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Aliases for FSIP2 Gene

Aliases for FSIP2 Gene

  • Fibrous Sheath Interacting Protein 2 2 3

External Ids for FSIP2 Gene

Previous GeneCards Identifiers for FSIP2 Gene

  • GC02P186813
  • GC02P186435
  • GC02P186318
  • GC02U901571
  • GC02P186603
  • GC02P178463

Summaries for FSIP2 Gene

GeneCards Summary for FSIP2 Gene

FSIP2 (Fibrous Sheath Interacting Protein 2) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FSIP2 Gene

Genomics for FSIP2 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for FSIP2 Gene

185,738,628 bp from pter
185,833,290 bp from pter
94,663 bases
Plus strand

Genomic View for FSIP2 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for FSIP2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for FSIP2 Gene

No data available for Regulatory Elements for FSIP2 Gene

Proteins for FSIP2 Gene

  • Protein details for FSIP2 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Fibrous sheath-interacting protein 2
    Protein Accession:
    Secondary Accessions:
    • Q53TL3
    • Q53TN5
    • Q5HYH2
    • Q6ZTZ5
    • Q6ZU14
    • Q6ZU21

    Protein attributes for FSIP2 Gene

    6907 amino acids
    Molecular mass:
    780607 Da
    Quaternary structure:
    • May interact with AKAP4.
    • Sequence=AAY14863.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305}; Sequence=AK126051; Type=Frameshift; Positions=6474; Evidence={ECO:0000305}; Sequence=CAI46017.1; Type=Frameshift; Positions=Several; Evidence={ECO:0000305}; Sequence=CAI46017.1; Type=Miscellaneous discrepancy; Note=Aberrant splicing.; Evidence={ECO:0000305};

    Alternative splice isoforms for FSIP2 Gene


neXtProt entry for FSIP2 Gene

Proteomics data for FSIP2 Gene at MOPED

Post-translational modifications for FSIP2 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for FSIP2 Gene

No data available for DME Specific Peptides for FSIP2 Gene

Domains for FSIP2 Gene

Protein Domains for FSIP2 Gene


Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with FSIP2: view

No data available for Gene Families and UniProtKB/Swiss-Prot for FSIP2 Gene

Function for FSIP2 Gene

Gene Ontology (GO) - Molecular Function for FSIP2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding --
genes like me logo Genes that share ontologies with FSIP2: view

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for FSIP2 Gene

Localization for FSIP2 Gene

Subcellular locations from

Jensen Localization Image for FSIP2 Gene COMPARTMENTS Subcellular localization image for FSIP2 gene
Compartment Confidence
cytoskeleton 1
cytosol 1
endoplasmic reticulum 1
extracellular 1
mitochondrion 1
nucleus 1
plasma membrane 1

Gene Ontology (GO) - Cellular Components for FSIP2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005739 mitochondrion --
genes like me logo Genes that share ontologies with FSIP2: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot for FSIP2 Gene

Pathways for FSIP2 Gene

SuperPathways for FSIP2 Gene

No Data Available

Interacting Proteins for FSIP2 Gene

STRING Interaction Network Preview (showing 2 interactants - click image to see details)
Selected Interacting proteins: ENSP00000344403 for FSIP2 Gene via STRING

Gene Ontology (GO) - Biological Process for FSIP2 Gene


No data available for Pathways by source for FSIP2 Gene

Transcripts for FSIP2 Gene

Unigene Clusters for FSIP2 Gene

Fibrous sheath interacting protein 2:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for FSIP2

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for FSIP2 Gene

No ASD Table

Relevant External Links for FSIP2 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for FSIP2 Gene

mRNA expression in normal human tissues for FSIP2 Gene

mRNA differential expression in normal tissues according to GTEx for FSIP2 Gene

This gene is overexpressed in Testis (17.2) and Colon - Transverse (9.8).

