FXR1 Gene
protein-coding GIFtS: 57
GCID: GC03P180585
|
|
fragile X mental retardation, autosomal homolog 1
| |
Aliases
for FXR1 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Fragile X Mental Retardation, Autosomal Homolog 11 2 | | HFXR1p1 | | FXR1P2 | | Fragile X Mental Retardation Syndrome-Related Protein 12 |
Export aliases for FXR1 gene to outside databasesPrevious GC identifers: GC03P177391 GC03P181474 GC03P182032 GC03P181951 GC03P182113 GC03P178034 |
Summaries
for FXR1 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for FXR1:
The protein encoded by this gene is an RNA binding protein that interacts with the functionally-similar proteins FMR1and FXR2. These proteins shuttle between the nucleus and cytoplasm and associate with polyribosomes, predominantlywith the 60S ribosomal subunit. Three transcript variants encoding different isoforms have been found for this gene.(provided by RefSeq, Jul 2008)
UniProtKB/Swiss-Prot: FXR1_HUMAN, P51114Function: RNA-binding protein required for embryonic and postnatal development of muscle tissue. May regulateintracellular transport and local translation of certain mRNAs (By similarity)
Gene Wiki entry for FXR1
|
Genomic Views
for FXR1 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000003.11 NC_018914.1 NT_005612.16
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the FXR1 gene promoter:
GR RP58 SREBP-1c USF2 SREBP-1b Arnt SREBP-1a COMP1 GR-alpha ATF6
Other transcription factors
Search SABiosciences Chromatin IP Primers for FXR1
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat FXR1 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 3q28 Ensembl cytogenetic band: 3q26.33 HGNC cytogenetic band: 3q28FXR1 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 3 GeneLoc Exon Structure GeneLoc location for GC03P180585: view genomic region
(about GC identifiers)
Start:
|
180,585,929 bp from pter |
End:
|
180,700,541 bp from pter |
Size:
|
114,613 bases |
Orientation:
|
plus strand |
|
Proteins
for FXR1 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: FXR1_HUMAN, P51114 (See
protein sequence)Recommended Name: Fragile X mental retardation syndrome-related protein 1 Size: 621 amino acids; 69721 Da
Subunit: Interacts with FMR1 and FXR2. Interacts with TDRD3, and with CYFIP2 but not with CYFIP1
Subcellular location: Cytoplasm
3 PDB 3D structures from  and Proteopedia  for FXR1:2CPQ (3D)
3KUF (3D)
3O8V (3D)
Secondary accessions: A8K9B8 Q7Z450 Q8N6R8Alternative splicing: 3 isoforms: P51114-1 P51114-2 P51114-3 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for FXR1: NX_P51114
Post-translational modifications:
Arg-445 is dimethylated, probably to asymmetric dimethylarginine1
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_P51114
FXR1 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (3 alternative transcripts):
NP_001013456.1 NP_005078.2 NP_001013457.1
ENSEMBL proteins: ENSP00000419793 ENSP00000417125 ENSP00000418724 ENSP00000350170 ENSP00000307633 ENSP00000419047 ENSP00000420643 ENSP00000420515 ENSP00000388828 ENSP00000419933 ENSP00000418097 ENSP00000417513 ENSP00000418027
Human Recombinant Protein Products:
Gene Ontology (GO): 5 cellular component terms (GO ID links to tree view): About this table
FXR1 for ontologies About GeneDecksing
FXR1 Antibody Products:
Assay Products for FXR1: |
Protein
Domains /
Families
for FXR1 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
FXR1 for domains About GeneDecksing
4 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry P51114ProtoNet protein and cluster: P51114 3 Blocks protein families: IPB004087 KH domain IPB004088 KH IPB008395 Agenet
UniProtKB/Swiss-Prot: FXR1_HUMAN, P51114Domain: The tandem Tudor domains preferentially recognize trimethylated histone peptidesSimilarity: Belongs to the FMR1 familySimilarity: Contains 2 Agenet-like domainsSimilarity: Contains 2 KH domains |
Function
for FXR1 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: FXR1_HUMAN, P51114Function: RNA-binding protein required for embryonic and postnatal development of muscle tissue. May regulateintracellular transport and local translation of certain mRNAs (By similarity) Genatlas biochemistry entry for FXR1:cytoplasmic RNA binding protein (70kDa) homologous to FMR1 and FXR2 (see symbols),homodimerizing and heterodimerizingwith them,expressed in fetal and adult brain testis,putative target for the autoimmune response,with severalalternatively spliced isoforms
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for FXR1 (see all 7)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for FXR1 (see all 3)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 3): FXR1 (NM_005087) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for FXR1 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FXR1 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FXR1 |
Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view): About this table
FXR1 for ontologies About GeneDecksing
Animal Models:
Mouse knock-out Fxr1tm1.2Dln for FXR1
11 MGI mutant phenotypes (inferred from 3 alleles ) (MGI details for Fxr1):
FXR1 for phenotypes About GeneDecksing
|
Pathways & Interactions
for FXR1 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Neuroscience | | | 2 | Translational Control | |
Pathway sources
