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FRMD5 Gene

protein-coding   GIFtS: 47
GCID: GC15M044162

FERM Domain Containing 5

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
FERM Domain Containing 51 2
FERM Domain-Containing Protein 52

External Ids:    HGNC: 282141   Entrez Gene: 849782   Ensembl: ENSG000001718777   UniProtKB: Q7Z6J63   

Export aliases for FRMD5 gene to outside databases

Previous GC identifers: GC15M041953 GC15M020989


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for FRMD5 Gene:
FRMD5 (FERM domain containing 5) is a protein-coding gene. Diseases associated with FRMD5 include cervicitis, and endotheliitis. GO annotations related to this gene include cytoskeletal protein binding. An important paralog of this gene is EPB41L5.


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000015.10  NT_010194.18  NC_018926.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the FRMD5 gene promoter:
         HNF-1A   E47   GATA-1   IRF-2   POU2F1   HSF2   POU2F1a   HNF-1   Cart-1   Sox9   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidFRMD5 promoter sequence
   Search Chromatin IP Primers for FRMD5

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat FRMD5


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 15q15.3   Ensembl cytogenetic band:  15q15.3   HGNC cytogenetic band: 15q15.3

FRMD5 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
FRMD5 gene location

GeneLoc information about chromosome 15         GeneLoc Exon Structure

GeneLoc location for GC15M044162:  view genomic region     (about GC identifiers)

Start:
44,162,962 bp from pter      End:
44,487,450 bp from pter
Size:
324,489 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
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UniProtKB/Swiss-Prot: FRMD5_HUMAN, Q7Z6J6 (See protein sequence)
Recommended Name: FERM domain-containing protein 5  
Size: 570 amino acids; 65065 Da
Secondary accessions: Q8NBG4
Alternative splicing: 2 isoforms:  Q7Z6J6-1   Q7Z6J6-2   

Explore the universe of human proteins at neXtProt for FRMD5: NX_Q7Z6J6

Explore proteomics data for FRMD5 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See FRMD5 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (3 alternative transcripts): 
    NP_001273419.1  NP_001273420.1  NP_116281.2  

    ENSEMBL proteins: 
     ENSP00000403067   ENSP00000384142   ENSP00000399684   ENSP00000452968   ENSP00000404496  
     ENSP00000401635   ENSP00000454031   ENSP00000392786  

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    Cloud-Clone Corp. CLIAs for FRMD5


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    Selected InterPro protein domains (see all 11):
     IPR019748 FERM_central
     IPR019750 Band_41_fam
     IPR000798 Ez/rad/moesin_like
     IPR019747 FERM_CS
     IPR011993 PH_like_dom

    Graphical View of Domain Structure for InterPro Entry Q7Z6J6

    ProtoNet protein and cluster: Q7Z6J6

    1 Blocks protein domain: IPB000299 Band 4.1 domain

    UniProtKB/Swiss-Prot: FRMD5_HUMAN, Q7Z6J6
    Similarity: Contains 1 FERM domain


    FRMD5 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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         Gene Ontology (GO): 3 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003674molecular_function ND--
    GO:0005515protein binding IPI--
    GO:0008092cytoskeletal protein binding IEA--
         
    FRMD5 for ontologies           About GeneDecksing


    Phenotypes:
         1 MGI phenotypic allele for Frmd5 (no phenotypes)

    FRMD5 for phenotypes           About GeneDecksing

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for FRMD5
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       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for FRMD5
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for FRMD5

    miRNA
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    Block miRNA regulation of human, mouse, rat FRMD5 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate FRMD5 (see all 12):
    hsa-miR-188-5p hsa-miR-218-2* hsa-miR-218-1* hsa-miR-765 hsa-miR-551b* hsa-miR-548aa hsa-miR-211 hsa-miR-4314
    SwitchGear 3'UTR luciferase reporter plasmidFRMD5 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for FRMD5
    Predesigned siRNA for gene silencing in human, mouse, rat FRMD5

    Gene Editing
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    GenScript: all cDNA clones in your preferred vector: FRMD5 (NM_032892)
    Sino Biological Human cDNA Clone for FRMD5
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FRMD5

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    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FRMD5


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    FRMD5_HUMAN, Q7Z6J6: Membrane; Single-pass membrane protein (Potential)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytosol3
    cytoskeleton2
    nucleus2
    extracellular1
    golgi apparatus1
    peroxisome1
    plasma membrane1

    Gene Ontology (GO): 5 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005575cellular_component ND--
    GO:0005737cytoplasm IEA--
    GO:0005856cytoskeleton IEA--
    GO:0016021integral component of membrane IEA--
    GO:0019898extrinsic component of membrane IEA--

    FRMD5 for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for FRMD5
    Interactions:

        Search GeneGlobe Interaction Network for FRMD5

    5 Interacting proteins for FRMD5 (Q7Z6J61, 2, 3) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    CTNND1O607161, 2EBI-727282,EBI-701927 MINT-8385411 MINT-8385398 MINT-8385383
    NELFCDQ8IXH72, 3MINT-64860 I2D: score=4 
    CDH1P128302MINT-8385411
    CTNNB1P352222MINT-8385358
    JUPP149232MINT-8385372
    About this table

    Gene Ontology (GO): 1 biological process term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0008150biological_process ND--

    FRMD5 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for FRMD5



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for FRMD5 gene (3 alternative transcripts): 
    NM_001286490.1  NM_001286491.1  NM_032892.4  

    Unigene Cluster for FRMD5:

    FERM domain containing 5
    Hs.578544  [show with all ESTs]
    Unigene Representative Sequence: BC007796
    10 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000417257(uc001ztl.3) ENST00000402883 ENST00000449926(uc001ztj.1)
    ENST00000484674(uc001ztk.1) ENST00000458630(uc010uef.2) ENST00000421674(uc001ztm.3 uc001ztn.3)
    ENST00000558108 ENST00000451277 ENST00000473965 ENST00000479319
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat FRMD5 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate FRMD5 (see all 12):
    hsa-miR-188-5p hsa-miR-218-2* hsa-miR-218-1* hsa-miR-765 hsa-miR-551b* hsa-miR-548aa hsa-miR-211 hsa-miR-4314
    SwitchGear 3'UTR luciferase reporter plasmidFRMD5 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for FRMD5
    Predesigned siRNA for gene silencing in human, mouse, rat FRMD5
    Clone
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    OriGene clones in human, mouse for FRMD5 (see all 7)
    OriGene ORF clones in mouse, rat for FRMD5
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: FRMD5 (NM_032892)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for FRMD5
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FRMD5
    Primer
    Products:
        
    OriGene qSTAR qPCR primer pairs in human, mouse for FRMD5
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat FRMD5
      QuantiTect SYBR Green Assays in human, mouse, rat FRMD5
      QuantiFast Probe-based Assays in human, mouse, rat FRMD5

    Additional mRNA sequence: 

    AK090572.1 AK123018.1 AK290013.1 BC007796.2 BC020191.1 BC043486.2 BC053647.1 

    5 DOTS entries:

    DT.100754305  DT.97804479  DT.101982289  DT.75170218  DT.95279505 

    Selected AceView cDNA sequences (see all 51):

    BC020191 AW294986 BC007796 BQ638832 Z42067 AI287558 AI421905 BM549537 
    BX280430 BC053647 F03248 NM_032892 BM468625 AW473478 BX281755 BE907901 
    CD251954 BC043486 AA012975 BQ646863 CF457249 BX645122 AK123018 AI417669 

    GeneLoc Exon Structure

    4 Alternative Splicing Database (ASD) splice patterns (SP) for FRMD5    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3a · 3b ^ 4a · 4b ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12 ^ 13a · 13b ^ 14 ^ 15 ^ 16
    SP1:                                                  -                                                                     
    SP2:                                                                          -                       -                     
    SP3:                                            -     -                                               -                     
    SP4:                          -     -           -     -                                               -                     


    ECgene alternative splicing isoforms for FRMD5

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    FRMD5 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TAGAATGATT
    FRMD5 Expression
    About this image


    FRMD5 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 4) fully expand
     
     Endothelium (Cardiovascular System)    fully expand to see all 3 entries
             Adult Endothelial Cells Blood Brain Barrier
     
     Brain (Nervous System)    fully expand to see all 3 entries
             Adult Endothelial Cells Blood Brain Barrier
     
     Neurons
             GABAergic Amacrine Cells Inner Nuclear Layer
     
     Eye (Sensory Organs)
             GABAergic Amacrine Cells Inner Nuclear Layer
    FRMD5 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    FRMD5 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.578544
        Custom PCR Arrays for FRMD5
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FRMD5

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for FRMD5 gene from Selected species (see all 12)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Frmd51 , 5 FERM domain containing 51, 5 91.82(n)1
    98.38(a)1
      2 (60.42 cM)5
    2285641  NM_172673.31  NP_766261.21 
     1215455295 
    chicken
    (Gallus gallus)
    Aves FRMD51 FERM domain containing 5 83.16(n)
    92.61(a)
      415576  XM_413944.4  XP_413944.3 
    lizard
    (Anolis carolinensis)
    Reptilia FRMD56
    FERM domain containing 5
    87(a)
    1 ↔ 1
    GL343795.1(150290-195699)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia frmd51 FERM domain containing 5 70.86(n)
    76.26(a)
      100492108  XM_002932962.2  XP_002933008.2 
    zebrafish
    (Danio rerio)
    Actinopterygii LOC5709031 novel FERM domain containing protein 77.35(n)
    86.97(a)
      570903  XM_694434.6  XP_699526.3 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG50226
    --
    28(a)
    1 → many
    2L(10344442-10347706)


