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FRMD4B Gene

protein-coding   GIFtS: 46
GCID: GC03M069219

FERM Domain Containing 4B

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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
FERM Domain Containing 4B1 2
GRP1-Binding Protein GRSP12 3
6030440G05Rik2
GRSP12
FERM Domain-Containing Protein 4B2
KIAA10133

External Ids:    HGNC: 248861   Entrez Gene: 231502   Ensembl: ENSG000001145417   UniProtKB: Q9Y2L63   

Export aliases for FRMD4B gene to outside databases

Previous GC identifer: GC03M069302


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for FRMD4B Gene:
This gene encodes a GRP1-binding protein which contains a FERM protein interaction domain as well as two coiled
coil domains. This protein may play a role as a scaffolding protein. (provided by RefSeq, Mar 2014)

GeneCards Summary for FRMD4B Gene:
FRMD4B (FERM domain containing 4B) is a protein-coding gene. An important paralog of this gene is MSN.

UniProtKB/Swiss-Prot: FRM4B_HUMAN, Q9Y2L6
Function: Member of GRP1 signaling complexes that are acutely recruited to plasma membrane ruffles in response to
insulin receptor signaling. May function as a scaffolding protein (By similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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Regulatory elements:
   Regulatory transcription factor binding sites in the FRMD4B gene promoter:
         HOXA9   HOXA9B   POU2F1   POU2F1a   Cart-1   Nkx2-5   Tal-1beta   E47   Meis-1   Meis-1b   
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search Chromatin IP Primers for FRMD4B

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat FRMD4B


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 3p14.1   Ensembl cytogenetic band:  3p14.1   HGNC cytogenetic band: 3p14.2

FRMD4B Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
FRMD4B gene location

GeneLoc information about chromosome 3         GeneLoc Exon Structure

GeneLoc location for GC03M069219:  view genomic region     (about GC identifiers)

Start:
69,219,141 bp from pter      End:
69,591,734 bp from pter
Size:
372,594 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: FRM4B_HUMAN, Q9Y2L6 (See protein sequence)
Recommended Name: FERM domain-containing protein 4B  
Size: 1034 amino acids; 118047 Da
Subunit: Interacts with GRP1 (By similarity)
Sequence caution: Sequence=BAA76857.1; Type=Erroneous initiation; Note=Translation N-terminally shortened;
Secondary accessions: Q8TAI3
Alternative splicing: 2 isoforms:  Q9Y2L6-1   Q9Y2L6-2   

Explore the universe of human proteins at neXtProt for FRMD4B: NX_Q9Y2L6

Explore proteomics data for FRMD4B at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See FRMD4B Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_055938.1  
    ENSEMBL proteins: 
     ENSP00000381549   ENSP00000418682   ENSP00000419869   ENSP00000420735   ENSP00000418962  
     ENSP00000418373   ENSP00000418023   ENSP00000417550   ENSP00000417765   ENSP00000437658  

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    Cloud-Clone Corp. Proteins for FRMD4B

     
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    antibodies-online antibodies for FRMD4B (11 products) 

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    antibodies-online kits for FRMD4B (4 products) 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    Selected InterPro protein domains (see all 10):
     IPR019748 FERM_central
     IPR019750 Band_41_fam
     IPR021774 DUF3338
     IPR019747 FERM_CS
     IPR011993 PH_like_dom

    Graphical View of Domain Structure for InterPro Entry Q9Y2L6

    ProtoNet protein and cluster: Q9Y2L6

    1 Blocks protein domain: IPB000299 Band 4.1 domain

    UniProtKB/Swiss-Prot: FRM4B_HUMAN, Q9Y2L6
    Similarity: Contains 1 FERM domain


    Find genes that share domains with FRMD4B           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: FRM4B_HUMAN, Q9Y2L6
    Function: Member of GRP1 signaling complexes that are acutely recruited to plasma membrane ruffles in response to
    insulin receptor signaling. May function as a scaffolding protein (By similarity)

         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding ----
         
    Find genes that share ontologies with FRMD4B           About GenesLikeMe


    Animal Models:
       genOway: Develop your customized and physiologically relevant rodent model for FRMD4B

    miRNA
    Products:
        
    miRTarBase miRNAs that target FRMD4B:
    hsa-mir-9-5p (MIRT021453), hsa-mir-335-5p (MIRT019072), hsa-mir-98-5p (MIRT027864)

    Block miRNA regulation of human, mouse, rat FRMD4B using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate FRMD4B (see all 50):
    hsa-miR-520e hsa-miR-302d hsa-miR-300 hsa-let-7d hsa-miR-429 hsa-miR-106a hsa-miR-192 hsa-let-7g
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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    FRM4B_HUMAN, Q9Y2L6: Cytoplasm, cytoskeleton (By similarity)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytoskeleton2
    cytosol2
    nucleus2
    golgi apparatus1

