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FUT9 Gene

protein-coding   GIFtS: 57
GCID: GC06P096463

Fucosyltransferase 9 (Alpha (1,3) Fucosyltransferase)

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Fucosyltransferase 9 (Alpha (1,3) Fucosyltransferase)1 2     EC 2.4.1.-3
Fucosyltransferase IX2 3     FucT-IX3
Galactoside 3-L-Fucosyltransferase2 3     Fucosyltransferase 93
Fuc-TIX2 3     EC 2.4.18
Alpha-(1,3)-Fucosyltransferase 92     EC 2.4.1.658
fucT-IX2     

External Ids:    HGNC: 40201   Entrez Gene: 106902   Ensembl: ENSG000001724617   OMIM: 6068655   UniProtKB: Q9Y2313   

Export aliases for FUT9 gene to outside databases

Previous GC identifers: GC06P096332 GC06P096480 GC06P096509 GC06P096570 GC06P093896


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for FUT9 Gene:
The protein encoded by this gene belongs to the glycosyltransferase family. It is localized to the golgi, and
catalyzes the last step in the biosynthesis of Lewis X (LeX) antigen, the addition of a fucose to precursor
polysaccharides. This protein is one of the few fucosyltransferases that synthesizes the LeX oligosaccharide
(CD15) expressed in the organ buds progressing in mesenchyma during embryogenesis. It is also responsible for the
expression of CD15 in mature granulocytes. A common haplotype of this gene has also been associated with
susceptibility to placental malaria infection. (provided by RefSeq, Nov 2011)

GeneCards Summary for FUT9 Gene:
FUT9 (fucosyltransferase 9 (alpha (1,3) fucosyltransferase)) is a protein-coding gene. Diseases associated with FUT9 include malaria, and cytomegalovirus infection. GO annotations related to this gene include alpha-(1->3)-fucosyltransferase activity and fucosyltransferase activity. An important paralog of this gene is FUT5.

UniProtKB/Swiss-Prot: FUT9_HUMAN, Q9Y231
Function: Transfers a fucose to lacto-N-neotetraose but not to either alpha2,3-sialyl lacto-N-neotetraose or
lacto-N-tetraose. Can catalyze the last step in the biosynthesis of Lewis antigen, the addition of a fucose to
precursor polysaccharides

Gene Wiki entry for FUT9 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000006.12  NC_018917.2  NT_025741.16  
Regulatory elements:
   Regulatory transcription factor binding sites in the FUT9 gene promoter:
         POU2F1   HNF-1   POU2F1a   FOXD3   HNF-1A   Arnt   E47   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidFUT9 promoter sequence
   Search Chromatin IP Primers for FUT9

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat FUT9


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 6q16   Ensembl cytogenetic band:  6q16.1   HGNC cytogenetic band: 6q16

FUT9 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
FUT9 gene location

GeneLoc information about chromosome 6         GeneLoc Exon Structure

GeneLoc location for GC06P096463:  view genomic region     (about GC identifiers)

Start:
96,463,845 bp from pter      End:
96,663,488 bp from pter
Size:
199,644 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: FUT9_HUMAN, Q9Y231 (See protein sequence)
Recommended Name: Alpha-(1,3)-fucosyltransferase 9  
Size: 359 amino acids; 42071 Da
Secondary accessions: Q5T0W4

Explore the universe of human proteins at neXtProt for FUT9: NX_Q9Y231

Explore proteomics data for FUT9 at MOPED

Post-translational modifications: 

  • Glycosylation2 at Asn62, Asn101, Asn153
  • Modification sites at PhosphoSitePlus
  • Selected DME Specific Peptides for FUT9 (Q9Y231) (see all 5)
     FNETTIL  VPVVLGP  FYLSFENS  FSPMESASSVLKMKNFFS 


    See FUT9 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_006572.2  
    ENSEMBL proteins: 
     ENSP00000302599  

    FUT9 Human Recombinant Protein Products:

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    FUT: Fucosyltransferases

    1 InterPro protein domain:
     IPR001503 Glyco_trans_10

    Graphical View of Domain Structure for InterPro Entry Q9Y231

    ProtoNet protein and cluster: Q9Y231

    1 Blocks protein domain: IPB001503 Glycosyl transferase

    UniProtKB/Swiss-Prot: FUT9_HUMAN, Q9Y231
    Similarity: Belongs to the glycosyltransferase 10 family


    FUT9 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: FUT9_HUMAN, Q9Y231
    Function: Transfers a fucose to lacto-N-neotetraose but not to either alpha2,3-sialyl lacto-N-neotetraose or
    lacto-N-tetraose. Can catalyze the last step in the biosynthesis of Lewis antigen, the addition of a fucose to
    precursor polysaccharides

