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GABPA Gene

protein-coding GIFtS: 63

GC21P026028

GA binding protein transcription factor, alpha subunit 60kDa
(Previous names: GA-binding protein transcription factor, alpha subunit (60kD) )
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc , and/or ⁷Ensembl, ⁸miRBase, and/or ⁹Nature:405,311-319 and CroW21)
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Aliases
E4TF1-60 ^¹, ²
E4TF1A ^¹, ², ³, ⁵
NFT2 ^¹, ²
NRF2 ^¹, ²
NRF2A ^¹, ²
OTTHUMP00000096114 ^²

Descriptions
GA binding protein transcription factor, alpha subunit ^²
GA binding protein transcription factor, alpha subunit 60kDa ^²
GA-binding protein transcription factor, alpha subunit (60kD) ^¹
GABP subunit alpha ^³
Nuclear respiratory factor 2 subunit alpha ^³
Transcription factor E4TF1-60 ^³
human nuclear respiratory factor-2 subunit alpha ^², 9
nuclear respiratory factor 2 alpha subunit ^²

External Ids
HGNC: 4071¹
Entrez Gene: 2551²
UniProtKB: Q06546³
Ensembl: ENSG00000154727⁷

Search outside databases for aliases for GABPA gene

Previous GC identifers: GC21P023686 GC21P026023 GC21P026029

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

EntrezGene summary for GABPA:

This gene encodes one of three GA-binding protein transcription factor subunits which functions as

a DNA-binding subunit. Since this subunit shares identity with a subunit encoding the nuclear

respiratory factor 2 gene, it is likely involved in activation of cytochrome oxidase expression

and nuclear control of mitochondrial function. This subunit also shares identity with a subunit

constituting the transcription factor E4TF1, responsible for expression of the adenovirus E4 gene.

Because of its chromosomal localization and ability to form heterodimers with other polypeptides,

this gene may play a role in the Down Syndrome phenotype. [provided by RefSeq]

UniProtKB/Swiss-Prot: GABPA_HUMAN, Q06546

Function: Transcription factor capable of interacting with purine rich repeats (GA repeats).

Necessary for the expression of the Adenovirus E4 gene

Gene Wiki entry for GABPA

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences, Whole Chromsome Sequence According to Nature (Cited Here with Permission):405,311-319 and CroW21)
About This Section

Genomic View:

UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 21q21-q22.1|21q21.3 Ensembl cytogenetic band: 21q21.3 HGNC cytogenetic band: 21q21-q22.1
Nature(405: 311-319) cytogenetic band: 21q21.3

GABPA Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 21 GeneLoc Exon Structure

(about GC identifiers)

GC21P026028:	GeneLoc	Nature:405,311-319
Start:	26,028,752 bp from pter	12,685,464 bp from centromere
End:	26,066,642 bp from pter	12,719,695 bp from centromere
Size:	37,891 bases	34,232 bases
Orientation:	plus strand	plus strand

RefSeq DNA sequence:

NC_000021.7 NT_011512.10

Whole chromosome sequencing:
cDNA sequence:	U13044 D13318
genomic clones:	pT172

(According to ¹UniProtKB, and/or Ensembl, Phosphorylation sites according to ²Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
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UniProtKB/Swiss-Prot: GABPA_HUMAN, Q06546 (See protein sequence)

Recommended Name: GA-binding protein alpha chain

Size: 454 amino acids; 51295 Da

Subunit: Heterotetramer of two alpha and two beta subunits

Subcellular location: Nucleus

Secondary accessions: Q12939

Post-translational modifications:

View phosphorylation sites using PhosphoSite²

REFSEQ proteins: NP_002031.2

ENSEMBL proteins:

ENSP00000346886 ENSP00000382948

Human Recombinant Proteins

	Browse Drug Discovery Central at Invitrogen for human recombinant proteins
	Browse Purified and Recombinant Proteins at Millipore
	Browse Human Recombinant Proteins at Sigma-Aldrich
	Browse R&D Systems for human recombinant proteins
	Browse recombinant and purified proteins available from Enzo Life Sciences
	Recombinant Proteins from Abcam (GABPA)
	Human Recombinant Proteins from Abnova (GABPA)

