Aliases for FXYD2 Gene
External Ids for FXYD2 Gene
Previous Symbols for FXYD2 Gene
This gene encodes a member of the FXYD family of transmembrane proteins. This particular protein encodes the sodium/potassium-transporting ATPase subunit gamma. Mutations in this gene have been associated with Renal Hypomagnesemia-2. Alternatively spliced transcript variants have been described. Read-through transcripts have been observed between this locus and the upstream FXYD domain-containing ion transport regulator 6 (FXYD6, GeneID 53826) locus.[provided by RefSeq, Feb 2011]
GeneCards Summary for FXYD2 Gene
FXYD2 (FXYD Domain Containing Ion Transport Regulator 2) is a Protein Coding gene. Diseases associated with FXYD2 include autosomal dominant primary hypomagnesemia with hypocalciuria and hypomagnesemia-2, renal. Among its related pathways are Diuretics Pathway, Pharmacodynamics and Myometrial Relaxation and Contraction Pathways. GO annotations related to this gene include transporter activity and sodium:potassium-exchanging ATPase activity.
UniProtKB/Swiss-Prot for FXYD2 Gene
May be involved in forming the receptor site for cardiac glycoside binding or may modulate the transport function of the sodium ATPase