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Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

FAM20A Gene

protein-coding GIFtS: 51
GCID: GC17M066533

Family With Sequence Similarity 20, Member A

6 related diseases
at

MalaCards

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, ¹⁰fRNAdb, ¹²H-InvDB, ¹³NCBI, ¹⁴NONCODE, and/or ¹⁵RNAdb)
About This Section

Aliases
Family With Sequence Similarity 20, Member A¹ ²
AIGFS²
FP2747²
Protein FAM20A²

External Ids:	HGNC: 23015¹	Entrez Gene: 54757²	Ensembl: ENSG00000108950⁷	OMIM: 611062⁵	UniProtKB: Q96MK3³

Export aliases for FAM20A gene to outside databases

Previous GC identifers: GC17M066995 GC17M067130 GC17M064044 GC17M061916

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for FAM20A Gene:

This locus encodes a protein that is likely secreted and may function in hematopoiesis. A mutation at this locus

has been associated with amelogenesis imperfecta and gingival hyperplasia syndrome. Alternatively spliced

transcript variants have been identified. (provided by RefSeq, Aug 2011)

GeneCards Summary for FAM20A Gene:

FAM20A (family with sequence similarity 20, member A) is a protein-coding gene. Diseases associated with FAM20A include amelogenesis imperfecta and gingival hyperplasia syndrome, and amelogenesis imperfecta hypoplastic type, ig. An important paralog of this gene is FAM20B.

Gene Wiki entry for FAM20A Gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000017.10 NC_018928.2 NT_010783.15

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the FAM20A gene promoter:
NF-1 AML1a POU3F2 (N-Oct-5a) IRF-1 POU3F2 Arnt AREB6 MEF-2A Msx-1 aMEF-2
Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: FAM20A promoter sequence

Search SABiosciences Chromatin IP Primers for FAM20A

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat FAM20A

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 17q24.2 Ensembl cytogenetic band: 17q24.2 HGNC cytogenetic band: 17q24.3

FAM20A Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
FAM20A gene location

GeneLoc information about chromosome 17 GeneLoc Exon Structure

GeneLoc location for GC17M066533: view genomic region (about GC identifiers)

Start:	66,531,254 bp from pter	End:	66,597,530 bp from pter
Size:	66,277 bases	Orientation:	minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE ¹MOPED, ²PaxDb, and ³MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: FA20A_HUMAN, Q96MK3 (See protein sequence)

Recommended Name: Protein FAM20A precursor

Size: 541 amino acids; 61417 Da

Subcellular location: Secreted (By similarity)

Secondary accessions: B2RN47 B2RN49 Q9UF95

Explore the universe of human proteins at neXtProt for FAM20A: NX_Q96MK3

Post-translational modifications:

UniProtKB: N-glycosylated (By similarity)

View modification sites using PhosphoSitePlus

View neXtProt modification sites for NX_Q96MK3

FAM20A Protein expression data from MOPED¹, PaxDb² and MAXQB³ : --

REFSEQ proteins (2 alternative transcripts):

NP_001230675.1 NP_060035.2

ENSEMBL proteins:

ENSP00000468308 ENSP00000467884 ENSP00000464910

Human Recombinant Protein Products for FAM20A:

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	Cloud-Clone Corp. Proteins for FAM20A

Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005576	extracellular region	IEA	--

FAM20A for ontologies About GeneDecksing

FAM20A Antibody Products:

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	Novus Biologicals FAM20A Antibodies
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	ThermoFisher Antibody for FAM20A
	LSBio Antibodies in human, mouse, rat for FAM20A

Assay Products for FAM20A:

	Browse Kits and Assays available from EMD Millipore
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	GenScript Custom Assay Services for FAM20A
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	Cloud-Clone Corp. ELISAs for FAM20A Cloud-Clone Corp. CLIAs for FAM20A

(According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

2 InterPro protein domains:

IPR009581 DUF1193

IPR024869 FAM20

Graphical View of Domain Structure for InterPro Entry Q96MK3

ProtoNet protein and cluster: Q96MK3

1 Blocks protein domain: IPB009581 Protein of unknown function DUF1193

UniProtKB/Swiss-Prot: FA20A_HUMAN, Q96MK3

Similarity: Belongs to the FAM20 family

FAM20A for domains About GeneDecksing

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
About This Section

Phenotypes:
1 GenomeRNAi human phenotype for FAM20A:

Increased gamma-H2AX phosphory

6 MGI mutant phenotypes (inferred from 1 allele) (MGI details for Fam20a):

cardiovascular system	craniofacial	growth/size	mortality/aging	renal/urinary system
respiratory system

