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FRMPD2 Gene

protein-coding   GIFtS: 47
GCID: GC10M049364

FERM And PDZ Domain Containing 2

(Previous name: PDZ domain containing 5C)
(Previous symbols: PDZD5C, PDZK5C)
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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
FERM And PDZ Domain Containing 21 2     PDZK42 3
PDZD5C1 2 3     PDZ Domain-Containing Protein 42 3
PDZK5C1 2 3     FERM And PDZ Domain-Containing Protein 22
PDZ Domain Containing 5C1 2     PDZ Domain-Containing Protein 5C3

External Ids:    HGNC: 285721   Entrez Gene: 1431622   Ensembl: ENSG000001703247   OMIM: 6133235   UniProtKB: Q68DX33   

Export aliases for FRMPD2 gene to outside databases

Previous GC identifers: GC10M048710 GC10M049034 GC10M043629


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for FRMPD2 Gene:
This gene encodes a peripheral membrane protein and is located in a region of chromosome 10q that contains a
segmental duplication. This copy of the gene is full-length and is in the telomeric duplicated region. Two other
more centromerically proximal copies of the gene are partial and may represent pseudogenes. This full-length gene
appears to function in the establishment and maintenance of cell polarization. The protein is recruited to
cell-cell junctions in an E-cadherin-dependent manner, and is selectively localized at the basolateral membrane
in polarized epithelial cells. Alternative splicing results in multiple transcript variants. (provided by RefSeq,
Dec 2009)

GeneCards Summary for FRMPD2 Gene:
FRMPD2 (FERM and PDZ domain containing 2) is a protein-coding gene. GO annotations related to this gene include 1-phosphatidylinositol binding. An important paralog of this gene is FRMD1.

UniProtKB/Swiss-Prot: FRPD2_HUMAN, Q68DX3
Function: May play a role in the regulation of tight junction formation. Binds phosphatidylinositol
3,4-bisphosphate (PtdIns(3,4)P2)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000010.10  NC_018921.2  NT_030059.14  
Regulatory elements:
   Regulatory transcription factor binding sites in the FRMPD2 gene promoter:
         CRE-BP1   PPAR-alpha   NF-1   Pbx1a   p300   ATF-2   LCR-F1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidFRMPD2 promoter sequence
   Search Chromatin IP Primers for FRMPD2

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat FRMPD2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 10q11.22   Ensembl cytogenetic band:  10q11.22   HGNC cytogenetic band: 10q11

FRMPD2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
FRMPD2 gene location

GeneLoc information about chromosome 10         GeneLoc Exon Structure

GeneLoc location for GC10M049364:  view genomic region     (about GC identifiers)

Start:
49,364,601 bp from pter      End:
49,482,941 bp from pter
Size:
118,341 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: FRPD2_HUMAN, Q68DX3 (See protein sequence)
Recommended Name: FERM and PDZ domain-containing protein 2  
Size: 1309 amino acids; 144282 Da
Subunit: Interacts (via the PDZ 2 domain) with CTNND2 (via the extreme C-terminus). Interacts (via the PDZ 2
domain) with PKP4 (via the extreme C-terminus); this interaction directed FRMPD2 to the basolateral membranes.
Interacts (via the PDZ 2 domain) with ARVCF (via the extreme C-terminus)
Secondary accessions: B7WNW0 B7ZML5 Q2VY07 Q6GMQ9 Q6ZN38 Q6ZWI2 Q8N5T9
Alternative splicing: 5 isoforms:  Q68DX3-1   Q68DX3-2   Q68DX3-3   Q68DX3-4   Q68DX3-5   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for FRMPD2: NX_Q68DX3

Explore proteomics data for FRMPD2 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See FRMPD2 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (2 alternative transcripts): 
    NP_001018081.3  NP_001035977.2  

    ENSEMBL proteins: 
     ENSP00000422446   ENSP00000363317   ENSP00000307079   ENSP00000384339  