OriGene Purified Recombinant Human Protein: GABPA

2 Gene Ontology (GO) cellular component terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005634	nucleus	TAS	9016666
GO:0005730	NOT nucleolus	IDA	18029348

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Antibodies for GABPA:

	Browse Antibodies Central at Invitrogen
	Browse Millipore's Extensive Line of Mono- and Polyclonal Antibodies
	Sigma-Aldrich Antibodies for GABPA
	Browse R&D Systems for Antibodies
	Antibodies from Abcam (GABPA), each with their Abpromise^SM
	Monoclonal and Polyclonal Antibodies from Abnova (GABPA)
	Novus Biologicals Antibodies for GABPA

Assays for GABPA:

	Browse Invitrogen for biochemical assays
	Browse Kits and Assays available from Millipore
	Browse R&D Systems for biochemical assays
	Browse biochemical assays available from Enzo Life Sciences

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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Graphical View of Domain Structure for InterPro Entry Q06546

ProtoNet protein and cluster: Q06546

1 Blocks protein family: IPB003118 Sterile alpha motif (SAM)/Pointed domain

UniProtKB/Swiss-Prot: GABPA_HUMAN, Q06546

Similarity: Belongs to the ETS family

Similarity: Contains 1 ETS DNA-binding domain

Similarity: Contains 1 PNT (pointed) domain

(According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
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Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (GABPA)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (GABPA)

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_002040

Applied Biosystems Silencer® siRNAs for GABPA

Sigma-Aldrich siRNA for GABPA

Sigma-Aldrich shRNA for GABPA

Explore Sigma-Aldrich super-pooled esiRNAs

Clones:		Invitrogen Clones for GABPA
		Browse Clones for the Expression of Recombinant Proteins Available from Millipore

OriGene GFP tagged cDNA clone in CMV expression vector: NM_002040
Myc/DDK tagged cDNA clone in CMV expression vector: NM_002040
untagged cDNA clone in CMV expression vector: NM_002040

Primers:

Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers

OriGene genome-wide validated SYBR primer pairs: NM_002040

UniProtKB/Swiss-Prot: GABPA_HUMAN, Q06546

Function: Transcription factor capable of interacting with purine rich repeats (GA repeats).

Necessary for the expression of the Adenovirus E4 gene

Genatlas biochemistry entry for GABPA:

GA binding protein,alpha subunit with an ETS related domain,component of the nuclear respiratory

factor 2,ubiquitously expressed,interacting with the four ankyrin-type repeats to form a high

affinity DNA-binding complex recognizing an important site for herpes simplex virus type I

activation,putatively involved in the activation of nuclear genes specifying mitochondrial

function

11 MGI mutant phenotypes (inferred from 7 alleles) (MGI details for Gabpa):

cellular	embryogenesis	growth/size	hematopoietic system	homeostasis/metabolism
immune system	lethality-prenatal/perinatal	muscle	nervous system	no phenotypic analysis
normal

5 Gene Ontology (GO) molecular function terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0003700	transcription factor activity	TAS	7590737 8441384
GO:0003702	RNA polymerase II transcription factor activity	TAS	8441384
GO:0003713	transcription coactivator activity	TAS	8441384
GO:0005515	protein binding	IPI	10675337
GO:0043565	sequence-specific DNA binding	IEA	--

About this table

(Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to ¹UniProtKB, ²MINT, and/or ³STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
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1 Sigma-Aldrich "Your Favorite Gene" Pathway for GABPA (Your Favorite Gene powered by Ingenuity)

Agrin Interactions at Neuromuscular Junction

GeneDecks GABPA for the pathways selected above

About GeneDecksing

Gene Network Central^TM Interacting Genes and Proteins Network for GABPA

5/11 Interacting proteins for GABPA (ENSP00000346886³ Q06546^{1, 2}) via UniProtKB, MINT, and/or STRING (see all 11 )

