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Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

FRY Gene

protein-coding GIFtS: 51
GCID: GC13P032605

furry homolog (Drosophila)

(Previous name: chromosome 13 open reading frame 14 )
(Previous symbol: C13orf14)

Explore 5 diseases affiliated with
FRY via

MalaCards

our new
Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

Aliases
Furry Homolog (Drosophila)¹ ²		Chromosome 13 Open Reading Frame 14¹
C13orf14¹ ² ³		214K23.2²
13CDNA73¹ ²		WUGSC:H_2G3A.1²
CG003¹ ²		BA207N4.2¹
BA37E23.1¹		Protein Furry Homolog²

External Ids:	HGNC: 20367¹	Entrez Gene: 10129²	Ensembl: ENSG00000073910⁷	OMIM: 614818⁵	UniProtKB: Q5TBA9³

Export aliases for FRY gene to outside databases

Previous GC identifers: GC13P031504 GC13P013416

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

UniProtKB/Swiss-Prot: FRY_HUMAN, Q5TBA9

Function: Plays a crucial role in the structural integrity of mitotic centrosomes and in the maintenance of spindle

bipolarity by promoting PLK1 activity at the spindle poles in early mitosis. May function as a scaffold promoting the

interaction between AURKA and PLK1, thereby enhancing AURKA-mediated PLK1 phosphorylation

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000013.10 NC_018924.1 NT_024524.14

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the FRY gene promoter:
FOXO3 Nkx5-1 RORalpha2 GATA-1 Evi-1 FOXO3b AREB6 FOXJ2 (long isoform) FOXO3a FOXJ2
Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: FRY promoter sequence

Search SABiosciences Chromatin IP Primers for FRY

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat FRY

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 13q13.1 Ensembl cytogenetic band: 13q13.1 HGNC cytogenetic band: 13q13.1

FRY Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
FRY gene location

GeneLoc information about chromosome 13 GeneLoc Exon Structure

GeneLoc location for GC13P032605: view genomic region (about GC identifiers)

Start:	32,605,437 bp from pter	End:	32,870,794 bp from pter
Size:	265,358 bases	Orientation:	plus strand

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: FRY_HUMAN, Q5TBA9 (See protein sequence)

Recommended Name: Protein furry homolog

Size: 3013 amino acids; 338875 Da

Subunit: When phosphorylated by CDK1, interacts with PLK1; this interaction occurs in mitotic cells, but not in

interphase cells, and leads to further phosphorylation by PLK1. Interacts with AURKA

Subcellular location: Cytoplasm. Cytoplasm, cytoskeleton, centrosome. Cytoplasm, cytoskeleton, spindle pole.

Note=Distributed diffusely throughout the cytoplasm in interphase. Localizes to the separating centrosomes in

prophase, to the spindle poles and spindle microtubules in prometaphase to metaphase, to spindle microtubules in

anaphase and to the distal sections of the midbody in cytokinesis. Colocalizes with PLK1 to separating centrosomes and

spindle poles from prophase to metaphase in mitosis, but not in other stages of the cell cycle

Sequence caution: Sequence=CAB42442.1; Type=Frameshift; Positions=1340, 1378;

Secondary accessions: Q9Y3N6

Explore the universe of human proteins at neXtProt for FRY: NX_Q5TBA9

Post-translational modifications:

Phosphorylated by AURKA, CDK1 and PLK1¹

View modification sites using PhosphoSitePlus²

View neXtProt modification sites for NX_Q5TBA9

FRY Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins: NP_075463.2

ENSEMBL proteins:

ENSP00000369600 ENSP00000398010 ENSP00000434694 ENSP00000369565 ENSP00000445043

Human Recombinant Protein Products:

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	Browse Sino Biological Recombinant Proteins
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	Uscn Proteins for FRY

Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0000922	spindle pole	IEA	--
GO:0005737	cytoplasm	IEA	--
GO:0005815	microtubule organizing center	IEA	--
GO:0016021	integral to membrane	--	--

FRY for ontologies About GeneDecksing

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	Uscn Antibodies for FRY
	Search ThermoFisher Antibodies for FRY

Assay Products for FRY:

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	Uscn ELISAs and CLIAs for FRY

