V3 here soon-try beta now


Gene Search (GeneCards Home)	\|	GeneCards Guide	\|	User Feedback	\|	Terms of Use	\|	Notice about third-party sites

G6PC3 Gene

protein-coding GIFtS: 50

GC17P039503

glucose 6 phosphatase, catalytic, 3
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc , and/or ⁷Ensembl, ⁸miRBase)
About This Section

Aliases
EC 3.1.3.9 ^³
G6Pase-beta ^², ³
SCN4 ^², ⁵
UGRP ^¹, ², ³, ⁵

Descriptions
G-6-Pase 3 ^³
G6Pase 3 ^³
Glucose-6-phosphatase beta ^³
Ubiquitous glucose-6-phosphatase catalytic subunit-related protein ^³
glucose 6 phosphatase, catalytic, 3 ^²
glucose-6-phosphatase catalytic subunit 3 ^²
ubiquitously expressed G6Pase catalytic subunit-related protein ^²

External Ids
HGNC: 24861¹
Entrez Gene: 92579²
UniProtKB: Q9BUM1³
Ensembl: ENSG00000141349⁷

Search outside databases for aliases for G6PC3 gene

Previous GC identifer: GC17P042623

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

EntrezGene summary for G6PC3:

Glucose-6-phosphatase (G6Pase) is located in the endoplasmic reticulum (ER) and catalyzes

hydrolysis of G6P to glucose and phosphate, the last step of the gluconeogenic and glycogenolytic

pathways. G6PC3 is a ubiquitously expressed G6Pase catalytic subunit (Martin et al., 2002 [PubMed

12370122]; Guionie et al., 2003 [PubMed 12965222]).[supplied by OMIM]

UniProtKB/Swiss-Prot: G6PC3_HUMAN, Q9BUM1

Function: Hydrolyzes glucose-6-phosphate to glucose in the endoplasmic reticulum. May form with the

glucose-6-phosphate transporter (SLC37A4/G6PT) a ubiquitously expressed complex responsible for

glucose production through glycogenolysis and gluconeogenesis. Probably required for normal

neutrophil function

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
About This Section

Genomic View:

UCSC Golden Path with GeneCards custom track

Transcription factor binding sites upstream to the G6PC3 gene

Entrez Gene cytogenetic band: 17q21.31 Ensembl cytogenetic band: 17q21.31 HGNC cytogenetic band: 17q21.31

G6PC3 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 17 GeneLoc Exon Structure

GeneLoc location for GC17P039503: (about GC identifiers)

Start:	39,503,644 bp from pter
End:	39,509,238 bp from pter
Size:	5,595 bases
Orientation:	plus strand

RefSeq DNA sequence:

NC_000017.9 NT_010783.14

(According to ¹UniProtKB, and/or Ensembl, Phosphorylation sites according to ²Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
About This Section

UniProtKB/Swiss-Prot: G6PC3_HUMAN, Q9BUM1 (See protein sequence)

Recommended Name: Glucose-6-phosphatase 3

Size: 346 amino acids; 38735 Da

Subcellular location: Endoplasmic reticulum membrane; Multi-pass membrane protein

Caution: According to PubMed:12370122 it has no hydrolytic activity

Secondary accessions: Q8WU15

REFSEQ proteins: NP_612396.1

ENSEMBL proteins:

ENSP00000269097

Human Recombinant Proteins

	Browse Drug Discovery Central at Invitrogen for human recombinant proteins
	Browse Purified and Recombinant Proteins at Millipore
	Browse Human Recombinant Proteins at Sigma-Aldrich
	Browse R&D Systems for human recombinant proteins
	Browse recombinant and purified proteins available from Enzo Life Sciences
	Browse Abcam for Recombinant Proteins
	Human Recombinant Proteins from Abnova (G6PC3)

Browse Origene for full length recombinant human proteins expressed in human HEK293 cells

4 Gene Ontology (GO) cellular component terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005783	endoplasmic reticulum	IEA	--
GO:0005789	endoplasmic reticulum membrane	IEA	--
GO:0016020	membrane	IEA	--
GO:0016021	integral to membrane	IEA	--

About this table

Antibodies for G6PC3:

