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Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

FRMD3 Gene

protein-coding GIFtS: 45
GCID: GC09M085857

FERM domain containing 3

Explore 2 diseases affiliated with
FRMD3 via

MalaCards

our new
Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

Aliases
FERM Domain Containing 3¹ ²		MGC20553¹
EPB41L4O¹ ² ³		P410²
Band 4.1-Like Protein 4O² ³		Band 4.1-Like Protein 4²
Ovary Type Protein 4.1² ³		FERM Domain-Containing Protein 3²
4.1O² ³		Protein 4.1O²
EPB41LO² ⁵

External Ids:	HGNC: 24125¹	Entrez Gene: 257019²	Ensembl: ENSG00000172159⁷	OMIM: 607619⁵	UniProtKB: A2A2Y4³

Export aliases for FRMD3 gene to outside databases

Previous GC identifers: GC09M081315 GC09M083087 GC09M085047 GC09M055687

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for FRMD3:

The protein encoded by this gene is a single pass membrane protein primarily found in ovaries. A similar protein in

erythrocytes helps determine the shape of red blood cells, but the function of the encoded protein has not been

determined. There is some evidence that this is a tumor suppressor gene, and there is also evidence linking defects in

this gene to susceptibility to diabetic nephropathy in type 1 diabetes. Several transcript variants encoding different

isoforms have been found for this gene. (provided by RefSeq, Oct 2011)

UniProtKB/Swiss-Prot: FRMD3_HUMAN, A2A2Y4

Function: Putative tumor suppressor gene that may be implicated in the origin and progression of lung cancer

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000009.11 NC_018920.1 NT_008470.19

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the FRMD3 gene promoter:
USF1 Spz1 ATF-2 CREB CRE-BP1 HEN1 E2F-1 E2F USF-1 ZID
Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: FRMD3 promoter sequence

Search SABiosciences Chromatin IP Primers for FRMD3

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat FRMD3

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 9q21.32 Ensembl cytogenetic band: 9q21.32 HGNC cytogenetic band: 9q21.33

FRMD3 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
FRMD3 gene location

GeneLoc information about chromosome 9 GeneLoc Exon Structure

GeneLoc location for GC09M085857: view genomic region (about GC identifiers)

Start:	85,857,905 bp from pter	End:	86,153,461 bp from pter
Size:	295,557 bases	Orientation:	minus strand

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: FRMD3_HUMAN, A2A2Y4 (See protein sequence)

Recommended Name: FERM domain-containing protein 3

Size: 597 amino acids; 68772 Da

Subcellular location: Membrane; Single-pass membrane protein (Potential)

Developmental stage: Expressed in skeletal muscle, lower levels in thymus and brain

Sequence caution: Sequence=BAC04321.1; Type=Erroneous initiation; Sequence=EAW62650.1; Type=Erroneous initiation;

Secondary accessions: A8MQB0 B4DN14 Q53EP2 Q5JV59 Q5VZA1 Q86WP8 Q8IZ44 Q8N3Y5 Q8N9L2

Alternative splicing: 5 isoforms: A2A2Y4-1 A2A2Y4-2 A2A2Y4-3 A2A2Y4-4 A2A2Y4-5 (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for FRMD3: NX_A2A2Y4

Post-translational modifications:

View modification sites using PhosphoSitePlus²

View neXtProt modification sites for NX_A2A2Y4

FRMD3 Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins (5 alternative transcripts):

NP_001231888.1 NP_001231889.1 NP_001231890.1 NP_001231891.1 NP_777598.3

ENSEMBL proteins:

ENSP00000365621 ENSP00000365617 ENSP00000328615 ENSP00000303508 ENSP00000412719

Human Recombinant Protein Products:

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	Uscn Proteins for FRMD3

Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005737	cytoplasm	IEA	--
GO:0005856	cytoskeleton	IEA	--
GO:0016021	integral to membrane	IEA	--
GO:0019898	extrinsic to membrane	IEA	--

FRMD3 for ontologies About GeneDecksing

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	Uscn ELISAs and CLIAs for FRMD3

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

FRMD3 for domains About GeneDecksing

5/11 InterPro domains/families (see all 11):

IPR019748 FERM_central

IPR019750 Band_41_fam

IPR000798 Ez/rad/moesin

IPR019747 FERM_CS

IPR011993 PH_like_dom

Graphical View of Domain Structure for InterPro Entry A2A2Y4

ProtoNet protein and cluster: A2A2Y4

UniProtKB/Swiss-Prot: FRMD3_HUMAN, A2A2Y4

Similarity: Contains 1 FERM domain

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

Function Summary:

UniProtKB/Swiss-Prot: FRMD3_HUMAN, A2A2Y4

Function: Putative tumor suppressor gene that may be implicated in the origin and progression of lung cancer

miRNA Products:		OriGene 3'-UTR Clone: FRMD3 Browse MicroRNA Expression Plasmids
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		6 QIAGEN miScript miRNA Assays for microRNAs that regulate FRMD3:
		hsa-miR-3651 hsa-miR-129-3p hsa-miR-938 hsa-miR-129* hsa-miR-548c-3p hsa-miR-1256
		SwitchGear 3'UTR luciferase reporter plasmid: FRMD3 3' UTR sequence

