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Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

FYTTD1 Gene

protein-coding GIFtS: 47
GCID: GC03P197464

forty-two-three domain containing 1

Explore 1 disease affiliated with
FYTTD1 via

MalaCards

our new
Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

This gene clusters with an RNA gene
Subcategory (RNA class): lncRNA

Quality score for the ORGUL clustered with this gene is 3

Aliases
Forty-Two-Three Domain Containing 1¹ ²
UIF¹ ² ³
Forty-Two-Three Domain-Containing Protein 1² ³
Protein 40-2-3² ³
DKFZp761B1514¹
UAP56-Interacting Factor²

External Ids:	HGNC: 25407¹	Entrez Gene: 84248²	Ensembl: ENSG00000122068⁷	UniProtKB: Q96QD9³

ORGUL members:
	NONCODE:n408048

Export aliases for FYTTD1 gene to outside databases

Previous GC identifers: GC03P198965 GC03P194779

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

UniProtKB/Swiss-Prot: UIF_HUMAN, Q96QD9

Function: Required for mRNA export from the nucleus to the cytoplasm. Acts as an adapter that uses the

DDX39B/UAP56-NFX1 pathway to ensure efficient mRNA export and delivering to the nuclear pore. Associates with spliced

and unspliced mRNAs simultaneously with ALYREF/THOC4

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000003.11 NC_018914.1 NT_029928.13

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the FYTTD1 gene promoter:
c-Fos RP58 AP-1 POU3F2 (N-Oct-5a) POU3F2 (N-Oct-5b) POU3F2 CREB MZF-1 c-Jun Ik-1
Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: FYTTD1 promoter sequence

Search SABiosciences Chromatin IP Primers for FYTTD1

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat FYTTD1

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 3q29 Ensembl cytogenetic band: 3q29 HGNC cytogenetic band: 3q29

FYTTD1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
FYTTD1 gene location

GeneLoc information about chromosome 3 GeneLoc Exon Structure

GeneLoc location for GC03P197464: view genomic region (about GC identifiers)

Start:	197,464,050 bp from pter	End:	197,511,317 bp from pter
Size:	47,268 bases	Orientation:	plus strand

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: UIF_HUMAN, Q96QD9 (See protein sequence)

Recommended Name: UAP56-interacting factor

Size: 318 amino acids; 35818 Da

Subunit: Interacts with CHTOP (By similarity). Interacts with DDX39B/UAP56 and NXF1; interaction with DDX39B/UAP56 and

NXF1 are mutually exclusive. Interacts with SSRP1; required for its recruitment to mRNAs

Subcellular location: Nucleus, nucleoplasm. Nucleus speckle

Secondary accessions: A8MY74 B2RCB2 B7Z3R4 B7Z7V1 B7Z8I0 B7ZAJ3 C9J7P6 C9JNG6 C9JTH3 C9JY50 Q96SL9

Q9BQI8

Alternative splicing: 4 isoforms: Q96QD9-1 Q96QD9-2 Q96QD9-3 Q96QD9-4 (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for FYTTD1: NX_Q96QD9

Post-translational modifications:

View modification sites using PhosphoSitePlus²

View neXtProt modification sites for NX_Q96QD9

FYTTD1 Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins (2 alternative transcripts):

NP_001011537.2 NP_115664.2

ENSEMBL proteins:

ENSP00000399896 ENSP00000417742 ENSP00000393746 ENSP00000241502 ENSP00000409257

ENSP00000400191 ENSP00000389557 ENSP00000394631 ENSP00000391157

Human Recombinant Protein Products:

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	Novus Biologicals FYTTD1 Protein Novus Biologicals FYTTD1 Lysate
	Browse Sino Biological Recombinant Proteins
	Browse ProSpec Recombinant Proteins
	Uscn Proteins for FYTTD1

Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005654	nucleoplasm	IDA	19836239
GO:0016607	nuclear speck	IDA	19836239

FYTTD1 for ontologies About GeneDecksing

FYTTD1 Antibody Products:

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	Uscn Antibodies for FYTTD1
	ThermoFisher Antibodies for FYTTD1

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	GenScript Custom Assay Services for FYTTD1
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	Uscn ELISAs and CLIAs for FYTTD1