	Browse Antibodies Central at Invitrogen
	Browse Millipore's Extensive Line of Mono- and Polyclonal Antibodies
	Browse Antibodies at Sigma-Aldrich
	Browse R&D Systems for Antibodies
	Search for antibodies at Abcam and the World's Antibody Gateway (free search engine of over 150 antibody companies)
	Browse Abnova for Monoclonal and Polyclonal Antibodies
	Search Novus for antibodies for G6PC3

Assays for G6PC3:

	Browse Invitrogen for biochemical assays
	Browse Kits and Assays available from Millipore
	Browse R&D Systems for biochemical assays
	Browse biochemical assays available from Enzo Life Sciences

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

Graphical View of Domain Structure for InterPro Entry Q9BUM1

ProtoNet protein and cluster: Q9BUM1

1 Blocks protein family: IPB000326 PA-phosphatase related phosphoesterase

UniProtKB/Swiss-Prot: G6PC3_HUMAN, Q9BUM1

Similarity: Belongs to the glucose-6-phosphatase family

(According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (G6PC3)
		Browse for Gene Knock-down Tools from Millipore
		Browse Abnova for Chimera RNAi Products

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_138387

Applied Biosystems Silencer® siRNAs for G6PC3

Sigma-Aldrich siRNA and siRNA Panels for G6PC3

Sigma-Aldrich shRNA for G6PC3

Explore Sigma-Aldrich super-pooled esiRNAs

Clones:		Invitrogen Clones for G6PC3
		Browse Clones for the Expression of Recombinant Proteins Available from Millipore

OriGene GFP tagged cDNA clone in CMV expression vector: NM_138387
Myc/DDK tagged cDNA clone in CMV expression vector: NM_138387
untagged cDNA clones in CMV expression vector (see all 3): AK091417

Primers:

Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers

OriGene genome-wide validated SYBR primer pairs: NM_138387

UniProtKB/Swiss-Prot: G6PC3_HUMAN, Q9BUM1

Function: Hydrolyzes glucose-6-phosphate to glucose in the endoplasmic reticulum. May form with the

glucose-6-phosphate transporter (SLC37A4/G6PT) a ubiquitously expressed complex responsible for

glucose production through glycogenolysis and gluconeogenesis. Probably required for normal

neutrophil function

Catalytic activity: D-glucose 6-phosphate + H(2)O = D-glucose + phosphate

Enzyme regulation: Inhibited by vanadate

Biophysicochemical properties: Kinetic parameters: KM=1.0 mM for glucose-6-phosphate (at pH 5.5.);

KM=2.0 mM for glucose-6-phosphate (at pH 6.5.); Note=8 times less active compared to G6PC under

the same experimental conditions;

Enzyme Number (IUBMB): EC 3.1.3.9

7 MGI mutant phenotypes (inferred from 3 alleles) (MGI details for G6pc3):

digestive/alimentary	endocrine/exocrine gland	growth/size	hematopoietic system	homeostasis/metabolism
immune system	life span-post-weaning/aging

2 Gene Ontology (GO) molecular function terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0004346	glucose-6-phosphatase activity	IEA	--
GO:0016787	hydrolase activity	IEA	--

About this table

(Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to ¹UniProtKB, ²MINT, and/or ³STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

5 Sigma-Aldrich "Your Favorite Gene" Pathways for G6PC3 (Your Favorite Gene powered by Ingenuity)

FXR/RXR Activation
Estrogen Receptor Signaling
Starch and Sucrose Metabolism
Glycolysis/Gluconeogenesis
Galactose Metabolism

GeneDecks G6PC3 for the pathways selected above

About GeneDecksing

UniProtKB/Swiss-Prot: G6PC3_HUMAN, Q9BUM1

Pathway: Carbohydrate biosynthesis; gluconeogenesis

3 Interacting proteins for G6PC3 (ENSP00000269097³) via UniProtKB, MINT, and/or STRING

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
ENSG00000206394	ENSP00000372897³	STRING (score=.895)
SLC37A4	ENSP00000339048³	STRING (score=.843)
SCGB3A2	ENSP00000296694³	STRING (score=.734)