    Gene Ontology (GO): 4 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0001726ruffle IEA--
    GO:0005615extracellular space IDA--
    GO:0005737cytoplasm IEA--
    GO:0005856cytoskeleton IEA--

    Find genes that share ontologies with FRMD4B           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for FRMD4B
    Interactions:

        Search GeneGlobe Interaction Network for FRMD4B

    STRING Interaction Network Preview (showing 3 interactants - click image to see more details)

    5 Interacting proteins for FRMD4B (Q9Y2L63 ENSP000003815494) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    CYTH3O437393, ENSP000002970444I2D: score=1 STRING: ENSP00000297044
    STAT1P422243I2D: score=2 
    YWHAEP622583I2D: score=1 
    RABEP1ENSP000002624774STRING: ENSP00000262477
    USO1ENSP000004116984STRING: ENSP00000411698
    About this table

    Gene Ontology (GO): 1 biological process term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0090162establishment of epithelial cell polarity IEA--

    Find genes that share ontologies with FRMD4B           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for FRMD4B (FRM4B)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for FRMD4B gene: 
    NM_015123.2  

    Selected Ensembl transcripts including schematic representations, and UCSC links where relevant (see all 19):
    ENST00000398540(uc003dnu.2 uc011bga.1 uc003dnw.2) ENST00000478263
    ENST00000462512 ENST00000497475 ENST00000489817 ENST00000470070(uc003dnx.1)
    ENST00000483668 ENST00000487751 ENST00000493880 ENST00000473029 ENST00000460709
    ENST00000473188(uc003dny.3) ENST00000459638 ENST00000462308 ENST00000497880
    ENST00000497757 ENST00000493127 ENST00000462888
    miRNA
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    Block miRNA regulation of human, mouse, rat FRMD4B using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate FRMD4B (see all 50):
    hsa-miR-520e hsa-miR-302d hsa-miR-300 hsa-let-7d hsa-miR-429 hsa-miR-106a hsa-miR-192 hsa-let-7g
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      QuantiTect SYBR Green Assays in human, mouse, rat FRMD4B
      QuantiFast Probe-based Assays in human, mouse, rat FRMD4B

    Selected AceView cDNA sequences (see all 123):

    AV649269 AK024086 BX279831 AU118463 AV728703 BC028291 BU753321 AL601610 
    AW471301 AB023230 BU858632 BM719674 BU679763 AA234921 AI590884 AA341871 
    AK091076 AV728917 BQ003851 CA444552 AA234920 CB988073 AW675370 AI658773 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for FRMD4B (see all 6)    About this scheme

    ExUns: 1a · 1b · 1c ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12 ^ 13 ^ 14 ^ 15 ^ 16 ^ 17 ^ 18 ^ 19 ^ 20 ^ 21a · 21b ^ 22 ^ 23
    SP1:                                                                                                                                                            
    SP2:                    -     -     -     -                 -                                                                                                   
    SP3:                                                                                                                                                            
    SP4:                    -                                                                                                                                       
    SP5:                                                                                                                                                            


    ECgene alternative splicing isoforms for FRMD4B

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    FRMD4B expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TAATATATAC
    FRMD4B Expression
    About this image


    FRMD4B expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 7) fully expand
     
     Eye (Sensory Organs)    fully expand to see all 3 entries
             nGnG Amacrine Cells Inner Nuclear Layer
             Retina
     
     Neurons
             nGnG Amacrine Cells Inner Nuclear Layer
     
     Blood (Cardiovascular System)    fully expand to see all 2 entries
             Natural Killer Cells Peripheral Blood
     
     Spleen (Hematopoietic System)
             Conventional Dendritic Cells I Spleen
     
     Liver (Hepatobiliary System)
             Periportal Hepatocytes Liver Lobule
    FRMD4B Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    FRMD4B Protein Expression
        Custom PCR Arrays for FRMD4B
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FRMD4B

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for FRMD4B gene from Selected species (see all 13)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Frmd4b1 , 5 FERM domain containing 4B1, 5 86.73(n)1
    93.47(a)1
      6 (44.93 cM)5
    2322881  NM_145148.21  NP_660130.21 
     972868675 
    chicken
    (Gallus gallus)
    Aves FRMD4B1 FERM domain containing 4B 76.49(n)
    83.24(a)
      426071  XM_423748.4  XP_423748.2 
    lizard
    (Anolis carolinensis)
    Reptilia FRMD4B6
    FERM domain containing 4B
    81(a)
    1 ↔ 1
    2(182067972-182253464)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia Str.20282 Transcribed sequence with weak similarity to protein more 76(n)    CF523470.1 
    zebrafish
    (Danio rerio)
    Actinopterygii frmd4bb1 FERM domain containing 4Bb 60.78(n)
    59.59(a)
      100329900  XM_002666394.3  XP_002666440.2 
    worm
    (Caenorhabditis elegans)
    Secernentea F07C6.46
    Protein F07C6.4, isoform e (M02B1.4) mRNA, complet...
    19(a)
    1 → many
    IV(12805931-12830109) WBGene00008555