Protein differential expression in normal tissues for FSIP2 Gene

This gene is overexpressed in Breast (18.9), Plasma (9.8), and Liver (6.1).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for FSIP2 Gene

SOURCE GeneReport for Unigene cluster for FSIP2 Gene Hs.98025

genes like me logo Genes that share expressions with FSIP2: view

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA Expression by UniProt/SwissProt and Expression partners for FSIP2 Gene

Orthologs for FSIP2 Gene

This gene was present in the common ancestor of chordates.

Orthologs for FSIP2 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia FSIP2 35
  • 81.57 (n)
  • 69.26 (a)
FSIP2 36
  • 69 (a)
(Canis familiaris)
Mammalia FSIP2 35
  • 81.02 (n)
  • 69.25 (a)
FSIP2 36
  • 68 (a)
(Mus musculus)
Mammalia Fsip2 35
  • 75.26 (n)
  • 61.64 (a)
Fsip2 16
Fsip2 36
  • 59 (a)
(Pan troglodytes)
Mammalia FSIP2 35
  • 99.36 (n)
  • 98.67 (a)
FSIP2 36
  • 99 (a)
(Rattus norvegicus)
Mammalia Fsip2 35
  • 73.67 (n)
  • 60.59 (a)
(Monodelphis domestica)
Mammalia -- 36
  • 50 (a)
-- 36
  • 48 (a)
(Ornithorhynchus anatinus)
Mammalia FSIP2 36
  • 60 (a)
(Anolis carolinensis)
Reptilia FSIP2 36
  • 26 (a)
Species with no ortholog for FSIP2:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for FSIP2 Gene

Gene Tree for FSIP2 (if available)
Gene Tree for FSIP2 (if available)

Paralogs for FSIP2 Gene Pseudogenes for FSIP2 Gene

genes like me logo Genes that share paralogs with FSIP2: view

No data available for Paralogs for FSIP2 Gene

Variants for FSIP2 Gene

Sequence variations from dbSNP and Humsavar for FSIP2 Gene

SNP ID Clin Chr 02 pos Sequence Context AA Info Type MAF
rs767042 -- 185,824,832(-) GGCAT(A/G)ATCCT intron-variant
rs1468999 -- 185,833,149(-) CAAAG(C/T)TGAAG reference, missense
rs1544709 -- 185,742,792(-) CTCTC(A/T)TTTCC intron-variant
rs1544710 -- 185,742,768(-) GAATC(A/G)AAATA intron-variant
rs1862066 -- 185,807,185(-) CCTGA(C/T)GTTGG missense, reference

Structural Variations from Database of Genomic Variants (DGV) for FSIP2 Gene

Variant ID Type Subtype PubMed ID
nsv875545 CNV Loss 21882294
esv2721236 CNV Deletion 23290073

Relevant External Links for FSIP2 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for FSIP2 Gene

Disorders for FSIP2 Gene

(1) University of Copenhagen DISEASES for FSIP2 Gene

Relevant External Links for FSIP2

Human Genome Epidemiology (HuGE) Navigator
genes like me logo Genes that share disorders with FSIP2: view

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , Novoseek inferred disease relationships and Genatlas for FSIP2 Gene

Publications for FSIP2 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 2 3 4
  2. A germline-specific class of small RNAs binds mammalian Piwi proteins. (PMID: 16751776) Girard A. … Carmell M.A. (Nature 2006) 3
  3. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose J.E. … Uhl G.R. (Mol. Med. 2010) 3
  4. Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression. (PMID: 20877624) Hendrickson S.L. … O'Brien S.J. (PLoS ONE 2010) 3
  5. Identification of new mechanisms of cellular response to chemotherapy by tracking changes in post-translational modifications by ubiquitin and ubiquitin-like proteins. (PMID: 24654937) Bonacci T. … Soubeyran P. (J. Proteome Res. 2014) 3

Products for FSIP2 Gene

Sources for FSIP2 Gene

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