About this table

2 Gene Ontology (GO) biological process terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0006094	gluconeogenesis	IEA	--
GO:0015760	glucose-6-phosphate transport	IEA	--

About this table

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
About This Section

Browse drugs & compounds from Enzo Life Sciences

Browse Small Molecules at Sigma-Aldrich

Browse Tocris compounds for G6PC3

(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Invitrogen, Millipore, and/or Abnova,
siRNAs from Applied Biosystems, Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene,
Tagged/untagged cDNA clones from OriGene,
Expression Assays from Applied Biosystems)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (G6PC3)
		Browse for Gene Knock-down Tools from Millipore
		Browse Abnova for Chimera RNAi Products

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_138387

Sigma-Aldrich siRNA and siRNA Panels for G6PC3

Sigma-Aldrich shRNA for G6PC3

Explore Sigma-Aldrich super-pooled esiRNAs

Applied Biosystems Silencer® siRNAs:

NM_138387

REFSEQ mRNAs for G6PC3 gene:

NM_138387.2

Applied Biosystems TaqMan ® Gene Expression Assays:

NM_138387

              OriGene GFP tagged cDNA clone in CMV expression vector: NM_138387
                                 Myc/DDK tagged cDNA clone in CMV expression vector: NM_138387
                                 untagged cDNA clones in CMV expression vector (see all 3): AK091417

Additional cDNA sequence:

AK091417.1 BC002494.2 BC021574.1 BC062596.1 CR590248.1 CR590923.1 CR591259.1 CR595523.1

CR597546.1 CR598130.1 CR598996.1 CR601615.1 CR605360.1 CR607017.1 CR607320.1 CR608514.1

CR608544.1 CR609384.1 CR613351.1 CR615676.1 CR617855.1 CR619652.1 CR622205.1 CR623861.1

CR624359.1 CR625794.1

15 DOTS entries:

DT.214766 DT.100817498 DT.100817495 DT.95245069 DT.100817504 DT.100817486 DT.100817488 DT.100817499

DT.120906481 DT.99939549 DT.100817490 DT.92046312 DT.92452291 DT.95245003 DT.99926739

24/365 AceView cDNA sequences (see all 365 ):

BQ919298 CR607017 CA454913 BF344330 AI670976 BC002494 AL526455 BQ946868

BG419790 BU151257 CR591259 CA488619 AI283242 BM042047 CA454159 AI274000

BM851686 CR607320 CR608514 BE397771 AI540614 CR613351 CR601615 BU557413

highest scoring ESTs for G6PC3:

AI669655 AA232553 AA292746 AA293719 AA296469 AA318820 AA364430 AA427485 AA477724 AA477725

Unigene Cluster for G6PC3:

Glucose 6 phosphatase, catalytic, 3

Hs.294005 [show with all ESTs]

Unigene Representative Sequence: AK091417

GeneLoc Exon Structure

5/9 Alternative Splicing Database (ASD) splice patterns (SP) for G6PC3 (see all 9 )

ExUns:	1a	·	1b	·	1c	·	1d	^	2a	·	2b	^	3	^	4	^	5	^	6a	·	6b	·	6c	^	7a	·	7b	·	7c	·	7d	·	7e
SP1:							-												-
SP2:							-		-		-								-
SP3:									-		-								-
SP4:							-		-		-						-		-
SP5:							-		-		-								-

About this scheme

ECgene alternative splicing isoforms for G6PC3

1 Ensembl transcript including schematic representation:

ENST00000269097

(Experimental results according to ¹GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to ²GeneAnnot , ³GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Expression Assays from Applied Biosystems )
About This Section

G6PC3 expression in normal and diseased human tissues

Applied Biosystems TaqMan ® Gene Expression Assays for G6PC3

¹ / ² / ³

5 probe-sets matching G6PC3 gene

Affymetrix probe-set	Array	# genes	Sensitivity	Specificity	Correlation	Length	Gb_Accession	Consensus	Uniqueness	Score	Rank
Affymetrix probe-set	Array	GeneAnnot data			GeneNote data		GeneTide data
44654_at²^{, 3}	U133-B	1	1.00	1.00	1.00	1.00	AI669655	1.00	1.00	1.00	1
221759_at²^{, 3}	U133-A	1	1.00	1.00	--	--	AL583123	0.80	1.00	0.91	1
44654_at²^{, 3}	U133-A	1	1.00	1.00	--	--	AI669655	1.00	1.00	1.00	1
221759_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--
44654_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--