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Gene Editing
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In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FRMD3

Gene Ontology (GO): 1 molecular function term (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0008092	cytoskeletal protein binding	IEA	--

FRMD3 for ontologies About GeneDecksing

1 GenomeRNAi human phenotype for FRMD3:

Increased TP53 protein express

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Interactions:

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for FRMD3

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for FRMD3
Search CenterWatch for drugs/clinical trials and news about FRMD3

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for FRMD3 gene (5 alternative transcripts):

NM_001244959.1 NM_001244960.1 NM_001244961.1 NM_001244962.1 NM_174938.5

Unigene Clusters for FRMD3:

FERM domain containing 3

Hs.127535 [show with all ESTs], Hs.743606 [show with all ESTs]

Unigene Representative Sequences: NM_174938, BC023560

6 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000376438(uc004amr.1) ENST00000376434(uc022biz.1) ENST00000328788(uc004amq.1)

ENST00000304195(uc022bja.1 uc004ams.2) ENST00000465485 ENST00000431299

miRNA Products:		OriGene 3'-UTR Clone: FRMD3 Browse OriGene MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat FRMD3
		6 QIAGEN miScript miRNA Assays for microRNAs that regulate FRMD3:
		hsa-miR-3651 hsa-miR-129-3p hsa-miR-938 hsa-miR-129* hsa-miR-548c-3p hsa-miR-1256
		SwitchGear 3'UTR luciferase reporter plasmid: FRMD3 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for FRMD3 (see all 6) OriGene shRNA RFP: FRMD3 OriGene siRNA: FRMD3
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat FRMD3

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		GenScript: all cDNA clones in your preferred vector: FRMD3 (NM_174938)
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		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FRMD3

Primer Products:		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for FRMD3 Browse OriGene validated miRNA SYBR primer pairs
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Additional cDNA sequence: BC023560.1

8 DOTS entries:

DT.99996872 DT.75180596 DT.433205 DT.100018807 DT.100018809 DT.121144399 DT.97837252 DT.75104450

24/83 AceView cDNA sequences (see all 83):

BM666832 BX089823 BM873990 AI984360 BM715647 BM874423 AA402220 BU189443

BF110588 BE221726 W32094 BI827685 BM674088 BC023560 AW162166 BC037253

AK094281 AI015267 AI624361 BU618212 AI540628 AW160536 BX390381 AI492565

GeneLoc Exon Structure

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

FRMD3 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TTACATTGGA

About this image

FRMD3 expression in embryonic tissues and stem cells

Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine About this table

1 LifeMap In Vivo Development Anatomical Compartment/Cell

Tissue

Anatomical Compartment

Cell

Category (developmental path)

Eye

Inner Nuclear Layer

Mature Rod Bipolar Cells

Bipolar, Retina

Expression:

Positive

Negative

Selective marker

Experimental details:

Curated

Microarrays

In-situ hybridization

Stem Cell Differentiation: 1 LifeMap Cell

Name

Category

PureStem™ endothelial progenitor 30-MV2-14 (Embryonic Progenitor Cell)

Endothelium

See FRMD3 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for FRMD3

SOURCE GeneReport for Unigene clusters: Hs.127535 Hs.743606

UniProtKB/Swiss-Prot: FRMD3_HUMAN, A2A2Y4

Tissue specificity: Ovary-specific

SABiosciences Custom PCR Arrays for FRMD3

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		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat FRMD3

In Situ
Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FRMD3

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of animals.

Orthologs for FRMD3 gene from 5/17 species (see all 17) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
chicken (Gallus gallus)	Aves	FRMD3¹	FERM domain containing 3	81.05(n) 84.58(a)		427452 XM_003643038.1 XP_003643086.1
lizard (Anolis carolinensis)	Reptilia	FRMD3⁶	--	80(a)	1 ↔ 1	2(42809720-42879825)
zebrafish (Danio rerio)	Actinopterygii	LOC100331256¹	erythrocyte protein band 4.1-like 1-like	65.81(n) 64.73(a)		100331256 XM_002663231.1 XP_002663277.1
fruit fly (Drosophila melanogaster)	Insecta	CG5022¹	CG5022	48.5(n) 41.85(a)		34398 NM_135540.1 NP_609384.1
worm (Caenorhabditis elegans)	Secernentea	frm-4⁶	FERM domain (protein4.1-ezrin-radixin-moesin) fami...	19(a)	1 → many	I(5402898-5408462)

ENSEMBL Gene Tree for FRMD3 (if available)
TreeFam Gene Tree for FRMD3 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for FRMD3 gene

