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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

FSCN2 Gene

protein-coding   GIFtS: 53
GCID: GC17P079495

fascin homolog 2, actin-bundling protein, retinal (Strongylocentrotus...

(Previous names: fascin (Strongylocentrotus purpuratus) homolog 2 (actin-bundling...)
 Explore 16 diseases affiliated with
FSCN2 via
MalaCards
our new
 Human Malady Compendium 
Biological research products
for FSCN2    

Aliases
for FSCN2 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
Fascin Homolog 2, Actin-Bundling Protein, Retinal (Strongylocentrotus
Purpuratus)1 2
RFSN1 2 5
RP301 2 5
Fascin (Strongylocentrotus Purpuratus) Homolog 2 (Actin-Bundling Protein,
Retinal)1
Fascin-21
Retinal Fascin3

External Ids:    HGNC: 39601   Entrez Gene: 257942   Ensembl: ENSG000001867657   OMIM: 6076435   UniProtKB: O149263   

Export aliases for FSCN2 gene to outside databases

Previous GC identifers: GC17U990164 GC17M080035 GC17P080195 GC17P077110 GC17P074944


Summaries
for FSCN2 gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
Entrez Gene summary for FSCN2:
This gene encodes a member of the fascin protein family. Fascins crosslink actin into filamentous bundles within
dynamic cell extensions. This family member is proposed to play a role in photoreceptor disk morphogenesis. A mutation
in this gene results in one form of autosomal dominant retinitis pigmentosa and macular degeneration. Multiple
transcript variants encoding different isoforms have been found for this gene. (provided by RefSeq, Jul 2008)

UniProtKB/Swiss-Prot: FSCN2_HUMAN, O14926
Function: Acts as an actin bundling protein. May play a pivotal role in photoreceptor cell-specific events, such as
disk morphogenesis

Gene Wiki entry for FSCN2


Genomic Views
for FSCN2 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000017.10  NC_018928.1  NT_010783.15  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the FSCN2 gene promoter:
         p53   AP-4   Tal-1beta   E47   GATA-2   E2F   E2F-1   c-Myb   TGIF   Pax-4a   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: FSCN2 promoter sequence
   Search SABiosciences Chromatin IP Primers for FSCN2

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat FSCN2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 17q25   Ensembl cytogenetic band:  17q25.3   HGNC cytogenetic band: 17q25

FSCN2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
FSCN2 gene location

GeneLoc information about chromosome 17         GeneLoc Exon Structure

GeneLoc location for GC17P079495:  view genomic region     (about GC identifiers)

Start:
 79,495,417 bp from pter      End:
 79,504,156 bp from pter
Size:
 8,740 bases      Orientation:
 plus strand

Proteins
for FSCN2 gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: FSCN2_HUMAN, O14926 (See protein sequence)
Recommended Name: Fascin-2  
Size: 492 amino acids; 55057 Da
Subcellular location: Cytoplasm, cytoskeleton (By similarity). Cell projection, stereocilium (By similarity)
Secondary accessions: A0AVC4

Explore the universe of human proteins at neXtProt for FSCN2: NX_O14926

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_O14926

    • FSCN2 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins (2 alternative transcripts): 
    NP_001070650.1  NP_036550.1  

    ENSEMBL proteins: 
     ENSP00000388716   ENSP00000334665  

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    Uscn Proteins for FSCN2

    Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005737cytoplasm IEA--
    GO:0015629actin cytoskeleton ISS--
    GO:0032420stereocilium IEA--


    FSCN2 for ontologies           About GeneDecksing



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    Protein Domains /
    Families
    for FSCN2 gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    FSCN2 for domains           About GeneDecksing

    3 InterPro domains/families:
     IPR022768 Fascin-domain
     IPR024703 Fascin
     IPR008999 Actin_cross-linking

    Graphical View of Domain Structure for InterPro Entry O14926

    ProtoNet protein and cluster: O14926

    UniProtKB/Swiss-Prot: FSCN2_HUMAN, O14926
    Similarity: Belongs to the fascin family


