External Ids for FUK Gene
Previous GeneCards Identifiers for FUK Gene
The protein encoded by this gene belongs to the GHMP (galacto-, homoserine, mevalonate and phosphomevalonate) kinase family and catalyzes the phosphorylation of L-fucose to form beta-L-fucose 1-phosphate. This enzyme catalyzes the first step in the utilization of free L-fucose in glycoprotein and glycolipid synthesis. L-fucose may be important in mediating a number of cell-cell interactions such as blood group antigen recognition, inflammation, and metastatis. While several transcript variants may exist for this gene, the full-length nature of only one has been described to date. [provided by RefSeq, Jul 2008]
GeneCards Summary for FUK Gene
FUK (Fucokinase) is a Protein Coding gene. Among its related pathways are Amino sugar and nucleotide sugar metabolism and Transport to the Golgi and subsequent modification. GO annotations related to this gene include transferase activity, transferring phosphorus-containing groups and phosphotransferase activity, alcohol group as acceptor.
UniProtKB/Swiss-Prot for FUK Gene
Takes part in the salvage pathway for reutilization of fucose from the degradation of oligosaccharides.