EPB41² EPB41L5² EPB41L1² EPB41L4B² FARP1² FRMD5² MYLIP² EPB41L3²

FRMD7² EPB41L4A² FARP2² EPB41L2²

11 SIMAP similar genes for FRMD3 using alignment to 2 protein entries: FRMD3_HUMAN (see all proteins):

FRMD5 EPB41L1 PTPN4 EPB41 EPB41L4A EPB41L4B

EPB41L2 EPB41L5 EPB41L3 FARP2 FARP1

FRMD3 for paralogs About GeneDecksing

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 9 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs186386217^1,2		--	85857429(+)	`GTCTCC/TGTGGA`	3	--	ds500¹		0	--	--	--	--
rs141231463^1,2		--	85857517(+)	`ATTTGC/TAAGCC`	3	--	ds500¹		0	--	--	--	--
rs7046038^1,2	C,F,H,	--	85857590(+)	`AACATT/GGAAAA`	3	--	ds500¹		4		NS EA	418
rs146975987^1,2		--	85857684(+)	`CTTCTA/GTTCTT`	3	--	ds500¹		0	--	--	--	--
rs7857822^1,2	C,F,A,H,	--	85857703(+)	`ATAACG/AGATAA`	3	--	ds500¹		5		NS EA WA	536
rs144173194^1,2		--	85857712(+)	`AAGCTC/GTCTCA`	3	--	ds500¹		0	--	--	--	--
rs7030534^1,2	C,H	--	85857971(+)	`GCAAGG/TTTCCT`	3	--	ut3¹ ese³		3		NS EA	298
rs58353229^1,2	F,	--	85858003(+)	`GCTGCC/TGAGCC`	3	--	ut3¹		1		WA	118
rs73648518^1,2	C,	--	85858026(+)	`CCCACC/TGAACT`	3	--	ut3¹		2		WA	120
rs150174690^1,2		--	85858201(+)	`AGTAAA/GCAGCG`	3	--	int¹		0	--	--	--	--

HapMap Linkage Disequilibrium report for FRMD3 (85857905 - 86107905 bp, first 250kb of FRMD3)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for FRMD3: --

SABiosciences Cancer Mutation PCR Assays

QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing FRMD3

DNA2.0 Custom Variant and Variant Library Synthesis for FRMD3

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

FRMD3 for disorders           About GeneDecksing

OMIM gene information: 607619    OMIM disorders: --

2 diseases for FRMD3:    About MalaCards

nephropathy lung cancer

Human Genome Epidemiology (HuGE) Navigator: FRMD3 (5 documents)

Export disorders for FRMD3 gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
About This Section

PubMed articles for FRMD3 gene, integrated from 9 sources (see all 12):
(articles sorted by number of sources associating them with FRMD3)

Utopia: connect your pdf to the dynamic
world of online information

Molecular cloning and characterization of the protein 4.1O gene, a novel member of the protein 4.1 family with focal expression in ovary. (PubMed id 12601556)^{1, 2, 3, 9} Ni X....Mao Y. (2003)
FRMD3, a novel putative tumour suppressor in NSCLC. (PubMed id 17260017)^{1, 2} Haase D.... Angel P. (2007)
Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)^{1, 2} Ota T.... Sugano S. (2004)
Differential effects of MYH9 and APOL1 risk variants on FRMD3 Association with Diabetic ESRD in African Americans. (PubMed id 21698141)¹ Freedman B.I....Bowden D.W. (2011)
Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)¹ Rose J.E....Uhl G.R. (2010)
Replication study for the association between four Lo ci identified by a genome-wide association study on European american subjects with type 1 diabetes and susceptibility to diabetic nephropathy in Japanese sub jects with type 2 diabetes. (PubMed id 20460425)¹ Maeda S....Nakamura Y. (2010)
Genome-wide association scan for diabetic nephropathy susceptibility genes in type 1 diabetes. (PubMed id 19252134)¹ Pezzolesi M.G....Krolewski A.S. (2009)
The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005)² Bechtel S.... Schupp I. (2007)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)² Gerhard D.S....Malek J. (2004)
DNA sequence and analysis of human chromosome 9. (PubMed id 15164053)² Humphray S.J.... Dunham I. (2004)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section

Entrez Gene: 257019	HGNC: 24125	AceView: FRMD3	Ensembl:ENSG00000172159	euGenes: HUgn257019
ECgene: FRMD3	H-InvDB: FRMD3

(According to HUGE)
About This Section

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
PharmGKB entry for FRMD3	Pharmacogenomics, SNPs, Pathways

Intellectual Property for FRMD3 gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

About This Section

Patent Information for FRMD3 gene:
Search GeneIP for patents involving FRMD3

GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search

(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences),
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	Browse OriGene Antibodies		OriGene shRNA RFP for FRMD3
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Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FRMD3

GeneCards Homepage - Last full update: 19 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 26 Apr 2013

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Category			VWF (GIFTS: 73) von Willebrand factor
GIFtS Group

The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

The GeneCards Human Gene Database

Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

Hot genes Disease genes FRMD3 gene at Home site.

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FRMD3 Gene

FERM domain containing 3

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FRMD3 Gene

FERM domain containing 3

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Protein Domains /Familiesfor FRMD3 gene

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