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    antibodies-online proteins for FRMPD2 (2 products) 

     
    antibodies-online peptides for FRMPD2

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    Selected InterPro protein domains (see all 10):
     IPR019748 FERM_central
     IPR019750 Band_41_fam
     IPR011993 PH_like_dom
     IPR014352 FERM/acyl-CoA-bd_prot_3-hlx
     IPR018980 FERM_PH-like_C

    Graphical View of Domain Structure for InterPro Entry Q68DX3

    ProtoNet protein and cluster: Q68DX3

    2 Blocks protein domains:
    IPB000299 Band 4.1 domain
    IPB001478 PDZ/DHR/GLGF domain


    UniProtKB/Swiss-Prot: FRPD2_HUMAN, Q68DX3
    Domain: The FERM and PDZ 2 domains are necessary for localization to the basolateral cell membrane. The FERM
    domain binds to phosphatidylinositol 3,4-bisphosphate (PtdIns(3,4)P2) and is sufficient for membrane localization
    Similarity: Contains 1 FERM domain
    Similarity: Contains 1 KIND domain
    Similarity: Contains 3 PDZ (DHR) domains


    Find genes that share domains with FRMPD2           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: FRPD2_HUMAN, Q68DX3
    Function: May play a role in the regulation of tight junction formation. Binds phosphatidylinositol
    3,4-bisphosphate (PtdIns(3,4)P2)

         Gene Ontology (GO): 3 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI19706687
    GO:00055451-phosphatidylinositol binding IDA19706687
    GO:0016772transferase activity, transferring phosphorus-containing groups ----
         
    Find genes that share ontologies with FRMPD2           About GenesLikeMe


    Animal Models:
       genOway: Develop your customized and physiologically relevant rodent model for FRMPD2

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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    FRPD2_HUMAN, Q68DX3: Cytoplasm (Potential). Basolateral cell membrane. Cell junction, tight junction.
    Note=Colocalizes with CTNNB1, CDH1 and PKP4 at the basolateral membrane. Colocalizes with TJP1 at tight
    junctions. Its recruitment to cell-cell contacts requires CDH1
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    plasma membrane5
    cytoskeleton2
    cytosol2
    extracellular2
    mitochondrion1
    nucleus1
    peroxisome1

    Gene Ontology (GO): 4 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005737cytoplasm IEA--
    GO:0005856cytoskeleton IEA--
    GO:0005923tight junction IDA19706687
    GO:0016323basolateral plasma membrane IDA19706687

    Find genes that share ontologies with FRMPD2           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for FRMPD2
    Interactions:

        Search GeneGlobe Interaction Network for FRMPD2

    STRING Interaction Network Preview (showing 5 interactants - click image to see 6)

    Selected Interacting proteins for FRMPD2 (ENSP000003633174) via UniProtKB, MINT, STRING, and/or I2D (see all 6)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    RALBP1ENSP000000193174STRING: ENSP00000019317
    EFNB3ENSP000002260914STRING: ENSP00000226091
    ACVR2AENSP000002414164STRING: ENSP00000241416
    ACVR2BENSP000003403614STRING: ENSP00000340361
    PTPN14ENSP000003559234STRING: ENSP00000355923
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    Gene Ontology (GO): 1 biological process term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0070830tight junction assembly IMP19706687

    Find genes that share ontologies with FRMPD2           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for FRMPD2 (FRPD2)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for FRMPD2 gene (4 alternative transcripts): 
    NM_001017929.2  NM_152428.4  NM_001018071.3  NM_001042512.2  

    Unigene Cluster for FRMPD2:

    FERM and PDZ domain containing 2
    Hs.664786  [show with all ESTs]
    Unigene Representative Sequence: NM_001018071
    12 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000474573(uc001jgf.3 uc001jgg.3) ENST00000374201(uc001jgi.3)
    ENST00000305531(uc001jgh.3) ENST00000491130 ENST00000463706(uc001jgk.3)
    ENST00000477710 ENST00000486151 ENST00000494505 ENST00000505547 ENST00000468556
    ENST00000492045 ENST00000407470(uc001jgj.3)
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    6 qRT-PCR Assays for microRNAs that regulate FRMPD2:
    hsa-miR-3678-3p hsa-miR-4328 hsa-miR-19b hsa-miR-330-3p hsa-miR-3919 hsa-miR-19a
    SwitchGear 3'UTR luciferase reporter plasmidFRMPD2 3' UTR sequence
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    Additional mRNA sequence: 

