V3 here soon-try beta now


Gene Search (GeneCards Home)	\|	GeneCards Guide	\|	User Feedback	\|	Terms of Use	\|	Notice about third-party sites

GAB2 Gene

protein-coding GIFtS: 68

GC11M077603

GRB2-associated binding protein 2
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc , and/or ⁷Ensembl, ⁸miRBase)
About This Section

Aliases
KIAA0571 ^¹, ², ³
pp100 ^³

Descriptions
GRB2-associated binder 2 ^², ³
GRB2-associated binding protein 2 ^²
Growth factor receptor bound protein 2-associated protein 2 ^³

External Ids
HGNC: 14458¹
Entrez Gene: 9846²
UniProtKB: Q9UQC2³
Ensembl: ENSG00000033327⁷

Search outside databases for aliases for GAB2 gene

Previous GC identifers: GC11M080253 GC11M079465 GC11M078149 GC11M077652

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

EntrezGene summary for GAB2:

This gene is a member of the GRB2-associated binding protein (GAB) gene family and is similar to

the GAB1 gene. These proteins contain pleckstrin homology (PH) domain, and bind SHP2 tyrosine

phosphatase and GRB2 adapter protein. They act as adapters for transmitting various signals in

response to stimuli through cytokine and growth factor receptors, and T- and B-cell antigen

receptors. The protein encoded by this gene is the principal activator of phosphatidylinositol-3

kinase in response to activation of the high affinity IgE receptor. Two alternatively spliced

transcripts encoding different isoforms have been described for this gene. [provided by RefSeq]

Gene Wiki entry for GAB2

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
About This Section

Genomic View:

UCSC Golden Path with GeneCards custom track

Transcription factor binding sites upstream to the GAB2 gene

Entrez Gene cytogenetic band: 11q14.1 Ensembl cytogenetic band: 11q14.1 HGNC cytogenetic band: 11q13.4-q13.5

GAB2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 11 GeneLoc Exon Structure

GeneLoc location for GC11M077603: (about GC identifiers)

Start:	77,603,990 bp from pter
End:	77,806,414 bp from pter
Size:	202,425 bases
Orientation:	minus strand

RefSeq DNA sequence:

NC_000011.8 NT_033927.7

(According to ¹UniProtKB, and/or Ensembl, Phosphorylation sites according to ²Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
About This Section

UniProtKB/Swiss-Prot: GAB2_HUMAN, Q9UQC2 (See protein sequence)

Recommended Name: GRB2-associated-binding protein 2

Size: 676 amino acids; 74458 Da

Subunit: Interacts with GRB2, PI-3 kinase and with other SH2-containing proteins

Secondary accessions: A6NEW9 O60317

Alternative splicing: 2 isoforms: Q9UQC2-1 Q9UQC2-2

Post-translational modifications:

Phosphorylated on tyrosine residue(s) by the thrombopoietin receptor (TPOR), stem cell factor

receptor (SCFR), and T-cell and B-cell antigen receptors, gp130, IL-2R and IL-3R¹

Dephosphorylated by PTPN11¹

View phosphorylation sites using PhosphoSite²

REFSEQ proteins (2 alternative transcripts):

NP_036428.1 NP_536739.1

ENSEMBL proteins:

ENSP00000302452 ENSP00000354952 ENSP00000343959

Human Recombinant Proteins

	Browse Drug Discovery Central at Invitrogen for human recombinant proteins
	Browse Purified and Recombinant Proteins at Millipore
	Browse Human Recombinant Proteins at Sigma-Aldrich
	Browse R&D Systems for human recombinant proteins
	Browse recombinant and purified proteins available from Enzo Life Sciences
	Recombinant Proteins from Abcam (GAB2)
	Human Recombinant Proteins from Abnova (GAB2)

OriGene Purified Recombinant Human Protein: GAB2

Antibodies for GAB2:

	Browse Antibodies Central at Invitrogen
	Millipore Mono- and Polyclonal Antibodies for the study of GAB2
	Sigma-Aldrich Antibodies for GAB2
	R&D Systems Antibodies for GAB2
	Cell Signaling Technology (CST) Antibodies for GAB2
	Antibodies from Abcam (GAB2), each with their Abpromise^SM
	Monoclonal and Polyclonal Antibodies from Abnova (GAB2)
	Novus Biologicals Antibodies for GAB2

Assays for GAB2:

	Browse Invitrogen for biochemical assays
	Browse Kits and Assays available from Millipore
	Browse R&D Systems for biochemical assays
	Browse biochemical assays available from Enzo Life Sciences

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

Graphical View of Domain Structure for InterPro Entry Q9UQC2

ProtoNet protein and cluster: Q9UQC2

1 Blocks protein family: IPB001849 Pleckstrin-like

UniProtKB/Swiss-Prot: GAB2_HUMAN, Q9UQC2

Similarity: Belongs to the GAB family

Similarity: Contains 1 PH domain

(According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (GAB2)
		Browse for Gene Knock-down Tools from Millipore
		Browse Abnova for Chimera RNAi Products

OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 2): NM_080491

Applied Biosystems Silencer® siRNAs for GAB2

Sigma-Aldrich siRNA for GAB2

Sigma-Aldrich shRNA for GAB2

Explore Sigma-Aldrich super-pooled esiRNAs

Clones:		Browse Clone Ranger at Invitrogen for clones
		Browse Clones for the Expression of Recombinant Proteins Available from Millipore

OriGene GFP tagged cDNA clones in CMV expression vector (see all 2): NM_012296
Myc/DDK tagged cDNA clones in CMV expression vector (see all 2): NM_012296
untagged cDNA clones in CMV expression vector (see all 2): NM_012296

Primers:

Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers

OriGene genome-wide validated SYBR primer pairs: NM_080491

6 MGI mutant phenotypes (inferred from 4 alleles) (MGI details for Gab2):

	hematopoietic system	immune system	life span-post-weaning/aging	muscle
skeleton

(Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to ¹UniProtKB, ²MINT, and/or ³STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

5/9 Sigma-Aldrich "Your Favorite Gene" Pathways for GAB2 (Your Favorite Gene powered by Ingenuity) (see all 9 )

Molecular Mechanisms of Cancer
B Cell Receptor Signaling
iCOS-iCOSL Signaling in T Helper Cells
Thrombopoietin Signaling
Chronic Myeloid Leukemia Signaling

GeneDecks GAB2 for the pathways selected above

About GeneDecksing

Gene Network Central^TM Interacting Genes and Proteins Network for GAB2

5/88 Interacting proteins for GAB2 (ENSP00000343959³ Q9UQC2²) via UniProtKB, MINT, and/or STRING (see all 88 )

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
SHC1	P29353²	STRING (score=.998) MINT-14688 MINT-14689
GRB2	P62993²	STRING (score=.999) MINT-58401
MAPK3	P27361²	STRING (score=.989) MINT-56633
PIK3R1	P27986²	STRING (score=.999) MINT-68496
PTPN11	ENSP00000340944³	STRING (score=.999)

About this table

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
About This Section

Browse drugs & compounds from Enzo Life Sciences

Browse Small Molecules at Sigma-Aldrich

Browse Tocris compounds for GAB2
6 Novoseek chemical compound relationships for GAB2 gene

Compound	Score	Articles	PubMed IDs for Articles with Shared Sentences (# sentences)
pp 100	80.30	6	12636255 (4), 7683492 (1)
phosphatidylinositol	68.85	7	15143164 (1), 16371368 (1), 11489921 (1), 10455108 (1) (see all 6)
tyrosine	68.71	72	15356145 (5), 11340297 (4), 12636255 (3), 15170389 (3) (see all 29)
phosphoinositide	26.95	3	14530346 (1), 18697750 (1), 11335710 (1)
threonine	1.21	4	15356145 (1), 11782427 (1)
lipid	0.00	3	16456001 (2)