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

FYTTD1 for domains About GeneDecksing

1 InterPro domain/family:

IPR009782 DUF1346

Graphical View of Domain Structure for InterPro Entry Q96QD9

ProtoNet protein and cluster: Q96QD9

UniProtKB/Swiss-Prot: UIF_HUMAN, Q96QD9

Similarity: Belongs to the UIF family

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

Function Summary:

UniProtKB/Swiss-Prot: UIF_HUMAN, Q96QD9

Function: Required for mRNA export from the nucleus to the cytoplasm. Acts as an adapter that uses the

DDX39B/UAP56-NFX1 pathway to ensure efficient mRNA export and delivering to the nuclear pore. Associates with spliced

and unspliced mRNAs simultaneously with ALYREF/THOC4

miRNA Products:		OriGene 3'-UTR Clone (see all 2): FYTTD1 Browse MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat FYTTD1
		8/44 QIAGEN miScript miRNA Assays for microRNAs that regulate FYTTD1 (see all 44):
		hsa-miR-411* hsa-miR-21* hsa-miR-2052 hsa-miR-4307 hsa-miR-19b-2* hsa-miR-379* hsa-miR-300 hsa-miR-548k

		SwitchGear 3'UTR luciferase reporter plasmid: FYTTD1 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for FYTTD1 (see all 7) OriGene shRNA RFP: FYTTD1 OriGene siRNA: FYTTD1
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Gene Editing
Products:

DNA2.0 Custom Protein Engineering Service for FYTTD1

Clone Products:		Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
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		GenScript: all cDNA clones in your preferred vector (see all 2): FYTTD1 (NM_032288)
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		DNA2.0 Custom Codon Optimized Gene Synthesis Service for FYTTD1
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Cell Line Products:		GenScript Custom overexpressing Cell Line Services for FYTTD1
		Search LifeMap BioReagents cell lines for FYTTD1

In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FYTTD1

Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0003729	mRNA binding	IDA	19836239
GO:0005515	protein binding	IPI	19836239

FYTTD1 for ontologies About GeneDecksing

3 GenomeRNAi human phenotypes for FYTTD1:

G0/1 arrest

Increased G1 DNA content

Increased HPV18 LCR reporter a

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Interactions:

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for FYTTD1

STRING Interaction Network Preview (showing 3 interactants - click image to see more details)

5/561 Interacting proteins for FYTTD1 (Q96QD9^{2, 3} ENSP00000241502⁴) via UniProtKB, MINT, STRING, and/or I2D (see all 561)

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
TSPAN7	P41732²^,³, ENSP00000367743⁴	MINT-65312 I2D: score=3 STRING: ENSP00000367743
SHBG	P04278³, ENSP00000369816⁴	I2D: score=2 STRING: ENSP00000369816
SNW1	Q13573², ENSP00000261531⁴	MINT-7945693 STRING: ENSP00000261531
E2F4	Q16254³	I2D: score=1
ABCF1	Q8NE71²	MINT-7945693

About this table

Gene Ontology (GO): 1 biological process term (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0006406	mRNA export from nucleus	IMP	19836239

FYTTD1 for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for FYTTD1
Search CenterWatch for drugs/clinical trials and news about FYTTD1 / UIF

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for FYTTD1 gene (2 alternative transcripts):

NM_001011537.2 NM_032288.6

Unigene Cluster for FYTTD1:

Forty-two-three domain containing 1

Hs.277533 [show with all ESTs]

Unigene Representative Sequence: NR_027840

11 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000428738 ENST00000494309 ENST00000415708 ENST00000241502(uc003fyi.2 uc011buj.1)

ENST00000412924 ENST00000418169 ENST00000426031 ENST00000424384 ENST00000463136

ENST00000492360 ENST00000428395(uc011bui.1 uc011buk.1)

miRNA Products:		OriGene 3'-UTR Clone (see all 2): FYTTD1 Browse OriGene MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat FYTTD1
		8/44 QIAGEN miScript miRNA Assays for microRNAs that regulate FYTTD1 (see all 44):
		hsa-miR-411* hsa-miR-21* hsa-miR-2052 hsa-miR-4307 hsa-miR-19b-2* hsa-miR-379* hsa-miR-300 hsa-miR-548k

