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KDSR Gene

protein-coding GIFtS: 51

GC18M059145

3-ketodihydrosphingosine reductase
(Previous name: follicular lymphoma variant translocation 1 )
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database
(Previous symbol: FVT1)

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc , and/or ⁷Ensembl, ⁸miRBase)
About This Section

Aliases
DHSR ^¹, ²
EC 1.1.1.102 ^³
FLJ36555 ^²
FLJ92680 ^²
FVT-1 ^³
FVT1 ^², ³
SDR35C1 ^¹, ²

Descriptions
3-dehydrosphinganine reductase ^², ³
3-ketodihydrosphingosine reductase ^²
Follicular variant translocation protein 1 ^³
KDS reductase ^², ³
follicular lymphoma variant translocation 1 ^¹, ²
short chain dehydrogenase/reductase family 35C, member 1 ^²

External Ids
HGNC: 4021¹
Entrez Gene: 2531²
UniProtKB: Q06136³
Ensembl: ENSG00000119537⁷

Search outside databases for aliases for KDSR gene

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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EntrezGene summary for KDSR:

The protein encoded by this gene catalyzes the reduction of 3-ketodihydrosphingosine to

dihydrosphingosine. The putative active site residues of the encoded protein are found on the

cytosolic side of the endoplasmic reticulum membrane. A chromosomal rearrangement involving this

gene is a cause of follicular lymphoma, also known as type II chronic lymphatic leukemia. The

mutation of a conserved residue in the bovine ortholog causes spinal muscular atrophy. [provided

by RefSeq]

UniProtKB/Swiss-Prot: KDSR_HUMAN, Q06136

Function: Catalyzes the reduction of 3-ketodihydrosphingosine (KDS) to dihydrosphingosine (DHS)

Gene Wiki entry for KDSR (FVT1)

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
About This Section

Genomic View:

UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 18q21.3 Ensembl cytogenetic band: 18q21.33 HGNC cytogenetic band: 18q21

KDSR Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 18 GeneLoc Exon Structure

GeneLoc location for GC18M059145: (about GC identifiers)

Start:	59,145,951 bp from pter
End:	59,185,486 bp from pter
Size:	39,536 bases
Orientation:	minus strand

RefSeq DNA sequence:

NC_000018.8 NT_025028.13

(According to ¹UniProtKB, and/or Ensembl, Phosphorylation sites according to ²Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
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UniProtKB/Swiss-Prot: KDSR_HUMAN, Q06136 (See protein sequence)

Recommended Name: 3-ketodihydrosphingosine reductase precursor

Size: 332 amino acids; 36187 Da

Subcellular location: Endoplasmic reticulum membrane; Multi-pass membrane protein

REFSEQ proteins: NP_002026.1

ENSEMBL proteins:

ENSP00000312939 ENSP00000385083

Human Recombinant Proteins

	Browse Drug Discovery Central at Invitrogen for human recombinant proteins
	Browse Purified and Recombinant Proteins at Millipore
	Browse Human Recombinant Proteins at Sigma-Aldrich
	Browse R&D Systems for human recombinant proteins
	Browse recombinant and purified proteins available from Enzo Life Sciences
	Recombinant Proteins from Abcam (FVT1)
	Human Recombinant Proteins from Abnova (FVT1)

Browse Origene for full length recombinant human proteins expressed in human HEK293 cells

5 Gene Ontology (GO) cellular component terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005615	extracellular space	TAS	8417785
GO:0005783	endoplasmic reticulum	IEA	--
GO:0005789	endoplasmic reticulum membrane	IEA	--
GO:0016020	membrane	IEA	--
GO:0016021	integral to membrane	IEA	--

About this table

Antibodies for KDSR:

	Browse Antibodies Central at Invitrogen
	Browse Millipore's Extensive Line of Mono- and Polyclonal Antibodies
	Sigma-Aldrich Antibodies for KDSR
	Browse R&D Systems for Antibodies
	Antibodies from Abcam (FVT1), each with their Abpromise^SM
	Monoclonal and Polyclonal Antibodies from Abnova (FVT1)
	Novus Biologicals Antibody for KDSR

Assays for KDSR:

	Browse Invitrogen for biochemical assays
	Browse Kits and Assays available from Millipore
	Browse R&D Systems for biochemical assays
	Browse biochemical assays available from Enzo Life Sciences