About this table

Data from

(Publications) and GNF BioGPS
About these images
About these images

CGAP SAGE TAG: TTCAGTGCCC

SOURCE GeneReport for Unigene cluster: Hs.294005
UniProtKB/Swiss-Prot: G6PC3_HUMAN, Q9BUM1
Tissue specificity: Ubiquitously expressed. Highly expressed in skeletal muscle, at intermediate
levels in heart, brain, placenta, kidney, colon, thymus, spleen and pancreas. Also detected in
testis, prostate, ovary, liver, lung, small intestine and peripheral blood lymphocytes

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD and/or ⁵MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
About This Section

Orthologs for G6PC3 gene from 5/9 species (see all 9 )

Organism	Gene	Locus	Description	Human Similarity	NCBI accessions
dog (Canis familiaris)	G6PC3¹	--	glucose 6 phosphatase, catalytic, 3	90.37(n) 91.33(a)	490942 XM_548065.2 XP_548065.2
cow (Bos taurus)	G6PC3¹	--	glucose 6 phosphatase, catalytic, 3	91.43(n) 91.91(a)	369023 NM_183364.2 NP_899208.2
rat (Rattus norvegicus)	G6pc3¹	--	glucose 6 phosphatase, catalytic, 3	84.59(n) 81.79(a)	303565 NM_176077.3 NP_788266.2
mouse (Mus musculus)	G6pc3^{1, 5}	11⁵	glucose 6 phosphatase, catalytic, 3^{1, 5}	85.45(n)¹ 84.1(a)¹	68401¹ NM_175935.3¹ NP_787949.2¹ AK002966⁵ AK165395⁵ (see all 16)
zebrafish (Danio rerio)	zgc:158425¹	--	zgc:158425	53.25(n) 46.85(a)	790919 NM_001080066.1 NP_001073535.1

About this table Species with no ortholog for G6PC3

ENSEMBL Gene Tree for G6PC3

(Paralogs according to ¹HomoloGene
and ²Ensembl, Pseudogenes according to ³Pseudogene.org)
About This Section

Paralogs for G6PC3 gene

G6PC2² G6PC²

(According to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
About This Section

10/53 NCBI SNPs in G6PC3 are shown (see all 53 )
(Click for Applied Biosystems TaqMan ® Genotyping Assay) (see all 46)

AB	SNP ID	Valid	Chr 17 pos	Sequence	Recs	AA Chg	Type	More	Recs	Allele freq	Pop	Total sample	More
AB	Genomic Data				Transcription Data				Allele Frequencies
				--	--	--		--	--				--
	rs34406052^1,2	C,F	39508315(-)	`AGAGGG/ATCCAA`	1	I/T	mis¹		5		NA EU EA WA	498
	rs179266^1,2	C,H	39503216(-)	`CCTTTC/TTAATT`	1	--	ng5¹ trp³		4		EU EA WA	418
	rs228758^1,2	F,H	39503731(-)	`CCAGCG/AGTCAC`	1	--	ut5¹ ese³		4		EU EA WA	418
	rs1046770^1,2	A,F	39509088(+)	`CCAAAG/CATGGG`	1	--	ut3¹		1		MN	184
--	rs2631291^1,2	C	39501921(-)	`agagaC/Tggggt`	1	--	ng5¹		0	--	--	--	--
	rs3815076^1,2	C,F,H	39507629(-)	`AGGGCC/TGTCAT`	1	T/T	syn¹ ese³		5		EU EA WA NA	484
--	rs228759^1,2	A,C	39505284(-)	`attgcA/Gccact`	1	--	int¹		0	--	--	--	--
	rs4793075^1,2	H	39504747(+)	`aagcaC/TtgCTT`	1	--	int¹		4		EU EA WA	418
--	rs12449799^1,2	C	39505810(+)	`acaggC/Tgtgag`	1	--	int¹		0	--	--	--	--
	rs1611957^1,2	H	39504832(-)	`TGTCCC/GTGGGA`	1	--	int¹		4		EU EA WA	400

