Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 
or upload a file of gene symbols


Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

FUT5 Gene

protein-coding   GIFtS: 60
GCID: GC19M005865

Fucosyltransferase 5 (Alpha (1,3) Fucosyltransferase)

Microbiology & Infectious Diseases Congress
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Fucosyltransferase 5 (Alpha (1,3) Fucosyltransferase)1 2     Alpha-(1,3)-Fucosyltransferase 52
Fucosyltransferase V2 3     fucT-V2
Galactoside 3-L-Fucosyltransferase2 3     Fuc-TV3
EC 2.4.1.653 8     FucT-V3
FUC-TV2     Fucosyltransferase 53
Alpha (1,3) Fucosyltransferase2     EC 2.4.18

External Ids:    HGNC: 40161   Entrez Gene: 25272   Ensembl: ENSG000001303837   OMIM: 1368355   UniProtKB: Q111283   

Export aliases for FUT5 gene to outside databases

Previous GC identifers: GC19M005957 GC19M005805 GC19M005816 GC19M005625


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for FUT5 Gene: 
FUT5 (fucosyltransferase 5 (alpha (1,3) fucosyltransferase)) is a protein-coding gene. Diseases associated with FUT5 include cytomegalovirus infection, and herpes simplex, and among its related super-pathways are Metabolism. GO annotations related to this gene include 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity and fucosyltransferase activity. An important paralog of this gene is FUT4.

UniProtKB/Swiss-Prot: FUT5_HUMAN, Q11128
Function: May catalyze alpha-1,3 glycosidic linkages involved in the expression of VIM-2, Lewis X/SSEA-1 and
sialyl Lewis X antigens

Gene Wiki entry for FUT5 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000019.9  NC_018930.2  NT_011255.14  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the FUT5 gene promoter:
         c-Fos   E2F   AP-1   NRSF form 1   ATF-2   c-Jun   NRSF form 2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidFUT5 promoter sequence
   Search SABiosciences Chromatin IP Primers for FUT5

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat FUT5


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 19p13.3   Ensembl cytogenetic band:  19p13.3   HGNC cytogenetic band: 19p13.3

FUT5 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
FUT5 gene location

GeneLoc information about chromosome 19         GeneLoc Exon Structure

GeneLoc location for GC19M005865:  view genomic region     (about GC identifiers)

Start:
5,865,837 bp from pter      End:
5,903,798 bp from pter
Size:
37,962 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: FUT5_HUMAN, Q11128 (See protein sequence)
Recommended Name: Alpha-(1,3)-fucosyltransferase  
Size: 374 amino acids; 43008 Da
Subcellular location: Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein.
Note=Membrane-bound form in trans cisternae of Golgi
Secondary accessions: A8K4X2

Explore the universe of human proteins at neXtProt for FUT5: NX_Q11128

Explore proteomics data for FUT5 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q11128

  • 4/20 DME Specific Peptides for FUT5 (Q11128) (see all 20)
     VPVVLGP  CFFSYLR  FIHVDDF  ADCNITA 

    FUT5 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    FUT5 Protein Expression
    REFSEQ proteins: NP_002025.2  
    ENSEMBL proteins: 
     ENSP00000466880   ENSP00000252675  

    Human Recombinant Protein Products for FUT5: 
    Browse Purified and Recombinant Proteins at EMD Millipore
    R&D Systems Recombinant & Natural Proteins for FUT5 (Fucosyltransferase 5/FUT5)
    Browse recombinant and purified proteins available from Enzo Life Sciences
    Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
    OriGene Protein Over-expression Lysate for FUT5
    OriGene Custom MassSpec 
    OriGene Custom Protein Services for FUT5
    GenScript Custom Purified and Recombinant Proteins Services for FUT5
    Novus Biologicals FUT5 Protein
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for FUT5 

    Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005794Golgi apparatus TAS11698403
    GO:0016020membrane ----
    GO:0016021integral to membrane IEA--
    GO:0032580Golgi cisterna membrane IEA--

    FUT5 for ontologies           About GeneDecksing



    FUT5 Antibody Products: 
    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    R&D Systems Antibodies for FUT5 (Fucosyltransferase 5/FUT5)
    Browse OriGene Antibodies
    OriGene Custom Antibody Services for FUT5
    GenScript Custom Superior Antibodies Services for FUT5
    Novus Biologicals FUT5 Antibodies
    Abcam antibodies for FUT5
    Cloud-Clone Corp. Antibodies for FUT5 
    ThermoFisher Antibody for FUT5
    LSBio Antibodies in human, mouse, rat for FUT5 