FAM20A for phenotypes About GeneDecksing

Animal Models:
MGI mouse knock-out Fam20a^tm1Lex for FAM20A

inGenious Targeting Laboratory - Custom generated mouse model solutions for FAM20A

inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for FAM20A

genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for FAM20A

genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for FAM20A

miRNA Products:		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat FAM20A
		3 QIAGEN miScript miRNA Assays for microRNAs that regulate FAM20A:
		hsa-miR-520f hsa-miR-924 hsa-miR-3921
		SwitchGear 3'UTR luciferase reporter plasmid: FAM20A 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene RNAi products in human, mouse, rat for FAM20A
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Gene Editing Products:			DNA2.0 Custom Protein Engineering Service for FAM20A
			Sirion Biotech Customized adenovirus for overexpression of FAM20A

Clone Products:		Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
		OriGene clones in human, mouse for FAM20A (see all 7) OriGene ORF clones in mouse, rat for FAM20A OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector: FAM20A (NM_017565)
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		DNA2.0 Custom Codon Optimized Gene Synthesis Service for FAM20A
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Cell Line Products:		GenScript Custom overexpressing Cell Line Services for FAM20A
		Search LifeMap BioReagents cell lines for FAM20A

In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FAM20A

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
About This Section

Interactions:

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for FAM20A

Gene Ontology (GO): 1 biological process term (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0070166	enamel mineralization	IEA	--

FAM20A for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for FAM20A (FA20A)

Search CenterWatch for drugs/clinical trials and news about FAM20A / FA20A

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for FAM20A gene (2 alternative transcripts):

NM_001243746.1 NM_017565.3

Unigene Cluster for FAM20A:

Family with sequence similarity 20, member A

Hs.268874 [show with all ESTs]

Unigene Representative Sequence: NM_001243746

6 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000226094(uc002jhn.3 uc010wqp.2 uc002jho.3) ENST00000592554

ENST00000590873 ENST00000375556 ENST00000590074 ENST00000592847

miRNA Products:		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat FAM20A
		3 QIAGEN miScript miRNA Assays for microRNAs that regulate FAM20A:
		hsa-miR-520f hsa-miR-924 hsa-miR-3921
		SwitchGear 3'UTR luciferase reporter plasmid: FAM20A 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene RNAi products in human, mouse, rat for FAM20A
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat FAM20A

Clone Products:		OriGene clones in human, mouse for FAM20A (see all 7) OriGene ORF clones in mouse, rat for FAM20A OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector: FAM20A (NM_017565)
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for FAM20A
		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FAM20A
		Sirion Biotech Customized lentivirus for stable overexpression of FAM20A Customized lentivirus expression plasmids for stable overexpression of FAM20A

Primer Products:		OriGene qSTAR qPCR primer pairs in human, mouse for FAM20A
		SABiosciences RT² qPCR Primer Assay in human, mouse, rat FAM20A
		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat FAM20A
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat FAM20A

Additional mRNA sequence:

AB545606.1 AK056789.1 AK298071.1 AL133105.1 AY358197.1 BC036222.1 BC136686.1 BC136689.1

NR_027751.1

11 DOTS entries:

DT.97781965 DT.100742066 DT.91686027 DT.97776150 DT.100737227 DT.455153 DT.121011506 DT.121011469

DT.121011442 DT.91848322 DT.95315373

24/102 AceView cDNA sequences (see all 102):

BX110034 BU741994 CD358576 AL133105 AI128237 CA944755 AI763057 AI823909

AV650290 AI123563 AF447872 BX503337 AI857676 AI202236 CR597331 CB530015

AI244363 BU626202 AI738519 BE857141 AW515749 AK127041 AY358197 AK130720

GeneLoc Exon Structure

2 Alternative Splicing Database (ASD) splice patterns (SP) for FAM20A About this scheme

ExUns:	1	^	2	^	3	^	4	^	5	^	6	^	7	^	8	^	9a	·	9b	^	10	^	11	^	12a	·	12b
SP1:			-														-
SP2:

ECgene alternative splicing isoforms for FAM20A

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

FAM20A expression in normal human tissues (normalized intensities) FAM20A embryonic expression: see
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>^2/3
CGAP TAG: --

About this image

FAM20A expression in embryonic tissues and stem cells About this table

Data from LifeMap, the Embryonic Development and Stem Cells Database

5/4 selected tissues (see all 4) fully expand


Mesenchymal Stem Cells (Muscoskeletal System) fully expand to see all 3 entries
Human Mesenchymal Stem Cells (hMSC)-1

Bone (Muscoskeletal System) fully expand to see all 2 entries
Zeugopod Epiphyseal End

Neural Crest (Gastrulation Derivatives)
PureStem MEL2, NCr-fac Progenitor

Skeletal Muscle (Muscoskeletal System)
Human Skeletal Muscle Satellite Cells (HSkMSC)

Genevestigator expression for FAM20A

SOURCE GeneReport for Unigene cluster: Hs.268874

UniProtKB/Swiss-Prot: FA20A_HUMAN, Q96MK3

Tissue specificity: Highly expressed in lung and liver. Intermediate levels in thymus and ovary

SABiosciences Custom PCR Arrays for FAM20A

Primer Products:		OriGene qSTAR qPCR primer pairs in human, mouse for FAM20A
		SABiosciences RT² qPCR Primer Assay in human, mouse, rat FAM20A
		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat FAM20A
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat FAM20A

In Situ
Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FAM20A

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of animals.

