

CGAP SAGE TAG: CCCCAATGCT

SOURCE GeneReport for Unigene cluster: Hs.22785
Expression variation in blood from EXPOLDB for GABRE
UniProtKB/Swiss-Prot: GBRE_HUMAN, P78334
Tissue specificity: Expressed in many tissues. Highest levels of expression in adult heart and
placenta

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD and/or ⁵MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
About This Section

Orthologs for GABRE gene from 5/6 species (see all 6 )

Organism	Gene	Locus	Description	Human Similarity	NCBI accessions
dog (Canis familiaris)	GABRE¹	--	gamma-aminobutyric acid (GABA) A receptor, epsilon	85.32(n) 79.25(a)	492220 XM_549340.2 XP_549340.2
chimpanzee (Pan troglodytes)	GABRE¹	--	gamma-aminobutyric acid (GABA) A receptor, epsilon	99.49(n) 99.49(a)	465911 XM_521310.2 XP_521310.2
cow (Bos taurus)	GABRE¹	--	gamma-aminobutyric acid (GABA) A receptor, epsilon	81.56(n) 73.77(a)	524115 XM_602435.3 XP_602435.2
rat (Rattus norvegicus)	Gabre¹	--	gamma-aminobutyric acid (GABA) A receptor, epsilon	78.5(n) 73.2(a)	65191 NM_023091.1 NP_075579.1
mouse (Mus musculus)	Gabre^{1, 5}	X⁵	gamma-aminobutyric acid (GABA) A receptor, subunit more⁵ gamma-aminobutyric acid (GABA-A) receptor, subunit more¹	77.97(n)¹ 72.03(a)¹	14404¹ NM_017369.2¹ NP_059065.2¹ AF090376⁵ AF189263⁵ (see all 12)

About this table Species with no ortholog for GABRE

ENSEMBL Gene Tree for GABRE

(Paralogs according to ¹HomoloGene
and ²Ensembl, Pseudogenes according to ³Pseudogene.org)
About This Section

Paralogs for GABRE gene

GABRG2² GABRG1² GABRG3²

(According to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
About This Section

10/151 NCBI SNPs in GABRE are shown (see all 151 )
(Click for Applied Biosystems TaqMan ® Genotyping Assay) (see all 91)

AB	SNP ID	Valid	Chr X pos	Sequence	Recs	AA Chg	Type	More	Recs	Allele freq	Pop	Total sample	More
AB	Genomic Data				Transcription Data				Allele Frequencies
				--	--	--		--	--				--
	rs1061421^1,2	C,F,H,O	150873252(-)	`TGCAGA/TTAGAT`	4	--	ut3¹ ese³		9		EU EA WA NA	742
	rs1061418^1,2	C,F,H	150873636(-)	`TGAGTT/CTTCTC`	4	--	ut3¹ ese³		8		MN EU EA WA NA	746
	rs5970170^1,2	C,F,H	150872904(+)	`GCGAGT/CAATGC`	4	--	ut3¹ ese³		11		EU EA WA NA	764
	rs1061420^1,2	C,F,H	150873428(-)	`CTTTGT/CAGTGC`	4	--	ut3¹		7		EU EA WA NA	552
	rs1139916^1,2	C,F,H	150888835(-)	`AGATCG/TCCGTC`	4	S/A	mis¹ ut5¹		8		EU EA WA	547
--	rs7054391^1,2	F,H	150872102(+)	`TTCCTT/CACTAA`	4	--	ng5¹		4		EU EA WA	382
--	rs1061417^1,2	C,H	150873846(-)	`GGCTTG/TTTTGC`	4	V/F	mis¹		5		MN EU EA WA	604
	rs7882031^1,2	H	150873147(+)	`CAGCAA/TGGAGA`	4	--	ut3¹ ese³ trp³		4		EU EA WA	414
	rs7060135^1,2	A	150873657(+)	`CAGGTA/CGGGGA`	4	--	ut3¹ ese³ trp³		0	--	--	--	--
	rs2856386^1,2	H	150879016(+)	`AAATCA/CAACTG`	4	F/L	mis¹		4		EU EA WA	402

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HapMap Linkage Disequilibrium images for GABRE (up to first 250kb)

(in which this Gene is Involved, According to OMIM, UniProtKB, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
About This Section

OMIM: 300093

Human Genome Epidemiology Navigator: GABRE (4 documents)

(Possibly Related Articles in Doctor's Guide)
About This Section

(in PubMed. Associations of this gene to articles via ¹Novoseek, ²HGNC, ³Entrez Gene, ⁴UniProtKB/Swiss-Prot, ⁵UniProtKB/TrEMBL, ⁶GAD, and/or ⁷PharmGKB)
About This Section

10/20 PubMed articles for GABRE gene (see all 20 ):