    Assay Products for FUT5: 
    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for FUT5
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for FUT5
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for FUT5 
    Cloud-Clone Corp. CLIAs for FUT5


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    FUT: Fucosyltransferases

    1 InterPro protein domain:
     IPR001503 Glyco_trans_10

    Graphical View of Domain Structure for InterPro Entry Q11128

    ProtoNet protein and cluster: Q11128

    1 Blocks protein domain: IPB001503 Glycosyl transferase

    UniProtKB/Swiss-Prot: FUT5_HUMAN, Q11128
    Similarity: Belongs to the glycosyltransferase 10 family


    FUT5 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: FUT5_HUMAN, Q11128
    Function: May catalyze alpha-1,3 glycosidic linkages involved in the expression of VIM-2, Lewis X/SSEA-1 and
    sialyl Lewis X antigens
    Catalytic activity: GDP-beta-L-fucose + beta-D-galactosyl-(1->3)-N-acetyl-D-glucosaminyl-R = GDP +
    beta-D-galactosyl-(1->3)-(alpha-L-fucosyl-(1->4))-N-acetyl-beta-D-glucosaminyl-R

         Genatlas biochemistry entry for FUT5:
    fucosyltransferase,alpha-(1,3),5 (FucT-V),plasma

         Enzyme Numbers (IUBMB): EC 2.4.1.651 2 EC 2.4.12

         Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0008417fucosyltransferase activity TAS1339443
    GO:00170603-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity IEA--
    GO:0046920alpha-(1->3)-fucosyltransferase activity TAS11698403
         
    FUT5 for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for FUT5:
     Increased circadian period len 

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for FUT5 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for FUT5

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for FUT5 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for FUT5 

    miRNA
    Products:
        
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat FUT5
    Search QIAGEN for miScript miRNA Assays for microRNAs that regulate FUT5
    SwitchGear 3'UTR luciferase reporter plasmidFUT5 3' UTR sequence
    Inhib. RNA
    Products:
        
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for FUT5
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat FUT5

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for FUT5
    Sirion Biotech Customized adenovirus for overexpression of FUT5

    Clone
    Products:
         
    Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
    OriGene clones in human, mouse for FUT5 (see all 5)
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: FUT5 (NM_002034)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for FUT5
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FUT5
    Sirion Biotech Customized lentivirus for stable overexpression of FUT5 
                         Customized lentivirus expression plasmids for stable overexpression of FUT5 

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for FUT5
    Search LifeMap BioReagents cell lines for FUT5
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FUT5


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for FUT5 About                                                                                                See pathways by source

    SuperPathContained pathways About
    1Metabolism
    Metabolic pathways0.40
    2Glycosphingolipid biosynthesis - lacto and neolacto series
    Glycosphingolipid biosynthesis - lacto and neolacto series

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways



    2         Kegg Pathways  (Kegg details for FUT5):
        Glycosphingolipid biosynthesis - lacto and neolacto series
    Metabolic pathways

    UniProtKB/Swiss-Prot: FUT5_HUMAN, Q11128
    Pathway: Protein modification; protein glycosylation


    FUT5 for pathways           About GeneDecksing

    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for FUT5

    STRING Interaction Network Preview (showing 5 interactants - click image to see 16)

    5/16 Interacting proteins for FUT5 (ENSP000002526754) via UniProtKB, MINT, STRING, and/or I2D (see all 16)

    InteractantInteraction Details
    GeneCardExternal ID(s)
    B3GNT3ENSP000003218744STRING: ENSP00000321874
    B4GALT1ENSP000003690554STRING: ENSP00000369055
    B4GALT2ENSP000003492934STRING: ENSP00000349293
    FUT1ENSP000003120214STRING: ENSP00000312021
    FUT2ENSP000003757484STRING: ENSP00000375748
    About this table

    Gene Ontology (GO): 4 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005975carbohydrate metabolic process TAS1339443
    GO:0006486protein glycosylation TAS11698403
    GO:0036065fucosylation TAS1339443
    GO:0042355L-fucose catabolic process NAS11698403

    FUT5 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section

    FUT5 for compounds           About GeneDecksing

    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for FUT5

    2 HMDB Compounds for FUT5    About this table
    CompoundSynonyms CAS #PubMed Ids
    GDP-L-fucoseGDP-beta-L-fucose (see all 5)15839-70-0--
    Guanosine diphosphate5'-GDP (see all 10)146-91-8--

    2 Novoseek inferred chemical compound relationships for FUT5 gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    gdp fucose 81.5 1 7721776 (1)
    gdp 46.7 1 8780523 (1)