Orthologs for FAM20A gene from 6/12 species (see all 12) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
mouse (Mus musculus)	Mammalia	Fam20a^{1 , 5}	family with sequence similarity 20, member A^{1, 5}	85.52(n)¹ 85.77(a)¹		11 (72.37 cM)⁵ 208659¹ NM_153782.1¹ NP_722477.1¹ 109669749⁵
chicken (Gallus gallus)	Aves	FAM20A¹	family with sequence similarity 20, member A	76.29(n) 77.5(a)		417439 XM_415690.3 XP_415690.3
lizard (Anolis carolinensis)	Reptilia	FAM20A⁶	family with sequence similarity 20, member A	73(a)	1 ↔ 1	GL343260.1(1724494-1820183)
zebrafish (Danio rerio)	Actinopterygii	Dr.22208²	Transcribed sequence with weak similarity to protein more	74.91(n)		CK399583.1
fruit fly (Drosophila melanogaster)	Insecta	CG31145⁶	--	19(a)	1 → many	3R(19431473-19495378)
worm (Caenorhabditis elegans)	Secernentea	H03A11.1⁶	Protein H03A11.1	30(a)	1 → many	X(15209291-15213259)

ENSEMBL Gene Tree for FAM20A (if available)
TreeFam Gene Tree for FAM20A (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for FAM20A gene

FAM20B² FAM20C²

5 SIMAP similar genes for FAM20A using alignment to 4 protein entries: FA20A_HUMAN (see all proteins):

FP2747 Fam20A FAM20C Fam20C FAM20B

FAM20A for paralogs About GeneDecksing

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, ⁴UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 17 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs140271776^1,2	C	--	61926587(+)	`TACAG-/CACAAC`	3	--	int¹		0	--	--	--	--
rs148889544^1,2	C	--	61929898(+)	`CAATA-/TTGTTGTG`	3	--	int¹		0	--	--	--	--
rs202214787^1,2	C	--	61935909(+)	`CACAC-/ATATGCA`	3	--	int¹		0	--	--	--	--
rs35576157^1,2	C	--	61950673(+)	`TTATC-/TCTTCA`	2	--	int¹		0	--	--	--	--
rs71355891^1,2	C	--	61953883(+)	`TATAT-/A/AT ATATATATATAT`	4	--	int¹ cds¹		1		NA	2
rs189368792^1,2		--	61953894(+)	`ATATAC/TATATA`	2	--	int¹		0	--	--	--	--
rs60840224^1,2	C	--	61961832(+)	`ATAGT-/ATTGCA`	2	--	int¹		0	--	--	--	--
rs145262085^1,2	C	--	61961834(+)	`AGTTT-/AA/TAA GCATT`	4	--	int¹ cds¹		0	--	--	--	--
rs56719534^1,2	C	--	61961836(+)	`GTTTG-/AA/A AA/TAACATTT`	6	--	int¹ cds¹		0	--	--	--	--
rs80175922^1,2		--	61972745(+)	`CCTGGA/C/GCCAAT`	2	--	int¹		0	--	--	--	--

HapMap Linkage Disequilibrium report for FAM20A (66531254 - 66597530 bp)

Structural Variations
Database of Genomic Variants (DGV) 7 variations for FAM20A: About this table

Variant ID	Type	Subtype	PubMed ID
esv2716148	CNV	Deletion	23290073
esv2661984	CNV	Deletion	23128226
esv2677068	CNV	Deletion	23128226
nsv507856	CNV	Insertion	20534489
nsv522126	CNV	Loss	19592680
nsv510723	CNV	Loss	20534489
nsv833524	CNV	Gain	17160897