Insensitivity to anaesthetic agents conferred by a class of GABA(A) receptor subunit. (PubMed id 9039914)^{2, 3, 4} Davies P.A.... Kirkness E.F. (1997)
An mRNA encoding a putative GABA-gated chloride channel is expressed in the human cardiac conduction system. (PubMed id 9084408)^{2, 3, 4} Garret M....Margolskee R.F. (1997)
A gene in human chromosome band Xq28 (GABRE) defines a putative new subunit class of the GABAA neurotransmitter receptor. (PubMed id 9339354)^{3, 4} Wilke K.... Poustka A. (1997)
Investigation of gamma-aminobutyric acid (GABA) A receptors genes and migraine susceptibility. (PubMed id 19087248)^{1, 3} Fernandez F....Griffiths L.R. (2008)
Strong genetic evidence for a selective influence of GABA(A) receptors on a component of the bipolar disorder phenotype. (PubMed id 19078961)³ Craddock N....O'Donovan M.C. (2008)
Intracortical hyperexcitability in humans with a GABAA receptor mutation. (PubMed id 17615250)³ Fedi M....Reutens D.C. (2008)
Identification of new putative susceptibility genes for several psychiatric disorders by association analysis of regulatory and non-synonymous SNPs of 306 genes involved in neurotransmission and neurodevelopment. (PubMed id 19086053)³ GratacA^s M....Carracedo A. (2008)
Trafficking and potential assembly patterns of epsilon-containing GABAA receptors. (PubMed id 17714454)³ Jones B.L. and Henderson L.P. (2007)
Channel opening by anesthetics and GABA induces similar changes in the GABAA receptor M2 segment. (PubMed id 17293408)³ Rosen A....Akabas M.H. (2007)
Heterogeneous GABAA receptor subunit expression in pediatric epilepsy patients. (PubMed id 15755675)³ Porter B.E....Brooks-Kayal A.R. (2005)

(in PubMed, OMIM, and NCBI Bookshelf)
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		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
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Entrez Gene: 2564	HGNC: 4085	AceView: GABRE	Ensembl:ENSG00000102287	euGenes: HUgn2564
ECgene: GABRE	H-InvDB: GABRE

(According to HUGE)
About This Section

(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
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Licensable Technologies for GABRE
(Available from WIS Yeda, Salk, Tufts)

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(Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
Enzo Life Sciences, and/or Tocris Bioscience)
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Products for GABRE:

TaqMan ® Gene Expression Assays

TaqMan ® Genotyping Assays

Free SNP selection tool

Invitrogen iPath Pathways	Invitrogen BLOCK-iT™ RNAi
Invitrogen Antibodies	Invitrogen Assays
Invitrogen Clones	Invitrogen Q-PCR Products
Invitrogen Human Recombinant Kinases	Invitrogen Custom Antibody and Peptide Service
Invitrogen Proteins / Assays / Screening Services	Search Invitrogen catalog for GABRE-related products

	Millipore Custom Antibody & Bulk Services
	Millipore Preclinical / Clinical Development Services
	Millipore Immunoassay Services
	Millipore Target Screening & Profiling Services

	Predesigned and custom siRNAs for GABRE		Antibodies for GABRE
	Explore super-pooled esiRNAs		Browse proteins at Sigma-Aldrich
	Lentivirus-delivered shRNAs for GABRE		Browse small molecules at Sigma-Aldrich
	"Your Favorite Gene" Pathways		feedback

	Antibodies		Primer Pairs
	Cell Culture Products		ELISAs
	Flow Cytometry Kits		Protease Activity Assays & Reagents
	Cell Selection/Detection Kits & Reagents		ELISA/Assay Development Kits & Reagents
	Multiplex/Array Assay Kits & Reagents		ELISpot Kits & Development Modules
	Recombinant & Natural Proteins

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Tocris compounds for GABRE

	Drugs for GABRE
	Search www.enzolifesicences.com for proteins, assays, substrates, inhibitors & antibodies

Search Novus for antibodies for GABRE

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GABRE Gene

protein-coding GIFtS: 63

Aliases &
Descriptions
for GABRE

Summaries
for GABRE

Genomic Location
for GABRE

Proteins
for GABRE

Protein Domains/
Families
for GABRE

Gene Function
for GABRE

Pathways & Interactions
for GABRE

Drugs & Compounds
for GABRE

Transcripts
for GABRE

Expression
for GABRE

Orthologs
for GABRE

Paralogs
for GABRE

SNPs/Variants
for GABRE

Disorders & Mutations
for GABRE

Medical News
for GABRE

Publications
for GABRE

Search for GABRE

Genome Databases showing GABRE

Other Databases showing GABRE

Specialized Databases showing GABRE

Licensable Technologies
for GABRE

Services
for GABRE

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

GABRE Gene

protein-coding GIFtS: 63

Aliases & Descriptionsfor GABRE

Summariesfor GABRE

Genomic Locationfor GABRE

Proteinsfor GABRE

Protein Domains/Familiesfor GABRE

Gene Functionfor GABRE

Pathways & Interactionsfor GABRE

Drugs & Compoundsfor GABRE

Transcriptsfor GABRE

Expression for GABRE

Orthologsfor GABRE

Paralogsfor GABRE

SNPs/Variantsfor GABRE

Disorders & Mutationsfor GABRE

Medical Newsfor GABRE

Publicationsfor GABRE

Search for GABRE

Genome Databases showing GABRE

Other Databases showing GABRE

Specialized Databases showing GABRE

Licensable Technologiesfor GABRE

Servicesfor GABRE

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Aliases &
Descriptions
for GABRE

Summaries
for GABRE

Genomic Location
for GABRE

Proteins
for GABRE

Protein Domains/
Families
for GABRE

Gene Function
for GABRE

Pathways & Interactions
for GABRE

Drugs & Compounds
for GABRE

Transcripts
for GABRE

Expression
for GABRE

Orthologs
for GABRE

Paralogs
for GABRE

SNPs/Variants
for GABRE

Disorders & Mutations
for GABRE

Medical News
for GABRE

Publications
for GABRE

Licensable Technologies
for GABRE

Services
for GABRE