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Aliases for FRMPD3 Gene

Aliases for FRMPD3 Gene

  • FERM And PDZ Domain Containing 3 2 3
  • FERM And PDZ Domain-Containing Protein 3 3
  • RP5-1070B1.1 3
  • KIAA1817 4
  • EC 6.1.1 63
  • EC 3.6.1 63

External Ids for FRMPD3 Gene

Previous GeneCards Identifiers for FRMPD3 Gene

  • GC0XP106652
  • GC0XP106765

Summaries for FRMPD3 Gene

GeneCards Summary for FRMPD3 Gene

FRMPD3 (FERM And PDZ Domain Containing 3) is a Protein Coding gene. An important paralog of this gene is FRMPD4.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FRMPD3 Gene

Genomics for FRMPD3 Gene

Regulatory Elements for FRMPD3 Gene

Genomic Location for FRMPD3 Gene

107,522,450 bp from pter
107,605,251 bp from pter
82,802 bases
Plus strand

Genomic View for FRMPD3 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for FRMPD3 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for FRMPD3 Gene

Proteins for FRMPD3 Gene

  • Protein details for FRMPD3 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    FERM and PDZ domain-containing protein 3
    Protein Accession:
    Secondary Accessions:
    • Q96JK8

    Protein attributes for FRMPD3 Gene

    1810 amino acids
    Molecular mass:
    199209 Da
    Quaternary structure:
    No Data Available
    • Sequence=CAI42175.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305}; Sequence=CAI42749.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};

neXtProt entry for FRMPD3 Gene

Proteomics data for FRMPD3 Gene at MOPED

Selected DME Specific Peptides for FRMPD3 Gene

Post-translational modifications for FRMPD3 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for FRMPD3 Gene

ENSEMBL proteins:
REFSEQ proteins:

Domains for FRMPD3 Gene

Protein Domains for FRMPD3 Gene

Suggested Antigen Peptide Sequences for FRMPD3 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Q5JV73
  • Contains 1 FERM domain.
  • Contains 1 PDZ (DHR) domain.
genes like me logo Genes that share domains with FRMPD3: view

No data available for Gene Families for FRMPD3 Gene

Function for FRMPD3 Gene

Enzyme Numbers (IUBMB) for FRMPD3 Gene

Gene Ontology (GO) - Molecular Function for FRMPD3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding --
genes like me logo Genes that share ontologies with FRMPD3: view

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for FRMPD3

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for FRMPD3 Gene

Localization for FRMPD3 Gene

Subcellular locations from

Jensen Localization Image for FRMPD3 Gene COMPARTMENTS Subcellular localization image for FRMPD3 gene
Compartment Confidence
nucleus 3
cytoskeleton 2
cytosol 2
mitochondrion 1

Gene Ontology (GO) - Cellular Components for FRMPD3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005856 cytoskeleton IEA --
genes like me logo Genes that share ontologies with FRMPD3: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot for FRMPD3 Gene

Pathways for FRMPD3 Gene

SuperPathways for FRMPD3 Gene

No Data Available

Interacting Proteins for FRMPD3 Gene

STRING Interaction Network Preview (showing 3 interactants - click image to see details)
Selected Interacting proteins: ENSP00000276185 for FRMPD3 Gene via STRING

Gene Ontology (GO) - Biological Process for FRMPD3 Gene


No data available for Pathways by source for FRMPD3 Gene

Transcripts for FRMPD3 Gene

mRNA/cDNA for FRMPD3 Gene

(5) REFSEQ mRNAs :
(1) Additional mRNA sequences :
(1) Selected AceView cDNA sequences:
(3) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for FRMPD3 Gene

FERM and PDZ domain containing 3:
Representative Sequences:

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for FRMPD3

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for FRMPD3 Gene

No ASD Table

Relevant External Links for FRMPD3 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for FRMPD3 Gene

mRNA expression in normal human tissues for FRMPD3 Gene

mRNA differential expression in normal tissues according to GTEx for FRMPD3 Gene

This gene is overexpressed in Brain - Cerebellum (6.6), Brain - Cerebellar Hemisphere (6.2), Brain - Hypothalamus (4.6), and Thyroid (4.1).

