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Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

FSTL4 Gene

protein-coding GIFtS: 49
GCID: GC05M132560

follistatin-like 4

Search for FSTL4
in

MalaCards

our new
Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

Aliases
Follistatin-Like 4¹ ²
KIAA1061¹ ³
Follistatin-Like Protein 4² ³
Follistatin-Related Protein 4²

External Ids:	HGNC: 21389¹	Entrez Gene: 23105²	Ensembl: ENSG00000053108⁷	UniProtKB: Q6MZW2³

Export aliases for FSTL4 gene to outside databases

Previous GC identifers: GC05M132609 GC05M127723

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000005.9 NC_018916.1 NT_034772.6

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the FSTL4 gene promoter:
c-Fos JunB Fra-1 FosB MyoD C/EBPalpha Pax-3 FOXO1a c-Jun FOXO1
Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: FSTL4 promoter sequence

Search SABiosciences Chromatin IP Primers for FSTL4

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat FSTL4

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 5q31.1 Ensembl cytogenetic band: 5q31.1 HGNC cytogenetic band: 5q31.1

FSTL4 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
FSTL4 gene location

GeneLoc information about chromosome 5 GeneLoc Exon Structure

GeneLoc location for GC05M132560: view genomic region (about GC identifiers)

Start:	132,532,147 bp from pter	End:	132,948,255 bp from pter
Size:	416,109 bases	Orientation:	minus strand

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: FSTL4_HUMAN, Q6MZW2 (See protein sequence)

Recommended Name: Follistatin-related protein 4 precursor

Size: 842 amino acids; 93096 Da

Subcellular location: Secreted (Probable)

Secondary accessions: Q8TBU0 Q9UPU1

Alternative splicing: 3 isoforms: Q6MZW2-1 Q6MZW2-2 Q6MZW2-3 (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for FSTL4: NX_Q6MZW2

Post-translational modifications:

View modification sites using PhosphoSitePlus²

View neXtProt modification sites for NX_Q6MZW2

FSTL4 Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins: NP_055897.1

ENSEMBL proteins:

ENSP00000265342 ENSP00000427662

Human Recombinant Protein Products for FSTL4:

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	Uscn Proteins for FSTL4

Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005576	extracellular region	IEA	--

FSTL4 for ontologies About GeneDecksing

FSTL4 Antibody Products:

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	Uscn ELISAs and CLIAs for FSTL4

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

FSTL4 for domains About GeneDecksing

5/10 InterPro domains/families (see all 10):

IPR003598 Ig_sub2

IPR002350 Prot_inh_Kazal

IPR011992 EF-hand-like_dom

IPR002048 EF_hand_Ca-bd

IPR013098 Ig_I-set

Graphical View of Domain Structure for InterPro Entry Q6MZW2

ProtoNet protein and cluster: Q6MZW2

3 Blocks protein families:

IPB003598 Immunoglobulin C-2 type

IPB003599 Immunoglobulin subtype

IPB013098 Immunoglobulin I-set

UniProtKB/Swiss-Prot: FSTL4_HUMAN, Q6MZW2

Similarity: Contains 1 EF-hand domain

Similarity: Contains 2 Ig-like (immunoglobulin-like) domains

Similarity: Contains 1 Kazal-like domain

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, Sirion Biotech, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, Sirion Biotech, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

Gene Ontology (GO): 1 molecular function term (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005509	calcium ion binding	IEA	--

FSTL4 for ontologies About GeneDecksing

Phenotypes:
1 GenomeRNAi human phenotype for FSTL4:

Increased cell number in G2M,

1 MGI mutant phenotype (inferred from 1 allele) (MGI details for Fstl4):

normal

FSTL4 for phenotypes About GeneDecksing

Animal Models:

inGenious Targeting Laboratory - Customizable classic, inducible, and humanized mouse model solutions for FSTL4

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		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat FSTL4
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		SwitchGear 3'UTR luciferase reporter plasmid: FSTL4 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
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In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FSTL4

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Interactions:

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for FSTL4

STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

1 Interacting protein for FSTL4 (ENSP00000265342⁴) via UniProtKB, MINT, STRING, and/or I2D

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
UBC	ENSP00000344818⁴	STRING: ENSP00000344818

About this table

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for FSTL4
Search CenterWatch for drugs/clinical trials and news about FSTL4

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, Sirion Biotech, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for FSTL4 gene:

NM_015082.1

Unigene Cluster for FSTL4:

Follistatin-like 4

Hs.483390 [show with all ESTs]

Unigene Representative Sequence: NM_015082

6 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000265342(uc003kym.1 uc003kyn.1) ENST00000509525 ENST00000511375

