Aliases for FRAS1 Gene
External Ids for FRAS1 Gene
This gene encodes an extracellular matrix protein that appears to function in the regulation of epidermal-basement membrane adhesion and organogenesis during development. Mutations in this gene cause Fraser syndrome, a multisystem malformation that can include craniofacial, urogenital and respiratory system abnormalities. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009]
GeneCards Summary for FRAS1 Gene
FRAS1 (Fraser Extracellular Matrix Complex Subunit 1) is a Protein Coding gene. Diseases associated with FRAS1 include fraser syndrome and fras1-related fraser syndrome. Among its related pathways are ERK Signaling and ERK Signaling. An important paralog of this gene is FREM3.