    AK123038.1 AK303923.1 AY491519.1 BC031614.1 BC040910.1 BC073954.1 BC110798.1 CR749241.1 

    9 DOTS entries:

    DT.442272  DT.97825660  DT.95367494  DT.101963149  DT.75142706  DT.97801744  DT.75188729  DT.121272101 
    DT.121272081 

    Selected AceView cDNA sequences (see all 34):

    H18873 AA774713 F11220 F08883 BC071635 AA774714 BC040910 BI757732 
    BI822016 BX281170 BI914716 BV204841 BI820278 BM544519 T17219 BX952001 
    BM560056 BC072395 BM921688 AI138818 BX492711 AW172672 BG213711 R66455 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for FRMPD2 (see all 7)    About this scheme

    ExUns: 1a · 1b ^ 2a · 2b ^ 3 ^ 4a · 4b ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12 ^ 13 ^ 14 ^ 15 ^ 16 ^ 17 ^ 18 ^ 19 ^ 20 ^ 21 ^ 22a · 22b ·
    SP1:                          -           -                                                                                                     -           -   
    SP2:                                      -                                   -     -                                                           -               
    SP3:                                                                                                                                                            
    SP4:                                                                                                                                                            
    SP5:                                                                                                                                                            

    ExUns: 22c ^ 23a · 23b ^ 24 ^ 25a · 25b · 25c ^ 26 ^ 27 ^ 28 ^ 29 ^ 30 ^ 31a · 31b
    SP1:  -     -     -           -                                         -               
    SP2:                                                                                    
    SP3:  -     -     -           -                                                         
    SP4:                          -                                         -               
    SP5:                                                                    -               


    ECgene alternative splicing isoforms for FRMPD2

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    FRMPD2 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    FRMPD2 Expression
    About this image

    FRMPD2 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    FRMPD2 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.664786

    UniProtKB/Swiss-Prot: FRPD2_HUMAN, Q68DX3
    Tissue specificity: Expressed in epithelial cells

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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for FRMPD2 gene from Selected species (see all 10)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Gm6261 predicted gene 626 79.64(n)
    74.05(a)
      268729  XM_006519762.1  XP_006519825.1 
    chicken
    (Gallus gallus)
    Aves FRMPD26
    FERM and PDZ domain containing 2
    40(a)
    1 ↔ 1
    6(17739307-17760651)
    zebrafish
    (Danio rerio)
    Actinopterygii FRMPD2 (1 of 2)6
    ptpn206
    FERM and PDZ domain containing 2
    protein tyrosine phosphatase, non-receptor type 20...
    37(a)
    20(a)
    many → 1
    many → 1
    12(2787401-2833219) ENSDARG00000074119
    13(31401425-31454811) ENSDARG00000075459
    worm
    (Caenorhabditis elegans)
    Secernentea frm-5.26
    frm-5.16
    Protein FRM-5.2
    Protein FRM-5.1, isoform b (frm-5.1) mRNA, complet...
    17(a)
    15(a)
    many ↔ many
    many ↔ many
    IV(695-14926) WBGene00021406
    IV(32953-48844) WBGene00001492


    ENSEMBL Gene Tree for FRMPD2 (if available)
    TreeFam Gene Tree for FRMPD2 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for FRMPD2 gene
    FRMD12  FRMD62  PTPN132  
    14 SIMAP similar genes for FRMPD2 using alignment to 3 protein entries:     FRPD2_HUMAN (see all proteins):
    FRMPD2P1    FRMPD2P2    FRMPD2L2    DLG4    IL16    PTPN4
    SCRIB    FRMD6    TJP2    PTPN21    RADIL    RDX
    PTPN13    TAX1BP3

