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Aliases for FTHL17 Gene

Aliases for FTHL17 Gene

  • Ferritin, Heavy Polypeptide-Like 17 2 3
  • Cancer/Testis Antigen 38 2 3 4
  • CT38 3 4
  • Ferritin Heavy Polypeptide-Like 17 3

External Ids for FTHL17 Gene

Previous GeneCards Identifiers for FTHL17 Gene

  • GC0XM029592
  • GC0XM029774
  • GC0XM030291
  • GC0XM030451
  • GC0XM030452
  • GC0XM030849
  • GC0XM028830

Summaries for FTHL17 Gene

Entrez Gene Summary for FTHL17 Gene

  • This gene is orthologous to a mouse gene that encodes a ferritin heavy polypeptide-like protein and shows testis-specific expression. [provided by RefSeq, Oct 2009]

GeneCards Summary for FTHL17 Gene

FTHL17 (Ferritin, Heavy Polypeptide-Like 17) is a Protein Coding gene. Diseases associated with FTHL17 include klinefelter's syndrome. GO annotations related to this gene include oxidoreductase activity and ferric iron binding. An important paralog of this gene is FTL.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FTHL17 Gene

Genomics for FTHL17 Gene

Regulatory Elements for FTHL17 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for FTHL17 Gene

31,071,241 bp from pter
31,072,053 bp from pter
813 bases
Minus strand

Genomic View for FTHL17 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for FTHL17 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for FTHL17 Gene

Proteins for FTHL17 Gene

  • Protein details for FTHL17 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Ferritin heavy polypeptide-like 17
    Protein Accession:
    Secondary Accessions:
    • Q6NT24
    • Q6NTE2

    Protein attributes for FTHL17 Gene

    183 amino acids
    Molecular mass:
    21142 Da
    Quaternary structure:
    No Data Available

neXtProt entry for FTHL17 Gene

Proteomics data for FTHL17 Gene at MOPED

Post-translational modifications for FTHL17 Gene

No Post-translational modifications

Other Protein References for FTHL17 Gene

ENSEMBL proteins:
REFSEQ proteins:

Antibody Products

No data available for DME Specific Peptides for FTHL17 Gene

Domains for FTHL17 Gene

Suggested Antigen Peptide Sequences for FTHL17 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Q9BXU8
  • Contains 1 ferritin-like diiron domain.
  • Belongs to the ferritin family.
genes like me logo Genes that share domains with FTHL17: view

No data available for Gene Families for FTHL17 Gene

Function for FTHL17 Gene

Gene Ontology (GO) - Molecular Function for FTHL17 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0008199 ferric iron binding IEA --
genes like me logo Genes that share ontologies with FTHL17: view

Phenotypes for FTHL17 Gene

GenomeRNAi human phenotypes for FTHL17:
genes like me logo Genes that share phenotypes with FTHL17: view

Animal Model Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for FTHL17

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for FTHL17 Gene

Localization for FTHL17 Gene

Subcellular locations from

Jensen Localization Image for FTHL17 Gene COMPARTMENTS Subcellular localization image for FTHL17 gene
Compartment Confidence
cytosol 2
extracellular 2

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for FTHL17 Gene

Pathways for FTHL17 Gene

SuperPathways for FTHL17 Gene

No Data Available

Interacting Proteins for FTHL17 Gene

Gene Ontology (GO) - Biological Process for FTHL17 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006826 iron ion transport IEA --
GO:0006879 cellular iron ion homeostasis IEA --
genes like me logo Genes that share ontologies with FTHL17: view

No data available for Pathways by source for FTHL17 Gene

Transcripts for FTHL17 Gene

mRNA/cDNA for FTHL17 Gene

(4) Selected AceView cDNA sequences:
(1) REFSEQ mRNAs :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for FTHL17

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for FTHL17 Gene

No ASD Table

Relevant External Links for FTHL17 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for FTHL17 Gene

mRNA expression in normal human tissues for FTHL17 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for FTHL17 Gene

This gene is overexpressed in Testis (51.7).