About this table

HapMap Linkage Disequilibrium images for G6PC3 (up to first 250kb)

(in which this Gene is Involved, According to OMIM, UniProtKB, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
About This Section

OMIM: 611045 disorders: 612541

UniProtKB/Swiss-Prot: G6PC3_HUMAN, Q9BUM1

Defects in G6PC3 are the cause of autosomal recessive severe congenital neutropenia type 4

(SCN4) [MIM:612541]. Autosomal recessive SCN constitutes a primary immunodeficiency syndrome

associated with increased apoptosis in myeloid cells. Individuals show a paucity of mature

neutrophils in peripheral blood and bone marrow and develop life-threatening bacterial infections.

SCN4 is a severe congenital neutropenia syndrome associated with cardiac and urogenital

malformations

Human Gene Mutation Database: G6PC3

(Possibly Related Articles in Doctor's Guide)
About This Section

(in PubMed. Associations of this gene to articles via ¹Novoseek, ²HGNC, ³Entrez Gene, ⁴UniProtKB/Swiss-Prot, ⁵UniProtKB/TrEMBL, ⁶GAD, and/or ⁷PharmGKB)
About This Section

10/11 PubMed articles for G6PC3 gene (see all 11 ):

Identification and characterization of a human cDNA and gene encoding a ubiquitously expressed glucose-6-phosphatase catalytic subunit-related protein. (PubMed id 12370122)^{1, 2, 3, 4} Martin C.C....O'Brien R.M. (2002)
Identification and characterisation of a new human glucose-6-phosphatase isoform. (PubMed id 12965222)^{2, 3, 4} Guionie O....Burchell A. (2003)
A syndrome with congenital neutropenia and mutations in G6PC3. (PubMed id 19118303)^{3, 4} Boztug K.... Klein C. (2009)
Histidine 167 is the phosphate acceptor in glucose-6-phosphatase-beta forming a phosphohistidine enzyme intermediate during catalysis. (PubMed id 14718531)⁴ Ghosh A.... Chou J.Y. (2004)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)⁴ Gerhard D.S....Malek J. (2004)
Identification and characterization of a cDNA and the gene encoding the mouse ubiquitously expressed glucose-6-phosphatase catalytic subunit-related protein. (PubMed id 14765991)⁴ Boustead J.N.... O'Brien R.M. (2004)
A glucose-6-phosphate hydrolase, widely expressed outside the liver, can explain age-dependent resolution of hypoglycemia in glycogen storage disease type Ia. (PubMed id 13129915)⁴ Shieh J.J....Chou J.Y. (2003)
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)³ Strausberg R.L....Marra M.A. (2002)
Hepatitis C virus core protein interacts with 14-3-3 protein and activates the kinase Raf-1. (PubMed id )⁴ Aoki H.... Hino O. (2000)
Deletion of the gene encoding the ubiquitously expressed glucose-6-phosphatase catalytic subunit-related protein (UGRP)/glucose-6-phosphatase catalytic subunit-beta results in lowered plasma cholesterol and elevated glucagon. (PubMed id 17023421)¹ Wang Y....O'Brien R.M. (2006)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
About This Section

Entrez Gene: 92579	HGNC: 24861	AceView: G6PC3	Ensembl:ENSG00000141349	euGenes: HUgn92579
ECgene: G6PC3	H-InvDB: G6PC3

(According to HUGE)
About This Section

(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Licensable Technologies for G6PC3
(Available from WIS Yeda, Salk, Tufts)

About This Section

(Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
Enzo Life Sciences, and/or Tocris Bioscience)
About This Section

Products for G6PC3:

TaqMan ® Gene Expression Assays

TaqMan ® Genotyping Assays

Free SNP selection tool

Invitrogen iPath Pathways	Invitrogen BLOCK-iT™ RNAi
Invitrogen Antibodies	Invitrogen Assays
Invitrogen Clones	Invitrogen Q-PCR Products
Invitrogen Human Recombinant Kinases	Invitrogen Custom Antibody and Peptide Service
Invitrogen Proteins / Assays / Screening Services	Search Invitrogen catalog for G6PC3-related products

