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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

FUT1 Gene

protein-coding   GIFtS: 59
GCID: GC19M049251

Fucosyltransferase 1 (Galactoside 2-Alpha-L-Fucosyltransferase,...

(Previous names: fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase,...)
(Previous symbols: H, HSC)
Microbiology & Infectious Diseases Congress
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Fucosyltransferase 1 (Galactoside 2-Alpha-L-Fucosyltransferase, H Blood
Group)1 2
     EC 2.4.1.693 8
H1 2 3 5     HH2 5
HSC1 2 3     Fucosyltransferase 1 (Galactoside 2-Alpha-L-Fucosyltransferase, Bombay
Phenotype Included)1
Fucosyltransferase 1 (Galactoside 2-Alpha-L-Fucosyltransferase)1 2     2-alpha-L-fucosyltransferase2
Alpha(1,2)FT 12 3     Alpha (1,2) Fucosyltransferase2
Blood Group H Alpha 2-Fucosyltransferase2 3     Galactoside 2-Alpha-L-Fucosyltransferase 12
GDP-L-Fucose:Beta-D-Galactoside 2-Alpha-L-Fucosyltransferase 12 3     Fucosyltransferase 13

External Ids:    HGNC: 40121   Entrez Gene: 25232   Ensembl: ENSG000001749517   OMIM: 2111005   UniProtKB: P195263   

Export aliases for FUT1 gene to outside databases

Previous GC identifers: GC19M049964 GC19M049619 GC19M053927 GC19M053943 GC19M045630


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for FUT1 Gene:
The protein encoded by this gene is a Golgi stack membrane protein that is involved in the creation of a precursor
of the H antigen, which is required for the final step in the soluble A and B antigen synthesis pathway. This
gene is one of two encoding the galactoside 2-L-fucosyltransferase enzyme. Mutations in this gene are a cause of
the H-Bombay blood group. (provided by RefSeq, Jul 2008)

GeneCards Summary for FUT1 Gene: 
FUT1 (fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group)) is a protein-coding gene. Diseases associated with FUT1 include hemorrhagic disease, and cytomegalovirus infection, and among its related super-pathways are Glycosphingolipid biosynthesis - ganglio series and Metabolism. GO annotations related to this gene include galactoside 2-alpha-L-fucosyltransferase activity and fucosyltransferase activity. An important paralog of this gene is FUT2.

UniProtKB/Swiss-Prot: FUT1_HUMAN, P19526
Function: Creates a soluble precursor oligosaccharide FuC-alpha ((1,2)Galbeta-) called the H antigen which is an
essential substrate for the final step in the soluble A and B antigen synthesis pathway. H and Se enzymes
fucosylate the same acceptor substrates but exhibit different Km values

Gene Wiki entry for FUT1 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000019.9  NT_011109.16  NC_018930.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the FUT1 gene promoter:
         PPAR-gamma1   p300   MyoD   STAT3   PPAR-gamma2   ATF   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidFUT1 promoter sequence
   Search SABiosciences Chromatin IP Primers for FUT1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat FUT1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 19q13.3   Ensembl cytogenetic band:  19q13.33   HGNC cytogenetic band: 19q13.33

FUT1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
FUT1 gene location

GeneLoc information about chromosome 19         GeneLoc Exon Structure

GeneLoc location for GC19M049251:  view genomic region     (about GC identifiers)

Start:
49,251,268 bp from pter      End:
49,258,647 bp from pter
Size:
7,380 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: FUT1_HUMAN, P19526 (See protein sequence)
Recommended Name: Galactoside 2-alpha-L-fucosyltransferase 1  
Size: 365 amino acids; 41251 Da
Subcellular location: Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein.
Note=Membrane-bound form in trans cisternae of Golgi
Miscellaneous: There are two genes (FUT1 and FUT2) which encode galactoside 2-L-fucosyltransferase. They are
expressed in a tissue-specific manner with expression restricted to cells of mesodermal or endodermal origin
respectively
Secondary accessions: O14505 O14506 O14507

Explore the universe of human proteins at neXtProt for FUT1: NX_P19526

Explore proteomics data for FUT1 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_P19526

  • 4/19 DME Specific Peptides for FUT1 (P19526) (see all 19)
     LAPVFRI  EFTLHDH  AAFLPEW  PVFVVTS 

    FUT1 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    FUT1 Protein Expression
    REFSEQ proteins: NP_000139.1  
    ENSEMBL proteins: 
     ENSP00000312021  

