Aliases for GAB3 Gene
External Ids for GAB3 Gene
Previous GeneCards Identifiers for GAB3 Gene
This gene is a member of the GRB2-associated binding protein gene family. These proteins are scaffolding/docking proteins that are involved in several growth factor and cytokine signaling pathways, and they contain a pleckstrin homology domain, and bind SHP2 tyrosine phosphatase and GRB2 adapter protein. The protein encoded by this gene facilitates macrophage differentiation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]
GeneCards Summary for GAB3 Gene
GAB3 (GRB2 Associated Binding Protein 3) is a Protein Coding gene. Among its related pathways are p70S6K Signaling and MAPK Signaling: Mitogen Stimulation Pathway. An important paralog of this gene is GAB2.