		SwitchGear 3'UTR luciferase reporter plasmid: FYTTD1 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for FYTTD1 (see all 7) OriGene shRNA RFP: FYTTD1 OriGene siRNA: FYTTD1
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat FYTTD1

Clone Products:		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for FYTTD1 (see all 6) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for FYTTD1 (see all 3) OriGene custom cloning services � gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector (see all 2): FYTTD1 (NM_032288)
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for FYTTD1
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Primer Products:		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for FYTTD1 Browse OriGene validated miRNA SYBR primer pairs
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		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat FYTTD1
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat FYTTD1

Additional cDNA sequence:

AJ344094.1 AK027672.1 AK296283.1 AK302546.1 AK303462.1 AK315019.1 AK316308.1 AL136558.1

BC013602.1 BC035006.2 BC039734.1 CR533502.1 NR_027840.1

14 DOTS entries:

DT.213532 DT.456152 DT.75147510 DT.99994583 DT.100788008 DT.92438559 DT.120895014 DT.95219637

DT.95219638 DT.95239387 DT.120894998 DT.120895005 DT.92026734 DT.92438563

24/330 AceView cDNA sequences (see all 330):

BU172511 AA291448 AA988436 AW572185 CF272295 AI610694 AI337856 F11938

AA262528 AJ344094 BU742585 AI459115 AI804478 CB163123 F13197 AA648995

AI128265 AI002048 CB152034 BQ223771 BU685698 AA360473 BU517024 AA688088

GeneLoc Exon Structure

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

FYTTD1 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: --

About this image

FYTTD1 expression in embryonic tissues and stem cells

Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine About this table

2 LifeMap In Vivo Development Anatomical Compartments/Cells

Tissue

Anatomical Compartment

Cell

Category (developmental path)

Kidney

Reproductive System

Expression:

Positive

Negative

Selective marker

Experimental details:

Curated

Microarrays

In-situ hybridization

See FYTTD1 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for FYTTD1

SOURCE GeneReport for Unigene cluster: Hs.277533

SABiosciences Custom PCR Arrays for FYTTD1

Primer Products:		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for FYTTD1 Browse OriGene validated miRNA SYBR primer pairs
		SABiosciences RT² qPCR Primer Assay in human, mouse, rat FYTTD1
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		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat FYTTD1

In Situ
Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FYTTD1

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of chordates.

Orthologs for FYTTD1 gene from 4/10 species (see all 10) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
mouse (Mus musculus)	Mammalia	Fyttd1^{1 , 5}	forty-two-three domain containing 1^{1, 5}	88.22(n)¹ 92.74(a)¹		16 (23.43 cM)⁵ 69823¹ NM_027226.4¹ NP_081502.2¹ 32877500⁵
chicken (Gallus gallus)	Aves	FYTTD1¹	forty-two-three domain containing 1	70.26(n) 64.38(a)		424921 NM_001031316.1 NP_001026487.1
lizard (Anolis carolinensis)	Reptilia	FYTTD1⁶	--	65(a)	1 ↔ 1	GL343433.1(307389-326684)
African clawed frog (Xenopus laevis)	Amphibia	BC044288.1²	--	74.33(n)		BC044288.1

ENSEMBL Gene Tree for FYTTD1 (if available)
TreeFam Gene Tree for FYTTD1 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for FYTTD1 gene

