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GABRD Gene

protein-coding GIFtS: 68

GC01P001913

gamma-aminobutyric acid (GABA) A receptor, delta
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc , and/or ⁷Ensembl, ⁸miRBase)
About This Section

Aliases
MGC45284 ^²
OTTHUMP00000038578 ^²

Descriptions
GABA(A) receptor subunit delta ^², ³
GABA-A receptor, delta polypeptide ^²
gamma-aminobutyric acid (GABA) A receptor, delta ^²
gamma-aminobutyric acid A receptor, delta ^¹

External Ids
HGNC: 4084¹
Entrez Gene: 2563²
UniProtKB: O14764³
Ensembl: ENSG00000187730⁷

Search outside databases for aliases for GABRD gene

Previous GC identifers: GC01P001512 GC01P9L0120 GC00M9Y0062

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

EntrezGene summary for GABRD:

Gamma-aminobutyric acid (GABA) is the major inhibitory neurotransmitter in the mammalian brain

where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance

of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A

receptor. The GABA-A receptor is generally pentameric and there are five types of subunits: alpha,

beta, gamma, delta, and rho. This gene encodes the delta subunit. Mutations in this gene have been

associated with susceptibility to generalized epilepsy with febrile seizures, type 5.

Alternatively spliced transcript variants have been described for this gene, but their biological

validity has not been determined. [provided by RefSeq]

UniProtKB/Swiss-Prot: GBRD_HUMAN, O14764

Function: GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal

inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel

Gene Wiki entry for GABRD

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
About This Section

Genomic View:

UCSC Golden Path with GeneCards custom track

Transcription factor binding sites upstream to the GABRD gene

Entrez Gene cytogenetic band: 1p|1p36.3 Ensembl cytogenetic band: 1p36.33 HGNC cytogenetic band: 1p36.3

GABRD Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 1 GeneLoc Exon Structure

GeneLoc location for GC01P001913: (about GC identifiers)

Start:	1,940,703 bp from pter
End:	1,952,050 bp from pter
Size:	11,348 bases
Orientation:	plus strand

RefSeq DNA sequence:

NC_000001.9 NT_004350.18

(According to ¹UniProtKB, and/or Ensembl, Phosphorylation sites according to ²Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
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UniProtKB/Swiss-Prot: GBRD_HUMAN, O14764 (See protein sequence)

Recommended Name: Gamma-aminobutyric acid receptor subunit delta precursor

Size: 452 amino acids; 50708 Da

Subunit: Generally pentameric. There are five types of GABA(A) receptor chains: alpha, beta, gamma,

delta, and rho

Subcellular location: Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane

protein. Cell membrane; Multi-pass membrane protein

Secondary accessions: Q8N4N9

REFSEQ proteins: NP_000806.2

ENSEMBL proteins:

ENSP00000367848

Human Recombinant Proteins

	Browse Drug Discovery Central at Invitrogen for human recombinant proteins
	Millipore Purified and/or Recombinant GABRD Protein
	Browse Human Recombinant Proteins at Sigma-Aldrich
	Browse R&D Systems for human recombinant proteins
	Browse recombinant and purified proteins available from Enzo Life Sciences
	Recombinant Proteins from Abcam (GABA A Receptor delta)
	Browse Abnova for Human Recombinant Proteins

Browse Origene for full length recombinant human proteins expressed in human HEK293 cells

5 Gene Ontology (GO) cellular component terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005886	plasma membrane	IEA	--
GO:0005887	integral to plasma membrane	TAS	2176788
GO:0030054	cell junction	IEA	--
GO:0045202	synapse	IEA	--
GO:0045211	postsynaptic membrane	IEA	--

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Antibodies for GABRD:

	Invitrogen Antibodies for GABRD
	Millipore Mono- and Polyclonal Antibodies for the study of GABRD
	Sigma-Aldrich Antibodies for GABRD
	R&D Systems Antibodies for GABRD (GABA-A-R delta)
	Antibodies from Abcam (GABA A Receptor delta), each with their Abpromise^SM
	Browse Abnova for Monoclonal and Polyclonal Antibodies
	Search Novus for antibodies for GABRD

Assays for GABRD:

	Browse Invitrogen for biochemical assays
	Browse Kits and Assays available from Millipore
	Browse R&D Systems for biochemical assays
	Browse biochemical assays available from Enzo Life Sciences

