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FRMD8 Gene

protein-coding   GIFtS: 48
GCID: GC11P065154

FERM Domain Containing 8

  Search for FRMD8
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
FERM Domain Containing 81 2
FKSG442
FERM Domain-Containing Protein 82

External Ids:    HGNC: 254621   Entrez Gene: 837862   Ensembl: ENSG000001263917   UniProtKB: Q9BZ673   

Export aliases for FRMD8 gene to outside databases

Previous GC identifers: GC11P064911 GC11P061480


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for FRMD8 Gene:
FRMD8 (FERM domain containing 8) is a protein-coding gene. An important paralog of this gene is KRIT1.


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000011.9  NT_167190.2  NC_018922.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the FRMD8 gene promoter:
         RP58   Sp1   Lmo2   HNF-4alpha2   HNF-4alpha1   AREB6   HSF2   SEF-1 (1)   Pax-4a   ATF6   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidFRMD8 promoter sequence
   Search Chromatin IP Primers for FRMD8

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat FRMD8


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 11q13   Ensembl cytogenetic band:  11q13.1   HGNC cytogenetic band: 11q13.1

FRMD8 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
FRMD8 gene location

GeneLoc information about chromosome 11         GeneLoc Exon Structure

GeneLoc location for GC11P065154:  view genomic region     (about GC identifiers)

Start:
65,154,041 bp from pter      End:
65,180,996 bp from pter
Size:
26,956 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: FRMD8_HUMAN, Q9BZ67 (See protein sequence)
Recommended Name: FERM domain-containing protein 8  
Size: 464 amino acids; 51218 Da
Secondary accessions: Q86V56 Q8NCB5
Alternative splicing: 2 isoforms:  Q9BZ67-1   Q9BZ67-2   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for FRMD8: NX_Q9BZ67

Explore proteomics data for FRMD8 at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys153
  • Modification sites at PhosphoSitePlus

  • See FRMD8 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_114110.1  
    ENSEMBL proteins: 
     ENSP00000319726   ENSP00000433479   ENSP00000435913   ENSP00000348270   ENSP00000392111  
     ENSP00000435991   ENSP00000434274  

    FRMD8 Human Recombinant Protein Products:

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    Cloud-Clone Corp. Proteins for FRMD8

     
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    FRMD8 Assay Products:

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    Cloud-Clone Corp. ELISAs for FRMD8
    Cloud-Clone Corp. CLIAs for FRMD8
    Search eBioscience for ELISAs for FRMD8 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    4 InterPro protein domains:
     IPR019748 FERM_central
     IPR014352 FERM/acyl-CoA-bd_prot_3-hlx
     IPR019749 Band_41_domain
     IPR000299 FERM_domain

    Graphical View of Domain Structure for InterPro Entry Q9BZ67

    ProtoNet protein and cluster: Q9BZ67

    UniProtKB/Swiss-Prot: FRMD8_HUMAN, Q9BZ67
    Similarity: Contains 1 FERM domain


    Find genes that share domains with FRMD8           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Phenotypes:
         1 GenomeRNAi human phenotype for FRMD8:
     Increased cell number in G2M,  

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for FRMD8
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       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for FRMD8
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for FRMD8

    miRNA
    Products:
        
    miRTarBase miRNAs that target FRMD8:
    hsa-mir-124-3p (MIRT023130), hsa-mir-874-3p (MIRT037767)

    Block miRNA regulation of human, mouse, rat FRMD8 using miScript Target Protectors
    8 qRT-PCR Assays for microRNAs that regulate FRMD8:
    hsa-miR-3910 hsa-miR-4324 hsa-miR-186* hsa-miR-124 hsa-miR-2355-3p hsa-miR-186 hsa-miR-506 hsa-miR-3714
    SwitchGear 3'UTR luciferase reporter plasmidFRMD8 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for FRMD8
    Predesigned siRNA for gene silencing in human, mouse, rat FRMD8

    Gene Editing
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    Clone
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    OriGene clones in human, mouse for FRMD8 (see all 7)
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    GenScript: all cDNA clones in your preferred vector: FRMD8 (NM_031904)
    Browse Sino Biological Human cDNA Clones
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FRMD8

    Cell Line
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    Browse ESI BIO Cell Lines and PureStem Progenitors for FRMD8 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FRMD8


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytoskeleton2
    cytosol2
    extracellular1
    mitochondrion1
    nucleus1
    peroxisome1
    plasma membrane1

    Gene Ontology (GO): 1 cellular component term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005856cytoskeleton IEA--

    Find genes that share ontologies with FRMD8           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for FRMD8
    Interactions:

        Search GeneGlobe Interaction Network for FRMD8

    STRING Interaction Network Preview (showing 3 interactants - click image to see more details)

    3 Interacting proteins for FRMD8 (Q9BZ673 ENSP000003197264) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    IKBKGQ9Y6K93, ENSP000003586224I2D: score=1 STRING: ENSP00000358622
    UBCENSP000003448184STRING: ENSP00000344818
    ELAVL1ENSP000003852694STRING: ENSP00000385269
    About this table