See GeneCards unified pathways
Show all pathways
2 
Cell Signaling Technology (CST) Pathways for FXR1
FXR1 for pathways About GeneDecksing
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for FXR1
STRING Interaction
Network Preview (showing 5 interactants - click image to see 19)
5/102 Interacting proteins for FXR1 (P511142, 3 ENSP000003501704) via UniProtKB, MINT, STRING, and/or I2D (see all 102)About this table
Gene Ontology (GO): 4 biological process terms (GO ID links to tree view): About this table
FXR1 for ontologies About GeneDecksing
|
Drugs & Compounds
for FXR1 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for FXR1
Search CenterWatch for drugs/clinical trials and news about FXR1
|
Transcripts
for FXR1 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for FXR1 gene (3 alternative transcripts): NM_001013438.2 NM_005087.3 NM_001013439.2 Unigene Cluster for FXR1: Fragile X mental retardation, autosomal homolog 1 Hs.478407 [show with all ESTs]Unigene Representative Sequence: NM_00101343918/22 Ensembl transcripts including schematic representations, and UCSC links where relevant (see all 22): ENST00000469882 ENST00000484790 ENST00000465551(uc011bqi.2) ENST00000357559(uc003fkq.3 uc003fkr.3 uc011bqj.2 uc003fks.3 uc011bqk.2 uc011bql.2)
ENST00000305586(uc003fkp.3) ENST00000475315 ENST00000491674 ENST00000491062
ENST00000468861 ENST00000479176 ENST00000445140 ENST00000472339 ENST00000484958
ENST00000480918 ENST00000484042 ENST00000461801 ENST00000473375 ENST00000461044
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for FXR1 (see all 7)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for FXR1 (see all 3)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 3): FXR1 (NM_005087) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for FXR1 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FXR1 |
Additional cDNA sequence: AF075028.1 AK225334.1 AK292633.1 AK294603.1 AK297254.1 AK297331.1 AK302197.1 AY341428.1 BC010382.1 BC028983.1 U25165.1 X90874.1 24/31 DOTS entries (see all 31): DT.101956646 DT.120924032 DT.91654486 DT.100692495 DT.110894 DT.456405 DT.100826538 DT.100029873 DT.110219 DT.414018 DT.100826544 DT.91646764 DT.100826537 DT.100826534 DT.92445716 DT.95351112 DT.100826542 DT.120924093 DT.40128322 DT.120923965 DT.120924000 DT.120924013 DT.120924081 DT.40128116 24/452 AceView cDNA sequences (see all 452): BE018414 BE223048 Z38162 AI879339 AA662179 BQ018942 BQ719137 AA055090 AI431767 AU126906 AL040900 AI221936 AA330376 CF552812 AA325701 BG576837 BU615207 BX111910 BM980262 X90874 AA443860 BX477555 BF223903 AW271355
GeneLoc Exon Structure
5/13 Alternative Splicing Database (ASD) splice patterns (SP) for FXR1 (see all 13) About this scheme
| ExUns: | 1a | · | 1b | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5a | · | 5b | ^ | 6a | · | 6b | ^ | 7 | ^ | 8a | · | 8b | ^ | 9 | ^ | 10 | ^ | 11a | · | 11b | · | 11c | ^ | 12 | ^ | 13 | ^ | 14a | · | 14b | ^ | 15a | · | 15b | ^ | 16a | · | 16b | ^ | 17a | · |
|---|
|
| SP1: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | - | | | | | | | | | | | | | | | | | | | | | | | | |
| SP2: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | - | | | | | | | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | - | | | | | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | - | | | | | | | | | | | | | | | | - | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | - | | | | | | | |
| ExUns: | 17b | ^ | 18a | · | 18b |
|---|
|
| SP1: | | | | | | | |
| SP2: | | | | | | | |
| SP3: | | | | | | | |
| SP4: | | | | | | | |
| SP5: | | | | | | |
ECgene alternative splicing isoforms for FXR1
|
Expression
for FXR1 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| FXR1 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TTAGTCTTCA
About this image
See FXR1 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for FXR1
SOURCE GeneReport for Unigene cluster: Hs.478407
UniProtKB/Swiss-Prot: FXR1_HUMAN, P51114Tissue specificity: Expressed in all tissues examined including heart, brain, kidney and testis
SABiosciences Custom PCR Arrays for FXR1
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for FXR1
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat FXR1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat FXR1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat FXR1 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FXR1 |
Orthologs
for FXR1 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for FXR1 gene from 6/20 species (see all 20) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
mouse
(Mus musculus) |
Mammalia |
Fxr11 , 5 |
fragile X mental retardation gene 1, autosomal homolog1, 5 |
94.95(n)1
98.07(a)1 |
|
3 (16.41 cM)5
143591 NM_001113188.11 NP_001106659.11
340200795 |
chicken
(Gallus gallus) |
Aves |
FXR11 |
fragile X mental retardation, autosomal homolog 1 |
82.93(n)
92.43(a) |
|
424968 NM_001012601.1 NP_001012619.1 |
lizard
(Anolis carolinensis) |
Reptilia |
FXR16 |
-- |
84(a) |
1 ↔ 1 |
3(1479847-1498410) |
African clawed frog
(Xenopus laevis) |
Amphibia |
BC043638.12 |
-- |
82.34(n) |
|
BC043638.1 |
zebrafish
(Danio rerio) |
Actinopterygii |
wufd18c102 |
wufd18c10 |
74.67(n) |
|
327220 BC055557.1 |
fruit fly
(Drosophila melanogaster) |
Insecta |
Fmr11 , 3 |
negative regulation of translation mRNA
binding3