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

Graphical View of Domain Structure for InterPro Entry Q06136

ProtoNet protein and cluster: Q06136

2 Blocks protein families:

IPB002198 Short-chain dehydrogenase/reductase SDR

IPB002347 Glucose/ribitol dehydrogenase family signature

UniProtKB/Swiss-Prot: KDSR_HUMAN, Q06136

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family

(According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
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Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (KDSR)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (FVT1)

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_002035

Applied Biosystems Silencer® siRNAs for KDSR

Sigma-Aldrich siRNA and siRNA Panels for KDSR

Sigma-Aldrich shRNA for KDSR

Explore Sigma-Aldrich super-pooled esiRNAs

Clones:		Invitrogen Clones for KDSR
		Browse Clones for the Expression of Recombinant Proteins Available from Millipore

OriGene GFP tagged cDNA clone in CMV expression vector: NM_002035
Myc/DDK tagged cDNA clone in CMV expression vector: NM_002035
untagged cDNA clone in CMV expression vector: NM_002035

Primers:

Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers

OriGene genome-wide validated SYBR primer pairs: NM_002035

UniProtKB/Swiss-Prot: KDSR_HUMAN, Q06136

Function: Catalyzes the reduction of 3-ketodihydrosphingosine (KDS) to dihydrosphingosine (DHS)

Catalytic activity: Sphinganine + NADP(+) = 3-dehydrosphinganine + NADPH

Enzyme Number (IUBMB): EC 1.1.1.102

3 Gene Ontology (GO) molecular function terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005488	binding	IEA	--
GO:0016491	oxidoreductase activity	IEA	--
GO:0047560	3-dehydrosphinganine reductase activity	IEA	--

About this table

(Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to ¹UniProtKB, ²MINT, and/or ³STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
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1 Sigma-Aldrich "Your Favorite Gene" Pathway for KDSR (Your Favorite Gene powered by Ingenuity)

Sphingolipid Metabolism

GeneDecks KDSR for the pathways selected above

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UniProtKB/Swiss-Prot: KDSR_HUMAN, Q06136

Pathway: Lipid metabolism; sphingolipid metabolism

5/14 Interacting proteins for KDSR (ENSP00000312939³) via UniProtKB, MINT, and/or STRING (see all 14 )

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
SPTLC1	ENSP00000262554³	STRING (score=.927)
SPTLC2	ENSP00000216484³	STRING (score=.927)
ACER3	ENSP00000278544³	STRING (score=.899)
ASAH1	ENSP00000371152³	STRING (score=.899)
PPAP2A	ENSP00000264775³	STRING (score=.899)

About this table

1 Gene Ontology (GO) biological process term (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0055114	oxidation reduction	IEA	--

About this table

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
About This Section

Browse drugs & compounds from Enzo Life Sciences

Browse Small Molecules at Sigma-Aldrich

Browse Tocris compounds for KDSR

(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Invitrogen, Millipore, and/or Abnova,
siRNAs from Applied Biosystems, Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene,
Tagged/untagged cDNA clones from OriGene,
Expression Assays from Applied Biosystems)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (KDSR)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (FVT1)

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_002035

Sigma-Aldrich siRNA and siRNA Panels for KDSR

Sigma-Aldrich shRNA for KDSR

Explore Sigma-Aldrich super-pooled esiRNAs

Applied Biosystems Silencer® siRNAs:

NM_002035

REFSEQ mRNAs for KDSR gene:

NM_002035.2

Applied Biosystems TaqMan ® Gene Expression Assays:

NM_002035

              OriGene GFP tagged cDNA clone in CMV expression vector: NM_002035
                                 Myc/DDK tagged cDNA clone in CMV expression vector: NM_002035
                                 untagged cDNA clone in CMV expression vector: NM_002035

Additional cDNA sequence:

AF086045.1 AK025120.1 AK093874.1 AK297670.1 AK312360.1 BT006782.1 CR594682.1 X63657.1

13 DOTS entries:

DT.317085 DT.92437163 DT.428248 DT.92062831 DT.97816320 DT.86848376 DT.70105324 DT.100801515

DT.100801521 DT.40278781 DT.95375235 DT.75126660 DT.95103117

24/251 AceView cDNA sequences (see all 251 ):

AA226862 AA314211 AU121524 BE018271 BF478064 N30152 BX448427 AI811325

NM_002035 AA047249 BX370283 AU155043 BM979494 CD516284 AA099731 CD676126

AA745021 AA845580 BE301748 AK093874 BX480324 AA400780 BC008797 AI418119

Unigene Cluster for KDSR:

3-ketodihydrosphingosine reductase

Hs.74050 [show with all ESTs]

Unigene Representative Sequence: NM_002035

GeneLoc Exon Structure

5/6 Alternative Splicing Database (ASD) splice patterns (SP) for KDSR (see all 6 )

ExUns:	1	^	2	^	3	^	4	^	5a	·	5b	·	5c	^	6	^	7	^	8	^	9a	·	9b	^	10	^	11	^	12a	·	12b	·	12c
SP1:			-										-						-		-
SP2:													-						-		-						-
SP3:
SP4:			-
SP5:																					-

About this scheme

ECgene alternative splicing isoforms for KDSR

2 Ensembl transcripts including schematic representations:

ENST00000326575 ENST00000406396

(Experimental results according to ¹GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to ²GeneAnnot , ³GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Expression Assays from Applied Biosystems )
About This Section

KDSR expression in normal and diseased human tissues

Applied Biosystems TaqMan ® Gene Expression Assays for KDSR

¹ / ²

10 probe-sets matching KDSR gene

Affymetrix probe-set	Array	# genes	Sensitivity	Specificity	Correlation	Length	Gb_Accession	Consensus	Uniqueness	Score	Rank
Affymetrix probe-set	Array	GeneAnnot data			GeneNote data		GeneTide data
80607_i_at²	U95-E	1	1.00	1.00	0.94	1.10	--	--	--	--	--
36120_at²	U95-A	1	1.00	1.00	0.79	1.01	--	--	--	--	--
44592_at²	U95-B	1	1.00	1.00	0.95	1.11	--	--	--	--	--
56732_at²	U95-B	1	1.00	1.00	0.90	0.88	--	--	--	--	--
80610_r_at²	U95-E	1	1.00	1.00	0.77	0.92	--	--	--	--	--
229850_at²	U133-B	1	1.00	1.00	--	--	--	--	--	--	--
202419_at²	U133-A	1	1.00	1.00	--	--	--	--	--	--	--
229850_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--
1558279_a_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--
202419_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--

GeneDecks KDSR for binary patterns associated with the probe-sets selected above

About GeneDecksing

About this table

Data from

(Publications) and GNF BioGPS
About these images
About these images

CGAP SAGE TAG: --

SOURCE GeneReport for Unigene cluster: Hs.74050
UniProtKB/Swiss-Prot: KDSR_HUMAN, Q06136
Tissue specificity: Expressed in all tissues examined. Highest expression in placenta. High
expression in lung, kidney, stomach and small intestine, low expression in heart, spleen and
skeletal muscle. Weakly expressed in normal hematopoietic tissues. Higher expression in some
T-cell malignancies and PHA-stimulated lymphocytes

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD and/or ⁵MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
About This Section

Orthologs for KDSR gene from 5/15 species (see all 15 )

Organism	Gene	Locus	Description	Human Similarity	NCBI accessions
dog (Canis familiaris)	KDSR¹	--	3-ketodihydrosphingosine reductase	90.69(n) 95.22(a)	609655 XM_846955.1 XP_852048.1
chimpanzee (Pan troglodytes)	KDSR¹	--	3-ketodihydrosphingosine reductase	100(n) 100(a)	738461 XM_001146146.1 XP_001146146.1
cow (Bos taurus)	KDSR¹	--	3-ketodihydrosphingosine reductase	88.62(n) 93.05(a)	505558 NM_001045919.1 NP_001039384.1
rat (Rattus norvegicus)	Kdsr¹	--	3-ketodihydrosphingosine reductase	87.35(n) 92.77(a)	360833 XM_341106.3 XP_341107.1
mouse (Mus musculus)	Kdsr^{1, 5}	1⁵	3-ketodihydrosphingosine reductase^{1, 5}	87.95(n)¹ 92.77(a)¹	70750¹ NM_027534.1¹ NP_081810.1¹ AK018155⁵ AK035049⁵ (see all 14)

About this table Species with no ortholog for KDSR

ENSEMBL Gene Tree for KDSR

(Paralogs according to ¹HomoloGene
and ²Ensembl, Pseudogenes according to ³Pseudogene.org)
About This Section

Paralogs for KDSR gene

HSD11B1L² HSD11B1²

(According to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
About This Section

10/222 NCBI SNPs in KDSR are shown (see all 222 )
(Click for Applied Biosystems TaqMan ® Genotyping Assay) (see all 67)