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for FRMD8



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for FRMD8 gene: 
    NM_031904.3  

    Unigene Cluster for FRMD8:

    FERM domain containing 8
    Hs.578433  [show with all ESTs]
    Unigene Representative Sequence: NM_031904
    9 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000317568(uc001odu.4 uc009yqj.3 uc010rof.2) ENST00000531296
    ENST00000528854 ENST00000533782 ENST00000355991 ENST00000416776 ENST00000526201
    ENST00000525156 ENST00000531151
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat FRMD8 using miScript Target Protectors
    8 qRT-PCR Assays for microRNAs that regulate FRMD8:
    hsa-miR-3910 hsa-miR-4324 hsa-miR-186* hsa-miR-124 hsa-miR-2355-3p hsa-miR-186 hsa-miR-506 hsa-miR-3714
    SwitchGear 3'UTR luciferase reporter plasmidFRMD8 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for FRMD8
    Predesigned siRNA for gene silencing in human, mouse, rat FRMD8
    Clone
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    OriGene clones in human, mouse for FRMD8 (see all 7)
    OriGene ORF clones in mouse, rat for FRMD8
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: FRMD8 (NM_031904)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for FRMD8
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FRMD8
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for FRMD8
    OriGene qSTAR qPCR primer pairs in human, mouse for FRMD8
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat FRMD8
      QuantiTect SYBR Green Assays in human, mouse, rat FRMD8
      QuantiFast Probe-based Assays in human, mouse, rat FRMD8

    Additional mRNA sequence: 

    AF334946.1 AK074850.1 AK291678.1 AK304363.1 BC014498.1 BC033851.1 BC044658.1 BC051695.1 

    8 DOTS entries:

    DT.40246641  DT.100035874  DT.101983291  DT.120760787  DT.120760796  DT.95264787  DT.100035876  DT.100714081 

    Selected AceView cDNA sequences (see all 74):

    BC033851 CR608928 AI149817 C00641 AI148972 T69758 AI338209 BQ939908 
    BG755699 BF435515 BI559570 BX090741 AA311352 BI562673 AW958316 BC014498 
    BM551925 AW150399 N55476 BI546793 BX110843 T98936 NM_031904 CA434756 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    FRMD8 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TGACTTATTA
    FRMD8 Expression
    About this image


    FRMD8 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     
     Bone (Muscoskeletal System)    fully expand to see all 2 entries
             Endochondral Facial Bones
    FRMD8 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    FRMD8 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.578433
        Custom PCR Arrays for FRMD8
    Primer
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FRMD8

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for FRMD8 gene from Selected species (see all 15)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Frmd81 , 5 FERM domain containing 81, 5 84.59(n)1
    88.12(a)1
      19 (4.34 cM)5
    674571  NM_026169.41  NP_080445.11 
     58497025 
    lizard
    (Anolis carolinensis)
    Reptilia FRMD86
    FERM domain containing 8
    63(a)
    1 ↔ 1
    GL343801.1(117172-127154)
    African clawed frog
    (Xenopus laevis)
    Amphibia MGC537542 hypothetical protein MGC53754 73.6(n)    BC046857.1 
    zebrafish
    (Danio rerio)
    Actinopterygii frmd81 FERM domain containing 8 59.46(n)
    57.93(a)
      559410  XM_682750.6  XP_687842.2 
    fruit fly
    (Drosophila melanogaster)
    Insecta Bili1 Band4.1 inhibitor LRP interactor 49.25(n)
    40.07(a)
      43019  NM_001170252.1  NP_001163723.1 
    worm
    (Caenorhabditis elegans)
    Secernentea frm-106
    Protein FRM-10, isoform a
    16(a)
    1 ↔ 1
    V(13463150-13467226) WBGene00001496


    ENSEMBL Gene Tree for FRMD8 (if available)
    TreeFam Gene Tree for FRMD8 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for FRMD8 gene
    KRIT12  
    1 SIMAP similar gene for FRMD8 using alignment to 6 protein entries:     FRMD8_HUMAN (see all proteins):
    FRMD8P1

    Find genes that share paralogs with FRMD8           About GenesLikeMe


    1 Pseudogenes.org Pseudogene for FRMD8
    PGOHUM00000241357


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for FRMD8 (see all 613)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 11 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1824205621,2
    --65152161(+) GGCAAG/TGCTGT 1 -- us2k10--------
    rs116015391,2
    C,F,H--65152253(+) atcagA/Cgctca 1 -- us2k14Minor allele frequency- C:0.07NA 128
    rs1870518661,2
    --65152355(+) ATTTTG/TGGGTT 1 -- us2k10--------
    rs1144247471,2
    F--65152373(+) GATGGC/TGTCTC 1 -- us2k11Minor allele frequency- T:0.03WA 118
    rs1895397811,2
    --65152389(+) GTTCCC/GCAGGC 1 -- us2k10--------
    rs1823586611,2
    --65152419(+) TCAGGC/TGATCC 1 -- us2k10--------
    rs1887407271,2
    --65152762(+) TCTGAA/GCTTCC 1 -- us2k10--------
    rs1462946431,2
    --65153015(+) AAGGTA/GCCCCA 1 -- us2k10--------
    rs1392634391,2
    C--65153207(+) CTCATA/GTCACT 1 -- us2k10--------
    rs1154505811,2
    C,F--65153253(+) CTGATT/ATAGAC 1 -- us2k11Minor allele frequency- A:0.13WA 118