CG6203-PA1 |
48(a)3
49.54(n)1
44.59(a)1 |
|
375281 NM_137801.41 NP_611645.11 |
ENSEMBL Gene Tree for FXR1 (if available)
TreeFam Gene Tree for FXR1 (if available) |
Paralogs
for FXR1 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for FXR1 gene
- FMR12 FXR22
2 SIMAP similar genes for FXR1 using alignment to 12 protein entries: FXR1_HUMAN (see all proteins):FXR2 FMR1
FXR1 for paralogs About GeneDecksing
1 Pseudogenes.org Pseudogene for FXR1
PGOHUM00000239421
|
Genomic Variants
for FXR1 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 3 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for FXR1 (180585929 - 180700541 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for FXR1: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing FXR1 |
|
Disorders
/ Diseases
for FXR1 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Novoseek,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
FXR1 for disorders About GeneDecksing
OMIM gene information: 600819
OMIM disorders: --
11  diseases for FXR1: About MalaCardsmental retardation syndrome fragile x syndrome facioscapulohumeral muscular dystrophy muscular dystrophy
intellectual disability squamous cell carcinoma bipolar disorder colon cancer
myeloma carcinoma neuronitis
2 diseases from the University of Copenhagen DISEASES database for FXR1:Fragile X syndrome Intellectual disability 2 Novoseek disease relationships for FXR1 gene About this table
| Disease |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| fragile x syndrome |
81.2 |
2 |
10446811 (1), 18628314 (1) |
| mental retardation |
69.1 |
5 |
7489725 (2), 18628314 (1), 7781595 (1) |
Export disorders for FXR1 gene to outside databases
|
Publications
for FXR1 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for FXR1 gene, integrated from 9 sources (see all 65):
(articles sorted by number of sources associating them with FXR1) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- FXR1, an autosomal homolog of the fragile X mental retardation gene. (PubMed id 7781595)1, 2, 3, 9 Siomi M.C....Dreyfuss G. (1995)
- The fragile-X-related gene FXR1 is a human autoantigen processed during apoptosis. (PubMed id 9642279)1, 3, 9 Bolivar J....Valdivia M.M. (1998)
- Structural studies of the tandem Tudor domains of fra gile X mental retardation related proteins FXR1 and FXR2. (PubMed id 21072162)1, 2 Adams-Cioaba M.A....Min J. (2010)
- Tdrd3 is a novel stress granule-associated protein interacting with the Fragile-X syndrome protein FMRP. (PubMed id 18664458)1, 2 Linder B.... Fischer U. (2008)
- Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)1, 2 Olsen J.V....Mann M. (2006)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Highly conserved 3' UTR and expression pattern of FXR1 points to a divergent gene regulation of FXR1 and FMR1. (PubMed id 8634689)1, 9 Coy J.F.... Poustka A. (1995)
- Comparative genomic sequence analysis of the FXR gene family: FMR1, FXR1, and FXR2. (PubMed id 11735223)1, 9 Kirkpatrick L.L....Nelson D.L. (2001)
- Alteration of expression of muscle specific isoforms of the fragile X related protein 1 (FXR1P) in facioscapulohumeral muscular dystrophy patients. (PubMed id 18628314)1, 9 Davidovic L....Bardoni B. (2008)
- Two members of the Fxr gene family, Fmr1 and Fxr1, are differentially expressed in Xenopus tropicalis. (PubMed id 15968590)1, 9 Blonden L....Willemsen R. (2005)
|
External Searches for FXR1 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing FXR1 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing FXR1 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing FXR1 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for FXR1 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for FXR1 gene:
Search GeneIP for patents involving FXR1
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for FXR1 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
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| | |  | OriGene Antibodies for FXR1 | | OriGene shRNA RFP for FXR1 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for FXR1 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for FXR1 | | | OriGene Protein Over-expression Lysate for FXR1 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for FXR1 | | OriGene 3'-UTR Clone for FXR1 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for FXR1 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for FXR1 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for FXR1 | | OriGene Custom Protein Services for FXR1 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat FXR1 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing FXR1 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat FXR1 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat FXR1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat FXR1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat FXR1 |
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| | Antibodies & Assays for FXR1 |
| | | | Search Tocris compounds for FXR1 |
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 | | | FXR1 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FXR1 |
|  |  |  | | | | ThermoFisher Antibodies for FXR1 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FXR1 |
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