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Aliases for FTX Gene

Subcategory (RNA class) for FTX Gene

non-coding RNA

Quality Score for this RNA gene is


Aliases for FTX Gene

  • FTX Transcript, XIST Regulator (Non-Protein Coding) 2 3 5
  • Mir-374a-545 Cluster Host Gene (Non-Protein Coding) 2 3
  • Five Prime To XIST 2 3
  • Non-Protein Coding RNA 182 2
  • NCRNA00182 3
  • LINC00182 3
  • MIR374AHG 3

External Ids for FTX Gene

Previous HGNC Symbols for FTX Gene

  • NCRNA00182
  • MIR374AHG

Previous GeneCards Identifiers for FTX Gene

  • GC0XU990359
  • GC0XM073248
  • GC0XM073183

Summaries for FTX Gene

Entrez Gene Summary for FTX Gene

  • This gene is located upstream of XIST, within the X-inactivation center (XIC). It produces a spliced long non-coding RNA that is thought to positively regulate the expression of XIST, which is essential for the initiation and spread of X-inactivation. [provided by RefSeq, May 2015]

GeneCards Summary for FTX Gene

FTX (FTX Transcript, XIST Regulator (Non-Protein Coding)) is an RNA Gene, and is affiliated with the non-coding RNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FTX Gene

Genomics for FTX Gene

Regulatory Elements for FTX Gene

Enhancers for FTX Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH0XF073943 1.2 ENCODE 68.3 +349.0 349035 2.2 MLX YBX1 FEZF1 DMAP1 YY1 ZNF416 ZNF143 ZNF548 ZNF263 SP3 RAB11FIP1P1 ENSG00000271430 JPX FTX DDX3P1 ENSG00000271199 RN7SL648P TOMM20P4 ENSG00000228906 ENSG00000271533
GH0XF073850 1.1 ENCODE 18.5 +441.9 441900 2.3 PKNOX1 CREB3L1 SIN3A FEZF1 ZNF2 YY1 ZNF302 ZNF548 FOS ZNF263 RAB11FIP1P1 JPX ENSG00000271430 RN7SL648P TOMM20P4 FTX ZCCHC13 ENSG00000271533 ENSG00000234969 ENSG00000271199
GH0XF074342 1.3 Ensembl ENCODE 13.2 -50.1 -50072 1.9 HDGF WRNIP1 GLI4 FEZF1 ZNF2 ETS1 YY1 ZNF121 ZNF207 KLF7 ZCCHC13 FTX ENSG00000271533 ENSG00000226515 LOC727681
GH0XF074248 1.1 Ensembl ENCODE 12.9 +42.9 42911 5.1 ELF3 FEZF1 ZBTB40 ZNF121 ZEB2 ZNF843 SMARCA4 CEBPA GLIS1 KDM1A MIR374B MIR421 MIR374A MIR545 FTX JPX ENSG00000271430 GC0XP074249 ENSG00000278421
GH0XF074240 1.1 Ensembl ENCODE 12.7 +51.1 51148 3.0 ELF3 THRB RARA CREM MIXL1 ZNF263 PPARG CEBPA ETV4 SOX13 MIR374B MIR421 FTX ZCCHC13 MIR374A MIR545 JPX ENSG00000271430 RN7SL648P
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around FTX on UCSC Golden Path with GeneCards custom track

Genomic Location for FTX Gene

73,963,955 bp from pter
74,293,574 bp from pter
329,620 bases
Minus strand

Genomic View for FTX Gene

Genes around FTX on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
FTX Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for FTX Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for FTX Gene

Proteins for FTX Gene

Post-translational modifications for FTX Gene

No Post-translational modifications

No data available for DME Specific Peptides for FTX Gene

Domains & Families for FTX Gene

Gene Families for FTX Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with FTX: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for FTX Gene

Function for FTX Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for FTX Gene

Localization for FTX Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for FTX Gene

Pathways & Interactions for FTX Gene

No Data Available

Interacting Proteins for FTX Gene

Gene Ontology (GO) - Biological Process for FTX Gene


No data available for Pathways by source and SIGNOR curated interactions for FTX Gene

Transcripts for FTX Gene

mRNA/cDNA for FTX Gene

(4) Additional mRNA sequences :
(10) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for FTX Gene

FTX transcript, XIST regulator (non-protein coding):
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for FTX Gene

No ASD Table

Relevant External Links for FTX Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for FTX Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for FTX Gene

NURSA nuclear receptor signaling pathways regulating expression of FTX Gene:


SOURCE GeneReport for Unigene cluster for FTX Gene:

genes like me logo Genes that share expression patterns with FTX: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for FTX Gene

Orthologs for FTX Gene

Evolution for FTX Gene

Gene Tree for FTX (if available)
Gene Tree for FTX (if available)

No data available for Orthologs for FTX Gene

Paralogs for FTX Gene

No data available for Paralogs for FTX Gene

Variants for FTX Gene

Sequence variations from dbSNP and Humsavar for FTX Gene

SNP ID Clin Chr 0X pos Sequence Context AA Info Type
rs10218306 -- 74,205,902(+) CTCAC(A/G)GGCAT intron-variant
rs10482113 -- 74,146,923(+) ccagc(A/G)tgaat intron-variant
rs10786 -- 74,173,915(+) TGCGC(A/G)ATACC intron-variant
rs10855815 -- 74,097,355(+) caagt(C/T)tgtcc intron-variant
rs11093445 -- 74,052,834(+) ggacc(A/C)agcta intron-variant

Structural Variations from Database of Genomic Variants (DGV) for FTX Gene

Variant ID Type Subtype PubMed ID
esv2740225 CNV deletion 23290073
esv2740226 CNV deletion 23290073
esv2740227 CNV deletion 23290073

Relevant External Links for FTX Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for FTX Gene

Disorders for FTX Gene

Relevant External Links for FTX

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for FTX Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for FTX Gene

Publications for FTX Gene

  1. Ftx is a non-coding RNA which affects Xist expression and chromatin structure within the X-inactivation center region. (PMID: 21118898) Chureau C. … Rougeulle C. (Hum. Mol. Genet. 2011) 2 3 64
  2. [Comparative organization and the origin of noncoding regulatory RNA genes from X-chromosome inactivation center of human and mouse]. (PMID: 21254562) Kolesnikov N.N. … Elisafenko E.A. (Genetika 2010) 2 3 64
  3. Comparative sequence analysis of the X-inactivation center region in mouse, human, and bovine. (PMID: 12045143) Chureau C. … Duret L. (Genome Res. 2002) 2 3 64
  4. The miR-545/374a cluster encoded in the Ftx lncRNA is overexpressed in HBV-related hepatocellular carcinoma and promotes tumorigenesis and tumor progression. (PMID: 25299640) Zhao Q. … Qin C. (PLoS ONE 2014) 3 64
  5. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 64

Products for FTX Gene

Sources for FTX Gene

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