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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

GABARAP Gene

protein-coding   GIFtS: 62
GCID: GC17M007143

GABA(A) receptor-associated protein

 Explore 10 diseases affiliated with
GABARAP via our new
 Human Malady Compendium 
Biological research products
for GABARAP
    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section

Aliases
GABA(A) Receptor-Associated Protein1 2 3
MM461 2 3
ATG8A1 2
GABARAP-A1
Gamma-Aminobutyric Acid Receptor-Associated Protein2
FLC3B3

External Ids:    HGNC: 40671   Entrez Gene: 113372   Ensembl: ENSG000001702967   OMIM: 6051255   UniProtKB: O951663   

Export aliases for GABARAP gene to outside databases

Previous GC identifers: GC16M055704 GC17M007873 GC17M007086 GC17M007344 GC17M007084 GC17M007035


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for GABARAP:
Gamma-aminobutyric acid A receptors (GABA(A) receptors) are ligand-gated chloride channels that mediate inhibitory
neurotransmission. This gene encodes GABA(A) receptor-associated protein, which is highly positively charged in its
N-terminus and shares sequence similarity with light chain-3 of microtubule-associated proteins 1A and 1B. This
protein clusters neurotransmitter receptors by mediating interaction with the cytoskeleton. (provided by RefSeq, Jul
2008)

UniProtKB/Swiss-Prot: GBRAP_HUMAN, O95166
Function: May play a role in intracellular transport of GABA(A) receptors and its interaction with the cytoskeleton.
Involved in apoptosis. Involved in autophagy (By similarity)

Gene Wiki entry for GABARAP


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000017.10  NC_018928.1  NT_010718.16  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the GABARAP gene promoter:
         COUP-TF1   AP-2alpha isoform 3   COUP   HNF-4alpha2   AP-2alpha isoform 2   HNF-4alpha1   COUP-TF   AP-2alpha isoform 4   AP-2alpha   AP-2alphaA   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidGABARAP promoter sequence
   Search SABiosciences Chromatin IP Primers for GABARAP

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat GABARAP


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 17p13.1   Ensembl cytogenetic band:  17p13.1   HGNC cytogenetic band: 17p13.1

GABARAP Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
GABARAP gene location

GeneLoc information about chromosome 17         GeneLoc Exon Structure

GeneLoc location for GC17M007143:  view genomic region     (about GC identifiers)

Start:
7,143,333 bp from pter      End:
7,146,089 bp from pter
Size:
2,757 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: GBRAP_HUMAN, O95166 (See protein sequence)
Recommended Name: Gamma-aminobutyric acid receptor-associated protein  
Size: 117 amino acids; 13918 Da
Subunit: Interacts with GPHN and NSF (By similarity). Interacts with GABRG2, beta-tubulin and ULK1. Interacts with
CALR. Interacts with DDX47. Interacts with TP53INP1 and TP53INP2. Interacts with TBC1D25. Directly interacts with
SQSTM1
Subcellular location: Endomembrane system (By similarity). Cytoplasm, cytoskeleton (By similarity). Golgi apparatus
membrane (By similarity). Cytoplasmic vesicle, autophagosome. Note=Largely associated with intracellular membrane
structures including the Golgi apparatus and postsynaptic cisternae. Colocalizes with microtubules (By similarity)
6 PDB 3D structures from and Proteopedia for GABARAP:
1GNU (3D)        1KLV (3D)        1KM7 (3D)        1KOT (3D)        3D32 (3D)        3DOW (3D)    

Explore the universe of human proteins at neXtProt for GABARAP: NX_O95166

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_O95166

  • GABARAP Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins: NP_009209.1  
    ENSEMBL proteins: 
     ENSP00000306866   ENSP00000460855   ENSP00000460489   ENSP00000461882   ENSP00000459345  
     ENSP00000458476  

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    Uscn Proteins for GABARAP

    Gene Ontology (GO): 5/13 cellular component terms (GO ID links to tree view) (see all 13):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000139Golgi membrane IEA--
    GO:0000421autophagic vacuole membrane IDA15169837
    GO:0005764lysosome IEA--
    GO:0005776autophagic vacuole IDA19056683
    GO:0005790smooth endoplasmic reticulum IEA--


    GABARAP for ontologies           About GeneDecksing



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    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    GABARAP for domains           About GeneDecksing