ENST00000507112 ENST00000514998 ENST00000510685

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		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat FSTL4
		8/50 QIAGEN miScript miRNA Assays for microRNAs that regulate FSTL4 (see all 50):
		hsa-miR-142-5p hsa-miR-3607-3p hsa-miR-106a hsa-miR-503 hsa-let-7a-2* hsa-miR-346 hsa-miR-632 hsa-miR-124

		SwitchGear 3'UTR luciferase reporter plasmid: FSTL4 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for FSTL4 (see all 7) OriGene shRNA RFP: FSTL4 OriGene siRNA: FSTL4
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat FSTL4
		Sirion Biotech Custom design and validation of potent shRNA sequences against FSTL4

Clone Products:		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for FSTL4 (see all 3) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for FSTL4 (see all 2) OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
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		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat FSTL4
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Additional cDNA sequence:

AB028984.1 AK026109.1 AK055684.1 AK056284.1 BC024300.1 BX640845.1

6 DOTS entries:

DT.203750 DT.100745134 DT.95080111 DT.120799696 DT.75118658 DT.102832166

24/38 AceView cDNA sequences (see all 38):

BX281824 BM712071 AK055684 BM504143 BQ082060 BQ955139 BM931134 AB028984

BU071076 AW627505 AA813585 BM670359 AW630123 AA600133 AI913177 BQ081869

AI808009 BG054507 AA922219 AK056284 BM504366 AA904974 AW197697 BC024300

GeneLoc Exon Structure

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

FSTL4 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GAACCAAGGG

About this image

FSTL4 expression in embryonic tissues and stem cells
Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine About this table

1 LifeMap In Vivo Development Anatomical Compartment/Cell

Tissue

Anatomical Compartment

Cell

Category (developmental path)

Eye

Retina

Eye

Expression:

Positive

Negative

Selective marker

Experimental details:

Curated

Microarrays

In-situ hybridization

See FSTL4 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for FSTL4

SOURCE GeneReport for Unigene cluster: Hs.483390

SABiosciences Custom PCR Arrays for FSTL4

Primer Products:		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for FSTL4 Browse OriGene validated miRNA SYBR primer pairs
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		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat FSTL4
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat FSTL4

In Situ
Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FSTL4

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of animals.

Orthologs for FSTL4 gene from 5/15 species (see all 15) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
mouse (Mus musculus)	Mammalia	Fstl4^{1 , 5}	follistatin-like 4^{1, 5}	84.15(n)¹ 83.83(a)¹		11 (31.86 cM)⁵ 320027¹ NM_177059.3¹ NP_796033.2¹ 52764634⁵
chicken (Gallus gallus)	Aves	FSTL4¹	follistatin-like 4	71.37(n) 69.12(a)		395163 NM_204502.1 NP_989833.1
lizard (Anolis carolinensis)	Reptilia	FSTL4⁶	--	69(a)	1 ↔ 1	2(129278857-129364734)
zebrafish (Danio rerio)	Actinopterygii	fstl4¹	follistatin-like 4	61.7(n) 55.92(a)		571664 NM_001031843.1 NP_001027013.1
honey bee (Apis mellifera)	Insecta	MAHYA⁶	--	31(a)	1 → many	Group12.10(537977-542462)

ENSEMBL Gene Tree for FSTL4 (if available)
TreeFam Gene Tree for FSTL4 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for FSTL4 gene

FSTL1² FSTL5²

6 SIMAP similar genes for FSTL4 using alignment to 2 protein entries: FSTL4_HUMAN (see all proteins):

DKFZp566D234 FSTL5 FSTL1 FST tmp_locus_3 AGRN

FSTL4 for paralogs About GeneDecksing

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 5 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs80283624^1,2	C	--	127731041(+)	`AAAGAA/TAGATA`	1	--	int¹		0	--	--	--	--
rs10707661^1,2	C	--	127763466(+)	`TCAGG-/AAAAAA`	1	--	int¹ trp³		2		NA CSA	4
rs200375909^1,2	C	--	127779678(-)	`CAGACC/TTGCCT`	1	--	int¹		0	--	--	--	--
rs191618302^1,2		--	132531681(+)	`GAATTG/TTAGGG`	1	--	ds500¹		0	--	--	--	--
rs61168871^1,2	C,F	--	132531840(+)	`TGAAGA/TAATAA`	1	--	ds500¹		5		NA WA EA	246
rs146705492^1,2		--	132531867(+)	`GGCAGG/TGTGGG`	1	--	ds500¹		0	--	--	--	--
rs62374509^1,2	C	--	132531888(+)	`GTTGGT/CGAGGC`	1	--	ds500¹		2		NA	122
rs55685127^1,2	C	--	132531967(+)	`GTCCCG/AAAGCT`	1	--	ds500¹		2		WA	120
rs139217011^1,2		--	132531996(+)	`CATCCA/GTCTGG`	1	--	ds500¹		0	--	--	--	--
rs57352224^1,2	C,F	--	132532002(+)	`TCTGGG/AGCTGC`	1	--	ds500¹		6		NA WA EA	248