    Function
    for FSCN2 gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    Function Summary:

         UniProtKB/Swiss-Prot: FSCN2_HUMAN, O14926
    Function: Acts as an actin bundling protein. May play a pivotal role in photoreceptor cell-specific events, such as
    disk morphogenesis

    miRNA
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    Gene Editing
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    Clone
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    In Situ Assay
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    Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003779actin binding ISS--
    GO:0030674protein binding, bridging IEA--
    GO:0051015actin filament binding ISS--


    FSCN2 for ontologies           About GeneDecksing


    Animal Models:
         Mouse knock-outs for FSCN2: Fscn2tm1Sykk Fscn2tm2Sykk
         3 MGI mutant phenotypes (inferred from 3 alleles) (MGI details for Fscn2):
     hearing/vestibular/ear  nervous system  vision/eye 

    FSCN2 for phenotypes           About GeneDecksing


    Pathways & Interactions
    for FSCN2 gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section



    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for FSCN2

    Gene Ontology (GO): 5 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007601visual perception TAS10783262
    GO:0009653anatomical structure morphogenesis TAS10783262
    GO:0030036actin cytoskeleton organization ISS--
    GO:0042462eye photoreceptor cell development ----
    GO:0051017actin filament bundle assembly TAS10783262


    FSCN2 for ontologies           About GeneDecksing



    Drugs & Compounds
    for FSCN2 gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for FSCN2
    Search CenterWatch for drugs/clinical trials and news about FSCN2 

    Transcripts
    for FSCN2 gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for FSCN2 gene (2 alternative transcripts): 
    NM_001077182.2  NM_012418.3  

    Unigene Cluster for FSCN2:

    Fascin homolog 2, actin-bundling protein, retinal (Strongylocentrotus purpuratus)
    Hs.118555  [show with all ESTs]
    Unigene Representative Sequence: NM_001077182
    3 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000417245(uc010wuo.2 uc010wup.2) ENST00000334850 ENST00000527221


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    Inhib. RNA
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    Clone
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    Additional cDNA sequence: 

    AF030165.1 BC126295.1 BC130330.1 DQ426873.1 

    2 DOTS entries:

    DT.443550  DT.100741139 

    17 AceView cDNA sequences:

    BM929819 BM932109 BM709287 AI189621 AF030165 NM_012418 AA018553 BU732435 
    AA046412 BQ185852 AA017631 BQ186352 AA058860 AA046878 AA059324 AA018572 
    AI703219 

    GeneLoc Exon Structure

    2 Alternative Splicing Database (ASD) splice patterns (SP) for FSCN2    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3a · 3b
    SP1:                              
    SP2:                              


    ECgene alternative splicing isoforms for FSCN2

    Expression
    for FSCN2 gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    FSCN2 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: TTTGAGATGG

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)
    About this image

    FSCN2 expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table
    1 LifeMap In Vivo Development Anatomical Compartment/Cell 
    Tissue Anatomical Compartment CellCategory (developmental path)
    EyeOuter Nuclear LayerMature Rod CellsPhotoreceptors, Retina
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization
    Stem Cell Differentiation: 1 LifeMap Cell 
    NameCategory
    Posterior foregut-like cells (A scalable, suspensi...)

    See FSCN2 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for FSCN2

    SOURCE GeneReport for Unigene cluster: Hs.118555

    UniProtKB/Swiss-Prot: FSCN2_HUMAN, O14926
    Tissue specificity: Localized specifically in the outer and inner segments of the photoreceptor cells in the retina

        SABiosciences Expression via Pathway-Focused PCR Array including FSCN2: 
              Cytoskeleton Regulators in human mouse rat

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    In Situ
    Assay Products:     
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    Orthologs
    for FSCN2 gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of animals.

