FTH1 Gene
protein-coding GIFtS: 65
GCID: GC11M061731
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|
ferritin, heavy polypeptide 1
(Previous symbol: FTHL6)
| |
Aliases
for FTH1 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Ferritin, Heavy Polypeptide 11 2 | | Ferritin H Subunit2 3 | | FTHL61 2 3 5 | | EC 1.16.3.13 8 | | FTH1 2 3 | | Apoferritin1 | | FHC1 2 | | Ferritin Heavy Chain2 | | PIG151 2 | | Placenta Immunoregulatory Factor2 | | PLIF1 2 | | Proliferation-Inducing Protein 152 | | Cell Proliferation-Inducing Gene 15 Protein2 3 | | |
Export aliases for FTH1 gene to outside databasesPrevious GC identifers: GC11M064245 GC11M063307 GC11M061982 GC11M061507 GC11M061488 GC11M058061 |
Summaries
for FTH1 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for FTH1:
This gene encodes the heavy subunit of ferritin, the major intracellular iron storage protein in prokaryotes andeukaryotes. It is composed of 24 subunits of the heavy and light ferritin chains. Variation in ferritin subunitcomposition may affect the rates of iron uptake and release in different tissues. A major function of ferritin is thestorage of iron in a soluble and nontoxic state. Defects in ferritin proteins are associated with severalneurodegenerative diseases. This gene has multiple pseudogenes. Several alternatively spliced transcript variants havebeen observed, but their biological validity has not been determined. (provided by RefSeq, Jul 2008)
UniProtKB/Swiss-Prot: FRIH_HUMAN, P02794Function: Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Has ferroxidaseactivity. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. Also plays a rolein delivery of iron to cells. Mediates iron uptake in capsule cells of the developing kidney (By similarity)
Gene Wiki entry for FTH1
|
Genomic Views
for FTH1 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000011.9 NC_018922.1 NT_167190.1
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the FTH1 gene promoter:
RP58 STAT1 AP-1 Pax-5 Nkx2-5 Gfi-1 GATA-1 HSF2
Other transcription factors
Search SABiosciences Chromatin IP Primers for FTH1
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat FTH1 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 11q13 Ensembl cytogenetic band: 11q12.3 HGNC cytogenetic band: 11q13FTH1 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 11 GeneLoc Exon Structure GeneLoc location for GC11M061731: view genomic region
(about GC identifiers)
Start:
|
61,727,190 bp from pter |
End:
|
61,735,132 bp from pter |
Size:
|
7,943 bases |
Orientation:
|
minus strand |
|
Proteins
for FTH1 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: FRIH_HUMAN, P02794 (See
protein sequence)Recommended Name: Ferritin heavy chain Size: 183 amino acids; 21226 Da
Subunit: Oligomer of 24 subunits. There are two types of subunits: L (light) chain and H (heavy) chain. The major chaincan be light or heavy, depending on the species and tissue type. The functional molecule forms a roughly sphericalshell with a diameter of 12 nm and contains a central cavity into which the insoluble mineral iron core is deposited
Miscellaneous: In human liver the heavy chain is the major chain
Sequence caution: Sequence=AAI05803.1; Type=Erroneous initiation;
6/19 PDB 3D structures from  and Proteopedia  for FTH1 (see all 19):1FHA (3D)
2CEI (3D)
2CHI (3D)
2CIH (3D)
2CLU (3D)
2CN6 (3D)
Secondary accessions: B3KNR5 Q3KRA8 Q3SWW1Explore the universe of human proteins at neXtProt for FTH1: NX_P02794
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_P02794
4/12 DME Specific Peptides for FTH1 (P02794) (see all 12)
FTH1 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_002023.2
ENSEMBL proteins: ENSP00000431659 ENSP00000431575 ENSP00000433470 ENSP00000273550 ENSP00000432223 ENSP00000434403 ENSP00000433321 ENSP00000435111 ENSP00000436947 Reactome Protein details: P02794
Human Recombinant Protein Products:
Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view): About this table
FTH1 for ontologies About GeneDecksing
FTH1 Antibody Products:
Assay Products for FTH1: |
Protein
Domains /
Families