HapMap Linkage Disequilibrium report for FSTL4 (132532147 - 132782147 bp, first 250kb of FSTL4)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 10 variations for FSTL4
8 CNVs: 36345 51572 22666 62434 43604 99301 69202 44186
2 Indels: 69203 60559
Human Gene Mutation Database (HGMD): FSTL4

SABiosciences Cancer Mutation PCR Assays

QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing FSTL4

DNA2.0 Custom Variant and Variant Library Synthesis for FSTL4

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

FSTL4 for disorders About MalaCards

FSTL4 for disorders About GeneDecksing

Human Genome Epidemiology (HuGE) Navigator: FSTL4 (3 documents)

Export disorders for FSTL4 gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
About This Section

PubMed articles for FSTL4 gene, integrated from 9 sources (see all 13):
(articles sorted by number of sources associating them with FSTL4)

Utopia: connect your pdf to the dynamic
world of online information

An enigmatic fourth runt domain gene in the fugu genome: ancestral gene loss versus accelerated evolution. (PubMed id 15527507)^{1, 2, 3} Glusman G.... Rowen L. (2004)
Prediction of the coding sequences of unidentified human genes. XIV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 10470851)^{1, 2, 3} Kikuno R....Ohara O. (1999)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{1, 2} Gerhard D.S....Malek J. (2004)
A genome-wide linkage and association scan reveals nov el loci for hypertension and blood pressure traits. (PubMed id 22384028)¹ Guo Y....Thomas N.G. (2012)
Ubiquitin ligase substrate identification through qua ntitative proteomics at both the protein and peptide levels. (PubMed id 21987572)¹ Lee K.A....Doedens J.R. (2011)
Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)¹ Rose J.E....Uhl G.R. (2010)
Gene variants associated with ischemic stroke: the cardiovascular health study. (PubMed id 19023099)¹ Luke M.M....Psaty B.M. (2009)
Association of gene variants with incident myocardial infarction in the Cardiovascular Health Study. (PubMed id 17975119)¹ Shiffman D....Psaty B.M. (2008)
Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls. (PubMed id 17554300)¹ . (2007)
The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005)² Bechtel S.... Schupp I. (2007)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section

Entrez Gene: 23105	HGNC: 21389	AceView: FSTL4	Ensembl:ENSG00000053108	euGenes: HUgn23105
ECgene: FSTL4	H-InvDB: FSTL4

(According to HUGE)
About This Section

HUGE: KIAA1061

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
PharmGKB entry for FSTL4	Pharmacogenomics, SNPs, Pathways

Intellectual Property for FSTL4 gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

About This Section

Patent Information for FSTL4 gene:
Search GeneIP for patents involving FSTL4

GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search

(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
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	EMD Millipore Custom Antibody & Bulk Services
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	Antibodies for FSTL4 (Follistatin-like 4/FSTL4)		Browse Cell Culture Products
	Browse ELISAs		Browse Flow Cytometry Kits
	Browse Primer Pairs		Browse Kinase Activity Assays/Reagents
	Browse ELISpot Kits/Development Modules		Browse TFB/Immunoprecipitation Assays
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	Browse Cell Selection/Detection Kits/Reagents		Browse Secondary Antibodies/Controls/Staining Reagents
	Browse Phosphatase Activity Assays/Reagents		Recombinant/Natural Proteins for FSTL4 (Follistatin-like 4/FSTL4)

	Browse OriGene Antibodies		OriGene shRNA RFP for FSTL4
	OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for FSTL4		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for FSTL4
	OriGene Protein Over-expression Lysate for FSTL4		Browse OriGene Fluorogenic Cell Assay Kits
	OriGene siRNA for FSTL4		Browse 3'-UTR reporter clones for miRNA target validation
	OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for FSTL4		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for FSTL4
	Browse OriGene GFP tagged cDNA clones in CMV expression vector		Browse OriGene MicroRNA Expression Plasmids
	Browse OriGene basic RS shRNAs		Browse OriGene validated miRNA SYBR primer pairs
	OriGene Purified Protein for FSTL4		OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
	OriGene Custom Antibody Services for FSTL4		OriGene Custom Protein Services for FSTL4
	OriGene Custom Immunoassay Development

	QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat FSTL4
	QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing FSTL4
	QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat FSTL4
	QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat FSTL4
	QIAGEN QuantiFast Probe-based Assays in human, mouse, rat FSTL4
	QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat FSTL4

	GenScript Custom Purified and Recombinant Proteins Services for FSTL4		GenScript cDNA clones with any tag delivered in your preferred vector for FSTL4
	GenScript Custom Assay Services for FSTL4		GenScript Custom Superior Antibodies Services for FSTL4
	GenScript Custom overexpressing Cell Line Services for FSTL4		CloneReady with Over 120,000 Genes
	Gene Synthesis: Any Gene in Any Vector		Vector-based siRNA and miRNA, Ready for Transfection
	Gene Mutant Library, Variants up to 10^11		Plasmid Preparation
	Custom Peptide Services

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	Regulatory tfbs in FSTL4 promoter
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	RT² qPCR Primer Assay in human, mouse, rat FSTL4
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	SABiosciences Custom PCR Arrays for FSTL4

Search Tocris compounds for FSTL4

	Browse Sino Biological Proteins and Antibodies
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Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

	Novus Tissue Slides
	FSTL4 antibodies
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	FSTL4 lysates

	Antibodies for FSTL4
	See all of Abcam's Antibodies, Kits and Proteins for FSTL4
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Browse ProSpec Recombinant Proteins

FSTL4 Proteins, Antibodies, CLIAs, and ELISAs

Search LifeMap BioReagents cell lines for FSTL4

	Gene Synthesis
	Protein Engineering
	Variant Library Synthesis
	Codon Optimization
	Protein Production and Purification

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FSTL4

	SwitchGear 3'UTR luciferase reporter plasmids for FSTL4
	SwitchGear Promoter luciferase reporter plasmids for FSTL4

Search ThermoFisher Antibodies for FSTL4

Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FSTL4

inGenious Targeting Laboratory - Customizable classic, inducible, and humanized mouse model solutions for FSTL4

Sirion Biotech Customized:

	stable knockdown cell line services for FSTL4
	inducible knockdown cell line services for FSTL4
	design and validation of potent shRNA sequences against FSTL4
	adenovirus for potent knockdown of FSTL4
	adenovirus for overexpression of FSTL4
	stable overexpressing cell line services for FSTL4
	inducible overexpressing cell line services for FSTL4

GeneCards Homepage - Last full update: 19 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 26 Apr 2013 , 13 May 2013

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Category			VWF (GIFTS: 73) von Willebrand factor
GIFtS Group

The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

The GeneCards Human Gene Database

Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

Hot genes Disease genes FSTL4 gene at Home site.

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FSTL4 Gene

follistatin-like 4

Aliases
for FSTL4 gene

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Proteins
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Protein Domains /
Families
for FSTL4 gene

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Pathways & Interactions
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Drugs & Compounds
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Transcripts
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Expression
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Orthologs
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Export list of displayed genes

FSTL4 Gene

follistatin-like 4

Aliasesfor FSTL4 gene

Summariesfor FSTL4 gene

Genomic Viewsfor FSTL4 gene

Proteinsfor FSTL4 gene

Protein Domains /Familiesfor FSTL4 gene

Functionfor FSTL4 gene

Pathways & Interactionsfor FSTL4 gene

Drugs & Compoundsfor FSTL4 gene

Transcriptsfor FSTL4 gene

Expression for FSTL4 gene

Orthologsfor FSTL4 gene

Paralogsfor FSTL4 gene

Genomic Variantsfor FSTL4 gene

Disorders / Diseasesfor FSTL4 gene

Publicationsfor FSTL4 gene

External Searches for FSTL4 gene

Genome Databases showing FSTL4 gene

Other Databases showing FSTL4 gene

Specialized Databases showing FSTL4 gene

Intellectual Propertyfor FSTL4 gene

Productsfor FSTL4 gene

View Random Gene

Aliases
for FSTL4 gene

Summaries
for FSTL4 gene

Genomic Views
for FSTL4 gene

Proteins
for FSTL4 gene

Protein Domains /
Families
for FSTL4 gene

Function
for FSTL4 gene

Pathways & Interactions
for FSTL4 gene

Drugs & Compounds
for FSTL4 gene

Transcripts
for FSTL4 gene

Expression
for FSTL4 gene

Orthologs
for FSTL4 gene

Paralogs
for FSTL4 gene

Genomic Variants
for FSTL4 gene

Disorders / Diseases
for FSTL4 gene

Publications
for FSTL4 gene

Intellectual Property
for FSTL4 gene

Products
for FSTL4 gene