AB	SNP ID	Valid	Chr 18 pos	Sequence	Recs	AA Chg	Type	More	Recs	Allele freq	Pop	Total sample	More
AB	Genomic Data				Transcription Data				Allele Frequencies
				--	--	--		--	--				--
	rs698708^1,2	A,C,F,H,O	59146241(-)	`AAGTAC/GCTGCC`	1	--	ut3¹		17		NA EA NS MN EU WA	1112
	rs2849383^1,2	A,C,F,H	59148361(+)	`TAAAGT/ACAAGA`	1	--	ut3¹		12		NA EA EU WA	2535
	rs6810^1,2	A,C,F,H	59149381(-)	`TCTGCT/CGCTGG`	1	--	ut3¹ ese³		6		MN EU EA WA	790
	rs10460159^1,2	A,C,F,H	59147340(+)	`AAAAAT/CAGAAT`	1	--	ut3¹		4		EU EA WA	416
--	rs2850766^1,2	A,C,H	59149547(+)	`agagaG/Cagaga`	1	--	ut3¹ trp³		1		EU	120
	rs11663788^1,2	C,F,H	59148758(+)	`TAGCAT/CGTGGT`	1	--	ut3¹		8		EU EA WA NA	776
	rs428356^1,2	F,H	59185853(-)	`AAGCCG/CAGGGC`	1	--	ng3¹		9		EA NA MN EU WA	744
--	rs506397^1,2	A,C	59186683(-)	`gcaagA/Tttata`	1	--	ng3¹ tfbs³		0	--	--	--	--
	rs2850765^1,2	C,F	59148429(+)	`TTGTAT/CAGAGT`	1	--	ut3¹		3		NA EA	252
--	rs2551407^1,2	A,C	59146718(+)	`acaggC/Tgcctg`	1	--	ut3¹		0	--	--	--	--

About this table

HapMap Linkage Disequilibrium images for KDSR (up to first 250kb)

(in which this Gene is Involved, According to OMIM, UniProtKB, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
About This Section

OMIM: 136440

UniProtKB/Swiss-Prot: KDSR_HUMAN, Q06136

A chromosomal aberration involving KDSR is a cause of follicular lymphoma; also known as

type II chronic lymphatic leukemia. Translocation t(2;18)(p11;q21) with a Ig J kappa chain region

Human Genome Epidemiology Navigator: KDSR (0 documents)

(Possibly Related Articles in Doctor's Guide)
About This Section

(in PubMed. Associations of this gene to articles via ¹Novoseek, ²HGNC, ³Entrez Gene, ⁴UniProtKB/Swiss-Prot, ⁵UniProtKB/TrEMBL, ⁶GAD, and/or ⁷PharmGKB)
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10/12 PubMed articles for KDSR gene (see all 12 ):

FVT-1 is a mammalian 3-ketodihydrosphingosine reductase with an active site that faces the cytosolic side of the endoplasmic reticulum membrane. (PubMed id 15328338)^{1, 2, 3, 4} Kihara A. and Igarashi Y. (2004)
FVT-1, a novel human transcription unit affected by variant translocation t(2;18)(p11;q21) of follicular lymphoma. (PubMed id 8417785)^{1, 2, 3, 4} Rimokh R.... Magaud J.-P. (1993)
A missense mutation in the 3-ketodihydrosphingosine reductase FVT1 as candidate causal mutation for bovine spinal muscular atrophy. (PubMed id 17420465)^{1, 2, 3} Krebs S....Forster M. (2007)
The SDR (short-chain dehydrogenase/reductase and related enzymes) nomenclature initiative. (PubMed id 19027726)^{2, 3} Persson B....Oppermann U. (2008)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{3, 4} Gerhard D.S....Malek J. (2004)
B-cell non-Hodgkin's lymphoma cell line (Karpas 1106) with complex translocation involving 18q21.3 but lacking BCL2 rearrangement and expression. (PubMed id 7949096)^{1, 3} Nacheva E....Bevan P.C. (1994)
Candidate screening of the bovine and feline spinal muscular atrophy genes reveals no evidence for involvement in human motor neuron disorders. (PubMed id 18395445)³ Parkinson N.J....Talbot K. (2008)
Expression of the follicular lymphoma variant translocation 1 gene in diffuse large B-cell lymphoma correlates with subtype and clinical outcome. (PubMed id 19019774)³ Czuchlewski D.R....Cesarman E. (2008)
[Assessment of five thrombophilic genetic polymorphisms among couples with habitual abortion] (PubMed id 16711541)³ Quintero-Ramos A....Rivas F. (2006)
Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)³ Ota T....Sugano S. (2004)