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

Graphical View of Domain Structure for InterPro Entry O14764

ProtoNet protein and cluster: O14764

3 Blocks protein families:

IPB006028 Gamma-aminobutyric acid A (GABAA) receptor signature

IPB006201 Neurotransmitter-gated ion-channel

IPB008098 Gamma-aminobutyric-acid A receptor delta subunit signature

UniProtKB/Swiss-Prot: GBRD_HUMAN, O14764

Similarity: Belongs to the ligand-gated ionic channel (TC 1.A.9) family

(According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (GABRD)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (GABRD)

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_000815

Applied Biosystems Silencer® siRNAs for GABRD

Sigma-Aldrich siRNA and siRNA Panels for GABRD

Sigma-Aldrich shRNA for GABRD

Explore Sigma-Aldrich super-pooled esiRNAs

Clones:		Invitrogen Clones for GABRD
		Browse Clones for the Expression of Recombinant Proteins Available from Millipore

OriGene GFP tagged cDNA clone in CMV expression vector: NM_000815
Myc/DDK tagged cDNA clone in CMV expression vector: NM_000815
untagged cDNA clone in CMV expression vector: NM_000815

Primers:

Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers

OriGene genome-wide validated SYBR primer pairs: NM_000815

UniProtKB/Swiss-Prot: GBRD_HUMAN, O14764

Function: GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal

inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel

Genatlas biochemistry entry for GABRD:

gamma-aminobutyric acid (GABA) A receptor,ionotropic,delta,subunit,component of a pentameric

receptor mediating inhibitory neurotransmission

6 MGI mutant phenotypes (inferred from 1 allele) (MGI details for Gabrd):

behavior/neurological	hearing/vestibular/ear	homeostasis/metabolism	lethality-postnatal	nervous system
reproductive system

5/6 Gene Ontology (GO) molecular function terms (links to tree view) (see all 6 ):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0004890	GABA-A receptor activity	TAS	2176788
GO:0005216	ion channel activity	IEA	--
GO:0005230	extracellular ligand-gated ion channel activity	IEA	--
GO:0005254	chloride channel activity	IEA	--
GO:0030594	neurotransmitter receptor activity	IEA	--

About this table

(Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to ¹UniProtKB, ²MINT, and/or ³STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

1 Sigma-Aldrich "Your Favorite Gene" Pathway for GABRD (Your Favorite Gene powered by Ingenuity)

GABA Receptor Signaling

GeneDecks GABRD for the pathways selected above

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5/26 Interacting proteins for GABRD (ENSP00000367848³ O14764²) via UniProtKB, MINT, and/or STRING (see all 26 )

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
UBQLN1	Q9UMX0²	MINT-66488
UBQLN4	Q9NRR5²	MINT-2859100
MAX	ENSP00000284165³	STRING (score=.899)
TERT	ENSP00000309572³	STRING (score=.899)
GABRA1	ENSP00000023897³	STRING (score=.825)

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3 Gene Ontology (GO) biological process terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0006811	ion transport	IEA	--
GO:0007165	signal transduction	TAS	2176788
GO:0007268	synaptic transmission	IEA	--

About this table

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
About This Section

Enzo Life Sciences drugs & compounds for GABRD

Browse Small Molecules at Sigma-Aldrich

Compounds for GABRD available from Tocris Bioscience

Compound	Action	CAS number
Muscimol	Potent GABAA agonist	[2763-96-4]
(+)-Bicuculline	Potent GABAA antagonist	[485-49-4]
Indiplon	Subtype-selective GABAA receptor positive allosteric modulator	[325715-02-4]
L-655,708	Selective for alpha5-containing GABAA receptors	[130477-52-0]
SR 95531 hydrobromide	Selective, competitive GABAA receptor antagonist	[104104-50-9]

About this table

(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Invitrogen, Millipore, and/or Abnova,
siRNAs from Applied Biosystems, Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene,
Tagged/untagged cDNA clones from OriGene,
Expression Assays from Applied Biosystems)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (GABRD)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (GABRD)

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_000815

Sigma-Aldrich siRNA and siRNA Panels for GABRD

Sigma-Aldrich shRNA for GABRD

Explore Sigma-Aldrich super-pooled esiRNAs

Applied Biosystems Silencer® siRNAs:

NM_000815

REFSEQ mRNAs for GABRD gene:

NM_000815.4

Applied Biosystems TaqMan ® Gene Expression Assays:

NM_000815

              OriGene GFP tagged cDNA clone in CMV expression vector: NM_000815
                                 Myc/DDK tagged cDNA clone in CMV expression vector: NM_000815
                                 untagged cDNA clone in CMV expression vector: NM_000815

Additional cDNA sequence:

AF016917.1 AK290861.1 BC033801.1

2 DOTS entries:

DT.95160910 DT.453178

24/35 AceView cDNA sequences (see all 35 ):