About this table

(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Invitrogen, Millipore, and/or Abnova,
siRNAs from Applied Biosystems, Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene,
Tagged/untagged cDNA clones from OriGene,
Expression Assays from Applied Biosystems)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (GAB2)
		Browse for Gene Knock-down Tools from Millipore
		Browse Abnova for Chimera RNAi Products

OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 2): NM_080491

Sigma-Aldrich siRNA for GAB2

Sigma-Aldrich shRNA for GAB2

Explore Sigma-Aldrich super-pooled esiRNAs

Applied Biosystems Silencer® siRNAs:

NM_012296 NM_080491

REFSEQ mRNAs for GAB2 gene (2 alternative transcripts):

NM_012296.2 NM_080491.1

Applied Biosystems TaqMan ® Gene Expression Assays:

NM_012296 NM_080491

               OriGene GFP tagged cDNA clones in CMV expression vector (see all 2): NM_012296
                                 Myc/DDK tagged cDNA clones in CMV expression vector (see all 2): NM_012296
                                 untagged cDNA clones in CMV expression vector (see all 2): NM_012296

Additional cDNA sequence:

AB011143.1 AB018413.1 BC131711.1 BC152459.1 CR600944.1

8 DOTS entries:

DT.95167054 DT.100744553 DT.100721545 DT.75190436 DT.120751567 DT.91765984 DT.120751557 DT.91684213

24/125 AceView cDNA sequences (see all 125 ):

BQ071161 AB011143 BU849697 CA436196 BE855609 BI089482 BQ279179 CD245149

BQ683030 AB018413 BF988854 BQ683715 CA389434 BX097734 BQ926998 BU173648

BU150847 BQ070464 NM_080491 CR600944 BE313810 BM905073 BQ186653 NM_012296

highest scoring ESTs for GAB2:

AB011143 AB018413 BQ027669 AA157331 AA157428 AA294852 AA296718 AA342003 AA369150 AA369151

Unigene Cluster for GAB2:

GRB2-associated binding protein 2

Hs.429434 [show with all ESTs]

Unigene Representative Sequence: BC152459

GeneLoc Exon Structure

5/7 Alternative Splicing Database (ASD) splice patterns (SP) for GAB2 (see all 7 )

ExUns:	1	^	2a	·	2b	^	3	^	4a	·	4b	^	5a	·	5b	·	5c	·	5d	^	6	^	7a	·	7b	^	8	^	9	^	10a	·	10b	^	11a	·	11b	^	12	^	13	^	14
SP1:
SP2:
SP3:
SP4:																					-
SP5:			-		-		-

About this scheme

ECgene alternative splicing isoforms for GAB2

3 Ensembl transcripts including schematic representations:

ENST00000304401 ENST00000361507 ENST00000340149

(Experimental results according to ¹GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to ²GeneAnnot , ³GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Expression Assays from Applied Biosystems )
About This Section

GAB2 expression in normal and diseased human tissues

Applied Biosystems TaqMan ® Gene Expression Assays for GAB2

¹ / ² / ³

3 probe-sets matching GAB2 gene

Affymetrix probe-set	Array	# genes	Sensitivity	Specificity	Correlation	Length	Gb_Accession	Consensus	Uniqueness	Score	Rank
Affymetrix probe-set	Array	GeneAnnot data			GeneNote data		GeneTide data
35253_at²^{, 3}	U95-A	1	0.62	1.00	1.00	1.00	AB011143	0.80	1.00	0.91	1
203853_s_at²^{, 3}	U133-A	1	1.00	1.00	--	--	NM_012296	0.60	1.00	0.82	1
203853_s_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--

GeneDecks GAB2 for binary patterns associated with the probe-sets selected above

About GeneDecksing

About this table

Data from

(Publications) and GNF BioGPS
About these images
About these images

CGAP SAGE TAG: GTACAGGCTT

SOURCE GeneReport for Unigene cluster: Hs.429434
Expression variation in blood from EXPOLDB for GAB2

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD and/or ⁵MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
About This Section

Orthologs for GAB2 gene from 5/6 species (see all 6 )

