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Aliases for FSIP1 Gene

Aliases for FSIP1 Gene

  • Fibrous Sheath Interacting Protein 1 2 3
  • Fibrous Sheath-Interacting Protein 1 3
  • HSD10 3

External Ids for FSIP1 Gene

Previous GeneCards Identifiers for FSIP1 Gene

  • GC15M037609
  • GC15M037679
  • GC15M039892
  • GC15M016735

Summaries for FSIP1 Gene

GeneCards Summary for FSIP1 Gene

FSIP1 (Fibrous Sheath Interacting Protein 1) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FSIP1 Gene

Genomics for FSIP1 Gene

Regulatory Elements for FSIP1 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for FSIP1 Gene

39,594,171 bp from pter
39,782,838 bp from pter
188,668 bases
Minus strand

Genomic View for FSIP1 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for FSIP1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for FSIP1 Gene

Proteins for FSIP1 Gene

  • Protein details for FSIP1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Fibrous sheath-interacting protein 1
    Protein Accession:
    Secondary Accessions:
    • Q6X2C8
    • Q86Y89

    Protein attributes for FSIP1 Gene

    581 amino acids
    Molecular mass:
    66121 Da
    Quaternary structure:
    No Data Available

neXtProt entry for FSIP1 Gene

Proteomics data for FSIP1 Gene at MOPED

Post-translational modifications for FSIP1 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for FSIP1 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for FSIP1 Gene

Domains for FSIP1 Gene

Protein Domains for FSIP1 Gene


Suggested Antigen Peptide Sequences for FSIP1 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the FSIP1 family.
  • Belongs to the FSIP1 family.
genes like me logo Genes that share domains with FSIP1: view

No data available for Gene Families for FSIP1 Gene

Function for FSIP1 Gene

Gene Ontology (GO) - Molecular Function for FSIP1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding --
genes like me logo Genes that share ontologies with FSIP1: view

Phenotypes for FSIP1 Gene

genes like me logo Genes that share phenotypes with FSIP1: view

Animal Model Products

miRNA for FSIP1 Gene

miRTarBase miRNAs that target FSIP1

No data available for Molecular function , Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targeting and HOMER Transcription for FSIP1 Gene

Localization for FSIP1 Gene

Subcellular locations from

Jensen Localization Image for FSIP1 Gene COMPARTMENTS Subcellular localization image for FSIP1 gene
Compartment Confidence
cytosol 2
nucleus 2
endoplasmic reticulum 1
mitochondrion 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for FSIP1 Gene

Pathways for FSIP1 Gene

SuperPathways for FSIP1 Gene

No Data Available

Interacting Proteins for FSIP1 Gene

STRING Interaction Network Preview (showing 2 interactants - click image to see details)
Selected Interacting proteins: ENSP00000280236 Q8NA03-FSIP1_HUMAN for FSIP1 Gene via STRING I2D

Gene Ontology (GO) - Biological Process for FSIP1 Gene


No data available for Pathways by source for FSIP1 Gene

Compounds for FSIP1 Gene

(1) PharmGKB related drug/compound annotations for FSIP1 Gene

Drug/compound Annotation
aspirin CA
genes like me logo Genes that share compounds with FSIP1: view

Transcripts for FSIP1 Gene

mRNA/cDNA for FSIP1 Gene

(9) REFSEQ mRNAs :
(3) Additional mRNA sequences :
(14) Selected AceView cDNA sequences:
(3) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for FSIP1 Gene

Fibrous sheath interacting protein 1:
Representative Sequences:

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for FSIP1

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for FSIP1 Gene

No ASD Table

Relevant External Links for FSIP1 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for FSIP1 Gene

mRNA expression in normal human tissues for FSIP1 Gene

mRNA differential expression in normal tissues according to GTEx for FSIP1 Gene

This gene is overexpressed in Testis (10.1).

