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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

FAM20A Gene

protein-coding   GIFtS: 51
GCID: GC17M066533

Family With Sequence Similarity 20, Member A

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Family With Sequence Similarity 20, Member A1 2
AIGFS2
FP27472
Protein FAM20A2

External Ids:    HGNC: 230151   Entrez Gene: 547572   Ensembl: ENSG000001089507   OMIM: 6110625   UniProtKB: Q96MK33   

Export aliases for FAM20A gene to outside databases

Previous GC identifers: GC17M066995 GC17M067130 GC17M064044 GC17M061916


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for FAM20A Gene:
This locus encodes a protein that is likely secreted and may function in hematopoiesis. A mutation at this locus
has been associated with amelogenesis imperfecta and gingival hyperplasia syndrome. Alternatively spliced
transcript variants have been identified. (provided by RefSeq, Aug 2011)

GeneCards Summary for FAM20A Gene: 
FAM20A (family with sequence similarity 20, member A) is a protein-coding gene. Diseases associated with FAM20A include amelogenesis imperfecta and gingival hyperplasia syndrome, and amelogenesis imperfecta hypoplastic type, ig. An important paralog of this gene is FAM20B.

Gene Wiki entry for FAM20A Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000017.10  NC_018928.2  NT_010783.15  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the FAM20A gene promoter:
         NF-1   AML1a   POU3F2 (N-Oct-5a)   IRF-1   POU3F2   Arnt   AREB6   MEF-2A   Msx-1   aMEF-2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidFAM20A promoter sequence
   Search SABiosciences Chromatin IP Primers for FAM20A

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat FAM20A


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 17q24.2   Ensembl cytogenetic band:  17q24.2   HGNC cytogenetic band: 17q24.3

FAM20A Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
FAM20A gene location

GeneLoc information about chromosome 17         GeneLoc Exon Structure

GeneLoc location for GC17M066533:  view genomic region     (about GC identifiers)

Start:
66,531,254 bp from pter      End:
66,597,530 bp from pter
Size:
66,277 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: FA20A_HUMAN, Q96MK3 (See protein sequence)
Recommended Name: Protein FAM20A precursor  
Size: 541 amino acids; 61417 Da
Subcellular location: Secreted (By similarity)
Secondary accessions: B2RN47 B2RN49 Q9UF95

Explore the universe of human proteins at neXtProt for FAM20A: NX_Q96MK3

Post-translational modifications:

  • UniProtKB: N-glycosylated (By similarity)
  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q96MK3

  • FAM20A Protein expression data from MOPED1, PaxDb2 and MAXQB3 : --
    REFSEQ proteins (2 alternative transcripts): 
    NP_001230675.1  NP_060035.2  

    ENSEMBL proteins: 
     ENSP00000468308   ENSP00000467884   ENSP00000464910  

    Human Recombinant Protein Products for FAM20A: 
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    Novus Biologicals FAM20A Lysate
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for FAM20A 

    Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005576extracellular region IEA--

    FAM20A for ontologies           About GeneDecksing



    FAM20A Antibody Products: 
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    LSBio Antibodies in human, mouse, rat for FAM20A 

    Assay Products for FAM20A: 
    Browse Kits and Assays available from EMD Millipore
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    Cloud-Clone Corp. ELISAs for FAM20A 
    Cloud-Clone Corp. CLIAs for FAM20A


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    2 InterPro protein domains:
     IPR009581 DUF1193
     IPR024869 FAM20

    Graphical View of Domain Structure for InterPro Entry Q96MK3

    ProtoNet protein and cluster: Q96MK3

    1 Blocks protein domain: IPB009581 Protein of unknown function DUF1193

    UniProtKB/Swiss-Prot: FA20A_HUMAN, Q96MK3
    Similarity: Belongs to the FAM20 family


    FAM20A for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Phenotypes:
         1 GenomeRNAi human phenotype for FAM20A:
     Increased gamma-H2AX phosphory 

         6 MGI mutant phenotypes (inferred from 1 allele(MGI details for Fam20a):
     cardiovascular system  craniofacial  growth/size  mortality/aging  renal/urinary system 
     respiratory system 

    FAM20A for phenotypes           About GeneDecksing

    Animal Models:
         MGI mouse knock-out Fam20atm1Lex for FAM20A

       inGenious Targeting Laboratory - Custom generated mouse model solutions for FAM20A 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for FAM20A

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for FAM20A 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for FAM20A 

    miRNA
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    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat FAM20A
    3 QIAGEN miScript miRNA Assays for microRNAs that regulate FAM20A:
    hsa-miR-520f hsa-miR-924 hsa-miR-3921
    SwitchGear 3'UTR luciferase reporter plasmidFAM20A 3' UTR sequence
    Inhib. RNA
    Products:
        
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for FAM20A
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    Gene Editing
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    Clone
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    OriGene ORF clones in mouse, rat for FAM20A
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    GenScript: all cDNA clones in your preferred vector: FAM20A (NM_017565)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for FAM20A
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                         Customized lentivirus expression plasmids for stable overexpression of FAM20A 