(in PubMed, OMIM, and NCBI Bookshelf)
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		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
About This Section

Entrez Gene: 2531	HGNC: 4021	AceView: FVT1	Ensembl:ENSG00000119537	euGenes: HUgn2531
ECgene: KDSR	H-InvDB: KDSR

(According to HUGE)
About This Section

(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Licensable Technologies for KDSR
(Available from WIS Yeda, Salk, Tufts)

About This Section

(Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
Enzo Life Sciences, and/or Tocris Bioscience)
About This Section

Products for KDSR:

TaqMan ® Gene Expression Assays

TaqMan ® Genotyping Assays

Free SNP selection tool

Invitrogen iPath Pathways	Invitrogen BLOCK-iT™ RNAi
Invitrogen Antibodies	Invitrogen Assays
Invitrogen Clones	Invitrogen Q-PCR Products
Invitrogen Human Recombinant Kinases	Invitrogen Custom Antibody and Peptide Service
Invitrogen Proteins / Assays / Screening Services	Search Invitrogen catalog for KDSR-related products

	Millipore Custom Antibody & Bulk Services
	Millipore Preclinical / Clinical Development Services
	Millipore Immunoassay Services
	Millipore Target Screening & Profiling Services

	Predesigned and custom siRNAs for KDSR		Antibodies for KDSR
	Explore super-pooled esiRNAs		Browse proteins at Sigma-Aldrich
	Lentivirus-delivered shRNAs for KDSR		Browse small molecules at Sigma-Aldrich
	"Your Favorite Gene" Pathways		feedback

	Antibodies		Primer Pairs
	Cell Culture Products		ELISAs
	Flow Cytometry Kits		Protease Activity Assays & Reagents
	Cell Selection/Detection Kits & Reagents		ELISA/Assay Development Kits & Reagents
	Multiplex/Array Assay Kits & Reagents		ELISpot Kits & Development Modules
	Recombinant & Natural Proteins

	Recombinant Proteins (FVT1)
	Antibodies (FVT1)
	Chimera RNAi (FVT1)
	Custom Service for Mouse Mab
	Custom Service for Rabbit Pab from Full-length Protein

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	Antibodies (FVT1)

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KDSR Gene

protein-coding GIFtS: 51

Aliases &
Descriptions
for KDSR

Summaries
for KDSR

Genomic Location
for KDSR

Proteins
for KDSR

Protein Domains/
Families
for KDSR

Gene Function
for KDSR

Pathways & Interactions
for KDSR

Drugs & Compounds
for KDSR

Transcripts
for KDSR

Expression
for KDSR

Orthologs
for KDSR

Paralogs
for KDSR

SNPs/Variants
for KDSR

Disorders & Mutations
for KDSR

Medical News
for KDSR

Publications
for KDSR

Search for KDSR

Genome Databases showing KDSR

Other Databases showing KDSR

Specialized Databases showing KDSR

Licensable Technologies
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Services
for KDSR

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

KDSR Gene

protein-coding GIFtS: 51

Aliases & Descriptionsfor KDSR

Summariesfor KDSR

Genomic Locationfor KDSR

Proteinsfor KDSR

Protein Domains/Familiesfor KDSR

Gene Functionfor KDSR

Pathways & Interactionsfor KDSR

Drugs & Compoundsfor KDSR

Transcriptsfor KDSR

Expression for KDSR

Orthologsfor KDSR

Paralogsfor KDSR

SNPs/Variantsfor KDSR

Disorders & Mutationsfor KDSR

Medical Newsfor KDSR

Publicationsfor KDSR

Search for KDSR

Genome Databases showing KDSR

Other Databases showing KDSR

Specialized Databases showing KDSR

Licensable Technologiesfor KDSR

Servicesfor KDSR

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Aliases &
Descriptions
for KDSR

Summaries
for KDSR

Genomic Location
for KDSR

Proteins
for KDSR

Protein Domains/
Families
for KDSR

Gene Function
for KDSR

Pathways & Interactions
for KDSR

Drugs & Compounds
for KDSR

Transcripts
for KDSR

Expression
for KDSR

Orthologs
for KDSR

Paralogs
for KDSR

SNPs/Variants
for KDSR

Disorders & Mutations
for KDSR

Medical News
for KDSR

Publications
for KDSR

Licensable Technologies
for KDSR

Services
for KDSR