    Search CenterWatch for drugs/clinical trials and news about FUT5

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for FUT5 gene: 
    NM_002034.2  

    Unigene Cluster for FUT5:

    Fucosyltransferase 5 (alpha (1,3) fucosyltransferase)
    Hs.631843  [show with all ESTs]
    Unigene Representative Sequence: NM_002034
    2 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000588525 ENST00000252675(uc002mdo.4 uc010duo.3)
    Congresses - knowledge worth sharing:  
    European Congress of Clinical Microbiology and Infectious Diseases (ECCMID) 10 - 13 May 2014

    miRNA
    Products:
         
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat FUT5
    Search QIAGEN for miScript miRNA Assays for microRNAs that regulate FUT5
    SwitchGear 3'UTR luciferase reporter plasmidFUT5 3' UTR sequence
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for FUT5
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat FUT5
    Clone
    Products:
         
    OriGene clones in human, mouse for FUT5 (see all 5)
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: FUT5 (NM_002034)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for FUT5
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FUT5
    Sirion Biotech Customized lentivirus for stable overexpression of FUT5 
                         Customized lentivirus expression plasmids for stable overexpression of FUT5 
    Primer
    Products:
        
    OriGene qSTAR qPCR primer pairs in human, mouse for FUT5
    SABiosciences RT2 qPCR Primer Assay in human, mouse / rat FUT5
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat FUT5
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat FUT5

    Additional mRNA sequence: 

    BC140905.1 U27329.1 U27330.1 

    1 DOTS entry:

    DT.105397 

    3 AceView cDNA sequences:

    NM_002034 U27329 U27330 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    FUT5 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: AGGGGTGCAA
    FUT5 Expression
    About this image


    See FUT5 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for FUT5

    SOURCE GeneReport for Unigene cluster: Hs.631843

    UniProtKB/Swiss-Prot: FUT5_HUMAN, Q11128
    Tissue specificity: Liver, colon and testis and trace amounts in T-cells and brain

        SABiosciences Custom PCR Arrays for FUT5
    Primer
    Products:
    OriGene qSTAR qPCR primer pairs in human, mouse for FUT5
    SABiosciences RT2 qPCR Primer Assay in human, mouse / rat FUT5
    QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat FUT5
    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat FUT5
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FUT5

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for FUT5 gene from 6/11 species (see all 11)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    dog
    (Canis familiaris)
    Mammalia FUT51 fucosyltransferase 5 (alpha (1,3) fucosyltransferase) 77.91(n)
    69.5(a)
      449024  NM_001005378.1  NP_001005378.1 
    chicken
    (Gallus gallus)
    Aves FUT51 fucosyltransferase 5 (alpha (1,3) fucosyltransferase) 60.19(n)
    51.59(a)
      428341  XM_425901.1  XP_425901.1 
    lizard
    (Anolis carolinensis)
    Reptilia --
    Uncharacterized protein
    49(a)
    1 → many
    AAWZ02038436(4451-5581)
    zebrafish
    (Danio rerio)
    Actinopterygii fut96
    --
    (see all 15)
    --
    36(a)
    35(a)
    (see all 15)
    many ↔ many
    many ↔ many
    (see all 15)
    8(3512976-3517595)
    8(3626455-3650896)
    fruit fly
    (Drosophila melanogaster)
    Insecta FucTA1 , 3 protein amino acid glycosylation
    galactoside 3-L-fucosyltransferase3
    CG6869-PA1
    35(a)
    (best of 2)3
    53.75(n)1
    39.53(a)1
      71B63
    396531  NM_140497.21  NP_648754.21 
    worm
    (Caenorhabditis elegans)
    Secernentea fut-31 Protein FUT-3 41.9(n)
    32.99(a)
      173958  NM_062705.6  NP_495106.1 


    ENSEMBL Gene Tree for FUT5 (if available)
    TreeFam Gene Tree for FUT5 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for FUT5 gene
    FUT42  FUT72  FUT32  FUT62  FUT112  FUT102  FUT92  
    5 SIMAP similar genes for FUT5 using alignment to 2 protein entries:     FUT5_HUMAN (see all proteins):
    FUT3    FUT6    FUT9    FUT7    FUT4