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

FRY for domains About GeneDecksing

2 InterPro domains/families:

IPR025614 Cell_morpho_N

IPR025481 Cell_Morphogen_C

Graphical View of Domain Structure for InterPro Entry Q5TBA9

ProtoNet protein and cluster: Q5TBA9

1 Blocks protein family: IPB006203 GHMP kinase

UniProtKB/Swiss-Prot: FRY_HUMAN, Q5TBA9

Similarity: Belongs to the furry protein family

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

Function Summary:

UniProtKB/Swiss-Prot: FRY_HUMAN, Q5TBA9

Function: Plays a crucial role in the structural integrity of mitotic centrosomes and in the maintenance of spindle

bipolarity by promoting PLK1 activity at the spindle poles in early mitosis. May function as a scaffold promoting the

interaction between AURKA and PLK1, thereby enhancing AURKA-mediated PLK1 phosphorylation

miRNA Products:		OriGene 3'-UTR Clone: FRY Browse MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat FRY
		8/21 QIAGEN miScript miRNA Assays for microRNAs that regulate FRY (see all 21):
		hsa-miR-137 hsa-miR-15a hsa-miR-503 hsa-miR-25 hsa-miR-628-3p hsa-miR-424 hsa-miR-9 hsa-miR-4325

		SwitchGear 3'UTR luciferase reporter plasmid: FRY 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for FRY OriGene shRNA RFP: FRY OriGene siRNA: FRY
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Gene Editing
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		GenScript: all cDNA clones in your preferred vector: FRY (NM_023037)
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Cell Line Products:		GenScript Custom overexpressing Cell Line Services for FRY
		Search LifeMap BioReagents cell lines for FRY

In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FRY

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Interactions:

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for FRY

STRING Interaction Network Preview (showing 2 interactants - click image to see more details)

5/9 Interacting proteins for FRY (Q5TBA9^{2, 3} ENSP00000369600⁴) via UniProtKB, MINT, STRING, and/or I2D (see all 9)

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
YWHAG	P61981²^,³, ENSP00000306330⁴	MINT-50897 I2D: score=1 STRING: ENSP00000306330
UBC	P0CG48³, ENSP00000344818⁴	I2D: score=1 STRING: ENSP00000344818
AKT3	Q9Y243³	I2D: score=4
ARHGAP1	Q07960³	I2D: score=4
MCM5	P33992³	I2D: score=4

About this table

Gene Ontology (GO): 2 biological process terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0006351	transcription, DNA-dependent	--	--
GO:0006355	regulation of transcription, DNA-dependent	--	--

FRY for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for FRY
Search CenterWatch for drugs/clinical trials and news about FRY

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for FRY gene:

NM_023037.2

Unigene Cluster for FRY:

Furry homolog (Drosophila)

Hs.507669 [show with all ESTs]

Unigene Representative Sequence: NM_023037

6 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000380250(uc001utx.3 uc010tdw.2 uc001utz.3 uc010tdx.2)

ENST00000463566 ENST00000436046 ENST00000477712 ENST00000380217 ENST00000542859

miRNA Products:		OriGene 3'-UTR Clone: FRY Browse OriGene MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat FRY
		8/21 QIAGEN miScript miRNA Assays for microRNAs that regulate FRY (see all 21):
		hsa-miR-137 hsa-miR-15a hsa-miR-503 hsa-miR-25 hsa-miR-628-3p hsa-miR-424 hsa-miR-9 hsa-miR-4325

		SwitchGear 3'UTR luciferase reporter plasmid: FRY 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for FRY OriGene shRNA RFP: FRY OriGene siRNA: FRY
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat FRY

Clone Products:		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for FRY (see all 2) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for FRY OriGene custom cloning services � gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector: FRY (NM_023037)
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Additional cDNA sequence:

AK091422.1 AK298021.1 AL049784.1 BX648226.1 U50526.1 U50534.1 U57961.1

13 DOTS entries:

DT.455706 DT.100022238 DT.100810409 DT.70104802 DT.101974982 DT.91739417 DT.91694870 DT.97840666

DT.421693 DT.91739396 DT.95164829 DT.99968845 DT.454125

24/134 AceView cDNA sequences (see all 134):