Organism	Gene	Locus	Description	Human Similarity	NCBI accessions
dog (Canis familiaris)	GAB2¹	--	GRB2-associated binding protein 2	90.91(n) 94.49(a)	485167 XM_542285.2 XP_542285.2
cow (Bos taurus)	GAB2¹	--	GRB2-associated binding protein 2	88.22(n) 92.93(a)	529346 XM_607792.2 XP_607792.2
rat (Rattus norvegicus)	Gab2¹	--	GRB2-associated binding protein 2	88.07(n) 93.5(a)	84477 NM_053417.1 NP_445869.1
mouse (Mus musculus)	Gab2^{1, 5}	7⁵	growth factor receptor bound protein 2-associated protein more^{1, 5}	89.07(n)¹ 93.96(a)¹	14389¹ NM_010248.1¹ NP_034378.1¹ AB018414⁵ AF104244⁵ (see all 12)
chicken (Gallus gallus)	GAB2¹	--	GRB2-associated binding protein 2	74.8(n) 79.17(a)	419027 XM_001234548.1 XP_001234549.1

About this table Species with no ortholog for GAB2

ENSEMBL Gene Tree for GAB2

(Paralogs according to ¹HomoloGene
and ²Ensembl, Pseudogenes according to ³Pseudogene.org)
About This Section

Paralogs for GAB2 gene

GAB1² GAB3² GAB4²

(According to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
About This Section

10/669 NCBI SNPs in GAB2 are shown (see all 669 )
(Click for Applied Biosystems TaqMan ® Genotyping Assay) (see all 344)

AB	SNP ID	Valid	Chr 11 pos	Sequence	Recs	AA Chg	Type	More	Recs	Pop	Total sample	More
AB	Genomic Data				Transcription Data				Allele Frequencies
				--	--	--		--	--			--
	rs2912^1,2	A,C,F,H	77603940(-)	`GAACCC/TGTTCT`	2	--	ng5¹		14	NS MN NA EU EA WA	1134
	rs866901^1,2	A,C,F,H	77603957(-)	`TGAGGG/AGCTTG`	2	--	ng5¹		4	EU EA WA	388
	rs1485483^1,2	A,C,F,H	77607786(-)	`TGATCA/GAGGCA`	2	--	ut3¹		6	MN EU EA WA	764
	rs3740677^1,2	A,C,F,H	77605684(+)	`CTTTTG/TTTCCC`	2	--	ut3¹ ese³		14	EA NA EU WA	2714
	rs1046780^1,2	A,C,F,H	77604417(-)	`CACAAT/CGGGGT`	2	--	ut3¹ ese³		5	MN EU EA WA	602
	rs2511162^1,2	A,C,F,H	77604749(+)	`ACCCCA/GATCCC`	2	--	ut3¹		4	EU EA WA	370
	rs2450135^1,2	C,F,H	77605643(+)	`CCCCTG/ACACTT`	2	--	ut3¹		11	EA NA EU WA	2290
	rs2279374^1,2	C,F,H	77615335(-)	`CACTCC/TTGGGG`	2	P/L	mis¹ ese³		9	EA EU WA	2322
	rs481240^1,2	F,H	77606794(-)	`AGCAAG/CTGGGG`	2	--	ut3¹		6	EA NA EU WA	452
	rs2848984^1,2	C,H	77610375(+)	`CCATAG/TGGACA`	2	P/H	mis¹ ese³		4	EU EA WA	420

About this table

HapMap Linkage Disequilibrium images for GAB2 (up to first 250kb)

(in which this Gene is Involved, According to OMIM, UniProtKB, Novoseek, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
About This Section

OMIM: 606203

7 Novoseek disease relationships for GAB2 gene

Disease	Score	Articles	PubMed IDs for Articles with Shared Sentences (# sentences)
myeloid leukemia chronic	38.50	2	18235045 (1), 16278304 (1)
breast cancer	15.72	18	12140767 (4), 17558859 (2), 17998934 (2), 17310989 (1) (see all 6)
cancer	0.00	3	17310989 (1), 17558859 (1), 19342374 (1)
tumors	0.00	15	19342374 (3), 16369543 (2), 11340297 (2), 17310989 (1) (see all 5)
lymphoma	0.00	1	14530346 (1)
metastasis	0.00	8	17310989 (4), 17558859 (1), 19342374 (1)
virus infection	0.00	1	17353274 (1)