NM_000815 BQ951978 BG702804 R88965 BI757807 BM545512 AW594540 AA984687

BI758571 AF016917 BI757337 BI822807 BM547796 AU122311 AW004058 BX279745

BI829118 BI824761 AI828107 BG037021 BC033801 BI490030 AW291520 BQ067322

highest scoring ESTs for GABRD:

AF016917 AI936907 AI445994 AI828107 AU147918 AW004058 AW291520 AW594540 BC033801 BI822807

Unigene Cluster for GABRD:

Gamma-aminobutyric acid (GABA) A receptor, delta

Hs.113882 [show with all ESTs]

Unigene Representative Sequence: NM_000815

GeneLoc Exon Structure

1 Ensembl transcript including schematic representation:

ENST00000378585

(Experimental results according to ¹GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to ²GeneAnnot , ³GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Expression Assays from Applied Biosystems )
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GABRD expression in normal and diseased human tissues

Applied Biosystems TaqMan ® Gene Expression Assays for GABRD

¹ / ² / ³

6 probe-sets matching GABRD gene

Affymetrix probe-set	Array	# genes	Sensitivity	Specificity	Correlation	Length	Gb_Accession	Consensus	Uniqueness	Score	Rank
Affymetrix probe-set	Array	GeneAnnot data			GeneNote data		GeneTide data
35098_at²^{, 3}	U95-A	1	1.00	1.00	0.97	0.90	AF016917	1.00	1.00	1.00	1
91805_at²^{, 3}	U95-E	1	1.00	1.00	0.97	1.10	AI936907	1.00	1.00	1.00	1
230255_at²^{, 3}	U133-B	1	1.00	1.00	--	--	AI936907	1.00	1.00	1.00	1
208457_at²^{, 3}	U133-A	1	1.00	1.00	--	--	NM_000815	0.60	1.00	0.82	1
230255_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--
208457_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--

GeneDecks GABRD for binary patterns associated with the probe-sets selected above

About GeneDecksing

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Data from

(Publications) and GNF BioGPS
About these images
About these images

CGAP SAGE TAG: AAATAAAGCC

SOURCE GeneReport for Unigene cluster: Hs.113882
Expression variation in blood from EXPOLDB for GABRD

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD and/or ⁵MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
About This Section

Orthologs for GABRD gene from 5/9 species (see all 9 )

Organism	Gene	Locus	Description	Human Similarity	NCBI accessions
dog (Canis familiaris)	GABRD¹	--	gamma-aminobutyric acid (GABA) A receptor, delta	87.15(n) 92.06(a)	489609 XM_852752.1 XP_857845.1
chimpanzee (Pan troglodytes)	GABRD¹	--	gamma-aminobutyric acid (GABA) A receptor, delta	98.91(n) 100(a)	747186 XM_001156161.1 XP_001156161.1
cow (Bos taurus)	GABRD¹	--	gamma-aminobutyric acid (GABA) A receptor, delta	89.54(n) 93.5(a)	508711 XM_585530.3 XP_585530.3
rat (Rattus norvegicus)	Gabrd¹	--	gamma-aminobutyric acid (GABA) A receptor, delta	86.56(n) 93.1(a)	29689 NM_017289.1 NP_058985.1
mouse (Mus musculus)	Gabrd^{1, 5}	4⁵	gamma-aminobutyric acid (GABA) A receptor, subunit more⁵ gamma-aminobutyric acid (GABA-A) receptor, subunit more¹	85.67(n)¹ 92.43(a)¹	14403¹ NM_008072.1¹ NP_032098.1¹ AF326546⁵ AF326564⁵ (see all 22)

About this table Species with no ortholog for GABRD

ENSEMBL Gene Tree for GABRD

(Paralogs according to ¹HomoloGene
and ²Ensembl, Pseudogenes according to ³Pseudogene.org)
About This Section

Paralogs for GABRD gene

GABRP² GABRQ²

(According to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
About This Section

10/63 NCBI SNPs in GABRD are shown (see all 63 )
(Click for Applied Biosystems TaqMan ® Genotyping Assay) (see all 15)

