Aliases for FRMD4B Gene
External Ids for FRMD4B Gene
Previous GeneCards Identifiers for FRMD4B Gene
This gene encodes a GRP1-binding protein which contains a FERM protein interaction domain as well as two coiled coil domains. This protein may play a role as a scaffolding protein. [provided by RefSeq, Mar 2014]
GeneCards Summary for FRMD4B Gene
FRMD4B (FERM Domain Containing 4B) is a Protein Coding gene. An important paralog of this gene is FRMD4A.
UniProtKB/Swiss-Prot for FRMD4B Gene
Member of GRP1 signaling complexes that are acutely recruited to plasma membrane ruffles in response to insulin receptor signaling. May function as a scaffolding protein that regulates epithelial cell polarity by connecting ARF6 activation with the PAR3 complex. Plays a redundant role with FRMD4A in epithelial polarization.