    Cell Line
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    Search LifeMap BioReagents cell lines for FAM20A
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FAM20A


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for FAM20A

    Gene Ontology (GO): 1 biological process term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0070166enamel mineralization IEA--

    FAM20A for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for FAM20A (FA20A)

    Search CenterWatch for drugs/clinical trials and news about FAM20A / FA20A

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for FAM20A gene (2 alternative transcripts): 
    NM_001243746.1  NM_017565.3  

    Unigene Cluster for FAM20A:

    Family with sequence similarity 20, member A
    Hs.268874  [show with all ESTs]
    Unigene Representative Sequence: NM_001243746
    6 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000226094(uc002jhn.3 uc010wqp.2 uc002jho.3) ENST00000592554
    ENST00000590873 ENST00000375556 ENST00000590074 ENST00000592847
    miRNA
    Products:
         
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat FAM20A
    3 QIAGEN miScript miRNA Assays for microRNAs that regulate FAM20A:
    hsa-miR-520f hsa-miR-924 hsa-miR-3921
    SwitchGear 3'UTR luciferase reporter plasmidFAM20A 3' UTR sequence
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for FAM20A
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat FAM20A
    Clone
    Products:
         
    OriGene clones in human, mouse for FAM20A (see all 7)
    OriGene ORF clones in mouse, rat for FAM20A
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: FAM20A (NM_017565)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for FAM20A
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FAM20A
    Sirion Biotech Customized lentivirus for stable overexpression of FAM20A 
                         Customized lentivirus expression plasmids for stable overexpression of FAM20A 
    Primer
    Products:
        
    OriGene qSTAR qPCR primer pairs in human, mouse for FAM20A
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat FAM20A
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat FAM20A
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat FAM20A

    Additional mRNA sequence: 

    AB545606.1 AK056789.1 AK298071.1 AL133105.1 AY358197.1 BC036222.1 BC136686.1 BC136689.1 
    NR_027751.1 

    11 DOTS entries:

    DT.97781965  DT.100742066  DT.91686027  DT.97776150  DT.100737227  DT.455153  DT.121011506  DT.121011469 
    DT.121011442  DT.91848322  DT.95315373 

    24/102 AceView cDNA sequences (see all 102):

    BX110034 BU741994 CD358576 AL133105 AI128237 CA944755 AI763057 AI823909 
    AV650290 AI123563 AF447872 BX503337 AI857676 AI202236 CR597331 CB530015 
    AI244363 BU626202 AI738519 BE857141 AW515749 AK127041 AY358197 AK130720 

    GeneLoc Exon Structure

    2 Alternative Splicing Database (ASD) splice patterns (SP) for FAM20A    About this scheme

    ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9a · 9b ^ 10 ^ 11 ^ 12a · 12b
    SP1:        -                                         -                                 
    SP2:                                                                                    


    ECgene alternative splicing isoforms for FAM20A

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    FAM20A expression in normal human tissues (normalized intensities)      FAM20A embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    FAM20A Expression
    About this image


    FAM20A expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/4 selected tissues (see all 4) fully expand
     
     Mesenchymal Stem Cells (Muscoskeletal System)    fully expand to see all 3 entries
             Human Mesenchymal Stem Cells (hMSC)-1   
     
     Bone (Muscoskeletal System)    fully expand to see all 2 entries
             Zeugopod Epiphyseal End
     
     Neural Crest (Gastrulation Derivatives)
             PureStem MEL2, NCr-fac Progenitor
     
     Skeletal Muscle (Muscoskeletal System)
             Human Skeletal Muscle Satellite Cells (HSkMSC)   

    Genevestigator expression for FAM20A

    SOURCE GeneReport for Unigene cluster: Hs.268874

    UniProtKB/Swiss-Prot: FA20A_HUMAN, Q96MK3
    Tissue specificity: Highly expressed in lung and liver. Intermediate levels in thymus and ovary

        SABiosciences Custom PCR Arrays for FAM20A
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FAM20A

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for FAM20A gene from 6/12 species (see all 12)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Fam20a1 , 5 family with sequence similarity 20, member A1, 5 85.52(n)1
    85.77(a)1
      11 (72.37 cM)5
    2086591  NM_153782.11  NP_722477.11 
     1096697495 
    chicken
    (Gallus gallus)
    Aves FAM20A1 family with sequence similarity 20, member A 76.29(n)
    77.5(a)
      417439  XM_415690.3  XP_415690.3 
    lizard
    (Anolis carolinensis)
    Reptilia FAM20A6
    family with sequence similarity 20, member A
    73(a)
    1 ↔ 1
    GL343260.1(1724494-1820183)
    zebrafish
    (Danio rerio)
    Actinopterygii Dr.222082 Transcribed sequence with weak similarity to protein more 74.91(n)    CK399583.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG311456
    --
    19(a)
    1 → many
    3R(19431473-19495378)
    worm
    (Caenorhabditis elegans)
    Secernentea H03A11.16
    Protein H03A11.1
    30(a)
    1 → many
    X(15209291-15213259)