    HapMap Linkage Disequilibrium report for FRMD8 (65154041 - 65180996 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 6 variations for FRMD8:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2422285CNV Deletion17116639
    nsv897717CNV Loss21882294
    nsv897719CNV Loss21882294
    dgv1175n71CNV Loss21882294
    nsv897718CNV Loss21882294
    nsv526181CNV Gain19592680

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing FRMD8
    DNA2.0 Custom Variant and Variant Library Synthesis for FRMD8

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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      --

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for FRMD8 gene, integrated from 10 sources (see all 18):
    (articles sorted by number of sources associating them with FRMD8)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1, 3 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)
    3. Pathway Analysis of ChIP-Seq-Based NRF1 Target Genes Suggests a Logical Hypothesis of their Involvement in the Pathogenesis of Neurodegenerative Diseases. (PubMed id 24250222)1 Satoh J....Yamamoto Y. (Gene Regul Syst Bio 2013)
    4. Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass. (PubMed id 23000965)1 Povlsen L.K....Choudhary C. (Nat. Cell Biol. 2012)
    5. Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (amp 2012)
    6. N-terminal acetylome analyses and functional insights of the N- terminal acetyltransferase NatB. (PubMed id 22814378)2 Van Damme P....Aldabe R. (Proc. Natl. Acad. Sci. U.S.A. 2012)
    7. Systematic and quantitative assessment of the ubiquitin-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (Mol. Cell 2011)
    8. Interactions of pathological hallmark proteins: tubulin polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. (PubMed id 21832049)1 OlA!h J....OvA!di J. (J. Biol. Chem. 2011)
    9. Mass spectrometric analysis of lysine ubiquitylation reveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (amp 2011)
    10. Global identification of modular cullin-RING ligase substrates. (PubMed id 21963094)1 Emanuele M.J....Elledge S.J. (Cell 2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 83786 HGNC: 25462 AceView: FKSG44 Ensembl:ENSG00000126391 euGenes: HUgn83786
    ECgene: FRMD8 H-InvDB: FRMD8

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for FRMD8 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for FRMD8 gene:
    Search GeneIP for patents involving FRMD8

    GeneCards and IP:
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    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
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     Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
     Browse OriGene Antibodies   OriGene RNAi products in human, mouse, rat for FRMD8  
     OriGene qPCR primer pairs and template standards for FRMD8   OriGene Protein Over-expression Lysate for FRMD8  
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     OriGene Custom Antibody Services for FRMD8   OriGene Custom Protein Services for FRMD8  

     
     
     Block miRNA regulation of human, mouse, rat FRMD8 using miScript Target Protectors SeqTarget long-range PCR primers for resequencing FRMD8
     DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat FRMD8 Predesigned siRNA for gene silencing in human, mouse, rat FRMD8
     QuantiFast Probe-based Assays in human, mouse, rat FRMD8 QuantiTect SYBR Green Assays in human, mouse, rat FRMD8
     Custom PCR Arrays for FRMD8 Search Chromatin IP Primers for FRMD8
     Pre-validated RT2 qPCR Primer Assay in human, mouse, rat FRMD8  Search GeneGlobe Interaction Network for FRMD8
     Regulatory tfbs in FRMD8 promoter
     GenScript Custom Purified and Recombinant Proteins Services for FRMD8 GenScript cDNA clones with any tag delivered in your preferred vector for FRMD8
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     Vector-based siRNA and miRNA, Ready for Transfection Gene Mutant Library, Variants up to 10^11
     Plasmid Preparation Custom Peptide Services
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     Search Tocris compounds for FRMD8
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     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

     Novus Tissue Slides
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     Browse ProSpec Recombinant Proteins
     Proteins for FRMD8
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     Browse ESI BIO Cell Lines and PureStem Progenitors for FRMD8
     Gene Synthesis
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     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FRMD8
     SwitchGear 3'UTR luciferase reporter plasmids for FRMD8
     SwitchGear Promoter luciferase reporter plasmids for FRMD8
     ThermoFisher Antibodies for FRMD8
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FRMD8
     inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for FRMD8
     inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for FRMD8
     LSBio Antibodies in human, mouse, rat for FRMD8
    Customized transgenic rodents for:
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     Browse compounds at ApexBio
     Search Addgene for plasmids for FRMD8
      Search eBioscience for proteins for FRMD8
      Search eBioscience for elisas for FRMD8
      eBioscience FlowRNA Probe Sets
           
    GeneCards Homepage - Last full update: 7 May 2014 - Incrementals: 9 May 2014 , 2 Jun 2014 , 26 Jun 2014 , 30 Jun 2014 , 21 Aug 2014 , 8 Sep 2014

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