AB	SNP ID	Valid	Chr 1 pos	Sequence	Recs	AA Chg	Type	More	Recs	Allele freq	Pop	Total sample	More
AB	Genomic Data				Transcription Data				Allele Frequencies
				--	--	--		--	--				--
--	rs3121818^1,2	A,C	1939404(+)	`AGGCCG/TAGGCG`	1	--	ng5¹		0	--	--	--	--
--	rs16824627^1,2	F	1952493(-)	`TCTGTT/CCCCAA`	1	--	ng3¹		3		NA	142
--	rs7416402^1,2	H	1946287(+)	`AGATCT/CCCTGG`	1	P/S	mis¹ ese³		4		EU EA WA	404
	rs2229110^1,2	C,F	1946897(+)	`CTGGGT/CCTGGA`	1	G/G	syn¹ ese³		2		MN EA	1456
	rs3121819^1,2	A,C,F	1941687(+)	`CATTCG/AGGATC`	1	--	int¹		4		NA EA	362
--	rs3128322^1,2	A,C	1944296(+)	`ACCCCA/GCTGCT`	1	--	int¹		0	--	--	--	--
--	rs3795279^1,2	C,F	1948981(-)	`CCCCTA/GCCCGC`	1	--	int¹		1		EA	1502
--	rs3128318^1,2	A,C	1942642(+)	`CAACTA/CAGCCC`	1	--	int¹		0	--	--	--	--
	rs2376805^1,2	C,F	1946222(-)	`GCCACT/CGGTCA`	1	--	int¹		1		EA	1490
--	rs3128323^1,2	C	1944940(+)	`TCCCGA/GCCCCT`	1	--	int¹		0	--	--	--	--

About this table

HapMap Linkage Disequilibrium images for GABRD (up to first 250kb)

(in which this Gene is Involved, According to OMIM, UniProtKB, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
About This Section

OMIM: 137163

UniProtKB/Swiss-Prot: GBRD_HUMAN, O14764

Defects in GABRD are the cause of susceptibility to generalized epilepsy with febrile

seizures plus type 5 (GEFS+5) [MIM:604233]. Generalized epilepsy with febrile seizures-plus refers

to a rare familial condition with incomplete penetrance and large intrafamilial variability.

Patients display febrile seizures persisting sometimes beyond the age of 6 years and/or a variety

of afebrile seizure types. GEFS+ is a disease combining febrile seizures, generalized seizures

often precipitated by fever at age 6 years or more, and partial seizures, with a variable degree

of severity

Human Gene Mutation Database: GABRD
Genetic Association Database: GABRD
Human Genome Epidemiology Navigator: GABRD (2 documents)

(Possibly Related Articles in Doctor's Guide)
About This Section

(in PubMed. Associations of this gene to articles via ¹Novoseek, ²HGNC, ³Entrez Gene, ⁴UniProtKB/Swiss-Prot, ⁵UniProtKB/TrEMBL, ⁶GAD, and/or ⁷PharmGKB)
About This Section

10/18 PubMed articles for GABRD gene (see all 18 ):

The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)^{3, 4} Gregory S.G.... Bentley D.R. (2006)
Association analysis of the Arg220His variation of the human gene encoding the GABA delta subunit with idiopathic generalized epilepsy. (PubMed id 16023832)^{3, 6} Lenzen K.P....Sander T. (2005)
GABRD encoding a protein for extra- or peri-synaptic GABAA receptors is a susceptibility locus for generalized epilepsies. (PubMed id 15115768)^{3, 4} Dibbens L.M.... Mulley J.C. (2004)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{3, 4} Gerhard D.S....Malek J. (2004)
Assignment of the human GABAA receptor delta-subunit gene (GABRD) to chromosome band 1p36.3 distal to marker NIB1364 by radiation hybrid mapping. (PubMed id 10965146)^{2, 3} Emberger W....Wagner K. (2000)
The murine GABAA receptor delta-subunit gene: structure and assignment to human chromosome 1. (PubMed id 2176788)^{2, 3} Sommer B....Seeburg P.H. (1990)
Altered markers of tonic inhibition in the dorsolateral prefrontal cortex of subjects with schizophrenia. (PubMed id 19289452)³ Maldonado-AvilAcs J.G....Lewis D.A. (2009)
Identification of new putative susceptibility genes for several psychiatric disorders by association analysis of regulatory and non-synonymous SNPs of 306 genes involved in neurotransmission and neurodevelopment. (PubMed id 19086053)³ GratacA^s M....Carracedo A. (2008)
Effect of microdialysis perfusion of 4,5,6,7-tetrahydroisoxazolo-[5,4-c]pyridine-3-ol in the perifornical hypothalamus on sleep-wakefulness: Role of delta-subunit containing extrasynaptic GABA(A) receptors. (PubMed id 18406065)³ Thakkar M.M....McCarley R.W. (2008)
Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)³ Kimura K.... Sugano S. (2006)

(in PubMed, OMIM, and NCBI Bookshelf)
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		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
About This Section