    1 InterPro domain/family:
     IPR004241 Atg8_ubiquitin-like

    Graphical View of Domain Structure for InterPro Entry O95166

    ProtoNet protein and cluster: O95166

    1 Blocks protein family: IPB004241 Light chain 3 (LC3)

    UniProtKB/Swiss-Prot: GBRAP_HUMAN, O95166
    Similarity: Belongs to the MAP1 LC3 family


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section

    Function Summary:

         UniProtKB/Swiss-Prot: GBRAP_HUMAN, O95166
    Function: May play a role in intracellular transport of GABA(A) receptors and its interaction with the cytoskeleton.
    Involved in apoptosis. Involved in autophagy (By similarity)

         Genatlas biochemistry entry for GABARAP:
    GABA (A) receptor-associated protein binding GABA-A receptors,gamma 2 subunit and linking the receptors to the
    cytoskeleton,highly homolog to microtubule associated proteins 1A and 1B ganglioside expression factor homolog 2

    miRNA
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    Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI--
    GO:0008017microtubule binding IEA--
    GO:0048487beta-tubulin binding IDA9892355
    GO:0050811GABA receptor binding IPI9892355


    GABARAP for ontologies           About GeneDecksing


    Animal Models:
         1 MGI mutant phenotype (inferred from 2 alleles(MGI details for Gabarap):
     normal 

    GABARAP for phenotypes           About GeneDecksing


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways  About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1Senescence and Autophagy
    Senescence and Autophagy1.00
    2Regulation of IFNA signaling
    Regulation of autophagy0.26

    Pathway sources
    See GeneCards unified pathways
    Show all pathways


    1 BioSystems Pathway for GABARAP 
        Senescence and Autophagy


    1         Kegg Pathway  (Kegg details for GABARAP):
        Regulation of autophagy


    GABARAP for pathways           About GeneDecksing

    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for GABARAP

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/656 Interacting proteins for GABARAP (O951661, 2, 3 ENSP000003068664) via UniProtKB, MINT, STRING, and/or I2D (see all 656)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    HIST1H4AP628053I2D: score=1 
    HIST1H4BP628053I2D: score=1 
    HIST1H4CP628053I2D: score=1 
    HIST1H4DP628053I2D: score=1 
    HIST1H4EP628053I2D: score=1 
    About this table

    Gene Ontology (GO): 5 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000226microtubule cytoskeleton organization IEA--
    GO:0006605protein targeting TAS9892355
    GO:0006914autophagy IEA--
    GO:0006915apoptotic process IDA15977068
    GO:0007268synaptic transmission TAS9892355


    GABARAP for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section

    GABARAP for compounds           About GeneDecksing

    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for GABARAP

    1 HMDB Compound for GABARAP    About this table
    CompoundSynonyms CAS #PubMed Ids
    Gamma-Aminobutyric acid3-Carboxypropylamine (see all 27)56-12-2--
    3 Novoseek chemical compound relationships for GABARAP gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    gaba 70.2 45 9892355 (3), 18160640 (3), 15007071 (2), 16954214 (2) (see all 20)
    n-ethylmaleimide 42.6 3 15065816 (1), 11779480 (1), 18464608 (1)
    diazepam 38.4 3 19703932 (2), 15007071 (1)

    Search CenterWatch for drugs/clinical trials and news about GABARAP / GBRAP 

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for GABARAP gene: 
    NM_007278.1  

    Unigene Cluster for GABARAP:

    GABA(A) receptor-associated protein
    Hs.647421  [show with all ESTs]
    Unigene Representative Sequence: BM803698
    6 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000302386(uc002gfb.3) ENST00000577035 ENST00000570856 ENST00000571129
    ENST00000571253 ENST00000573928

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    hsa-miR-4303 hsa-miR-455-5p hsa-miR-550a hsa-miR-2114 hsa-miR-3606 hsa-miR-1321 hsa-miR-4306 hsa-miR-876-3p
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    Additional cDNA sequence: 

    AB030711.1 AF044671.1 AF067171.1 AF161586.1 AF183425.1 AK098634.1 AK312205.1 AL050182.1 
    BC106748.1 BC106749.1 CR457043.1 CR542235.1 JN663880.1 

    24/28 DOTS entries (see all 28):

    DT.99926443  DT.91773251  DT.100649015  DT.449606  DT.101985433  DT.120968722  DT.120968637  DT.91773230 
    DT.99937435  DT.120968554  DT.120968747  DT.120968788  DT.75111082  DT.100848809  DT.95271157  DT.120968638 
    DT.120968758  DT.95271171  DT.450749  DT.95127999  DT.95271155  DT.100848801  DT.120968719  DT.91773237 