    Human Recombinant Protein Products for FUT1: 
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    Cloud-Clone Corp. Proteins for FUT1 

    Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005794Golgi apparatus TAS11698403
    GO:0005887integral to plasma membrane TAS2118655
    GO:0016020membrane TAS2118655
    GO:0032580Golgi cisterna membrane IEA--

    FUT1 for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    FUT: Fucosyltransferases
    bloodgroup: Blood group antigens

    1 InterPro protein domain:
     IPR002516 Glyco_trans_11

    Graphical View of Domain Structure for InterPro Entry P19526

    ProtoNet protein and cluster: P19526

    1 Blocks protein domain: IPB002516 Glycosyl transferase

    UniProtKB/Swiss-Prot: FUT1_HUMAN, P19526
    Similarity: Belongs to the glycosyltransferase 11 family


    FUT1 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: FUT1_HUMAN, P19526
    Function: Creates a soluble precursor oligosaccharide FuC-alpha ((1,2)Galbeta-) called the H antigen which is an
    essential substrate for the final step in the soluble A and B antigen synthesis pathway. H and Se enzymes
    fucosylate the same acceptor substrates but exhibit different Km values
    Catalytic activity: GDP-beta-L-fucose +
    beta-D-galactosyl-(1->3)-N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide
    = GDP +
    alpha-L-fucosyl-(1->2)-beta-D-galactosyl-(1->3)-N-acetyl-beta-D-glucosaminyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide

         Genatlas biochemistry entry for FUT1:
    fucosyltransferase,alpha-(1,2),1 (synthesis of H blood antigen),regulating the expression of ABO antigenes in
    erythrocyte membranes and related antigens in several tissues

         Enzyme Number (IUBMB): EC 2.4.1.691 2

         Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0008107galactoside 2-alpha-L-fucosyltransferase activity TAS11698403
    GO:0008417fucosyltransferase activity TAS2118655
         
    FUT1 for ontologies           About GeneDecksing


    Phenotypes:
         2 MGI mutant phenotypes (inferred from 1 allele(MGI details for Fut1):
     endocrine/exocrine gland  reproductive system 

    FUT1 for phenotypes           About GeneDecksing

    Animal Models:
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    SwitchGear 3'UTR luciferase reporter plasmidFUT1 3' UTR sequence
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for FUT1 About                                                                                                See pathways by source

    SuperPathContained pathways About
    1Ganglio Sphingolipid Metabolism
    Ganglio Sphingolipid Metabolism0.53
    2Metabolism
    Metabolic pathways0.40
    3Glycosphingolipid biosynthesis - lacto and neolacto series
    Glycosphingolipid biosynthesis - lacto and neolacto series
    4Glycosphingolipid biosynthesis - globo series
    Glycosphingolipid biosynthesis - globo series

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    1 BioSystems Pathway for FUT1
        Ganglio Sphingolipid Metabolism


    3         Kegg Pathways  (Kegg details for FUT1):
        Glycosphingolipid biosynthesis - lacto and neolacto series
    Glycosphingolipid biosynthesis - globo series
    Metabolic pathways

    UniProtKB/Swiss-Prot: FUT1_HUMAN, P19526
    Pathway: Protein modification; protein glycosylation


    FUT1 for pathways           About GeneDecksing

    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for FUT1

    STRING Interaction Network Preview (showing 5 interactants - click image to see 24)

    5/24 Interacting proteins for FUT1 (ENSP000003120214) via UniProtKB, MINT, STRING, and/or I2D (see all 24)

    InteractantInteraction Details
    GeneCardExternal ID(s)
    B3GALT5ENSP000003433184STRING: ENSP00000343318
    B3GNT2ENSP000003055954STRING: ENSP00000305595
    B3GNT4ENSP000003196364STRING: ENSP00000319636
    B4GALT1ENSP000003690554STRING: ENSP00000369055
    FUT3ENSP000003056034STRING: ENSP00000305603
    About this table

    Gene Ontology (GO): 4 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005975carbohydrate metabolic process TAS2118655
    GO:0006486protein glycosylation TAS11698403
    GO:0036065fucosylation ----
    GO:0042355L-fucose catabolic process NAS11698403

    FUT1 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section

    FUT1 for compounds           About GeneDecksing

    Browse Small Molecules at EMD Millipore
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    Browse Tocris compounds for FUT1

    2 HMDB Compounds for FUT1    About this table
    CompoundSynonyms CAS #PubMed Ids
    GDP-L-fucoseGDP-beta-L-fucose (see all 5)15839-70-0--
    Guanosine diphosphate5'-GDP (see all 10)146-91-8--