    ENSEMBL Gene Tree for FRMD4B (if available)
    TreeFam Gene Tree for FRMD4B (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for FRMD4B gene
    MSN2  MYLIP2  FRMD4A2  NF22  RDX2  EZR2  C1orf1062  
    11 SIMAP similar genes for FRMD4B using alignment to 12 protein entries:     FRM4B_HUMAN (see all proteins):
    FRMD4A    RDX    EZR-ROS1    PTPN14    PTPN21    FRMD5
    MSN    EZR    FARP1    PTPN4    VIL2

    Find genes that share paralogs with FRMD4B           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for FRMD4B (see all 5200)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 3 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs58498801,2
    C--69197406(+) AAGTA-/AGCA  
            
    AGCAA
    1 -- int10--------
    rs124945411,2
    C,A,H--69218696(+) AGAGAC/TGGGGT 1 -- ds50018Minor allele frequency- T:0.07NA WA CSA 15
    rs1823212121,2
    --69218715(+) GTTGTC/TCAGGC 1 -- ds50010--------
    rs1873850991,2
    --69218719(+) TCCAGG/TCTGGT 1 -- ds50010--------
    rs1117912391,2
    C--69218760(+) ACTTCA/GGCCTC 1 -- ds50010--------
    rs1467947931,2
    --69218763(+) TCGGCC/TTCCCA 1 -- ds50010--------
    rs1405828961,2
    --69219009(+) TAATTC/TCTTGA 1 -- ds50010--------
    rs67651971,2
    C,F,A,H--69219110(+) TCTCAT/CCAGTC 1 -- ds500120Minor allele frequency- C:0.22NS EA NA WA CSA 931
    rs1457051691,2
    --69219161(+) GGCAAA/CTTTAT 1 -- ut310--------
    rs67653091,2
    C,A,H--69219251(+) TGAACT/CATGTT 1 -- ut318Minor allele frequency- C:0.30NA WA EA 368

    HapMap Linkage Disequilibrium report for FRMD4B (69219141 - 69469141 bp, first 250kb of FRMD4B)

    Structural Variations
         Database of Genomic Variants (DGV) Selected variations for FRMD4B (see all 19):    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2725390CNV Deletion23290073
    esv2725387CNV Deletion23290073
    esv2725388CNV Deletion23290073
    esv1002559CNV Deletion20482838
    esv2725389CNV Deletion23290073
    esv2725384CNV Deletion23290073
    esv1946491CNV Deletion18987734
    esv2725386CNV Deletion23290073
    esv2675880CNV Deletion23128226
    esv1435155CNV Deletion17803354

    Site Specific Mutation Identification with PCR Assays
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    Find genes that share disorders with FRMD4B           About GenesLikeMe

    Genetic Association Database (GAD): FRMD4B
    Human Genome Epidemiology (HuGE) Navigator: FRMD4B (5 documents)

    Export disorders for FRMD4B gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for FRMD4B gene, integrated from 10 sources (see all 15):
    (articles sorted by number of sources associating them with FRMD4B)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Prediction of the coding sequences of unidentified human genes. XIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 10231032)1, 2, 3 Nagase T.... Ohara O. (DNA Res. 1999)
    2. Signaling complexes of the FERM domain-containing protein GRSP1 bound to ARF exchange factor GRP1. (PubMed id 11445584)1, 3, 9 Klarlund J.K....Czech M.P. (J. Biol. Chem. 2001)
    3. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (Mol. Med. 2010)
    4. Association of an intronic, but not any exonic, FRMD4B sequence variant and heart failure. (PubMed id 20718813)1, 4 Matkovich S.J....Dorn G.W. (Clin Transl Sci 2010)
    5. Multiple common variants for celiac disease influencing immune gene expression. (PubMed id 20190752)1, 4 Dubois P.C....van Heel D.A. (Nat. Genet. 2010)
    6. Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. (PubMed id 20628086)1, 4 Bailey S.D....Anand S. (Diabetes Care 2010)
    7. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    8. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    9. Common variants in HSPB7 and FRMD4B associated with advanced heart failure. (PubMed id 20124441)1 Cappola T.P....Dorn G.W. (Circ Cardiovasc Genet 2010)
    10. Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip. (PubMed id 19913121)1 Talmud P.J.... . (Am. J. Hum. Genet. 2009)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 23150 HGNC: 24886 AceView: FRMD4B Ensembl:ENSG00000114541 euGenes: HUgn23150
    ECgene: FRMD4B H-InvDB: FRMD4B

    (According to HUGE)
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    HUGE: KIAA1013

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for FRMD4B Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for FRMD4B gene:
    Search GeneIP for patents involving FRMD4B

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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