External Ids for FRMD5 Gene
Previous GeneCards Identifiers for FRMD5 Gene
GeneCards Summary for FRMD5 Gene
FRMD5 (FERM Domain Containing 5) is a Protein Coding gene. GO annotations related to this gene include cytoskeletal protein binding. An important paralog of this gene is FRMD3.
UniProtKB/Swiss-Prot for FRMD5 Gene
May be involved in regulation of cell migration (PubMed:22846708, PubMed:25448675). May regulate cell-matrix interactions via its interaction with ITGB5 and modifying ITGB5 cytoplasmic tail interactions such as with FERMT2 and TLN1. May regulate ROCK1 kinase activity possibly involved in regulation of actin stress fiber formation (PubMed:25448675).