Human Gene Mutation Database (HGMD): FAM20A

SABiosciences Cancer Mutation PCR Assays

QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing FAM20A

DNA2.0 Custom Variant and Variant Library Synthesis for FAM20A

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

OMIM gene information: 611062 OMIM disorders: --

UniProtKB/Swiss-Prot: FA20A_HUMAN, Q96MK3

Amelogenesis imperfecta and gingival fibromatosis syndrome (AIGFS) [MIM:614253]: An autosomal recessive

condition characterized by mild gingival fibromatosis and dental anomalies, including hypoplastic amelogenesis

imperfecta, intrapulpal calcifications, delay of tooth eruption, hypodontia/oligodontia, pericoronal

radiolucencies, and unerupted teeth. Note=The disease is caused by mutations affecting the gene represented in

this entry

6 diseases for FAM20A: About MalaCards

amelogenesis imperfecta and gingival hyperplasia syndrome amelogenesis imperfecta hypoplastic type, ig pericoronitis gingivitis

amelogenesis imperfecta fibromatosis

2 diseases from the University of Copenhagen DISEASES database for FAM20A:

Hypercementosis Amelogenesis imperfecta

FAM20A for disorders About GeneDecksing

Genetic Association Database (GAD): FAM20A

Export disorders for FAM20A gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
About This Section

PubMed articles for FAM20A gene, integrated from 9 sources (see all 12):
(articles sorted by number of sources associating them with FAM20A)

Utopia: connect your pdf to the dynamic
world of online information

FAM20: an evolutionarily conserved family of secreted proteins expressed in hematopoietic cells. (PubMed id 15676076)^{1, 2, 9} Nalbant D.... Williams S.C. (2005)
Novel FAM20A mutations in hypoplastic amelogenesis imperfecta. (PubMed id 21990045)^{1, 2} Cho S.H....Kim J.W. (2011)
Whole-Exome sequencing identifies FAM20A mutations as a cause of amelogenesis imperfecta and gingival hyperplasia syndrome. (PubMed id 21549343)^{1, 2} O'Sullivan J....Dixon M.J. (2011)
Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)^{1, 2} Ota T.... Sugano S. (2004)
The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PubMed id 12975309)^{1, 2} Clark H.F.... Gray A.M. (2003)
FAM20A mutations can cause enamel-renal syndrome (ERS) . (PubMed id 23468644)¹ Wang S.K....Hu J.C. (2013)
Altered gene expression pattern in peripheral blood mo nonuclear cells in patients with acute myocardial infarction. (PubMed id 23185530)¹ Kiliszek M....Opolski G. (2012)
The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005)² Bechtel S.... Schupp I. (2007)
Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)¹ Kimura K.... Sugano S. (2006)
DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage. (PubMed id 16625196)² Zody M.C.... Nusbaum C. (2006)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section

Entrez Gene: 54757	HGNC: 23015	AceView: FAM20A	Ensembl:ENSG00000108950	euGenes: HUgn54757
ECgene: FAM20A	H-InvDB: FAM20A

(According to HUGE)
About This Section

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
PharmGKB entry for FAM20A	Pharmacogenomics, SNPs, Pathways

Intellectual Property for FAM20A gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

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Patent Information for FAM20A gene:
Search GeneIP for patents involving FAM20A

GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search

(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
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GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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Category			TGFB1 (GIFtS: 73) transforming growth factor, beta 1
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FAM20A Gene

Family With Sequence Similarity 20, Member A

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for FAM20A gene

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FAM20A Gene

Family With Sequence Similarity 20, Member A

Aliasesfor FAM20A gene

Summariesfor FAM20A gene

Genomic Viewsfor FAM20A gene

Proteinsfor FAM20A gene

Protein Domains /Familiesfor FAM20A gene

Functionfor FAM20A gene

Pathways & Interactionsfor FAM20A gene

Drugs & Compoundsfor FAM20A gene

Transcriptsfor FAM20A gene

Expression for FAM20A gene

Orthologsfor FAM20A gene

Paralogsfor FAM20A gene

Genomic Variantsfor FAM20A gene

Disorders / Diseasesfor FAM20A gene

Publicationsfor FAM20A gene

External Searches for FAM20A gene

Genome Databases showing FAM20A gene

Other Databases showing FAM20A gene

Specialized Databases showing FAM20A gene

Intellectual Propertyfor FAM20A gene

Productsfor FAM20A gene

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Aliases
for FAM20A gene

Summaries
for FAM20A gene

Genomic Views
for FAM20A gene

Proteins
for FAM20A gene

Protein Domains /
Families
for FAM20A gene

Function
for FAM20A gene

Pathways & Interactions
for FAM20A gene

Drugs & Compounds
for FAM20A gene

Transcripts
for FAM20A gene

Expression
for FAM20A gene

Orthologs
for FAM20A gene

Paralogs
for FAM20A gene

Genomic Variants
for FAM20A gene

Disorders / Diseases
for FAM20A gene

Publications
for FAM20A gene

Intellectual Property
for FAM20A gene

Products
for FAM20A gene