    FUT5 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/273 SNPs in FUT5 are shown (see all 273)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 19 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1143308421,2
    F--5865445(+) GACCTG/AAGACC 1 -- ds50011Minor allele frequency- A:0.03WA 118
    rs779338181,2
    C--5865470(+) TTTCAC/ATTCTG 1 -- ds50012Minor allele frequency- A:0.07WA 120
    rs1499365451,2
    --5865540(+) GAACGA/CCTCCC 1 -- ds50010--------
    rs1926154791,2
    --5865604(+) CCCTGA/GACATT 1 -- ds50010--------
    rs1449891011,2
    --5865624(+) CATTGC/TTGGTT 1 -- ds50010--------
    rs104267091,2
    C,F,H--5865645(+) CGACTC/TGTGCA 1 -- ds500121Minor allele frequency- T:0.08NS EA NA CSA WA 2642
    rs735386521,2
    C,F--5865672(+) GTAACC/ACTGGC 1 -- ds50012Minor allele frequency- A:0.13WA 120
    rs1844886271,2
    --5865804(+) AGGGGA/GGACAC 1 -- ds50010--------
    rs118814701,2
    C,F,H--5865837(+) TCGCCT/CGAAAA 1 -- ut3120Minor allele frequency- C:0.04NS EA NA WA 2036
    rs1490685441,2
    C--5865907(+) CAAGCA/CAACCA 1 -- ut310--------

    HapMap Linkage Disequilibrium report for FUT5 (5865837 - 5903798 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 4 variations for FUT5:    About this table     
    Variant IDTypeSubtypePubMed ID
    nsv910905CNV Loss21882294
    nsv910904CNV Loss21882294
    dgv3693n71CNV Loss21882294
    nsv482210CNV Gain20164927

    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing FUT5
    DNA2.0 Custom Variant and Variant Library Synthesis for FUT5

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 136835    OMIM disorders: --

    7 diseases for FUT5:    About MalaCards
    cytomegalovirus infection    herpes simplex    gastric cancer    colorectal cancer
    prostate cancer    prostatitis    breast cancer


    FUT5 for disorders           About GeneDecksing

    Human Genome Epidemiology (HuGE) Navigator: FUT5 (1 document)

    Export disorders for FUT5 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for FUT5 gene, integrated from 9 sources (see all 45):
    (articles sorted by number of sources associating them with FUT5)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Isolation of a novel human alpha (1,3)fucosyltransferase gene and molecular comparison to the human Lewis blood group alpha (1,3/1,4)fucosyltransferase gene. Syntenic, homologous, nonallelic genes encoding enzymes with distinct acceptor substrate specificities. (PubMed id 1740457)1, 2, 3 Weston B.W....Lowe J.B. (1992)
    2. Expression of human chromosome 19p alpha(1,3)-fucosyltransferase genes in normal tissues. Alternative splicing, polyadenylation, and isoforms. (PubMed id 7650030)1, 2, 9 Cameron H.S.... Weston B.W. (1995)
    3. Glycodelin-A interacts with fucosyltransferase on human sperm plasma membrane to inhibit spermatozoa-zona pellucida binding. (PubMed id 17148576)1, 9 Chiu P.C....Yeung W.S. (2007)
    4. Alpha1,3-fucosyltransferase 9 (FUT9; Fuc-TIX) preferentially fucosylates the distal GlcNAc residue of polylactosamine chain while the other four alpha1,3FUT members preferentially fucosylate the inner GlcNAc residue. (PubMed id 10622713)1, 9 Nishihara S....Narimatsu H. (1999)
    5. Physical maps of human alpha (1,3)fucosyltransferase genes FUT3-FUT6 on chromosomes 19p13.3 and 11q21. (PubMed id 7782074)1, 9 McCurley R.S....Weston B.W. (1995)
    6. [Distribution specificity of human fucosyltransferase 5 and its expression and localization in spermatids]. (PubMed id 22619806)1 Li F.R....Pang H. (2012)
    7. Down-regulation of FUT3 and FUT5 by shRNA alters Lewi s antigens expression and reduces the adhesion capacities of gastric cancer cel ls. (PubMed id 21978830)1 PadrA^ M....de BolA^s C. (2011)
    8. [The genetic diversity in the full coding region of h uman FUT5 gene in a Chinese Han population]. (PubMed id 20677162)1 Li F.R....Pang H. (2010)
    9. Activation of host antiviral RNA-sensing factors nece ssary for herpes simplex virus type 1-activated transcription of host cell fuco syltransferase genes FUT3, FUT5, and FUT6 and subsequent expression of sLe(x) i n virus-infected cells. (PubMed id 19349624)1 NordAcn R....Olofsson S. (2009)
    10. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)2 Ota T.... Sugano S. (2004)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 2527 HGNC: 4016 AceView: FUT5 Ensembl:ENSG00000130383 euGenes: HUgn2527
    ECgene: FUT5 Kegg: 2527 H-InvDB: FUT5