for FTH1 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
FTH1 for domains About GeneDecksing
5/6 InterPro domains/families (see all 6):Graphical View of Domain Structure for InterPro Entry P02794ProtoNet protein and cluster: P02794 3 Blocks protein families: IPB001519 Ferritin IPB008331 Ferritin and Dps IPB014034 Ferritin
UniProtKB/Swiss-Prot: FRIH_HUMAN, P02794Similarity: Belongs to the ferritin familySimilarity: Contains 1 ferritin-like diiron domain |
Function
for FTH1 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: FRIH_HUMAN, P02794Function: Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Has ferroxidaseactivity. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. Also plays a rolein delivery of iron to cells. Mediates iron uptake in capsule cells of the developing kidney (By similarity)Catalytic activity: 4 Fe(2+) + 4 H(+) + O(2) = 4 Fe(3+) + 2 H(2)O Genatlas biochemistry entry for FTH1:ferritin,heavy polypeptide 1,21.1kDa,liver-like,isolated from brain,iron-storage protein,with a 3'utr containing aregion of antisense complementarity to the 3' end of VMD2
Enzyme Number (IUBMB): EC 1.16.3.11 2
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for FTH1 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for FTH1
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: FTH1 (NM_002032) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for FTH1 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FTH1 |
Gene Ontology (GO): 5 molecular function terms (GO ID links to tree view): About this table
FTH1 for ontologies About GeneDecksing
Animal Models:
Mouse knock-outs for FTH1: Fth1tm1.2Lck Fth1tm1Kjt
8 MGI mutant phenotypes (inferred from 5 alleles ) (MGI details for Fth1):
FTH1 for phenotypes About GeneDecksing
|
Pathways & Interactions
for FTH1 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways - 5/9 super-pathways (see all 9) About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Clathrin derived vesicle budding | | | 2 | Membrane Trafficking | | | 3 | iron metabolism in placenta | | | 4 | Validated targets of C-MYC transcriptional repression | | | 5 | Mineral absorption | |
Pathway sources
See GeneCards unified pathways
Show all pathways
1 
Cell Signaling Technology (CST) Pathway for FTH1
2  BioSystems Pathways for FTH1
5/6 
Reactome Pathways for FTH1 (see all 6)
2 
Kegg Pathways (Kegg details for FTH1):
FTH1 for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for FTH1
STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)
5/72 Interacting proteins for FTH1 (P027941, 2, 3 ENSP000002735504) via UniProtKB, MINT, STRING, and/or I2D (see all 72)About this table
Gene Ontology (GO): 5/10 biological process terms (GO ID links to tree view) (see all 10): About this table
FTH1 for ontologies About GeneDecksing
|
Drugs & Compounds
for FTH1 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
FTH1 for compounds About GeneDecksing
 Browse Tocris compounds for FTH1
4 HMDB Compounds for FTH1 About this table
1 DrugBank Compound for FTH1 About this table
10/24 Novoseek chemical compound relationships for FTH1 gene (see all 24) About this table
| Compound |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| ferrihydrite |
73 |
4 |
1764477 (1), 8422424 (1), 15826089 (1), 7738539 (1) |
| iron |
69.8 |
67 |
9518065 (3), 7951057 (2), 12504902 (2), 7738177 (2) (see all 34) |
| ferrous ammonium sulfate |
69.5 |
5 |
1536576 (4) |
| apotransferrin |
54.2 |
1 |
8464361 (1) |
| deferoxamine |
51.3 |
26 |
14987847 (6), 9518065 (1), 16140207 (1) |
| h2o2 |
38.7 |
6 |
9518065 (1), 11535059 (1), 8221666 (1), 18164668 (1) (see all 5) |
| ferricyanide |
37.7 |
7 |
17073407 (1), 14577762 (1) |
| fe2+ |
35 |
1 |
1679940 (1) |
| hepes |
30 |
3 |
1770974 (1), 11595385 (1) |
| halothane |
22.1 |
2 |
15791007 (1) |
Search CenterWatch for drugs/clinical trials and news about FTH1 / FRIH
|
Transcripts
for FTH1 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for FTH1 gene: NM_002032.2 Unigene Clusters for FTH1: Ferritin, heavy polypeptide 1 Hs.524910 [show with all ESTs], Hs.645560 Unigene Representative Sequences: BM905227, BC10580211 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000529191 ENST00000529631 ENST00000530019 ENST00000273550(uc001nsu.3)