    ENSEMBL Gene Tree for FRMD5 (if available)
    TreeFam Gene Tree for FRMD5 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for FRMD5 gene
    EPB41L52  EPB412  FRMD32  EPB41L12  PTPN32  EPB41L4B2  FARP12  PTPN42  
    FRMD72  EPB41L32  EPB41L4A2  FARP22  EPB41L22  
    17 SIMAP similar genes for FRMD5 using alignment to 9 protein entries:     FRMD5_HUMAN (see all proteins):
    FRMD3    EPB41L1    EPB41L3    PTPN4    EPB41L4A    FARP1
    EPB41L2    EPB41    EPB41L5    RDX    PTPN3    EPB41L4B
    FRMD4B    PTPN14    EZR-ROS1    FARP2    EZR

    FRMD5 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for FRMD5 (see all 5499)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 15 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs595378641,2
    C--24478801(+) TTTTT-/TTT   
       
    /TTTT
    AAGTT
    1 -- int11NA 2
    rs1922126811,2
    --44165248(+) TAACGC/GCCCTG 1 -- int10--------
    rs791391251,2
    F--44165282(+) TCTTCG/AGAAAA 1 -- int11Minor allele frequency- A:0.12WA 118
    rs1820086661,2
    --44165284(+) TTCGGA/GAAAAA 1 -- int10--------
    rs1858516061,2
    --44165297(+) AATCAC/TGTTAA 1 -- int10--------
    rs1468846591,2
    C,F--44165368(+) ACTTAC/TCCCAC 1 -- int11Minor allele frequency- T:0.01EU 567
    rs1478940241,2
    C--44165538(+) CTGGC-/AAAAAA 1 -- int10--------
    rs38302851,2
    C--44165545(+) ACAAA-/A/CAAA
            
    AAACT
    1 -- int10--------
    rs1417040111,2
    C--44165558(+) AAACT-/AAAC  
            
    AAACA
    1 -- int10--------
    rs1905082151,2
    --44165612(+) GTGATA/GAGTCT 1 -- int10--------

    HapMap Linkage Disequilibrium report for FRMD5 (44162962 - 44412962 bp, first 250kb of FRMD5)

    Structural Variations
         Database of Genomic Variants (DGV) 8 variations for FRMD5:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2749628CNV Deletion23290073
    esv2676192CNV Deletion23128226
    nsv1515CNV Insertion18451855
    esv1620375CNV Insertion17803354
    nsv904176CNV Loss21882294
    nsv94497CNV Loss16902084
    dgv2376n71CNV Loss21882294
    nsv832989CNV Gain+Loss17160897

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing FRMD5
    DNA2.0 Custom Variant and Variant Library Synthesis for FRMD5

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    2 diseases for FRMD5:    
    About MalaCards
    cervicitis    endotheliitis


    FRMD5 for disorders           About GeneDecksing

    Genetic Association Database (GAD): FRMD5

    Export disorders for FRMD5 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for FRMD5 gene, integrated from 10 sources (see all 12):
    (articles sorted by number of sources associating them with FRMD5)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Biological, clinical and population relevance of 95 loci for blood lipids. (PubMed id 20686565)1, 4 Teslovich T.M....Kathiresan S. (Nature 2010)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    4. FERM-containing protein FRMD5 is a p120-catenin interacting protein that regulates tumor progression. (PubMed id 22846708)1 Wang T....Zhang H. (FEBS Lett. 2012)
    5. Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass. (PubMed id 23000965)1 Povlsen L.K....Choudhary C. (Nat. Cell Biol. 2012)
    6. Discovery and fine mapping of serum protein loci through transethnic meta-analysis. (PubMed id 23022100)1 Franceschini N....Morris A.P. (Am. J. Hum. Genet. 2012)
    7. Mass spectrometric analysis of lysine ubiquitylation reveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (amp 2011)
    8. A quantitative atlas of mitotic phosphorylation. (PubMed id 18669648)2 Dephoure N.... Gygi S.P. (Proc. Natl. Acad. Sci. U.S.A. 2008)
    9. Toward a confocal subcellular atlas of the human proteome. (PubMed id 18029348)1 Barbe L....Andersson-Svahn H. (amp 2008)
    10. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (Genome Res. 2006)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    Aliases
    Free Text  

      Query String
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    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 84978 HGNC: 28214 AceView: MGC14161 Ensembl:ENSG00000171877 euGenes: HUgn84978
    ECgene: FRMD5 H-InvDB: FRMD5

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

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    NameDescription
    PharmGKB entry for FRMD5 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for FRMD5 gene:
    Search GeneIP for patents involving FRMD5

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, and ESI BIO, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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