Aliases for FRRS1 Gene
External Ids for FRRS1 Gene
Previous HGNC Symbols for FRRS1 Gene
Previous GeneCards Identifiers for FRRS1 Gene
Members of the cytochrome b561 (CYB561; MIM 600019) family, including FRRS1, reduce ferric to ferrous iron before its transport from the endosome to the cytoplasm (Vargas et al., 2003 [PubMed 14499595]).[supplied by OMIM, Mar 2008]
GeneCards Summary for FRRS1 Gene
FRRS1 (Ferric Chelate Reductase 1) is a Protein Coding gene. Diseases associated with FRRS1 include Multidrug-Resistant Tuberculosis. Gene Ontology (GO) annotations related to this gene include ferric-chelate reductase activity. An important paralog of this gene is FRRS1L.
UniProtKB/Swiss-Prot for FRRS1 Gene
Ferric-chelate reductases reduce Fe(3+) to Fe(2+) before its transport from the endosome to the cytoplasm.