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FTSJ3 Gene

protein-coding   GIFtS: 53
GCID: GC17M061896

FtsJ Homolog 3 (E. Coli)

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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
FtsJ Homolog 3 (E. Coli)1 2     SPB12
Protein FtsJ Homolog 32 3     Pre-RRNA Processing Protein FTSJ32
Putative RRNA Methyltransferase 32 3     RRNA (Uridine-2'-O-)-Methyltransferase 32
2'-O-Ribose RNA Methyltransferase SPB1 Homolog2 3     SPB1 RNA Methyltransferase Homolog2
SPB1 RNA Methyltransferase Homolog (S. Cerevisiae)1     EC 2.1.1.-3
EPCS32     

External Ids:    HGNC: 171361   Entrez Gene: 1172462   Ensembl: ENSG000001085927   UniProtKB: Q8IY813   

Export aliases for FTSJ3 gene to outside databases

Previous GC identifers: GC17M061547 GC17M064323 GC17M062237 GC17M062370 GC17M059250 GC17M057264


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for FTSJ3 Gene:
Although the function of this gene is not known, the existence of this gene is supported by mRNA and EST data. A
possible function of the encoded protein can be inferred from amino acid sequence similarity to the E.coli FtsJ
protein and to a mouse protein possibly involved in embryogenesis. (provided by RefSeq, Jul 2008)

GeneCards Summary for FTSJ3 Gene:
FTSJ3 (FtsJ homolog 3 (E. coli)) is a protein-coding gene. GO annotations related to this gene include methyltransferase activity.

UniProtKB/Swiss-Prot: SPB1_HUMAN, Q8IY81
Function: Probable methyltransferase involved in the processing of the 34S pre-rRNA to 18S rRNA and in 40S
ribosomal subunit formation

Gene Wiki entry for FTSJ3 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000017.10  NC_018928.2  NT_010783.16  
Regulatory elements:
   Regulatory transcription factor binding sites in the FTSJ3 gene promoter:
         E2F-3a   E2F-4   E2F-5   POU2F1   Sp1   AML1a   E2F-2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidFTSJ3 promoter sequence
   Search Chromatin IP Primers for FTSJ3

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat FTSJ3


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 17q23.3   Ensembl cytogenetic band:  17q23.3   HGNC cytogenetic band: 17q23

FTSJ3 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
FTSJ3 gene location

GeneLoc information about chromosome 17         GeneLoc Exon Structure

GeneLoc location for GC17M061896:  view genomic region     (about GC identifiers)

Start:
61,896,793 bp from pter      End:
61,907,372 bp from pter
Size:
10,580 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: SPB1_HUMAN, Q8IY81 (See protein sequence)
Recommended Name: pre-rRNA processing protein FTSJ3  
Size: 847 amino acids; 96558 Da
Subunit: Interacts with NIP7
Sequence caution: Sequence=BAA90924.1; Type=Erroneous initiation; Note=Translation N-terminally extended;
Secondary accessions: B2RCA5 D3DU22 Q8N3A3 Q8WXX1 Q9BWM4 Q9NXT6

Explore the universe of human proteins at neXtProt for FTSJ3: NX_Q8IY81

Explore proteomics data for FTSJ3 at MOPED

Post-translational modifications: 

  • Citrullinated by PADI4 (By similarity)1
  • Ubiquitination2 at Lys214, Lys218, Lys710
  • Modification sites at PhosphoSitePlus

  • See FTSJ3 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_060117.3  
    ENSEMBL proteins: 
     ENSP00000396673   ENSP00000462212   ENSP00000462342   ENSP00000463980   ENSP00000462290  
     ENSP00000464648   ENSP00000464361   ENSP00000463229  

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    5 InterPro protein domains:
     IPR015507 rRNA-MeTfrase_E
     IPR024576 rRNA_MeTfrase_Spb1_DUF3381
     IPR012920 rRNA_MeTfrase_Spb1_C
     IPR028589 Spb1
     IPR002877 rRNA_MeTrfase_FtsJ_dom

    Graphical View of Domain Structure for InterPro Entry Q8IY81

    ProtoNet protein and cluster: Q8IY81

    2 Blocks protein domains:
    IPB002877 Cell division protein FtsJ
    IPB012920 Spb1


    UniProtKB/Swiss-Prot: SPB1_HUMAN, Q8IY81
    Similarity: Belongs to the methyltransferase superfamily. RlmE family. SPB1 subfamily


    Find genes that share domains with FTSJ3           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: SPB1_HUMAN, Q8IY81
    Function: Probable methyltransferase involved in the processing of the 34S pre-rRNA to 18S rRNA and in 40S
    ribosomal subunit formation
    Catalytic activity: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing
    2'-O-methylnucleoside

         Enzyme Number (IUBMB): EC 2.1.1.-1

         Gene Ontology (GO): 4 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI--
    GO:0008168methyltransferase activity ----
    GO:0008649rRNA methyltransferase activity IEA--
    GO:0044822poly(A) RNA binding IDA--
         
    Find genes that share ontologies with FTSJ3           About GenesLikeMe


    Animal Models:
       genOway: Develop your customized and physiologically relevant rodent model for FTSJ3