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
HCFC1	P51610¹	STRING (score=.775) EBI-638925, EBI-396176
SP1	P08047²	MINT-49851 MINT-49852
SP3	Q02447²	MINT-49853 MINT-49854
GABPB1	ENSP00000370259³	STRING (score=.985)
A1BG	ENSP00000263100³	STRING (score=.951)

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3 Gene Ontology (GO) biological process terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0000122	negative regulation of transcription from RNA polymerase II promoter	IEA	--
GO:0001701	in utero embryonic development	IEA	--
GO:0006350	transcription	IEA	--

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(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
About This Section

Browse drugs & compounds from Enzo Life Sciences

Browse Small Molecules at Sigma-Aldrich

Browse Tocris compounds for GABPA
5 Novoseek chemical compound relationships for GABPA gene

Compound	Score	Articles	PubMed IDs for Articles with Shared Sentences (# sentences)
diethylmaleate	59.93	7	15521073 (1), 17077087 (1), 15379550 (1)
oxygen	17.42	1	17077087 (1)
atp	0.55	3	1656236 (2), 12539966 (1)
lipid	0.00	2	18230803 (1)
calcium	0.00	2	12665481 (2)

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(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Invitrogen, Millipore, and/or Abnova,
siRNAs from Applied Biosystems, Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene,
Tagged/untagged cDNA clones from OriGene,
Expression Assays from Applied Biosystems)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (GABPA)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (GABPA)

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_002040

Sigma-Aldrich siRNA for GABPA

Sigma-Aldrich shRNA for GABPA

Explore Sigma-Aldrich super-pooled esiRNAs

Applied Biosystems Silencer® siRNAs:

NM_002040

REFSEQ mRNAs for GABPA gene:

NM_002040.3

Applied Biosystems TaqMan ® Gene Expression Assays:

NM_002040

              OriGene GFP tagged cDNA clone in CMV expression vector: NM_002040
                                 Myc/DDK tagged cDNA clone in CMV expression vector: NM_002040
                                 untagged cDNA clone in CMV expression vector: NM_002040

Additional cDNA sequence:

AK223164.1 AK313545.1 BC035031.2 BX647755.1 D13318.1 EU159453.1 U13044.1 X84366.1

10 DOTS entries:

DT.99933995 DT.99992826 DT.100727081 DT.453987 DT.121138154 DT.121138106 DT.121137994 DT.121138144

DT.92407558 DT.121079420

24/135 AceView cDNA sequences (see all 135 ):

AU107258 AW105605 BU188528 AU107257 BI826069 AI624911 BM477941 AI075824

BQ216320 CA392232 BU683067 BM977191 NM_002040 BX647755 AA730256 BQ423139

AA489598 AA935134 AA946680 BQ023312 BM464174 AI684289 T93885 X84366

highest scoring ESTs for GABPA:

AI917898 U13044 AA173607 AA377097 AA497016 AA628753 AA704298 AA730256 AA780954 AA897458

Unigene Cluster for GABPA:

GA binding protein transcription factor, alpha subunit 60kDa

Hs.473470 [show with all ESTs]

Unigene Representative Sequence: BX647755

GeneLoc Exon Structure

2 Ensembl transcripts including schematic representations:

ENST00000354828 ENST00000400075

(Experimental results according to ¹GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to ²GeneAnnot , ³GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Expression Assays from Applied Biosystems )
About This Section