	Millipore Custom Antibody & Bulk Services
	Millipore Preclinical / Clinical Development Services
	Millipore Immunoassay Services
	Millipore Target Screening & Profiling Services

	Predesigned and custom siRNAs for G6PC3		Browse antibodies at Sigma-Aldrich
	Explore super-pooled esiRNAs		Browse proteins at Sigma-Aldrich
	Lentivirus-delivered shRNAs for G6PC3		Browse small molecules at Sigma-Aldrich
	"Your Favorite Gene" Pathways		feedback

	Antibodies		Primer Pairs
	Cell Culture Products		ELISAs
	Flow Cytometry Kits		Protease Activity Assays & Reagents
	Cell Selection/Detection Kits & Reagents		ELISA/Assay Development Kits & Reagents
	Multiplex/Array Assay Kits & Reagents		ELISpot Kits & Development Modules
	Recombinant & Natural Proteins

	Recombinant Proteins (G6PC3)
	Search for Antibodies
	Search for Chimera RNAi
	Custom Service for Mouse Mab
	Custom Service for Rabbit Pab from Full-length Protein

Search for Antibodies & Assays

	Search for Recombinant Proteins
	Search for Antibodies

Search OriGene for G6PC3

Search Tocris compounds for G6PC3

Search www.enzolifesicences.com for proteins, assays, substrates, inhibitors & antibodies

Search Novus for antibodies for G6PC3

GeneCards Homepage - Last full update: 2 Jul 2009 Incremental update: 13 Oct 2009

Random Gene From GIFtS :

about GIFtS

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Developed at the Crown Human Genome Center & Weizmann Institute of Science

The GeneCards Human Gene Database: Copyright © 1996-2009, Weizmann Institute of Science. All Rights Reserved.
G6PC3 Gene at Home site.
Version 2.41.1
server5.xennexinc.com

G6PC3 Gene

protein-coding GIFtS: 50

Aliases &
Descriptions
for G6PC3

Summaries
for G6PC3

Genomic Location
for G6PC3

Proteins
for G6PC3

Protein Domains/
Families
for G6PC3

Gene Function
for G6PC3

Pathways & Interactions
for G6PC3

Drugs & Compounds
for G6PC3

Transcripts
for G6PC3

Expression
for G6PC3

Orthologs
for G6PC3

Paralogs
for G6PC3

SNPs/Variants
for G6PC3

Disorders & Mutations
for G6PC3

Medical News
for G6PC3

Publications
for G6PC3

Search for G6PC3

Genome Databases showing G6PC3

Other Databases showing G6PC3

Specialized Databases showing G6PC3

Licensable Technologies
for G6PC3

Services
for G6PC3

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

G6PC3 Gene

protein-coding GIFtS: 50

Aliases & Descriptionsfor G6PC3

Summariesfor G6PC3

Genomic Locationfor G6PC3

Proteinsfor G6PC3

Protein Domains/Familiesfor G6PC3

Gene Functionfor G6PC3

Pathways & Interactionsfor G6PC3

Drugs & Compoundsfor G6PC3

Transcriptsfor G6PC3

Expression for G6PC3

Orthologsfor G6PC3

Paralogsfor G6PC3

SNPs/Variantsfor G6PC3

Disorders & Mutationsfor G6PC3

Medical Newsfor G6PC3

Publicationsfor G6PC3

Search for G6PC3

Genome Databases showing G6PC3

Other Databases showing G6PC3

Specialized Databases showing G6PC3

Licensable Technologiesfor G6PC3

Servicesfor G6PC3

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Aliases &
Descriptions
for G6PC3

Summaries
for G6PC3

Genomic Location
for G6PC3

Proteins
for G6PC3

Protein Domains/
Families
for G6PC3

Gene Function
for G6PC3

Pathways & Interactions
for G6PC3

Drugs & Compounds
for G6PC3

Transcripts
for G6PC3

Expression
for G6PC3

Orthologs
for G6PC3

Paralogs
for G6PC3

SNPs/Variants
for G6PC3

Disorders & Mutations
for G6PC3

Medical News
for G6PC3

Publications
for G6PC3

Licensable Technologies
for G6PC3

Services
for G6PC3