Protein differential expression in normal tissues for FTHL17 Gene

This gene is overexpressed in Tlymphocyte (53.1) and Brain (15.9).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for FTHL17 Gene

SOURCE GeneReport for Unigene cluster for FTHL17 Gene Hs.333125

mRNA Expression by UniProt/SwissProt for FTHL17 Gene

Tissue specificity: Testis specific. Also expressed in several cancers.
genes like me logo Genes that share expressions with FTHL17: view

Expression partners for FTHL17 Gene

In Situ Assay Products

Orthologs for FTHL17 Gene

This gene was present in the common ancestor of chordates.

Orthologs for FTHL17 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia FTHL17 35
  • 98.72 (n)
  • 96.17 (a)
FTHL17 36
  • 96 (a)
(Mus musculus)
Mammalia Fthl17 16
1600014K23Rik 36
  • 48 (a)
Fthl17 36
  • 54 (a)
Gm14458 36
  • 54 (a)
Gm14511 36
  • 56 (a)
Gm5634 36
  • 56 (a)
Gm5635 36
  • 56 (a)
(Bos Taurus)
Mammalia -- 36
  • 51 (a)
-- 36
  • 58 (a)
-- 36
  • 55 (a)
-- 36
  • 55 (a)
-- 36
  • 56 (a)
(Canis familiaris)
Mammalia -- 36
  • 51 (a)
-- 36
  • 42 (a)
-- 36
  • 50 (a)
(Monodelphis domestica)
Mammalia -- 36
  • 30 (a)
-- 36
  • 57 (a)
-- 36
  • 63 (a)
-- 36
  • 36 (a)
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 47 (a)
(Gallus gallus)
Aves FTH 36
  • 63 (a)
(Anolis carolinensis)
Reptilia -- 36
  • 64 (a)
(Danio rerio)
Actinopterygii fth1a 36
  • 55 (a)
fth1b 36
  • 55 (a)
Species with no ortholog for FTHL17:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for FTHL17 Gene

Gene Tree for FTHL17 (if available)
Gene Tree for FTHL17 (if available)

Paralogs for FTHL17 Gene

Paralogs for FTHL17 Gene

Selected SIMAP similar genes for FTHL17 Gene using alignment to 1 proteins: Pseudogenes for FTHL17 Gene

genes like me logo Genes that share paralogs with FTHL17: view

Variants for FTHL17 Gene

Sequence variations from dbSNP and Humsavar for FTHL17 Gene

SNP ID Clin Chr 0X pos Sequence Context AA Info Type MAF
rs375355 -- 31,070,776(+) AAAGA(A/G)GTACC downstream-variant-500B
rs377515 -- 31,073,951(-) accca(A/G)aatag upstream-variant-2KB
rs396951 -- 31,073,935(+) gcaga(A/G/T)attgc upstream-variant-2KB
rs397055 -- 31,073,858(-) gccag(G/T)gttgt upstream-variant-2KB
rs412823 -- 31,072,328(+) cagga(C/G)atgga upstream-variant-2KB

Relevant External Links for FTHL17 Gene

HapMap Linkage Disequilibrium report
Locus Specific Mutation Databases (LSDB)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for FTHL17 Gene

Disorders for FTHL17 Gene

MalaCards: The human disease database

MalaCards: The human disease database.

Search for FTHL17 Gene in MalaCards »

(1) Diseases for FTHL17 Gene including...

genes like me logo Genes that share disorders with FTHL17: view

No data available for OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for FTHL17 Gene

Publications for FTHL17 Gene

  1. An abundance of X-linked genes expressed in spermatogonia. (PMID: 11279525) Wang P.J. … Page D.C. (Nat. Genet. 2001) 2 3 4
  2. Five new human cancer-germline genes identified among 12 genes expressed in spermatogonia. (PMID: 12704671) Loriot A. … De Smet C. (Int. J. Cancer 2003) 3 4
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  4. Expression of cancer-testis antigens as possible targets for antigen-specific immunotherapy in head and neck squamous cell carcinoma. (PMID: 16929165) Atanackovic D. … Leuwer R. (Cancer Biol. Ther. 2006) 3
  5. Severe XIST hypomethylation clearly distinguishes (SRY+) 46,XX-maleness from Klinefelter syndrome. (PMID: 19812237) Poplinski A. … Gromoll J. (Eur. J. Endocrinol. 2010) 3

Products for FTHL17 Gene

Sources for FTHL17 Gene

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