Protein differential expression in normal tissues for FSIP1 Gene

This gene is overexpressed in Brain (42.1) and Testis (24.3).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for FSIP1 Gene

SOURCE GeneReport for Unigene cluster for FSIP1 Gene Hs.129598

genes like me logo Genes that share expressions with FSIP1: view

Expression partners for FSIP1 Gene

* - Elite partner

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for FSIP1 Gene

Orthologs for FSIP1 Gene

This gene was present in the common ancestor of chordates.

Orthologs for FSIP1 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia FSIP1 35
  • 84.02 (n)
  • 74.83 (a)
FSIP1 36
  • 70 (a)
(Canis familiaris)
Mammalia FSIP1 35
  • 83.92 (n)
  • 75.71 (a)
FSIP1 36
  • 75 (a)
(Mus musculus)
Mammalia Fsip1 35
  • 74.87 (n)
  • 64.87 (a)
Fsip1 16
Fsip1 36
  • 59 (a)
(Pan troglodytes)
Mammalia FSIP1 35
  • 99.08 (n)
  • 97.93 (a)
FSIP1 36
  • 98 (a)
(Rattus norvegicus)
Mammalia Fsip1 35
  • 72.67 (n)
  • 63.2 (a)
(Monodelphis domestica)
Mammalia FSIP1 36
  • 38 (a)
(Ornithorhynchus anatinus)
Mammalia FSIP1 36
  • 47 (a)
(Gallus gallus)
Aves FSIP1 35
  • 57.39 (n)
  • 42.23 (a)
FSIP1 36
  • 35 (a)
(Anolis carolinensis)
Reptilia FSIP1 36
  • 33 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia fsip1 35
  • 50.97 (n)
  • 41.8 (a)
(Danio rerio)
Actinopterygii fsip1 35
  • 47.71 (n)
  • 38.98 (a)
Species with no ortholog for FSIP1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for FSIP1 Gene

Gene Tree for FSIP1 (if available)
Gene Tree for FSIP1 (if available)

Paralogs for FSIP1 Gene

No data available for Paralogs for FSIP1 Gene

Variants for FSIP1 Gene

Sequence variations from dbSNP and Humsavar for FSIP1 Gene

SNP ID Clin Chr 15 pos Sequence Context AA Info Type MAF
rs9719 -- 39,598,734(+) AGTTT(A/T)TTGTC intron-variant
rs596717 -- 39,752,397(-) atttc(A/C)ccatc intron-variant
rs612775 -- 39,751,083(-) ctaac(A/G)agttg intron-variant
rs628076 -- 39,749,966(-) ctaca(A/G)ctttt intron-variant
rs639230 -- 39,749,723(-) ctttc(C/T)gtttt intron-variant

Structural Variations from Database of Genomic Variants (DGV) for FSIP1 Gene

Variant ID Type Subtype PubMed ID
nsv904094 CNV Gain 21882294
nsv832977 CNV Gain 17160897
nsv1502 CNV Loss 18451855
nsv832978 CNV Gain 17160897
esv1286390 CNV Insertion 17803354
esv24232 CNV Loss 19812545
esv2749591 CNV Deletion 23290073
nsv832979 CNV Gain+Loss 17160897

Relevant External Links for FSIP1 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for FSIP1 Gene

Disorders for FSIP1 Gene

Relevant External Links for FSIP1

Genetic Association Database (GAD)
Human Genome Epidemiology (HuGE) Navigator

No disorders were found for FSIP1 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships and Genatlas for FSIP1 Gene

Publications for FSIP1 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 2 3 4
  2. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose J.E. … Uhl G.R. (Mol. Med. 2010) 3 48
  3. Positive association between aspirin-intolerant asthma and genetic polymorphisms of FSIP1: a case-case study. (PMID: 20513247) Kim J.Y. … Shin H.D. (BMC Pulm Med 2010) 3 48
  4. Interactions of pathological hallmark proteins: tubulin polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. (PMID: 21832049) OlA!h J. … OvA!di J. (J. Biol. Chem. 2011) 3
  5. Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population. (PMID: 23251661) Comuzzie A.G. … Butte N.F. (PLoS ONE 2012) 3

Products for FSIP1 Gene

Sources for FSIP1 Gene

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