    24/672 AceView cDNA sequences (see all 672):

    CA442960 AI587171 CF130158 CR609735 BM764363 AA903542 BX384546 BU735821 
    BM999373 AA284321 H45728 AW511436 BU856629 BM450012 AW571512 AA678902 
    BF529506 CR625645 BQ962375 BE049250 AA954681 BE855808 BM971531 AA838218 

    GeneLoc Exon Structure

    4 Alternative Splicing Database (ASD) splice patterns (SP) for GABARAP    About this scheme

    ExUns: 1a · 1b ^ 2a · 2b ^ 3a · 3b ^ 4a · 4b
    SP1:              -                 -               
    SP2:              -                                 
    SP3:              -     -           -               
    SP4:                                -               


    ECgene alternative splicing isoforms for GABARAP

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    GABARAP expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: AAGAAGACTT

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)

    About this image
    See GABARAP Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for GABARAP

    SOURCE GeneReport for Unigene cluster: Hs.647421

    UniProtKB/Swiss-Prot: GBRAP_HUMAN, O95166
    Tissue specificity: Heart, brain, placenta, liver, skeletal muscle, kidney and pancreas

        SABiosciences Expression via Pathway-Focused PCR Array including GABARAP: 
              Autophagy in human mouse rat

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    In Situ
    Assay Products:
     

     
    Search Advanced Cell Diagnostics for RNAscope RNA in situ hybridization assays for GABARAP

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for GABARAP gene from 8/29 species (see all 29)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    chicken
    (Gallus gallus)
    Aves E1C2J6_CHICK6
    Uncharacterized protein
    86(a)
    possible ortholog
    1(81563191-81580165)
    lizard
    (Anolis carolinensis)
    Reptilia GABARAPL16
    --
    82(a)
    possible ortholog
    2(81871037-81892754)
    zebrafish
    (Danio rerio)
    Actinopterygii gabarapa1 GABA(A) receptor-associated protein a 81.9(n)
    98.28(a)
      326974  NM_001013260.1  NP_001013278.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG123343
    Atg8a1
    Autophagy-specific gene 8a1 77(a)3
    76.64(n)1
    91.45(a)1
      90C23
    320011  NM_167245.21  NP_727447.11 
    worm
    (Caenorhabditis elegans)
    Secernentea lgg-11 , 3 Protein LGG-11 83(a)3
    74.14(n)1
    83.62(a)1
      II(6346634-6347795)3
    1740501  NM_062876.41  NP_495277.11 
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes ATG81 Atg8p 54.6(n)
    55.17(a)
      852200   NP_009475.1 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons ATG8D1 GABA(A) receptor-associated protein (autophagy-related more 58.41(n)
    57.52(a)
      815112  NM_126586.3  NP_178631.1 
    rice
    (Oryza sativa)
    Liliopsida --
    --
    (see all 5)
    autophagy-related protein, putative, expressed
    (see all 5)
    56(a)
    54(a)
    (see all 5)
    possible ortholog
    possible ortholog
    (see all 5)
    8(5363352-5365506)
    4(31531261-31534066)


    ENSEMBL Gene Tree for GABARAP (if available)
    TreeFam Gene Tree for GABARAP (if available) 

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for GABARAP gene
    GABARAPL22  MAP1LC3B2  MAP1LC3C2  MAP1LC3A2  GABARAPL32  MAP1LC3B22  GABARAPL12  
    9 SIMAP similar genes for GABARAP using alignment to 5 protein entries:     GBRAP_HUMAN (see all proteins):
    DKFZp586A1923    GABARAPL3    GABARAPL1    GABARAPL2    DKFZp762B153    MAP1LC3B2
    MAP1LC3A    MAP1LC3B    MAP1LC3C