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    miRTarBase miRNAs that target FTSJ3:
    hsa-mir-330-5p (MIRT038257)

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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    SPB1_HUMAN, Q8IY81: Nucleus, nucleolus
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus5
    cytosol2
    golgi apparatus1

    Gene Ontology (GO): 2 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IDA--
    GO:0005730nucleolus IDA--

    Find genes that share ontologies with FTSJ3           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for FTSJ3
    Interactions:

        Search GeneGlobe Interaction Network for FTSJ3

    Selected Interacting proteins for FTSJ3 (Q8IY811, 2, 3) via UniProtKB, MINT, STRING, and/or I2D (see all 20)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    SAT1P216732, 3MINT-66444 I2D: score=4 
    EIF2AK2P195251, 3EBI-744088,EBI-640775 I2D: score=1 
    OAS3Q9Y6K51, 3EBI-744088,EBI-6115729 I2D: score=1 
    MAGEB4O154813I2D: score=3 
    CHN2P527573I2D: score=1 
    About this table

    Gene Ontology (GO): 2 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006364rRNA processing ----
    GO:0032259methylation ----

    Find genes that share ontologies with FTSJ3           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
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      Browse compounds at ApexBio 

    Browse Tocris compounds for FTSJ3 (SPB1)

    1 HMDB Compound for FTSJ3    About this table
    CompoundSynonyms CAS #PubMed Ids
    S-Adenosylmethionine(3S)-5'-[(3-amino-3-carboxypropyl)methylsulfonio]-5'-deoxyadenosine (see all 16)29908-03-0--



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for FTSJ3 gene: 
    NM_017647.3  

    Unigene Cluster for FTSJ3:

    FtsJ homolog 3 (E. coli)
    Hs.463785  [show with all ESTs]
    Unigene Representative Sequence: NM_017647
    16 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000427159(uc002jca.3) ENST00000583202 ENST00000583901 ENST00000579831
    ENST00000580376 ENST00000580129 ENST00000579569 ENST00000584193 ENST00000580272
    ENST00000581209 ENST00000577263 ENST00000580290 ENST00000582476 ENST00000584574
    ENST00000585145 ENST00000580295
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      QuantiTect SYBR Green Assays in human, mouse, rat FTSJ3
      QuantiFast Probe-based Assays in human, mouse, rat FTSJ3

    Additional mRNA sequence: 

    AF147378.1 AF327355.1 AK000069.1 AK095861.1 AK296715.1 AK307398.1 AK315010.1 AL834482.1 
    BC000131.1 BC036710.2 

    18 DOTS entries:

    DT.100745357  DT.100745437  DT.97855470  DT.86837221  DT.100724310  DT.91723560  DT.102838781  DT.95202158 
    DT.100745450  DT.121007096  DT.100745389  DT.92440817  DT.95070697  DT.121007354  DT.121007509  DT.95070700 
    DT.101964800  DT.102838780 

    11 AceView cDNA sequences:

    BC000131 CR614545 AK095861 AL834482 CR596573 NM_017647 BC036710 AK000069 
    AF327355 AF147378 AK027463 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for FTSJ3 (see all 13)    About this scheme

    ExUns: 1 ^ 2a · 2b ^ 3a · 3b · 3c ^ 4 ^ 5a · 5b ^ 6a · 6b · 6c · 6d ^ 7 ^ 8 ^ 9a · 9b ^ 10 ^ 11 ^ 12a · 12b ^ 13 ^ 14 ^ 15 ^ 16 ^ 17a ·
    SP1:                    -     -                 -                       -     -                                                                                 
    SP2:        -     -     -     -                 -                       -     -                                                                                 
    SP3:                                            -                       -     -                                                                                 
    SP4:                                                                                                                                                            
    SP5:                    -     -                 -                                                                                                               

    ExUns: 17b · 17c ^ 18 ^ 19 ^ 20 ^ 21 ^ 22 ^ 23a · 23b ^ 24
    SP1:                                                            
    SP2:                                                            
    SP3:                                                            
    SP4:                                                            
    SP5:                                                            


    ECgene alternative splicing isoforms for FTSJ3

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    FTSJ3 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: ACCCTTTTTT
    FTSJ3 Expression
    About this image


    FTSJ3 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 3) fully expand
     
     Brain (Nervous System)    fully expand to see all 4 entries
             Cerebral Cortex
     
     Ovary (Reproductive System)
             Oviduct
     
     Testis (Reproductive System)
             Leydig Cells Testis Interstitium
    FTSJ3 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    FTSJ3 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.463785
        Custom PCR Arrays for FTSJ3
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    In Situ
    Assay Products:
     

     
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of eukaryotes.