GABPA expression in normal and diseased human tissues

Applied Biosystems TaqMan ® Gene Expression Assays for GABPA

¹ / ² / ³

6 probe-sets matching GABPA gene

Affymetrix probe-set	Array	# genes	Sensitivity	Specificity	Correlation	Length	Gb_Accession	Consensus	Uniqueness	Score	Rank
Affymetrix probe-set	Array	GeneAnnot data			GeneNote data		GeneTide data
62479_at²^{, 3}	U95-C	1	1.00	1.00	0.91	1.25	AI917898	1.00	1.00	1.00	1
37245_at²^{, 3}	U95-A	1	0.94	1.00	0.74	0.75	U13044	1.00	1.00	1.00	1
210188_at²^{, 3}	U133-A	1	1.00	1.00	--	--	D13318	0.80	1.00	0.91	1
227428_at²^{, 3}	U133-B	1	1.00	1.00	--	--	BE876628	0.80	1.00	0.91	1
210188_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--
227428_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--

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Data from

(Publications) and GNF BioGPS
About these images
About these images

CGAP SAGE TAG: TGAAGTTTTT

SOURCE GeneReport for Unigene cluster: Hs.473470
Expression variation in blood from EXPOLDB for GABPA

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD and/or ⁵MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
About This Section

Orthologs for GABPA gene from 5/12 species (see all 12 )

Organism	Gene	Locus	Description	Human Similarity	NCBI accessions
dog (Canis familiaris)	GABPA¹	--	GA binding protein transcription factor, alpha subunit more	93.54(n) 99.12(a)	478394 XM_535570.2 XP_535570.1
chimpanzee (Pan troglodytes)	GABPA¹	--	GA binding protein transcription factor, alpha subunit more	99.93(n) 100(a)	474079 XM_001157517.1 XP_001157517.1
cow (Bos taurus)	GABPA¹	--	GA binding protein transcription factor, alpha subunit more	93.25(n) 98.68(a)	510204 NM_001075437.1 NP_001068905.1
rat (Rattus norvegicus)	Gabpa¹	--	GA binding protein transcription factor, alpha subunit	90.9(n) 98.24(a)	363735 XM_344002.3 XP_344003.2
mouse (Mus musculus)	Gabpa^{1, 5}	16 (55.00 cM)⁵	GA repeat binding protein, alpha^{1, 5}	89.7(n)¹ 96.25(a)¹	14390¹ NM_008065.2¹ NP_032091.2¹ AF156797⁵ AF346288⁵ (see all 26)

About this table Species with no ortholog for GABPA

ENSEMBL Gene Tree for GABPA

(Paralogs according to ¹HomoloGene
and ²Ensembl, Pseudogenes according to ³Pseudogene.org)
About This Section

Paralogs for GABPA gene

ETS2² ELK1² ETS1²

(According to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
About This Section

10/299 NCBI SNPs in GABPA are shown (see all 299 )
(Click for Applied Biosystems TaqMan ® Genotyping Assay) (see all 59)

AB	SNP ID	Valid	Chr 21 pos	Sequence	Recs	AA Chg	Type	More	Recs	Allele freq	Pop	Total sample	More
AB	Genomic Data				Transcription Data				Allele Frequencies
				--	--	--		--	--				--
--	rs2829897^1,2	C,F,H,O	26058461(+)	`TAGTGC/TGAAAG`	1	A/V	mis¹ ese³		7		NA EU WA EA	670
--	rs2829900^1,2	C,F,O	26058866(+)	`GTGATG/AAAGGT`	1	K/E	mis¹		5		NA EU EA WA	436
--	rs11910413^1,2	C,F,H	26065150(+)	`TATTAG/ATACAA`	1	--	ut3¹ ese³		4		EU EA WA	414
	rs2829898^1,2	F,O	26058802(+)	`CTATGG/ACAGTT`	1	X/W	non¹ ese³		1		NA	17
--	rs2154472^1,2	C	26065033(+)	`ACTAAA/TACATG`	1	--	ut3¹ ese³		0	--	--	--	--
--	rs11910425^1,2	C	26065419(+)	`ATGATA/GGACAT`	1	--	ut3¹		0	--	--	--	--
--	rs2694^1,2	F	26063609(+)	`TGTGTG/ATGTTA`	1	--	ut3¹ ese³		1		MN	184
--	rs2829901^1,2	F,O	26058907(+)	`GCACAA/GAAATG`	1	Q/Q	syn¹ ese³		1		NA	15
--	rs2829899^1,2	F,O	26058847(+)	`GACTGC/TATTTC`	1	C/C	syn¹ ese³		1		NA	16
--	rs9981487^1,2	C	26043259(+)	`AAAACA/GGATGG`	1	T/T	syn¹ ese³		1		NA	76