    1 Novoseek inferred chemical compound relationship for FUT1 gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    galactose 36.1 1 11479278 (1)

    Search CenterWatch for drugs/clinical trials and news about FUT1

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for FUT1 gene: 
    NM_000148.3  

    Unigene Cluster for FUT1:

    Fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group)
    Hs.69747  [show with all ESTs]
    Unigene Representative Sequence: NM_000148
    5 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000310160(uc002pkk.3 uc002pkl.1 uc002pkm.1) ENST00000601931
    ENST00000599826 ENST00000597220 ENST00000601988
    Congresses - knowledge worth sharing:  
    European Congress of Clinical Microbiology and Infectious Diseases (ECCMID) 10 - 13 May 2014

    miRNA
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    8 QIAGEN miScript miRNA Assays for microRNAs that regulate FUT1:
    hsa-miR-1178 hsa-miR-125a-5p hsa-miR-125b hsa-miR-670 hsa-miR-767-3p hsa-miR-513a-5p hsa-miR-1291 hsa-miR-4319
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    Additional mRNA sequence: 

    BC074732.2 D87935.1 D87936.1 D87937.1 D87938.1 D87939.1 D87940.1 D87941.1 
    M35531.1 

    3 DOTS entries:

    DT.411909  DT.121451256  DT.100787200 

    24/41 AceView cDNA sequences (see all 41):

    BC074732 M35531 CA435895 NM_000148 AW664940 BF439550 AI910408 BM789542 
    BF196142 CK023853 R91944 BU631184 D87938 D87941 D87939 D87937 
    BM790913 BM851542 AA781233 D87936 BX489705 D87935 CA454198 AW241776 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    FUT1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CCTGTAGGCT
    FUT1 Expression
    About this image


    See FUT1 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for FUT1

    SOURCE GeneReport for Unigene cluster: Hs.69747
        SABiosciences Expression via Pathway-Focused PCR Array including FUT1: 
              Mesenchymal Stem Cell in human mouse rat

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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for FUT1 gene from 3/8 species (see all 8)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Fut11 , 5 fucosyltransferase 11, 5 77.25(n)1
    78.83(a)1
      7 (29.39 cM)5
    143431  NM_008051.51  NP_032077.21 
     456176065 
    lizard
    (Anolis carolinensis)
    Reptilia --
    Uncharacterized protein
    53(a)
    1 → many
    GL343329.1(853192-856474)
    worm
    (Caenorhabditis elegans)
    Secernentea B0205.46
    Protein B0205.4
    17(a)
    1 → many
    I(10741369-10744443)


    ENSEMBL Gene Tree for FUT1 (if available)
    TreeFam Gene Tree for FUT1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for FUT1 gene
    FUT22  
    4 SIMAP similar genes for FUT1 using alignment to 16 protein entries:     FUT1_HUMAN (see all proteins):
    h1    h2    sej    FUT2

    FUT1 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    UniProtKB/Swiss-Prot: FUT1_HUMAN, P19526
    Polymorphism: Nonfunctional mutant of FUT1 are the cause of the H-Bombay blood group


    10/331 SNPs in FUT1 are shown (see all 331)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 19 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1048946861,2
    Cpathogenic149430147(-) GCCTAC/GCTGGC 2 Y * stg10--------
    rs1048946881,2
    Cpathogenic149430269(-) CCTCCC/TAGGGC 2 Q * stg10--------
    rs289345881,2,4
    Cpathogenic149430370(-) CTACCG/TCCGGC 2 R L mis1 ese30--------
    rs1048946871,2
    Cpathogenic149430604(-) GAAGCA/TCTCTG 2 H L mis10--------
    VAR_0097084
    ----see VAR_0097082 L H mis40--------
    VAR_0034214
    ----see VAR_0034212 W C mis40--------
    VAR_0034174
    ----see VAR_0034172 Y C mis40--------
    VAR_0034184
    ----see VAR_0034182 W C mis40--------
    VAR_0034204
    ----see VAR_0034202 A V mis40--------
    VAR_0034194
    ----see VAR_0034192 V E mis40--------

    HapMap Linkage Disequilibrium report for FUT1 (49251268 - 49258647 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 6 variations for FUT1:    About this table     
    Variant IDTypeSubtypePubMed ID
    esv2718685CNV Deletion23290073
    nsv833855CNV Loss17160897
    dgv3967n71CNV Loss21882294
    dgv3968n71CNV Loss21882294
    nsv912244CNV Gain21882294
    nsv9739CNV Gain+Loss18304495