         Genatlas biochemistry entry for FUT9:
    fucosyltransferase 9,alpha (1.3) fucosyltransferase,abundantly expressed in brain and stomach,also detected in
    spleen and peripheral blood leukocytes,mouse Fuc-TIX ortholog,catalyzing the last step of Lewis X synthesis

         Enzyme Numbers (IUBMB): EC 2.4.1.652 EC 2.4.12 EC 2.4.1.-1

         Gene Ontology (GO): 2 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0008417fucosyltransferase activity TAS10386598
    GO:0046920alpha-(1->3)-fucosyltransferase activity TAS11698403
         
    FUT9 for ontologies           About GeneDecksing


    Phenotypes:
         2 MGI mutant phenotypes (inferred from 1 allele(MGI details for Fut9):
     mortality/aging  nervous system 

    FUT9 for phenotypes           About GeneDecksing

    Animal Models:
         MGI mouse knock-out Fut9tm1Nari for FUT9

       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for FUT9
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    miRNA
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    miRTarBase miRNAs that target FUT9:
    hsa-mir-335-5p (MIRT017457)

    Block miRNA regulation of human, mouse, rat FUT9 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate FUT9 (see all 136):
    hsa-miR-579 hsa-miR-361-5p hsa-miR-199a-3p hsa-miR-128 hsa-miR-3921 hsa-miR-4275 hsa-miR-130b hsa-miR-34c-5p
    Browse SwitchGear 3'UTR luciferase reporter plasmids
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FUT9


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    FUT9_HUMAN, Q9Y231: Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein (By similarity).
    Note=Membrane-bound form in trans cisternae of Golgi (By similarity)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    golgi apparatus5
    extracellular2
    endoplasmic reticulum1
    lysosome1
    mitochondrion1

    Gene Ontology (GO): 4 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005794Golgi apparatus TAS11698403
    GO:0016020membrane ----
    GO:0016021integral component of membrane IEA--
    GO:0032580Golgi cisterna membrane IEA--

    FUT9 for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for FUT9 About    
    See pathways by source

    SuperPathContained pathways About
    1Metabolism
    Metabolic pathways0.38
    2Other types of O-glycan biosynthesis
    Other types of O-glycan biosynthesis
    3Glycosphingolipid biosynthesis - lacto and neolacto series
    Glycosphingolipid biosynthesis - lacto and neolacto series
    4Glycosphingolipid biosynthesis - globo series
    Glycosphingolipid biosynthesis - globo series

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways




    4 Kegg Pathways  (Kegg details for FUT9):
        Other types of O-glycan biosynthesis
    Glycosphingolipid biosynthesis - lacto and neolacto series
    Glycosphingolipid biosynthesis - globo series
    Metabolic pathways

    UniProtKB/Swiss-Prot: FUT9_HUMAN, Q9Y231
    Pathway: Protein modification; protein glycosylation


    FUT9 for pathways           About GeneDecksing

        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for FUT9
    Interactions:

        Search GeneGlobe Interaction Network for FUT9

    STRING Interaction Network Preview (showing 5 interactants - click image to see 19)

    Selected Interacting proteins for FUT9 (ENSP000003025994) via UniProtKB, MINT, STRING, and/or I2D (see all 19)

    InteractantInteraction Details
    GeneCardExternal ID(s)
    B4GALT1ENSP000003690554STRING: ENSP00000369055
    B4GALT2ENSP000003492934STRING: ENSP00000349293
    B4GALT3ENSP000003209654STRING: ENSP00000320965
    FUT1ENSP000003120214STRING: ENSP00000312021
    FUT2ENSP000003757484STRING: ENSP00000375748
    About this table

    Gene Ontology (GO): 5 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005975carbohydrate metabolic process TAS10386598
    GO:0006486protein glycosylation TAS11698403
    GO:0007399nervous system development IEA--
    GO:0036065fucosylation TAS10386598
    GO:0042355L-fucose catabolic process NAS11698403

    FUT9 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for FUT9

    3 HMDB Compounds for FUT9    About this table
    CompoundSynonyms CAS #PubMed Ids
    GDP-L-fucoseGDP-beta-L-fucose (see all 5)15839-70-0--
    Guanosine diphosphate5'-GDP (see all 10)146-91-8--
    NeolactotetraoseLacto-N-neo-tetraose (see all 8)13007-32-4--

    1 Novoseek inferred chemical compound relationship for FUT9 gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    polylactosamine 79.7 3 10622713 (2)



    FUT9 for compounds           About GeneDecksing



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for FUT9 gene: 
    NM_006581.3  

    Unigene Cluster for FUT9:

    Fucosyltransferase 9 (alpha (1,3) fucosyltransferase)
    Hs.49117  [show with all ESTs]
    Unigene Representative Sequence: NM_006581
    2 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000483933 ENST00000302103(uc003pop.4)
    miRNA
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    Selected qRT-PCR Assays for microRNAs that regulate FUT9 (see all 136):
    hsa-miR-579 hsa-miR-361-5p hsa-miR-199a-3p hsa-miR-128 hsa-miR-3921 hsa-miR-4275 hsa-miR-130b hsa-miR-34c-5p
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    Additional mRNA sequence: 

    AB023021.1 AJ238701.1 AK095046.1 AK293817.1 AK314966.1 AL080093.1 AL833558.1 AY800264.1 
    BC001879.1 BC036101.1 

    5 DOTS entries:

    DT.111238  DT.92034930  DT.91891351  DT.121407215  DT.97772074 

    13 AceView cDNA sequences:

    CK904220 BC036101 BX345486 BC001879 BM021081 BM021317 AJ238701 NM_006581 
    CK904219 AB023021 BE266935 BX345483 BX345484 

    GeneLoc Exon Structure

    2 Alternative Splicing Database (ASD) splice patterns (SP) for FUT9    About this scheme

    ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5
    SP1:        -     -               
    SP2:                              


    ECgene alternative splicing isoforms for FUT9

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    FUT9 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GATGTCTTTC
    FUT9 Expression
    About this image


    FUT9 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 5) fully expand
     
     Brain (Nervous System)
             Amygdala
     
     Neurons
             nGnG Amacrine Cells Inner Nuclear Layer
     
     Eye (Sensory Organs)
             nGnG Amacrine Cells Inner Nuclear Layer
     
     Testis (Reproductive System)
     
     Kidney (Urinary System)
    FUT9 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    FUT9 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.49117

    UniProtKB/Swiss-Prot: FUT9_HUMAN, Q9Y231
    Tissue specificity: Strongly expressed in forebrain and stomach, lower expression in spleen and peripheral blood
    leukocytes, and no expression in small intestine, colon, liver, lung, kidney, adrenal cortex or uterus

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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FUT9

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for FUT9 gene from Selected species (see all 15)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Fut91 , 5 fucosyltransferase 91, 5 91.46(n)1
    99.44(a)1
      4 (10.59 cM)5
    143481  NM_010243.31  NP_034373.11 
     256093325 
    chicken
    (Gallus gallus)
    Aves FUT91 fucosyltransferase 9 (alpha (1,3) fucosyltransferase) 83.01(n)
    87.99(a)
      771133  NM_001079502.1  NP_001072970.1 
    lizard
    (Anolis carolinensis)
    Reptilia FUT96
    fucosyltransferase 9 (alpha (1,3) fucosyltransfera...
    86(a)
    1 ↔ 1
    GL343294.1(169086-170162)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia fut91 fucosyltransferase 9 (alpha (1,3) fucosyltransferase) 75.77(n)
    82.45(a)
      548391  NM_001015689.1  NP_001015689.1 
    zebrafish
    (Danio rerio)
    Actinopterygii BI326811.12   -- 73.58(n)   321072  BI326811.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta FucTA6
    FucTA
    21(a)
    1 ↔ 1
    3L(15140237-15147495)
    worm
    (Caenorhabditis elegans)
    Secernentea fut-46
    fut-56
    (see all 5)
    Protein FUT-5 (fut-5) mRNA, complete cds
    (see all 5)
    23(a)
    23(a)
    (see all 5)
    1 ↔ many
    1 ↔ many
    (see all 5)
    II(2819435-2822490) WBGene00001507
    II(4665893-4667588) WBGene00043986


    ENSEMBL Gene Tree for FUT9 (if available)
    TreeFam Gene Tree for FUT9 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for FUT9 gene
    FUT52  FUT42  FUT72  FUT32  FUT62  FUT112  FUT102  
    5 SIMAP similar genes for FUT9 using alignment to 3 protein entries:     FUT9_HUMAN (see all proteins):
    FUT5    FUT6    FUT3    FUT7    FUT4

    FUT9 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for FUT9 (see all 4118)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 6 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs715437411,2
    C--93969609(+) GTGTG-/TG/TGT
    GTGTGTGTG
    CGTGC
    1 -- int11NA 2
    rs1177429541,2
    F--96461878(+) ATTAAT/CTCTTG 1 -- us2k11Minor allele frequency- C:0.01NA 120
    rs69160751,2
    C--96461902(+) GCCCAA/TGTAGC 1 -- us2k14Minor allele frequency- T:0.27WA CSA EA 241
    rs1380057861,2
    --96461909(+) TAGCCA/GCTGGC 1 -- us2k10--------
    rs1158053451,2
    C,F--96462029(+) GAAAGA/CATAAC 1 -- us2k11Minor allele frequency- C:0.04WA 118
    rs65709911,2
    C,F,A,H--96462127(+) TATTTT/GTTCCC 1 -- us2k1 trp315Minor allele frequency- G:0.19NS EA WA CSA 2041
    rs15468981,2
    C,F,H--96462168(-) TTTACC/TTAATG 1 -- us2k126Minor allele frequency- T:0.09NS EA NA WA 2762
    rs786934141,2
    C--96462175(+) TAAATG/TTTGAA 1 -- us2k10--------
    rs93736181,2
    C,F--96462205(+) GATATA/TCTCAA 1 -- us2k12Minor allele frequency- T:0.08WA EA 238
    rs1908873591,2
    --96462237(+) GATACC/TGCCCA 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for FUT9 (96463845 - 96663488 bp)