FYTTD1 for paralogs About GeneDecksing

2 Pseudogenes.org Pseudogenes for FYTTD1
PGOHUM00000244342 PGOHUM00000236288

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 3 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs189063222^1,2		--	197478600(+)	`TACCTA/GCCAGG`	3	--	int¹		0	--	--	--	--
rs145253794^1,2	C,	--	197478737(+)	`AATTA-/AATT AATTA`	3	--	int¹		0	--	--	--	--
rs12486112^1,2	C,A,H,	--	197478777(+)	`TGGCTC/TTGTCG`	3	--	int¹		2		NA	122
rs180906900^1,2		--	197478897(+)	`GCCAGC/TGCTGG`	3	--	int¹		0	--	--	--	--
rs112701523^1,2		--	197478938(+)	`GACAGG/AGTTTC`	3	--	int¹		1		CSA	2
rs187008225^1,2		--	197478954(+)	`GTTGGA/CCAGGC`	3	--	int¹		0	--	--	--	--
rs190854177^1,2		--	197479001(+)	`CTTGGC/TCTCCC`	3	--	int¹		0	--	--	--	--
rs60224134^1,2	F,	--	197479110(+)	`GCATGG/AAATCC`	3	--	int¹		1		WA	118
rs183442917^1,2		--	197479209(+)	`AGAAAC/GGTGAC`	3	--	int¹		0	--	--	--	--
rs111796540^1,2		--	197479254(+)	`ACATTG/AAATGA`	3	--	int¹		1		CSA	2

HapMap Linkage Disequilibrium report for FYTTD1 (197464050 - 197511317 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 4 variations for FYTTD1
4 CNVs: 68570 4370 3473 8440

SABiosciences Cancer Mutation PCR Assays

QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing FYTTD1

DNA2.0 Custom Variant and Variant Library Synthesis for FYTTD1

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

FYTTD1 for disorders About GeneDecksing

1 disease for FYTTD1: About MalaCards

prostatitis

Human Genome Epidemiology (HuGE) Navigator: FYTTD1 (1 document)

Export disorders for FYTTD1 gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
About This Section

PubMed articles for FYTTD1 gene, integrated from 9 sources (see all 18):
(articles sorted by number of sources associating them with FYTTD1)

Utopia: connect your pdf to the dynamic
world of online information

UIF, a new mRNA export adaptor that works together with REF/ALY, requires FACT for recruitment to mRNA. (PubMed id 19836239)^{1, 2, 3} Hautbergue G.M.... Wilson S.A. (2009)
Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. (PubMed id 11230166)^{1, 2} Wiemann S.... Poustka A. (2001)
Initial characterization of the human central proteome. (PubMed id 21269460)² Burkard T.R.... Colinge J. (2011)
System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation. (PubMed id 21406692)² Rigbolt K.T....Blagoev B. (2011)
Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048)¹ Danielsen J.M....Nielsen M.L. (2011)
In vivo identification of sumoylation sites by a signature tag and cysteine-targeted affinity purification. (PubMed id 20388717)² Blomster H.A.... Sistonen L. (2010)
Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle. (PubMed id 18691976)² Daub H.... Mann M. (2008)
The DNA sequence, annotation and analysis of human chromosome 3. (PubMed id 16641997)² Muzny D.M....Gibbs R.A. (2006)
Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)² Olsen J.V....Mann M. (2006)
The LIFEdb database in 2006. (PubMed id 16381901)¹ Mehrle A....Wiemann S. (2006)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section

Entrez Gene: 84248	HGNC: 25407	AceView: DKFZp761B1514	Ensembl:ENSG00000122068	euGenes: HUgn84248
ECgene: FYTTD1	H-InvDB: FYTTD1

(According to HUGE)
About This Section

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
PharmGKB entry for FYTTD1	Pharmacogenomics, SNPs, Pathways

Intellectual Property for FYTTD1 gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

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Patent Information for FYTTD1 gene:
Search GeneIP for patents involving FYTTD1

GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search

(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
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	Browse OriGene Antibodies		OriGene shRNA RFP for FYTTD1
	OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for FYTTD1		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for FYTTD1
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	QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat FYTTD1
	QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing FYTTD1
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Search for Antibodies & Assays

	Regulatory tfbs in FYTTD1 promoter
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Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

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FYTTD1 Proteins, Antibodies, CLIAs, and ELISAs

Search LifeMap BioReagents cell lines for FYTTD1

	Gene Synthesis
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Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FYTTD1

	SwitchGear 3'UTR luciferase reporter plasmids for FYTTD1
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ThermoFisher Antibodies for FYTTD1

Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FYTTD1

GeneCards Homepage - Last full update: 19 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 26 Apr 2013

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Category			VWF (GIFTS: 73) von Willebrand factor
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FYTTD1 Gene

forty-two-three domain containing 1

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FYTTD1 Gene

forty-two-three domain containing 1

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Expression
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Orthologs
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Intellectual Property
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