Aliases for FRMPD4 Gene
External Ids for FRMPD4 Gene
Previous HGNC Symbols for FRMPD4 Gene
Previous GeneCards Identifiers for FRMPD4 Gene
This gene encodes a multi-domain (WW, PDZ, FERM) containing protein. Through its interaction with other proteins (such as PSD-95), it functions as a positive regulator of dendritic spine morphogenesis and density, and is required for the maintenance of excitatory synaptic transmission. [provided by RefSeq, Jan 2010]
GeneCards Summary for FRMPD4 Gene
FRMPD4 (FERM And PDZ Domain Containing 4) is a Protein Coding gene. Diseases associated with FRMPD4 include Mental Retardation, X-Linked 104 and X-Linked Non-Specific Intellectual Disability. GO annotations related to this gene include phosphatidylinositol-4,5-bisphosphate binding. An important paralog of this gene is FRMPD3.
UniProtKB/Swiss-Prot for FRMPD4 Gene
Positive regulator of dendritic spine morphogenesis and density. Required for the maintenance of excitatory synaptic transmission. Binds phosphatidylinositol 4,5-bisphosphate.