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HapMap Linkage Disequilibrium images for GABPA (up to first 250kb)

(in which this Gene is Involved, According to OMIM, UniProtKB, Novoseek, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
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OMIM: 600609

1 Novoseek disease relationship for GABPA gene

Disease	Score	Articles	PubMed IDs for Articles with Shared Sentences (# sentences)
neurodegenerative diseases	28.14	1	18824091 (1)

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Genetic Association Database: GABPA
Human Genome Epidemiology Navigator: GABPA (2 documents)

(Possibly Related Articles in Doctor's Guide)
About This Section

(in PubMed. Associations of this gene to articles via ¹Novoseek, ²HGNC, ³Entrez Gene, ⁴UniProtKB/Swiss-Prot, ⁵UniProtKB/TrEMBL, ⁶GAD, and/or ⁷PharmGKB)
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10/104 PubMed articles for GABPA gene (see all 104 ):

cDNA cloning of transcription factor E4TF1 subunits with Ets and notch motifs. (PubMed id 8441384)^{2, 3, 4} Watanabe H.... Handa H. (1993)
Identification of polymorphisms in the promoter region of the human NRF2 gene. (PubMed id 15358217)^{1, 3, 6} Yamamoto T....Yamamoto M. (2004)
Four structurally distinct, non-DNA-binding subunits of human nuclear respiratory factor 2 share a conserved transcriptional activation domain. (PubMed id 7799916)^{1, 3, 4} Gugneja S.... Scarpulla R.C. (1995)
In vitro methylation of nuclear respiratory factor-2 binding sites suppresses the promoter activity of the human TOMM70 gene. (PubMed id 18852034)^{1, 3} Blesa J.R....Hernandez-Yago J. (2008)
Mapping of the human transcription factor GABPA (E4TF1-60) gene to chromosome 21. (PubMed id 7590737)^{1, 3} Chrast R....Antonarakis S.E. (1995)
Human nuclear respiratory factor 2 alpha subunit cDNA: isolation, subcloning, sequencing, and in situ hybridization of transcripts in normal and monocularly deprived macaque visual system. (PubMed id 10660899)^{1, 3} Guo A....Wong-Riley M. (2000)
Nuclear respiratory factor 2 activates transcription of human mitochondrial translation initiation factor 2 gene. (PubMed id 17161026)^{1, 3} Hayashi R....Takeuchi N. (2007)
Activation of synoviolin promoter in rheumatoid synovial cells by a novel transcription complex of interleukin enhancer binding factor 3 and GA binding protein alpha. (PubMed id 19116932)^{1, 3} Izumi T....Nakajima T. (2009)
Assignment of the E4TF1-60 gene to human chromosome 21q21.2-q21.3. (PubMed id 8543189)^{1, 3} Goto M....Handa H. (1995)
Toward a confocal subcellular atlas of the human proteome. (PubMed id 18029348)³ Barbe L....Andersson-Svahn H. (2008)

(in PubMed, OMIM, and NCBI Bookshelf)
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		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
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Entrez Gene: 2551	HGNC: 4071	AceView: GABPA	Ensembl:ENSG00000154727	euGenes: HUgn2551
ECgene: GABPA	H-InvDB: GABPA

(According to HUGE)
About This Section

(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Licensable Technologies for GABPA
(Available from WIS Yeda, Salk, Tufts)

About This Section

(Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
Enzo Life Sciences, and/or Tocris Bioscience)
About This Section

Products for GABPA:

TaqMan ® Gene Expression Assays

TaqMan ® Genotyping Assays

Free SNP selection tool

Invitrogen iPath Pathways	Invitrogen BLOCK-iT™ RNAi
Invitrogen Antibodies	Invitrogen Assays
Invitrogen Clones	Invitrogen Q-PCR Products
Invitrogen Human Recombinant Kinases	Invitrogen Custom Antibody and Peptide Service
Invitrogen Proteins / Assays / Screening Services	Search Invitrogen catalog for GABPA-related products

	Millipore Custom Antibody & Bulk Services
	Millipore Preclinical / Clinical Development Services
	Millipore Immunoassay Services
	Millipore Target Screening & Profiling Services

	Predesigned and custom siRNAs for GABPA		Antibodies for GABPA
	Explore super-pooled esiRNAs		Browse proteins at Sigma-Aldrich
	Lentivirus-delivered shRNAs for GABPA		Browse small molecules at Sigma-Aldrich
	"Your Favorite Gene" Pathways		feedback

	Antibodies		Primer Pairs
	Cell Culture Products		ELISAs
	Flow Cytometry Kits		Protease Activity Assays & Reagents
	Cell Selection/Detection Kits & Reagents		ELISA/Assay Development Kits & Reagents
	Multiplex/Array Assay Kits & Reagents		ELISpot Kits & Development Modules
	Recombinant & Natural Proteins

	Recombinant Proteins (GABPA)
	Antibodies (GABPA)
	Chimera RNAi (GABPA)
	Custom Service for Mouse Mab
	Custom Service for Rabbit Pab from Full-length Protein

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	Recombinant Proteins (GABPA)
	Antibodies (GABPA)

	Tagged/untagged cDNA clones
	Validated SYBR primer pairs
	Purified proteins from HEK293T cells
	Western blot validated antibodies
	shRNA in GFP-retroviral vector

Search Tocris compounds for GABPA

Search www.enzolifesicences.com for proteins, assays, substrates, inhibitors & antibodies

Antibodies for GABPA

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GABPA Gene

protein-coding GIFtS: 63

Aliases &
Descriptions
for GABPA

Summaries
for GABPA

Genomic Location
for GABPA

Proteins
for GABPA

Protein Domains/
Families
for GABPA

Gene Function
for GABPA

Pathways & Interactions
for GABPA

Drugs & Compounds
for GABPA

Transcripts
for GABPA

Expression
for GABPA

Orthologs
for GABPA

Paralogs
for GABPA

SNPs/Variants
for GABPA

Disorders & Mutations
for GABPA

Medical News
for GABPA

Publications
for GABPA

Search for GABPA

Genome Databases showing GABPA

Other Databases showing GABPA

Specialized Databases showing GABPA

Licensable Technologies
for GABPA

Services
for GABPA

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

GABPA Gene

protein-coding GIFtS: 63

Aliases & Descriptionsfor GABPA

Summariesfor GABPA

Genomic Locationfor GABPA

Proteinsfor GABPA

Protein Domains/Familiesfor GABPA

Gene Functionfor GABPA

Pathways & Interactionsfor GABPA

Drugs & Compoundsfor GABPA

Transcriptsfor GABPA

Expression for GABPA

Orthologsfor GABPA

Paralogsfor GABPA

SNPs/Variantsfor GABPA

Disorders & Mutationsfor GABPA

Medical Newsfor GABPA

Publicationsfor GABPA

Search for GABPA

Genome Databases showing GABPA

Other Databases showing GABPA

Specialized Databases showing GABPA

Licensable Technologiesfor GABPA

Servicesfor GABPA

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Aliases &
Descriptions
for GABPA

Summaries
for GABPA

Genomic Location
for GABPA

Proteins
for GABPA

Protein Domains/
Families
for GABPA

Gene Function
for GABPA

Pathways & Interactions
for GABPA

Drugs & Compounds
for GABPA

Transcripts
for GABPA

Expression
for GABPA

Orthologs
for GABPA

Paralogs
for GABPA

SNPs/Variants
for GABPA

Disorders & Mutations
for GABPA

Medical News
for GABPA

Publications
for GABPA

Licensable Technologies
for GABPA

Services
for GABPA