Entrez Gene: 2563	HGNC: 4084	AceView: GABRD	Ensembl:ENSG00000187730	euGenes: HUgn2563
ECgene: GABRD	H-InvDB: GABRD

(According to HUGE)
About This Section

(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Licensable Technologies for GABRD
(Available from WIS Yeda, Salk, Tufts)

About This Section

(Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
Enzo Life Sciences, and/or Tocris Bioscience)
About This Section

Products for GABRD:

TaqMan ® Gene Expression Assays

TaqMan ® Genotyping Assays

Free SNP selection tool

Invitrogen iPath Pathways	Invitrogen BLOCK-iT™ RNAi
Invitrogen Antibodies	Invitrogen Assays
Invitrogen Clones	Invitrogen Q-PCR Products
Invitrogen Human Recombinant Kinases	Invitrogen Custom Antibody and Peptide Service
Invitrogen Proteins / Assays / Screening Services	Search Invitrogen catalog for GABRD-related products

	Millipore Custom Antibody & Bulk Services
	Millipore Preclinical / Clinical Development Services
	Millipore Immunoassay Services
	Millipore Target Screening & Profiling Services

	Predesigned and custom siRNAs for GABRD		Antibodies for GABRD
	Explore super-pooled esiRNAs		Browse proteins at Sigma-Aldrich
	Lentivirus-delivered shRNAs for GABRD		Browse small molecules at Sigma-Aldrich
	"Your Favorite Gene" Pathways		feedback

	Antibodies		Primer Pairs
	Cell Culture Products		ELISAs
	Flow Cytometry Kits		Protease Activity Assays & Reagents
	Cell Selection/Detection Kits & Reagents		ELISA/Assay Development Kits & Reagents
	Multiplex/Array Assay Kits & Reagents		ELISpot Kits & Development Modules
	Recombinant & Natural Proteins

	Search for Recombinant Proteins
	Search for Antibodies
	Chimera RNAi (GABRD)
	Custom Service for Mouse Mab
	Custom Service for Rabbit Pab from Full-length Protein

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	Recombinant Proteins (GABA A Receptor delta)
	Antibodies (GABA A Receptor delta)

Search OriGene for GABRD

Tocris compounds for GABRD

	Drugs for GABRD
	Search www.enzolifesicences.com for proteins, assays, substrates, inhibitors & antibodies

Search Novus for antibodies for GABRD

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GABRD Gene

protein-coding GIFtS: 68

Aliases &
Descriptions
for GABRD

Summaries
for GABRD

Genomic Location
for GABRD

Proteins
for GABRD

Protein Domains/
Families
for GABRD

Gene Function
for GABRD

Pathways & Interactions
for GABRD

Drugs & Compounds
for GABRD

Transcripts
for GABRD

Expression
for GABRD

Orthologs
for GABRD

Paralogs
for GABRD

SNPs/Variants
for GABRD

Disorders & Mutations
for GABRD

Medical News
for GABRD

Publications
for GABRD

Search for GABRD

Genome Databases showing GABRD

Other Databases showing GABRD

Specialized Databases showing GABRD

Licensable Technologies
for GABRD

Services
for GABRD

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

GABRD Gene

protein-coding GIFtS: 68

Aliases & Descriptionsfor GABRD

Summariesfor GABRD

Genomic Locationfor GABRD

Proteinsfor GABRD

Protein Domains/Familiesfor GABRD

Gene Functionfor GABRD

Pathways & Interactionsfor GABRD

Drugs & Compoundsfor GABRD

Transcriptsfor GABRD

Expression for GABRD

Orthologsfor GABRD

Paralogsfor GABRD

SNPs/Variantsfor GABRD

Disorders & Mutationsfor GABRD

Medical Newsfor GABRD

Publicationsfor GABRD

Search for GABRD

Genome Databases showing GABRD

Other Databases showing GABRD

Specialized Databases showing GABRD

Licensable Technologiesfor GABRD

Servicesfor GABRD

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Aliases &
Descriptions
for GABRD

Summaries
for GABRD

Genomic Location
for GABRD

Proteins
for GABRD

Protein Domains/
Families
for GABRD

Gene Function
for GABRD

Pathways & Interactions
for GABRD

Drugs & Compounds
for GABRD

Transcripts
for GABRD

Expression
for GABRD

Orthologs
for GABRD

Paralogs
for GABRD

SNPs/Variants
for GABRD

Disorders & Mutations
for GABRD

Medical News
for GABRD

Publications
for GABRD

Licensable Technologies
for GABRD

Services
for GABRD