    Orthologs for FSCN2 gene from 6/17 species (see all 17)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    mouse
    (Mus musculus)    		 Mammalia Fscn21 , 5 fascin homolog 2, actin-bundling protein, retinal (Strongylocentrotus more1, 5 85.84(n)1
    90.85(a)1    		   11 (84.08 cM)5
    2380211  NM_172802.41  NP_766390.21 
     1203615345 
    chicken
    (Gallus gallus)    		 Aves FSCN21 fascin homolog 2, actin-bundling protein, retinal (Strongylocentrotus more 76.51(n)
    70.47(a)    		   429198  NM_001177738.1  NP_001171209.1 
    lizard
    (Anolis carolinensis)    		 Reptilia FSCN26
    		 --
    		 70(a)
    		 1 ↔ 1
    		 2(98637253-98659158)
    African clawed frog
    (Xenopus laevis)    		 Amphibia Xl.263332 Xenopus laevis transcribed sequence with weak similarity more 75.03(n)    CD328490.1 
    zebrafish
    (Danio rerio)    		 Actinopterygii zgc732722 hypothetical protein MGC73272 74.98(n)   393743  BC059601.1 
    fruit fly
    (Drosophila melanogaster)    		 Insecta sn3 actin filament organization actin binding 38(a)     --


    ENSEMBL Gene Tree for FSCN2 (if available)
    TreeFam Gene Tree for FSCN2 (if available) 

    Paralogs
    for FSCN2 gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for FSCN2 gene
    FSCN32  FSCN12  
    1 SIMAP similar gene for FSCN2 using alignment to 2 protein entries:     FSCN2_HUMAN (see all proteins):
    FSCN1

    FSCN2 for paralogs           About GeneDecksing



    Genomic Variants
    for FSCN2 gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/246 NCBI SNPs in FSCN2 are shown (see all 246)     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 17 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs1378539001,2
    		C,untested79495606(+) GCCTCA/GTCAAC 4 I V mis10--------
    rs1512024181,2
    		--79493422(+) GAGGCC/TGCGGC 2 -- us2k10--------
    rs1403892911,2
    		--79493424(+) GGCCGC/TGGCGG 2 -- us2k10--------
    rs749993271,2
    		C--79493427(+) CGCGGC/TGGGCA 2 -- us2k10--------
    rs1911157561,2
    		--79493455(+) AGTTCA/GAGACC 2 -- us2k10--------
    rs1823574541,2
    		--79493581(+) GAGCTC/TGAAGG 2 -- us2k10--------
    rs72211901,2
    		C,F,A,H,--79493705(-) GCTAGG/AGTGCT 2 -- us2k126Minor allele frequency- A:0.27NS EA NA WA CSA 2562
    rs1890866391,2
    		--79493877(+) TCGCAC/TACAGT 2 -- us2k10--------
    rs1931508061,2
    		--79493906(+) TGTGAA/CTCATA 2 -- us2k10--------
    rs1163961961,2
    		F,--79493917(+) GAGGCG/AGATGA 2 -- us2k11Minor allele frequency- A:0.03WA 118

    HapMap Linkage Disequilibrium report for FSCN2 (79495417 - 79504156 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 4 variations for FSCN2
         4 CNVs: 73071 5040 35515 5039
    Human Gene Mutation Database (HGMD): FSCN2

    Locus Specific Mutation Databases (LSDB): FSCN2

    SABiosciences Cancer Mutation PCR Assays
    QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing FSCN2
    DNA2.0 Custom Variant and Variant Library Synthesis for FSCN2

    Disorders / Diseases
    for FSCN2 gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    FSCN2 for disorders           About GeneDecksing