CR621863 CB528947 BE531155 BM721728 BI493200 AK091422 AA740292 BM677315

BM707606 BU733162 NM_023037 CA952510 BX494316 AA350131 BG210974 AL049784

AA804739 BX441369 AI221603 D79325 BX641976 BQ015530 AI801267 BI766462

GeneLoc Exon Structure

5/7 Alternative Splicing Database (ASD) splice patterns (SP) for FRY (see all 7) About this scheme

ExUns:	1a	·	1b	^	2	^	3	^	4	^	5	^	6	^	7	^	8	^	9	^	10	^	11	^	12	^	13	^	14	^	15	^	16	^	17	^	18	^	19	^	20	^	21	^	22	^	23	^	24	^	25	^
SP1:					-
SP2:
SP3:
SP4:
SP5:

ExUns:	26	^	27	^	28	^	29	^	30	^	31	^	32a	·	32b	^	33	^	34	^	35	^	36	^	37	^	38	^	39	^	40	^	41	^	42	^	43	^	44	^	45	^	46	^	47	^	48	^	49	^	50	^
SP1:
SP2:
SP3:
SP4:
SP5:

ExUns:	51	^	52a	·	52b	·	52c	^	53	^	54	^	55a	·	55b	^	56a	·	56b	·	56c	^	57	^	58	^	59a	·	59b	^	60	^	61	^	62	^	63a	·	63b
SP1:			-		-										-														-		-
SP2:
SP3:															-
SP4:
SP5:

ECgene alternative splicing isoforms for FRY

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

FRY expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TGAACTTGTT

About this image

FRY expression in embryonic tissues and stem cells

Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine About this table

3 LifeMap In Vivo Development Anatomical Compartments/Cells

Tissue

Anatomical Compartment

Cell

Category (developmental path)

Bone

Zeugopod Epiphyseal End

Chondrocytes

Bone, Cartilage

Brain

Neural Tube

Expression:

Positive

Negative

Selective marker

Experimental details:

Curated

Microarrays

In-situ hybridization

See FRY Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for FRY

SOURCE GeneReport for Unigene cluster: Hs.507669

SABiosciences Custom PCR Arrays for FRY

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In Situ
Assay Products:

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(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of eukaryotes.

Orthologs for FRY gene from 8/26 species (see all 26) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
chicken (Gallus gallus)	Aves	FRY¹	furry homolog (Drosophila)	82.26(n) 93.75(a)		418915 XM_003640579.1 XP_003640627.1
lizard (Anolis carolinensis)	Reptilia	FRY⁶	--	92(a)	1 ↔ 1	3(183769238-183910617)
African clawed frog (Xenopus laevis)	Amphibia	Xl.8693²	Xenopus laevis transcribed sequence with moderate similarity to protein refNP_075463.1 (H.sapiens) hypothetical protein CG003 [Homo sapiens] less	79.46(n)		BJ070503.1
zebrafish (Danio rerio)	Actinopterygii	fryb¹	furry homolog b (Drosophila)	71.52(n) 79.03(a)		792949 XM_001332213.4 XP_001332249.2
fruit fly (Drosophila melanogaster)	Insecta	fry⁶	furry	32(a)	1 → many	3L(9624934-9672203)
worm (Caenorhabditis elegans)	Secernentea	sax-2⁶	Sensory AXon guidance family member (sax-2)	28(a)	1 → many	III(5109662-5130636)
thale cress (Arabidopsis thaliana)	eudicotyledons	AT5G15680⁶	armadillo/beta-catenin-like repeat-containing prot...	19(a)	1 → many	5(5100984-5111029)
rice (Oryza sativa)	Liliopsida	--	expressed protein	20(a)	1 → many	2(35712181-35724695)

ENSEMBL Gene Tree for FRY (if available)
TreeFam Gene Tree for FRY (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for FRY gene