    GABARAP for paralogs           About GeneDecksing


    2 Pseudogenes.org Pseudogenes for GABARAP
    PGOHUM00000239887 PGOHUM00000245177


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/90 NCBI SNPs in GABARAP are shown (see all 90    About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 17 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1807863251,2
    --7143394(+) TAGCAA/CATGTG 2 -- ds5001 us2k10--------
    rs1463700231,2
    --7143418(+) AGCAGA/GTACTT 2 -- us2k1 ds50010--------
    rs800674661,2
    F,--7143424(+) TACTTC/TGGAAC 2 -- ds5001 us2k11Minor allele frequency- T:0.02EA 120
    rs1862198791,2
    --7143717(+) GGGGAG/TCAACA 2 -- us2k1 ds50010--------
    rs413018091,2
    C--7143729(+) AAGGCA/TAAATT 2 -- us2k1 ds50010--------
    rs31772091,2
    C--7143748(-) AAACCA/CCCAAG 2 -- ut31 us2k1 ese32Minor allele frequency- C:0.00NA 4
    rs456186361,2
    C,--7143838(+) AGGAAG/AGGATT 2 -- ut31 us2k12Minor allele frequency- A:0.03NA WA 120
    rs1919329181,2
    --7143943(+) CAGGAC/TGGGAA 2 -- ut31 us2k10--------
    rs1834413411,2
    --7143977(+) AAGGAC/GAAAGG 2 -- ut31 us2k10--------
    rs177101,2
    C,F,A,H,--7143994(-) TGGCAT/ACTTGT 2 -- ut31 us2k1 ese312Minor allele frequency- A:0.06NA MN NS EA 874

    HapMap Linkage Disequilibrium report for GABARAP (7143333 - 7146089 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
          Database of Genomic Variants (DGV) variations for GABARAP: --

    SABiosciences Cancer Mutation PCR Assays
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    GABARAP for disorders           About GeneDecksing

    OMIM gene information: 605125    OMIM disorders: --

    10 diseases for GABARAP:    About MalaCards
    stiff-person syndrome    nicotine dependence    essential tremor    tremor
    fibrosarcoma    colorectal cancer    breast cancer    neuroblastoma
    malaria    neuronitis

    1 disease from the University of Copenhagen DISEASES database for GABARAP:
    Stiff-Person syndrome

    1 Novoseek disease relationship for GABARAP gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    tumors 0 1 19617690 (1)

    Human Genome Epidemiology (HuGE) Navigator: GABARAP (3 documents)

    Export disorders for GABARAP gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for GABARAP gene, integrated from 9 sources (see all 99):
    (articles sorted by number of sources associating them with GABARAP)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. GABA(A)-receptor-associated protein links GABA(A) receptors and the cytoskeleton. (PubMed id 9892355)1, 2, 3, 9 Wang H.... Olsen R.W. (1999)
    2. The X-ray crystal structure and putative ligand-derived peptide binding properties of gamma-aminobutyric acid receptor type A receptor-associated protein. (PubMed id 11729197)1, 2, 9 Knight D.... Keep N.H. (2002)
    3. Structural framework of the GABARAP-calreticulin interface--implications for substrate binding to endoplasmic reticulum chaperones. (PubMed id 19154346)1, 2, 9 Thielmann Y....Willbold D. (2009)
    4. Solution structure of human GABA(A) receptor-associated protein GABARAP: implications for biolgoical funcrion and its regulation. (PubMed id 11875056)1, 2, 9 Stangler T.... Willbold D. (2002)
    5. The TP53INP2 protein is required for autophagy in mammalian cells. (PubMed id 19056683)1, 2, 9 Nowak J....Iovanna J.L. (2009)
    6. 1H, 13C and '5N resonance assignments of GABARAP, GABAA receptor associated protein. (PubMed id 11885988)1, 2, 9 Kouno T.... Kawano K. (2002)
    7. OATL1, a novel autophagosome-resident Rab33B-GAP, reg ulates autophagosomal maturation. (PubMed id 21383079)1, 2 Itoh T....Fukuda M. (2011)
    8. Ligand binding mode of GABAA receptor-associated protein. (PubMed id 18638487)1, 2 Weiergraber O.H....Willbold D. (2008)
    9. GABAA receptor-associated protein (GABARAP) induces apoptosis by interacting with DEAD (Asp-Glu-Ala-Asp/His) box polypeptide 47 (DDX 47). (PubMed id 15977068)1, 2 Lee J.H....Chun T. (2005)
    10. Gene expression profiling in the human hypothalamus-pituitary-adrenal axis and full-length cDNA cloning. (PubMed id 10931946)1, 2 Hu R.-M.... Chen J.-L. (2000)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Disorders
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 11337 HGNC: 4067 AceView: CLDN7andGABARAPandDULLARD Ensembl:ENSG00000170296 euGenes: HUgn11337
    ECgene: GABARAP Kegg: 11337 H-InvDB: GABARAP

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for GABARAP Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for GABARAP gene:
    Search GeneIP for patents involving GABARAP

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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