About this table

Human Gene Mutation Database: GAB2
Human Genome Epidemiology Navigator: GAB2 (7 documents)

(Possibly Related Articles in Doctor's Guide)
About This Section

(in PubMed. Associations of this gene to articles via ¹Novoseek, ²HGNC, ³Entrez Gene, ⁴UniProtKB/Swiss-Prot, ⁵UniProtKB/TrEMBL, ⁶GAD, and/or ⁷PharmGKB)
About This Section

10/108 PubMed articles for GAB2 gene (see all 108 ):

Gab-family adapter proteins act downstream of cytokine and growth factor receptors and T- and B-cell antigen receptors. (PubMed id 10068651)^{1, 2, 3, 4} Nishida K....Hirano T. (1999)
Gab2, a new pleckstrin homology domain-containing adapter protein, acts to uncouple signaling from ERK kinase to Elk-1. (PubMed id 10391903)^{1, 2, 3} Zhao C....Feng G.S. (1999)
Profiling of tyrosine phosphorylation pathways in human cells using mass spectrometry. (PubMed id 12522270)^{3, 4} Salomon A.R.... Peters E.C. (2003)
Prediction of the coding sequences of unidentified human genes. IX. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro. (PubMed id 9628581)^{3, 4} Nagase T....Ohara O. (1998)
Phosphorylation of Grb2-associated binder 2 on serine 623 by ERK MAPK regulates its association with the phosphatase SHP-2 and decreases STAT5 activation. (PubMed id 15356145)^{1, 3} Arnaud M....Bertoglio J. (2004)
Gab2 and Src co-operate in human mammary epithelial cells to promote growth factor independence and disruption of acinar morphogenesis. (PubMed id 17998934)^{1, 3} Bennett H.L....Daly R.J. (2008)
Participation of both Gab1 and Gab2 in the activation of the ERK/MAPK pathway by epidermal growth factor. (PubMed id 15952937)^{1, 3} Meng S....Wu J. (2005)
PKB-mediated negative feedback tightly regulates mitogenic signalling via Gab2. (PubMed id 11782427)^{1, 3} Lynch D.K. and Daly R.J. (2002)
A role for the scaffolding adapter GAB2 in breast cancer. (PubMed id 16369543)^{1, 3} Bentires-Alj M....Gu H. (2006)
Regulation of the Erk2-Elk1 signaling pathway and megakaryocytic differentiation of Bcr-Abl(+) K562 leukemic cells by Gab2. (PubMed id 11830491)^{1, 3} Dorsey J.F....Wu J. (2002)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
About This Section

Entrez Gene: 9846	HGNC: 14458	AceView: GAB2	Ensembl:ENSG00000033327	euGenes: HUgn9846
ECgene: GAB2	H-InvDB: GAB2

(According to HUGE)
About This Section

HUGE: KIAA0571

(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
ATLAS Chromosomes in Cancer entry for GAB2	Genetics and Cytogenetics in Oncology and Haematology

Licensable Technologies for GAB2
(Available from WIS Yeda, Salk, Tufts)

About This Section

(Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
Enzo Life Sciences, and/or Tocris Bioscience)
About This Section

Products for GAB2:

TaqMan ® Gene Expression Assays

TaqMan ® Genotyping Assays

Free SNP selection tool

Invitrogen iPath Pathways	Invitrogen BLOCK-iT™ RNAi
Invitrogen Antibodies	Invitrogen Assays
Invitrogen Clones	Invitrogen Q-PCR Products
Invitrogen Human Recombinant Kinases	Invitrogen Custom Antibody and Peptide Service
Invitrogen Proteins / Assays / Screening Services	Search Invitrogen catalog for GAB2-related products

	Millipore Custom Antibody & Bulk Services
	Millipore Preclinical / Clinical Development Services
	Millipore Immunoassay Services
	Millipore Target Screening & Profiling Services

