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Aliases for FTCDNL1 Gene

Subcategory (RNA class) for FTCDNL1 Gene


Quality Score for this RNA gene is


Aliases for FTCDNL1 Gene

  • Formiminotransferase Cyclodeaminase N-Terminal Like 2 3
  • FONG 3 4 6
  • Formiminotransferase-Cyclodeaminase N-Terminal-Like Protein 4
  • Formiminotransferase N-Terminal Sub-Domain Containing Gene 2
  • Formiminotransferase N-Terminal Sub-Domain Containing 3

External Ids for FTCDNL1 Gene

Previous GeneCards Identifiers for FTCDNL1 Gene

  • GC02M200628

Summaries for FTCDNL1 Gene

GeneCards Summary for FTCDNL1 Gene

FTCDNL1 (Formiminotransferase Cyclodeaminase N-Terminal Like) is an RNA Gene, and is affiliated with the ncRNA class. GO annotations related to this gene include transferase activity and folic acid binding. An important paralog of this gene is FTCD.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FTCDNL1 Gene

Genomics for FTCDNL1 Gene

Genomic Location for FTCDNL1 Gene

199,760,536 bp from pter
199,851,173 bp from pter
90,638 bases
Minus strand

Genomic View for FTCDNL1 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for FTCDNL1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for FTCDNL1 Gene

No data available for Regulatory Elements for FTCDNL1 Gene

Proteins for FTCDNL1 Gene

  • Protein details for FTCDNL1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Formiminotransferase N-terminal subdomain-containing protein
    Protein Accession:
    Secondary Accessions:

    Protein attributes for FTCDNL1 Gene

    147 amino acids
    Molecular mass:
    16268 Da
    Quaternary structure:
    No Data Available

neXtProt entry for FTCDNL1 Gene

Proteomics data for FTCDNL1 Gene at MOPED

Post-translational modifications for FTCDNL1 Gene

No Post-translational modifications

Other Protein References for FTCDNL1 Gene

No data available for DME Specific Peptides for FTCDNL1 Gene

Domains for FTCDNL1 Gene

Protein Domains for FTCDNL1 Gene

Graphical View of Domain Structure for InterPro Entry



  • E5RQL4
  • Belongs to the formiminotransferase family.
genes like me logo Genes that share domains with FTCDNL1: view

No data available for Gene Families and Suggested Antigen Peptide Sequences for FTCDNL1 Gene

Function for FTCDNL1 Gene

Gene Ontology (GO) - Molecular Function for FTCDNL1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005542 folic acid binding IEA --
GO:0016740 transferase activity IEA --
genes like me logo Genes that share ontologies with FTCDNL1: view

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for FTCDNL1 Gene

Localization for FTCDNL1 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for FTCDNL1 Gene

Pathways for FTCDNL1 Gene

SuperPathways for FTCDNL1 Gene

No Data Available

Interacting Proteins for FTCDNL1 Gene

Gene Ontology (GO) - Biological Process for FTCDNL1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0008152 metabolic process IEA --
genes like me logo Genes that share ontologies with FTCDNL1: view

No data available for Pathways by source for FTCDNL1 Gene

Transcripts for FTCDNL1 Gene

mRNA/cDNA for FTCDNL1 Gene

(4) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for FTCDNL1

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for FTCDNL1 Gene

No ASD Table

Relevant External Links for FTCDNL1 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for FTCDNL1 Gene

mRNA expression in normal human tissues for FTCDNL1 Gene

mRNA differential expression in normal tissues according to GTEx for FTCDNL1 Gene

This gene is overexpressed in Muscle - Skeletal (4.3).

mRNA Expression by UniProt/SwissProt for FTCDNL1 Gene

Tissue specificity: Widely expressed with highest levels in liver and skeletal muscle, and moderate levels in kidney, bone and pancreas.
genes like me logo Genes that share expressions with FTCDNL1: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression and Expression partners for FTCDNL1 Gene

Orthologs for FTCDNL1 Gene

This gene was present in the common ancestor of chordates.

Orthologs for FTCDNL1 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia FTCDNL1 36
  • 30 (a)
(Monodelphis domestica)
Mammalia -- 36
  • 23 (a)
-- 36
  • 33 (a)
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 6 (a)
(Gallus gallus)
Aves FTCD 36
  • 6 (a)
(Anolis carolinensis)
Reptilia FTCDNL1 36
  • 23 (a)
(Danio rerio)
Actinopterygii FTCDNL1 36
  • 21 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 6 (a)
Species with no ortholog for FTCDNL1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for FTCDNL1 Gene

Gene Tree for FTCDNL1 (if available)
Gene Tree for FTCDNL1 (if available)

Paralogs for FTCDNL1 Gene

Paralogs for FTCDNL1 Gene

genes like me logo Genes that share paralogs with FTCDNL1: view

Variants for FTCDNL1 Gene

Sequence variations from dbSNP and Humsavar for FTCDNL1 Gene

SNP ID Clin Chr 02 pos Sequence Context AA Info Type MAF
rs717915 -- 199,850,043(+) GCTCT(C/T)CCTCA intron-variant
rs769954 -- 199,827,436(+) ATAAA(C/G)AGATA intron-variant
rs769955 -- 199,827,872(+) GCTCC(C/T)ATATT intron-variant
rs769956 -- 199,828,997(+) AGAGT(A/G)GTGGT intron-variant
rs769957 -- 199,830,801(+) ACATC(A/C)TTGAG intron-variant

Relevant External Links for FTCDNL1 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for FTCDNL1 Gene

Disorders for FTCDNL1 Gene

No disorders were found for FTCDNL1 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for FTCDNL1 Gene

Publications for FTCDNL1 Gene

  1. Common variants in a novel gene, FONG on chromosome 2q33.1 confer risk of osteoporosis in Japanese. (PMID: 21573128) Kou I. … Ikegawa S. (PLoS ONE 2011) 2 3 4
  2. Association of the formiminotransferase N-terminal sub-domain containing gene and thrombospondin, type 1, domain-containing 7A gene with the prevalence of vertebral fracture in 2427 consecutive autopsy cases. (PMID: 23303384) Zhou H. … Ito H. (J. Hum. Genet. 2013) 3
  3. Genome-wide association study of chemotherapeutic agent-induced severe neutropenia/leucopenia for patients in Biobank Japan. (PMID: 23648065) Low S.K. … Nakamura Y. (Cancer Sci. 2013) 3
  4. Genome-wide association analysis identifies 13 new risk loci for schizophrenia. (PMID: 23974872) Ripke S. … Sullivan P.F. (Nat. Genet. 2013) 3
  5. Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PMID: 15815621) Hillier L.W. … Wilson R.K. (Nature 2005) 4

Products for FTCDNL1 Gene

Sources for FTCDNL1 Gene

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