ENST00000532829 ENST00000534180 ENST00000526640 ENST00000532601 ENST00000534719
ENST00000533138 ENST00000529548
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for FTH1 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for FTH1
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: FTH1 (NM_002032) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for FTH1 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FTH1 |
Additional cDNA sequence: BC105802.1 24/196 DOTS entries (see all 196): DT.100736732 DT.92056926 DT.421032 DT.91913296 DT.97867955 DT.100736743 DT.91740037 DT.100736685 DT.92017084 DT.100870650 DT.100060605 DT.100736736 DT.100034995 DT.91913590 DT.92030996 DT.95365175 DT.100042429 DT.91913682 DT.100854029 DT.100736690 DT.95269284 DT.101988005 DT.100736720 DT.100637411 24/360 AceView cDNA sequences (see all 360): CD369558 BC000857 BC013724 D28463 CR592751 CR608224 AI630450 BC073750 BM696376 M11146 BC011359 AW576106 AA111970 BQ352663 AI752260 BQ349137 CR610503 CB069374 BM508193 BU736834 AI752437 CR626495 M15383 BC070494
GeneLoc Exon Structure
3 Alternative Splicing Database (ASD) splice patterns (SP) for FTH1 About this scheme
| ExUns: | 1a | · | 1b | ^ | 2 | ^ | 3a | · | 3b | ^ | 4 | ^ | 5 |
|---|
|
| SP1: | | | | | | | | | | | | | | | |
| SP2: | | | | | | | - | | | | | | | | |
| SP3: | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for FTH1
|
Expression
for FTH1 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| FTH1 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TTGGGGTTTC
About this image
See FTH1 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for FTH1
SOURCE GeneReport for Unigene clusters: Hs.524910 Hs.645560
SABiosciences Expression via Pathway-Focused PCR Arrays including FTH1:
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for FTH1
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat FTH1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat FTH1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat FTH1 |
Orthologs
for FTH1 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the last universal common ancestor (LUCA).
Orthologs for FTH1 gene from 9/26 species (see all 26) About this table
ENSEMBL Gene Tree for FTH1 (if available)
TreeFam Gene Tree for FTH1 (if available) |
Paralogs
for FTH1 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for FTH1 gene
- FTHL172 FTMT2 FTL2
5 SIMAP similar genes for FTH1 using alignment to 12 protein entries: FRIH_HUMAN (see all proteins):FTMT FTH1P19 FTHL17 FTL variant FTL
FTH1 for paralogs About GeneDecksing
5/27 Pseudogenes.org Pseudogenes for FTH1 (see all 27)
PGOHUM00000248325 PGOHUM00000247834 PGOHUM00000258072 PGOHUM00000258079 PGOHUM00000244675
|
Genomic Variants
for FTH1 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 11 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for FTH1 (61727190 - 61735132 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for FTH1: --
Human Gene Mutation Database (HGMD): FTH1
| SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing FTH1 |
|
Disorders
/ Diseases
for FTH1 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Novoseek,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
FTH1 for disorders About GeneDecksing
OMIM gene information: 134770
OMIM disorders: --
20/55  diseases for FTH1 (see all 55): About MalaCardsiron overload, autosomal dominant neurodegenerative disease iron overload superficial siderosis of the central nervous system
porphyria cutanea tarda immune-complex glomerulonephritis triple-a syndrome hypersensitivity reaction type ii disease
spinal stenosis degenerative disc disease hemophagocytic lymphohistiocytosis siderosis
type 2 diabetes mellitus sickle cell anemia epithelioid sarcoma allergic encephalomyelitis
hemosiderosis spondylolisthesis diabetes mellitus radiculopathy
3 diseases from the University of Copenhagen DISEASES database for FTH1:Spondylolisthesis Glomerulonephritis Degenerative disc disease 4 Novoseek disease relationships for FTH1 gene About this table