	Predesigned and custom siRNAs for GAB2		Antibodies for GAB2
	Explore super-pooled esiRNAs		Browse proteins at Sigma-Aldrich
	Lentivirus-delivered shRNAs for GAB2		Browse small molecules at Sigma-Aldrich
	"Your Favorite Gene" Pathways		feedback

	Antibodies		Primer Pairs
	Cell Culture Products		ELISAs
	Flow Cytometry Kits		Protease Activity Assays & Reagents
	Cell Selection/Detection Kits & Reagents		ELISA/Assay Development Kits & Reagents
	Multiplex/Array Assay Kits & Reagents		ELISpot Kits & Development Modules
	Recombinant & Natural Proteins

	Recombinant Proteins (GAB2)
	Antibodies (GAB2)
	Search for Chimera RNAi
	Custom Service for Mouse Mab
	Custom Service for Rabbit Pab from Full-length Protein

Antibodies & Assays for GAB2

	Recombinant Proteins (GAB2)
	Antibodies (GAB2)

	Tagged/untagged cDNA clones
	Validated SYBR primer pairs
	Purified proteins from HEK293T cells
	Western blot validated antibodies
	shRNA in GFP-retroviral vector

Search Tocris compounds for GAB2

Search www.enzolifesicences.com for proteins, assays, substrates, inhibitors & antibodies

Antibodies for GAB2

GeneCards Homepage - Last full update: 2 Jul 2009 Incremental update: 13 Oct 2009

Random Gene From GIFtS :

about GIFtS

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Developed at the Crown Human Genome Center & Weizmann Institute of Science

The GeneCards Human Gene Database: Copyright © 1996-2009, Weizmann Institute of Science. All Rights Reserved.
GAB2 Gene at Home site.
Version 2.41.1
server5.xennexinc.com

GAB2 Gene

protein-coding GIFtS: 68

Aliases &
Descriptions
for GAB2

Summaries
for GAB2

Genomic Location
for GAB2

Proteins
for GAB2

Protein Domains/
Families
for GAB2

Gene Function
for GAB2

Pathways & Interactions
for GAB2

Drugs & Compounds
for GAB2

Transcripts
for GAB2

Expression
for GAB2

Orthologs
for GAB2

Paralogs
for GAB2

SNPs/Variants
for GAB2

Disorders & Mutations
for GAB2

Medical News
for GAB2

Publications
for GAB2

Search for GAB2

Genome Databases showing GAB2

Other Databases showing GAB2

Specialized Databases showing GAB2

Licensable Technologies
for GAB2

Services
for GAB2

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

GAB2 Gene

protein-coding GIFtS: 68

Aliases & Descriptionsfor GAB2

Summariesfor GAB2

Genomic Locationfor GAB2

Proteinsfor GAB2

Protein Domains/Familiesfor GAB2

Gene Functionfor GAB2

Pathways & Interactionsfor GAB2

Drugs & Compoundsfor GAB2

Transcriptsfor GAB2

Expression for GAB2

Orthologsfor GAB2

Paralogsfor GAB2

SNPs/Variantsfor GAB2

Disorders & Mutationsfor GAB2

Medical Newsfor GAB2

Publicationsfor GAB2

Search for GAB2

Genome Databases showing GAB2

Other Databases showing GAB2

Specialized Databases showing GAB2

Licensable Technologiesfor GAB2

Servicesfor GAB2

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Aliases &
Descriptions
for GAB2

Summaries
for GAB2

Genomic Location
for GAB2

Proteins
for GAB2

Protein Domains/
Families
for GAB2

Gene Function
for GAB2

Pathways & Interactions
for GAB2

Drugs & Compounds
for GAB2

Transcripts
for GAB2

Expression
for GAB2

Orthologs
for GAB2

Paralogs
for GAB2

SNPs/Variants
for GAB2

Disorders & Mutations
for GAB2

Medical News
for GAB2

Publications
for GAB2

Licensable Technologies
for GAB2

Services
for GAB2