    ENSEMBL Gene Tree for FAM20A (if available)
    TreeFam Gene Tree for FAM20A (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for FAM20A gene
    FAM20B2  FAM20C2  
    5 SIMAP similar genes for FAM20A using alignment to 4 protein entries:     FA20A_HUMAN (see all proteins):
    FP2747    Fam20A    FAM20C    Fam20C    FAM20B

    FAM20A for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/1513 SNPs in FAM20A are shown (see all 1513)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 17 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1402717761,2
    C--61926587(+) TACAG-/CACAAC 3 -- int10--------
    rs1488895441,2
    C--61929898(+) CAATA-/TTGTTGTG 3 -- int10--------
    rs2022147871,2
    C--61935909(+) CACAC-/ATATGCA 3 -- int10--------
    rs355761571,2
    C--61950673(+) TTATC-/TCTTCA 2 -- int10--------
    rs713558911,2
    C--61953883(+) TATAT-/A/AT  
     ATATATA
    TATAT
    4 -- int1 cds11NA 2
    rs1893687921,2
    --61953894(+) ATATAC/TATATA 2 -- int10--------
    rs608402241,2
    C--61961832(+) ATAGT-/ATTGCA 2 -- int10--------
    rs1452620851,2
    C--61961834(+) AGTTT-/AA/TAA
            
    GCATT
    4 -- int1 cds10--------
    rs567195341,2
    C--61961836(+) GTTTG-/AA/A  
      AA
    /TAA
    CATTT
    6 -- int1 cds10--------
    rs801759221,2
    --61972745(+) CCTGGA/C/GCCAAT 2 -- int10--------

    HapMap Linkage Disequilibrium report for FAM20A (66531254 - 66597530 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 7 variations for FAM20A:    About this table     
    Variant IDTypeSubtypePubMed ID
    esv2716148CNV Deletion23290073
    esv2661984CNV Deletion23128226
    esv2677068CNV Deletion23128226
    nsv507856CNV Insertion20534489
    nsv522126CNV Loss19592680
    nsv510723CNV Loss20534489
    nsv833524CNV Gain17160897


    Human Gene Mutation Database (HGMD): FAM20A
    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing FAM20A
    DNA2.0 Custom Variant and Variant Library Synthesis for FAM20A

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 611062    OMIM disorders: --

    UniProtKB/Swiss-Prot: FA20A_HUMAN, Q96MK3
  • Amelogenesis imperfecta and gingival fibromatosis syndrome (AIGFS) [MIM:614253]: An autosomal recessive
    condition characterized by mild gingival fibromatosis and dental anomalies, including hypoplastic amelogenesis
    imperfecta, intrapulpal calcifications, delay of tooth eruption, hypodontia/oligodontia, pericoronal
    radiolucencies, and unerupted teeth. Note=The disease is caused by mutations affecting the gene represented in
    this entry

  • 6 diseases for FAM20A:    About MalaCards
    amelogenesis imperfecta and gingival hyperplasia syndrome    amelogenesis imperfecta hypoplastic type, ig    pericoronitis    gingivitis
    amelogenesis imperfecta    fibromatosis

    2 diseases from the University of Copenhagen DISEASES database for FAM20A:
    Hypercementosis     Amelogenesis imperfecta

    FAM20A for disorders           About GeneDecksing

    Genetic Association Database (GAD): FAM20A

    Export disorders for FAM20A gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for FAM20A gene, integrated from 9 sources (see all 12):
    (articles sorted by number of sources associating them with FAM20A)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. FAM20: an evolutionarily conserved family of secreted proteins expressed in hematopoietic cells. (PubMed id 15676076)1, 2, 9 Nalbant D.... Williams S.C. (2005)
    2. Novel FAM20A mutations in hypoplastic amelogenesis imperfecta. (PubMed id 21990045)1, 2 Cho S.H....Kim J.W. (2011)
    3. Whole-Exome sequencing identifies FAM20A mutations as a cause of amelogenesis imperfecta and gingival hyperplasia syndrome. (PubMed id 21549343)1, 2 O'Sullivan J....Dixon M.J. (2011)
    4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    5. The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PubMed id 12975309)1, 2 Clark H.F.... Gray A.M. (2003)
    6. FAM20A mutations can cause enamel-renal syndrome (ERS) . (PubMed id 23468644)1 Wang S.K....Hu J.C. (2013)
    7. Altered gene expression pattern in peripheral blood mo nonuclear cells in patients with acute myocardial infarction. (PubMed id 23185530)1 Kiliszek M....Opolski G. (2012)
    8. The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005)2 Bechtel S.... Schupp I. (2007)
    9. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (2006)
    10. DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage. (PubMed id 16625196)2 Zody M.C.... Nusbaum C. (2006)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 54757 HGNC: 23015 AceView: FAM20A Ensembl:ENSG00000108950 euGenes: HUgn54757
    ECgene: FAM20A H-InvDB: FAM20A

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for FAM20A Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for FAM20A gene:
    Search GeneIP for patents involving FAM20A

    GeneCards and IP:
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