    Orthologs for FTSJ3 gene from Selected species (see all 19)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Ftsj31 , 5 FtsJ homolog 3 (E. coli)1, 5 85.25(n)1
    88.12(a)1
      11 (68.89 cM)5
    560951  NM_025310.21  NP_079586.11 
     1062491425 
    chicken
    (Gallus gallus)
    Aves FTSJ31 FtsJ homolog 3 (E. coli) 69.53(n)
    70.51(a)
      419943  NM_001030925.1  NP_001026096.1 
    lizard
    (Anolis carolinensis)
    Reptilia FTSJ36
    FtsJ homolog 3 (E. coli)
    65(a)
    1 ↔ 1
    6(71658369-71680206)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.34132 Xenopus laevis transcribed sequence with moderate similarity more 77.97(n)    BQ733528.1 
    zebrafish
    (Danio rerio)
    Actinopterygii wufa11d102 Danio rerio cDNA clone IMAGE5605243, partial cds 76.66(n)    BC055618.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG89391 , 3 rRNA processing rRNA methyltransferase3
    CG89391
    38(a)3
    51.96(n)1
    44.78(a)1
      14A53
    325681  NM_132871.31  NP_573099.11 
    worm
    (Caenorhabditis elegans)
    Secernentea H06I04.3a3   -- 55(a)
    (best of 2)
      III(3142371-3156867)   --
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes SPB16
    AdoMet-dependent methyltransferase involved in rRN...
    36(a)
    1 ↔ 1
    III(31449-33974) YCL054W
    rice
    (Oryza sativa)
    Liliopsida Os.203362 Oryza sativa (japonica cultivar-group) cDNA cloneJ more 74.83(n)    AK101119.1 


    ENSEMBL Gene Tree for FTSJ3 (if available)
    TreeFam Gene Tree for FTSJ3 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for FTSJ3 gene
    2 SIMAP similar genes for FTSJ3 using alignment to 8 protein entries:     SPB1_HUMAN (see all proteins):
    FTSJ1    FTSJ2

    Find genes that share paralogs with FTSJ3           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for FTSJ3 (see all 258)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 17 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1486782821,2
    F--61897255(+) CCTCTG/TACTCC 2 V syn11Minor allele frequency- T:0.00NA 4550
    rs1995649341,2
    --61897258(+) CTGACA/TCCAGC 2 G syn10--------
    rs2017550661,2
    C--61897290(+) CACACC/GTTTTT 2 R G mis11Minor allele frequency- G:0.00EU 1323
    rs2002421371,2
    C--61897343(+) CAGCCT/GTCTTG 2 /K /T mis11Minor allele frequency- G:0.00EU 1323
    rs2011906721,2
    C--61897344(+) AGCCTT/CCTTGT 2 /K /E mis11Minor allele frequency- C:0.00EU 1323
    rs1859738981,2
    C--61897459(+) ACTTTA/CTCTCG 2 E D mis10--------
    rs1906417561,2
    C--61897462(+) TTCTCG/TCGTTC 2 R syn10--------
    rs1156668251,2
    C,F--61897483(+) ACTGTG/CTTCAC 2 /N /K mis12Minor allele frequency- C:0.00WA NA 4772
    rs2005167321,2
    --61897553(+) GTCAGG/TTGACC 1 -- int10--------
    rs2001153141,2
    C--61897574(+) CCCCCA/C/TACCCC 1 -- int10--------

    HapMap Linkage Disequilibrium report for FTSJ3 (61896793 - 61907372 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 3 variations for FTSJ3:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv833510CNV Loss17160897
    nsv510720CNV Loss20534489
    nsv517272CNV Gain+Loss19592680

    Human Gene Mutation Database (HGMD): FTSJ3
    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing FTSJ3
    DNA2.0 Custom Variant and Variant Library Synthesis for FTSJ3

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    Find genes that share disorders with FTSJ3           About GenesLikeMe


    Export disorders for FTSJ3 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for FTSJ3 gene, integrated from 10 sources (see all 39):
    (articles sorted by number of sources associating them with FTSJ3)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. The human nucleolar protein FTSJ3 associates with NIP7 and functions in pre-rRNA processing. (PubMed id 22195017)1, 2 Morello L.G.... Zanchin N.I. (PLoS ONE 2011)
    2. A probability-based approach for high-throughput protein phosphorylation analysis and site localization. (PubMed id 16964243)1, 2 Beausoleil S.A.... Gygi S.P. (Nat. Biotechnol. 2006)
    3. Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)1, 2 Olsen J.V....Mann M. (Cell 2006)
    4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    6. Functional proteomic analysis of human nucleolus. (PubMed id 12429849)1, 2 Scherl A.... Diaz J.-J. (Mol. Biol. Cell 2002)
    7. The protein interaction landscape of the human CMGC kinase group. (PubMed id 23602568)1 Varjosalo M....Gstaiger M. (Cell Rep 2013)
    8. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (Cell 2012)
    9. Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (amp 2012)
    10. Targeted ubiquitination and degradation of G-protein-coupled receptor kinase 5 by the DDB1-CUL4 ubiquitin ligase complex. (PubMed id 22952844)1 Wu Z....Ma L. (PLoS ONE 2012)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 117246 HGNC: 17136 AceView: FTSJ3 Ensembl:ENSG00000108592 euGenes: HUgn117246
    ECgene: FTSJ3 H-InvDB: FTSJ3

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

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    NameDescription
    PharmGKB entry for FTSJ3 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for FTSJ3 gene:
    Search GeneIP for patents involving FTSJ3

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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