    Structural Variations
         Database of Genomic Variants (DGV) Selected variations for FUT9 (see all 19):    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2669302CNV Deletion23128226
    esv2732455CNV Deletion23290073
    esv2675747CNV Deletion23128226
    esv2732458CNV Deletion23290073
    esv2732457CNV Deletion23290073
    esv2732456CNV Deletion23290073
    esv2422431CNV Duplication17116639
    esv1667871CNV Insertion17803354
    esv1046648CNV Insertion17803354
    esv271471CNV Insertion20981092

    Site Specific Mutation Identification with PCR Assays
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

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    OMIM gene information: 606865    OMIM disorders: --

    5 diseases for FUT9:    
    About MalaCards
    malaria    cytomegalovirus infection    pulmonary function    endotheliitis
    neuronitis


    FUT9 for disorders           About GeneDecksing

    Genetic Association Database (GAD): FUT9
    Human Genome Epidemiology (HuGE) Navigator: FUT9 (2 documents)

    Export disorders for FUT9 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for FUT9 gene, integrated from 10 sources (see all 34):
    (articles sorted by number of sources associating them with FUT9)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Alpha-1,3-fucosyltransferase IX (Fuc-TIX) is very highly conserved between human and mouse; molecular cloning, characterization and tissue distribution of human Fuc-TIX. (PubMed id 10386598)1, 2, 3, 9 Kaneko M.... Narimatsu H. (FEBS Lett. 1999)
    2. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (Mol. Med. 2010)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    4. The DNA sequence and analysis of human chromosome 6. (PubMed id 14574404)1, 2 Mungall A.J.... Beck S. (Nature 2003)
    5. FUT4 and FUT9 genes are expressed early in human embryogenesis. (PubMed id 10929005)1, 2 Cailleau-Thomas A.... Mennesson B. (Glycobiology 2000)
    6. Assignment of the human alpha 1,3-fucosyltransferase IX gene (FUT9) to chromosome band 6q16 by in situ hybridization. (PubMed id 10575236)1, 3 Kaneko M....Narimatsu H. (Cytogenet. Cell Genet. 1999)
    7. CD15 expression in mature granulocytes is determined by alpha 1,3-fucosyltransferase IX, but in promyelocytes and monocytes by alpha 1,3-fucosyltransferase IV. (PubMed id 11278338)1, 9 Nakayama F....Narimatsu H. (J. Biol. Chem. 2001)
    8. [Regulation by ovarian hormones of alpha 1,3-fucosyltransferase gene (FUT9) expression in human endometrium]. (PubMed id 12417923)1, 9 Li H....Yan B. (Sheng Wu Hua Xue Yu Sheng Wu Wu Li Xue Bao 2002)
    9. Alpha1,3-fucosyltransferase 9 (FUT9; Fuc-TIX) preferentially fucosylates the distal GlcNAc residue of polylactosamine chain while the other four alpha1,3FUT members preferentially fucosylate the inner GlcNAc residue. (PubMed id 10622713)1, 9 Nishihara S....Narimatsu H. (FEBS Lett. 1999)
    10. Human fucosyltransferase IX: specificity towards N-linked glycoproteins and relevance of the cytoplasmic domain in intra-Golgi localization. (PubMed id 18395013)1, 9 Brito C....Costa J. (Biochimie 2008)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section

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    Entrez Gene: 10690 HGNC: 4020 AceView: FUT9 Ensembl:ENSG00000172461 euGenes: HUgn10690
    ECgene: FUT9 Kegg: 10690 H-InvDB: FUT9

    (According to HUGE)
    About This Section

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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

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    NameDescription
    PharmGKB entry for FUT9 Pharmacogenomics, SNPs, Pathways
    GGDBhttp://jcggdb.jp/rcmg/ggdb/Homolog?cat=symbol&symbol=FUT9
    Functional Glycomics Gateway - GTasehttp://www.functionalglycomics.org/glycomics/molecule/jsp/glycoEnzyme/viewGlycoEnzyme.jsp?gbpId=gt_hum_606

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

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    Patent Information for FUT9 gene:
    Search GeneIP for patents involving FUT9

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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