Protein differential expression in normal tissues for FRMPD3 Gene

This gene is overexpressed in CD4 Tcells (34.8), Plasma (13.1), and Pancreatic juice (10.9).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for FRMPD3 Gene

SOURCE GeneReport for Unigene cluster for FRMPD3 Gene Hs.496546

genes like me logo Genes that share expressions with FRMPD3: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA Expression by UniProt/SwissProt and Expression partners for FRMPD3 Gene

Orthologs for FRMPD3 Gene

This gene was present in the common ancestor of animals.

Orthologs for FRMPD3 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia FRMPD3 35
  • 91.29 (n)
  • 93.02 (a)
  • 93 (a)
(Canis familiaris)
Mammalia FRMPD3 35
  • 89.42 (n)
  • 91.88 (a)
  • 90 (a)
(Mus musculus)
Mammalia LOC101055948 35
  • 88.29 (n)
  • 91.28 (a)
Frmpd3 16
Frmpd3 36
  • 93 (a)
(Pan troglodytes)
Mammalia FRMPD3 35
  • 99.5 (n)
  • 99.45 (a)
  • 100 (a)
(Rattus norvegicus)
Mammalia RGD1563753 35
  • 88.76 (n)
  • 90.87 (a)
(Monodelphis domestica)
Mammalia FRMPD3 36
  • 75 (a)
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 75 (a)
-- 36
  • 83 (a)
(Gallus gallus)
Aves FRMPD3 35
  • 70.07 (n)
  • 71 (a)
  • 70 (a)
(Anolis carolinensis)
Reptilia FRMPD3 36
  • 62 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia frmpd3 35
  • 62.54 (n)
  • 64.86 (a)
(Danio rerio)
Actinopterygii LOC798302 35
  • 60.13 (n)
  • 58.86 (a)
  • 48 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG42788 36
  • 19 (a)
(Caenorhabditis elegans)
Secernentea frm-8 36
  • 22 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 35 (a)
Species with no ortholog for FRMPD3:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for FRMPD3 Gene

Gene Tree for FRMPD3 (if available)
Gene Tree for FRMPD3 (if available)

Paralogs for FRMPD3 Gene

Paralogs for FRMPD3 Gene

genes like me logo Genes that share paralogs with FRMPD3: view

Variants for FRMPD3 Gene

Sequence variations from dbSNP and Humsavar for FRMPD3 Gene

SNP ID Clin Chr 0X pos Sequence Context AA Info Type MAF
rs754716 -- 107,600,074(+) cattg(G/T)gtgag intron-variant
rs754717 -- 107,600,158(+) ATTTC(A/G)TATCA intron-variant
rs1924217 -- 107,592,092(+) ctccc(A/G)ccctt intron-variant
rs2012815 -- 107,599,038(+) gaggc(C/T)gaggt intron-variant
rs2224805 -- 107,577,078(-) caaag(G/T)gTGAT intron-variant

Relevant External Links for FRMPD3 Gene

HapMap Linkage Disequilibrium report
Locus Specific Mutation Databases (LSDB)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for FRMPD3 Gene

Disorders for FRMPD3 Gene

No disorders were found for FRMPD3 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for FRMPD3 Gene

Publications for FRMPD3 Gene

  1. Prediction of the coding sequences of unidentified human genes. XX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PMID: 11347906) Nagase T. … Ohara O. (DNA Res. 2001) 2 3 4
  2. The DNA sequence of the human X chromosome. (PMID: 15772651) Ross M.T. … Bentley D.R. (Nature 2005) 3 4
  3. Toward a confocal subcellular atlas of the human proteome. (PMID: 18029348) Barbe L. … Andersson-Svahn H. (Mol. Cell Proteomics 2008) 3

Products for FRMPD3 Gene

Sources for FRMPD3 Gene

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