    Find genes that share paralogs with FRMPD2           About GenesLikeMe


    2 Pseudogenes.org Pseudogenes for FRMPD2
    PGOHUM00000257779 PGOHUM00000257780


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for FRMPD2 (see all 2335)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 10 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    VAR_0354464
    A colorectal cancer sample4--see VAR_0354462 R W mis40--------
    rs1487172001,2
    Cuntested149392827(+) TTGATC/TGTTTT 2 T syn11Minor allele frequency- T:0.00NA 4510
    rs1926656331,2
    C--49364723(+) GGGGGA/GTGGGG 2 -- ut310--------
    rs1849467881,2
    --49365176(+) CCCCGC/TGGAAG 2 -- ut310--------
    rs2000226421,2
    C--49365686(+) CATGAA/GAGCTA 2 -- int10--------
    rs1875127521,2
    --49366471(+) AAGGGA/CAAGAC 2 -- int10--------
    rs1912994061,2
    --49367146(+) TTGTGC/TCCCTT 2 -- int10--------
    rs1499521691,2
    --49367212(+) TGACAC/GAGCTG 2 -- int10--------
    rs1837598361,2
    --49367542(+) CATGAC/TATCTC 2 -- int10--------
    rs1893096021,2
    --49367791(+) CTTACA/GTGCAT 2 -- int10--------

    HapMap Linkage Disequilibrium report for FRMPD2 (49364601 - 49482941 bp)

    Structural Variations
         Database of Genomic Variants (DGV) Selected variations for FRMPD2 (see all 22):    About this table    
    Variant IDTypeSubtypePubMed ID
    esv1001778CNV Deletion20482838
    nsv820931CNV Deletion20802225
    nsv436102CNV Deletion17901297
    nsv6565CNV Insertion18451855
    nsv6576CNV Insertion18451855
    nsv895365CNV Loss21882294
    nsv895363CNV Loss21882294
    nsv8639CNV Loss18304495
    nsv895368CNV Gain21882294
    nsv895370CNV Gain21882294

    Site Specific Mutation Identification with PCR Assays
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 613323    OMIM disorders: --


    Find genes that share disorders with FRMPD2           About GenesLikeMe

    Genetic Association Database (GAD): FRMPD2
    Human Genome Epidemiology (HuGE) Navigator: FRMPD2 (2 documents)

    Export disorders for FRMPD2 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for FRMPD2 gene, integrated from 10 sources (see all 12):
    (articles sorted by number of sources associating them with FRMPD2)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (Mol. Med. 2010)
    2. PDZ-domain-directed basolateral targeting of the peripheral membrane protein FRMPD2 in epithelial cells. (PubMed id 19706687)1, 2 Stenzel N.... Erdmann K.S. (J. Cell Sci. 2009)
    3. A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease. (PubMed id 16385451)1, 4 Grupe A....Goate A. (Am. J. Hum. Genet. 2006)
    4. Interaction between very-KIND Ras guanine exchange factor and microtubule-associated protein 2, and its role in dendrite growth--structure and function of the second kinase noncatalytic C-lobe domain. (PubMed id 21385318)1 Huang J....Furuichi T. (FEBS J. 2011)
    5. hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PubMed id 17207965)1 Lamesch P.... Vidal M. (Genomics 2007)
    6. The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005)2 Bechtel S.... Schupp I. (BMC Genomics 2007)
    7. The consensus coding sequences of human breast and colorectal cancers. (PubMed id 16959974)2 Sjoeblom T.... Velculescu V.E. (Science 2006)
    8. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    9. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)2 Ota T.... Sugano S. (Nat. Genet. 2004)
    10. The DNA sequence and comparative analysis of human chromosome 10. (PubMed id 15164054)2 Deloukas P.... Rogers J. (Nature 2004)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 143162 HGNC: 28572 AceView: FRMPD2.2 Ensembl:ENSG00000170324 euGenes: HUgn143162
    ECgene: FRMPD2 H-InvDB: FRMPD2

    (According to HUGE)
    About This Section

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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

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    NameDescription
    PharmGKB entry for FRMPD2 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

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    Patent Information for FRMPD2 gene:
    Search GeneIP for patents involving FRMPD2

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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