FRYL²

5 SIMAP similar genes for FRY using alignment to 6 protein entries: FRY_HUMAN (see all proteins):

DKFZp686K08123 214K23.2 FRYL DKFZp781A0295 WUGSC

FRY for paralogs About GeneDecksing

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 13 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs2021653^1,2	C,F,A,	--	13415438(+)	`CTAAAA/CTTTAA`	1	--	int¹		6		NA WA	264
rs79868944^1,2		--	13415482(+)	`AGCCCC/GTTTCA`	1	--	int¹		2		CSA WA	120
rs74044314^1,2	C,	--	13416002(+)	`ATCTTA/CGGGCC`	1	--	int¹		2		WA	120
rs78679829^1,2	F,	--	13416140(+)	`TTTGTG/ATGTTG`	1	--	int¹		1		WA	118
rs77491090^1,2		--	13416221(+)	`TTTAGA/GCAACA`	1	--	int¹		1		WA	118
rs116519684^1,2	C,F,	--	13416704(+)	`GAAAAA/GGNNNN`	1	--	int¹		1		WA	118
rs374620^1,2	C,A	--	13417699(+)	`TTTCTC/TTTTCT`	1	--	us2k¹ trp³		0	--	--	--	--
rs77392398^1,2		--	13417725(+)	`TTTTTT/CTTTCT`	1	--	us2k¹		1		CSA	1
rs9533201^1,2	F,H,	--	13418254(+)	`ATTAGG/CATAGC`	1	--	us2k¹		6		NS EA WA NA	632
rs76093191^1,2		--	13418591(+)	`TAGTGA/TTTAAT`	1	--	us2k¹		0	--	--	--	--

HapMap Linkage Disequilibrium report for FRY (32605437 - 32855437 bp, first 250kb of FRY)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 4 variations for FRY
3 CNVs: 49199 10415 86772
1 Indel: 76314
Human Gene Mutation Database (HGMD): FRY

SABiosciences Cancer Mutation PCR Assays

QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing FRY

DNA2.0 Custom Variant and Variant Library Synthesis for FRY

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

FRY for disorders           About GeneDecksing

OMIM gene information: 614818    OMIM disorders: --

5 diseases for FRY:    About MalaCards

glottis carcinoma diphyllobothriasis azoospermia neuronitis

carcinoma

1 disease from the University of Copenhagen DISEASES database for FRY:

Diphyllobothriasis

Human Genome Epidemiology (HuGE) Navigator: FRY (15 documents)

Export disorders for FRY gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
About This Section

PubMed articles for FRY gene, integrated from 9 sources (see all 13):
(articles sorted by number of sources associating them with FRY)

Utopia: connect your pdf to the dynamic
world of online information

Furry protein promotes Aurora A-mediated polo-like kinase 1 activation. (PubMed id 22753416)^{1, 2} Ikeda M.... Mizuno K. (2012)
The DNA sequence and analysis of human chromosome 13. (PubMed id 15057823)^{1, 2} Dunham A.... Ross M.T. (2004)
Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)^{1, 3} Ota T.... Sugano S. (2004)
Generation of an integrated transcription map of the BRCA2 region on chromosome 13q12-q13. (PubMed id 8812419)^{1, 3} Couch F.J.... Simard J. (1996)
Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)¹ Kim W....Gygi S.P. (2011)
Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)¹ Rose J.E....Uhl G.R. (2010)
MST2- and Furry-mediated activation of NDR1 kinase is critical for precise alignment of mitotic chromosomes. (PubMed id 19327996)¹ Chiba S....Mizuno K. (2009)
Large-scale proteomics analysis of the human kinome. (PubMed id 19369195)² Oppermann F.S.... Daub H. (2009)
Association between genetic variants in VEGF, ERCC3 a nd occupational benzene haematotoxicity. (PubMed id 19773279)¹ Hosgood H.D....Lan Q. (2009)
Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions. (PubMed id 19690332)² Mayya V.... Han D.K. (2009)

(in PubMed, OMIM, and NCBI Bookshelf)
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		AND	OR
Aliases
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(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 10129	HGNC: 20367	AceView: 13CDNA73	Ensembl:ENSG00000073910	euGenes: HUgn10129
ECgene: FRY	H-InvDB: FRY

(According to HUGE)
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(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
PharmGKB entry for FRY	Pharmacogenomics, SNPs, Pathways

Intellectual Property for FRY gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

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Patent Information for FRY gene:
Search GeneIP for patents involving FRY

GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search

(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences),
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GeneCards Homepage - Last full update: 19 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 26 Apr 2013

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furry homolog (Drosophila)

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FRY Gene

furry homolog (Drosophila)

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