Aliases for FYB Gene
External Ids for FYB Gene
The protein encoded by this gene is an adapter for the FYN protein and LCP2 signaling cascades in T-cells. The encoded protein is involved in platelet activation and controls the expression of interleukin-2. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2011]
GeneCards Summary for FYB Gene
FYB (FYN Binding Protein) is a Protein Coding gene. Among its related pathways are Ras signaling pathway and Class I MHC mediated antigen processing and presentation. GO annotations related to this gene include receptor binding and protein complex binding. An important paralog of this gene is PRAM1.
UniProtKB/Swiss-Prot for FYB Gene
Acts as an adapter protein of the FYN and LCP2 signaling cascades in T-cells. Modulates the expression of interleukin-2 (IL-2). Involved in platelet activation. Prevents the degradation of SKAP1 and SKAP2. May play a role in linking T-cell signaling to remodeling of the actin cytoskeleton.