| Disease |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| serum sickness |
50.9 |
2 |
15574507 (1), 17344423 (1) |
| iron overload |
27.3 |
2 |
1581551 (1), 8009283 (1) |
| tumors |
4.38 |
1 |
10554036 (1) |
| breast cancer |
0 |
1 |
11821435 (1) |
Genetic Association Database (GAD): FTH1
Human Genome Epidemiology (HuGE) Navigator: FTH1 (3 documents)
Export disorders for FTH1 gene to outside databases
|
Publications
for FTH1 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for FTH1 gene, integrated from 9 sources (see all 226):
(articles sorted by number of sources associating them with FTH1) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Cloning, characterization, expression, and chromosomal localization of a human ferritin heavy-chain gene. (PubMed id 3020541)1, 2, 3 Hentze M.W.... Klausner R.D. (1986)
- Sequence of a cDNA encoding the ferritin H-chain from an 11-week-old human fetal brain. (PubMed id 7916709)1, 2, 9 Dhar M.... Joshi J.G. (1993)
- Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)1, 2 Olsen J.V....Mann M. (2006)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Screening for mutations of the ferritin light and heavy genes in Parkinson's disease patients with hyperechogenicity of the substantia nigra. (PubMed id 14615048)1, 4 Felletschin B....Berg D. (2003)
- Comparison of the three-dimensional structures of recombinant human H and horse L ferritins at high resolution. (PubMed id 9159481)1, 2 Hempstead P.D.... Harrison P.M. (1997)
- Solving the structure of human H ferritin by genetically engineering intermolecular crystal contacts. (PubMed id 1992356)1, 2 Lawson D.M.... Harrison P.M. (1991)
- Structure and expression of ferritin genes in a human promyelocytic cell line that differentiates in vitro. (PubMed id 3023856)1, 2 Chou C.-C.... Salser W.A. (1986)
- Structure of gene and pseudogenes of human apoferritin H. (PubMed id 3003694)1, 2 Costanzo F.... Cortese R. (1986)
|
External Searches for FTH1 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing FTH1 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing FTH1 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing FTH1 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for FTH1 | Pharmacogenomics, SNPs, Pathways | | Wikipedia | http://en.wikipedia.org/wiki/Ferritin |
|
| | |
About This Section
| Patent Information for FTH1 gene:
Search GeneIP for patents involving FTH1
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for FTH1 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
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| | |  | OriGene Antibodies for FTH1 | | Browse OriGene shRNA RFPs | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for FTH1 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for FTH1 | | | OriGene Protein Over-expression Lysate for FTH1 | | Browse OriGene Fluorogenic Cell Assay Kits | | | Browse OriGene siRNAs | | OriGene 3'-UTR Clone for FTH1 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for FTH1 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for FTH1 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for FTH1 | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for FTH1 | | OriGene Custom Protein Services for FTH1 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat FTH1 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing FTH1 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat FTH1 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat FTH1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat FTH1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat FTH1 |
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| | Antibodies & Assays for FTH1
(ferritin H) |
| | | | Search Tocris compounds for FTH1 |
| |  |  |  |  | | | | | | Recombinant Protein for FTH1 |
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 | | | FTH1 Proteins, Antibodies, CLIAs, and ELISAs |
| | | |  |  |  | | | | ThermoFisher Antibodies for FTH1 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FTH1 |
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