    Human Gene Mutation Database (HGMD): FUT1

    Locus Specific Mutation Databases (LSDB): FUT1
    Blood Group Antigen Gene Mutation Database (BGMUT) blood group system
    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing FUT1
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 211100    OMIM disorders: --

    17 diseases for FUT1:    About MalaCards
    hemorrhagic disease    cytomegalovirus infection    acne    epididymitis
    diarrhea    cholestasis    herpes simplex    colon cancer
    pancreatic cancer    pancreatitis    gastric cancer    ovarian cancer
    lung cancer    prostate cancer    melanoma    prostatitis
    endotheliitis


    FUT1 for disorders           About GeneDecksing

    5 Novoseek inferred disease relationships for FUT1 gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    colon cancer 24.4 4 17459061 (2), 12652076 (2)
    gastric cancer 0.611 1 9054453 (1)
    metastasis 0 1 17897065 (1)
    tumors 0 5 18205178 (2), 14742243 (1), 9054453 (1)
    cancer 0 3 14742243 (1), 9054453 (1)

    Genetic Association Database (GAD): FUT1
    Human Genome Epidemiology (HuGE) Navigator: FUT1 (3 documents)

    Export disorders for FUT1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for FUT1 gene, integrated from 9 sources (see all 90):
    (articles sorted by number of sources associating them with FUT1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Missense mutation of FUT1 and deletion of FUT2 are responsible for Indian Bombay phenotype of ABO blood group system. (PubMed id 9299444)1, 2, 9 Koda Y.... Kimura H. (1997)
    2. [Study on the frequency of alpha-1,2-fucosyltransferase gene h4 allele (C35T) in Chinese population] (PubMed id 16331565)1, 4, 9 Xu X.G....Yan L.X. (2005)
    3. Polymorphism of the h allele and the population frequency of sporadic nonfunctional alleles. (PubMed id 9122901)1, 2, 9 Wagner F.F. and Flegel W.A. (1997)
    4. Two prevalent h alleles in para-Bombay haplotypes among 250,000 Taiwanese. (PubMed id 15487706)1, 4 Chen D.P....Sun C.F. (2004)
    5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    6. Wide variety of point mutations in the H gene of Bombay and para- Bombay individuals which inactivate H enzyme. (PubMed id 9226185)1, 2 Kaneko M.... Narimatsu H. (1997)
    7. Molecular basis for H blood group deficiency in Bombay (Oh) and para- Bombay individuals. (PubMed id 7912436)1, 2 Kelly R.J....Lowe J.B. (1994)
    8. Molecular cloning, sequence, and expression of a human GDP-L- fucose:beta-D-galactoside 2-alpha-L-fucosyltransferase cDNA that can form the H blood group antigen. (PubMed id 2118655)1, 2 Larsen R.D.... Lowe J.B. (1990)
    9. Structure and expression of H-type GDP-L-fucose:beta-D-galactoside 2-alpha-L-fucosyltransferase gene (FUT1). Two transcription start sites and alternative splicing generate several forms of FUT1 mRNA. (PubMed id 9054453)1, 9 Koda Y....Kimura H. (1997)
    10. [Molecular genetic analysis of FUT1 and FUT2 gene in para-Bombay Chinese: a novel FUT1 allele is identified] (PubMed id 17922418)1, 9 Su Y....Li D.C. (2007)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Disorders
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    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 2523 HGNC: 4012 AceView: FUT1 Ensembl:ENSG00000174951 euGenes: HUgn2523
    ECgene: FUT1 Kegg: 2523 H-InvDB: FUT1

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for FUT1 Pharmacogenomics, SNPs, Pathways
    dbRBC/BGMUThttp://www.ncbi.nlm.nih.gov/gv/mhc/xslcgi.cgi?cmd=bgmut/systems_info&system=hh
    GGDBhttp://riodb.ibase.aist.go.jp/rcmg/ggdb/Homolog?cat=symbol&symbol=FUT1
    SeattleSNPshttp://pga.gs.washington.edu/data/fut1/
    Functional Glycomics Gateway - GTasehttp://www.functionalglycomics.org/glycomics/molecule/jsp/glycoEnzyme/viewGlycoEnzyme.jsp?gbpId=gt_hum_598

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for FUT1 gene:
    Search GeneIP for patents involving FUT1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 3 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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