    OMIM gene information: 607643   
    OMIM disorders: 607921  
    UniProtKB/Swiss-Prot: FSCN2_HUMAN, O14926
  • Defects in FSCN2 are the cause of retinitis pigmentosa type 30 (RP30) [MIM:607921]. RP leads to degeneration
    • of retinal photoreceptor cells. Patients typically have night vision blindness and loss of midperipheral visual field.
    As their condition progresses, they lose their far peripheral visual field and eventually central vision as well. RP30
    inheritance is autosomal dominant

    16 diseases for FSCN2:    About MalaCards
    retinitis pigmentosa    retinitis    macular degeneration    retinitis pigmentosa 30
    dendritic cell sarcoma    retinal degeneration    esophageal squamous cell carcinoma    squamous cell carcinoma
    ehrlichiosis    histiocytosis    oral cancer    esophagitis
    colon cancer    blindness    sarcoma    carcinoma

    3 diseases from the University of Copenhagen DISEASES database for FSCN2:
    Histiocytosis     Carcinoma     Retinitis pigmentosa

    3 Novoseek disease relationships for FSCN2 gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    retinitis pigmentosa 81 8 14609921 (2), 11527955 (2), 16280978 (2), 16043865 (1) (see all 5)
    retinal degeneration 62.5 3 17251446 (2)
    retinopathy 43.7 1 16043865 (1)

    Genetic Association Database (GAD): FSCN2
    Human Genome Epidemiology (HuGE) Navigator: FSCN2 (3 documents)

    Export disorders for FSCN2 gene to outside databases

    Publications
    for FSCN2 gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for FSCN2 gene, integrated from 9 sources (see all 20):
    (articles sorted by number of sources associating them with FSCN2)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. Refinement of the RP17 locus for autosomal dominant retinitis pigmentosa, construction of a YAC contig and investigation of the candidate gene retinal fascin. (PubMed id 10234509)1, 2, 3 Bardien-Kruger S.... Ramesar R.S. (1999)
    2. Characterization of human retinal fascin gene (FSCN2) at 17q25: close physical linkage of fascin and cytoplasmic actin genes. (PubMed id 10783262)1, 2, 9 Tubb B.E.... Bryan J. (2000)
    3. Autosomal dominant macular degeneration associated with 208delG mutation in the FSCN2 gene. (PubMed id 14609921)1, 4, 9 Wada Y....Tamai M. (2003)
    4. Mutation of human retinal fascin gene (FSCN2) causes autosomal dominant retinitis pigmentosa. (PubMed id 11527955)1, 2, 9 Wada Y.... Tamai M. (2001)
    5. Sequence variations in the retinal fascin FSCN2 gene in a Spanish population with autosomal dominant retinitis pigmentosa or macular degeneration. (PubMed id 16280978)1, 4, 9 Gamundi M.J....Carballo M. (2005)
    6. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    7. [Molecular genetic analysis for Japanese patients with autosomal dominant retinitis pigmentosa] (PubMed id 14661542)1, 4 Wada Y. and Tamai M. (2003)
    8. Retinal fascin: functional nature, subcellular distribution, and chromosomal localization. (PubMed id 10892848)1, 2 Saishin Y.... Shimada S. (2000)
    9. The 208delG mutation in FSCN2 does not associate with retinal degeneration in Chinese individuals. (PubMed id 17251446)1, 9 Zhang Q....Guo X. (2007)
    10. The filopodium: a stable structure with highly regula ted repetitive cycles of elongation and persistence depending on the actin cros s-linker fascin. (PubMed id 21975552)1 SchAofer C....Hoffmann B. (2011)

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    Genome Databases showing FSCN2 gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 25794 HGNC: 3960 AceView: FSCN2 Ensembl:ENSG00000186765 euGenes: HUgn25794
    ECgene: FSCN2 H-InvDB: FSCN2

    Other Databases showing FSCN2 gene

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    Specialized Databases showing FSCN2 gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for FSCN2 Pharmacogenomics, SNPs, Pathways
    Mutations of the FSCN2 genehttp://www.retina-international.org/files/sci-news/fscn2mut.htm

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