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for FUT5 Pharmacogenomics, SNPs, Pathways
    GGDBhttp://riodb.ibase.aist.go.jp/rcmg/ggdb/Homolog?cat=symbol&symbol=FUT5
    Functional Glycomics Gateway - GTasehttp://www.functionalglycomics.org/glycomics/molecule/jsp/glycoEnzyme/viewGlycoEnzyme.jsp?gbpId=gt_hum_602

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for FUT5 gene:
    Search GeneIP for patents involving FUT5

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

     
     EMD Millipore Custom Antibody & Bulk Services
     EMD Millipore Preclinical / Clinical Development Services
     EMD Millipore Immunoassay Services
     EMD Millipore Target Screening & Profiling Services

      
     Antibodies for FUT5 (Fucosyltransferase 5/FUT5)   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Kinase Activity Assays/Reagents  
     Browse ELISpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Multiplex/Array Assay Kits/Reagents  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Protease Activity Assays and Reagents   Recombinant/Natural Proteins for FUT5 (Fucosyltransferase 5/FUT5)  
     Browse Stem Cell Products   Browse Tocris Biochemicals & Compounds  
     Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
     Browse OriGene Antibodies   OriGene RNAi products in human, mouse, rat for FUT5  
     Browse OriGene qPCR primer pairs and template standards   OriGene Protein Over-expression Lysate for FUT5  
     OriGene Custom Mass Spec   OriGene clones in human, mouse for FUT5  
     OriGene qSTAR qPCR primer pairs in human, mouse for FUT5   Browse OriGene full length recombinant human proteins expressed in human HEK293 cells  
     Browse OriGene ORF clones   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for FUT5   OriGene Custom Protein Services for FUT5  

     
     
     QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat FUT5
     QIAGEN SeqTarget long-range PCR primers for resequencing FUT5
     QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat FUT5
     QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat FUT5
     QIAGEN QuantiFast Probe-based Assays in human, mouse, rat FUT5
     QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat FUT5
     GenScript Custom Purified and Recombinant Proteins Services for FUT5 GenScript cDNA clones with any tag delivered in your preferred vector for FUT5
     GenScript Custom Assay Services for FUT5 GenScript Custom Superior Antibodies Services for FUT5
     GenScript Custom overexpressing Cell Line Services for FUT5 CloneReady with Over 120,000 Genes
     Gene Synthesis: Any Gene in Any Vector Vector-based siRNA and miRNA, Ready for Transfection
     Gene Mutant Library, Variants up to 10^11 Plasmid Preparation
     Custom Peptide Services
     Search for Antibodies & Assays

     Regulatory tfbs in FUT5 promoter
     Search Chromatin IP Primers for FUT5
     RT2 qPCR Primer Assay in human, mouse / rat FUT5
     GNC Network for FUT5
     SABiosciences Custom PCR Arrays for FUT5
     Search Tocris compounds for FUT5
     Browse Sino Biological Proteins and Antibodies
     Browse Sino Biological Cell Lysates
     Browse Sino Biological cDNA Clones
     4000+ Proteins
     Search Sino Biological for antibodies, proteins & pathways
     Protein Production Services
     Transfection Reagents
     Protein A/G/L resins
     Isotyping reagents
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies
     Novus Tissue Slides
     FUT5 antibodies
     FUT5 proteins
     Antibodies for FUT5
     See all of Abcam's Antibodies, Kits and Proteins for FUT5
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins




     Proteins for FUT5
     Antibodies for FUT5
     ELISAs for FUT5
     CLIAs for FUT5
     Search LifeMap BioReagents cell lines for FUT5
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FUT5
     SwitchGear 3'UTR luciferase reporter plasmids for FUT5
     SwitchGear Promoter luciferase reporter plasmids for FUT5
     ThermoFisher Antibody for FUT5
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FUT5
     inGenious Targeting Laboratory - Custom generated mouse model solutions for FUT5
     inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for FUT5
    Customized:
     lentivirus for stable overexpression of FUT5
     lentivirus expression plasmids for stable overexpression of FUT5
     adenovirus for overexpression of FUT5
     LSBio Antibodies in human, mouse, rat for FUT5
    Customized transgenic rodents for:
     Humanization
     Biomarker expression
     Off-target effect monitoring
     Translational medicine
     Tissue-specific gene expresssion
     Time-controlled gene expresssion
           
    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 3 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

    View Random Gene

    Category
    (GIFtS: 73)
    transforming growth factor, beta 1
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      FUT5 gene at Home site.
    hostname: 356980-web2.xennexinc.com index build: 106 solr: 1.4