Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 
or upload a file of gene symbols


Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

FRG2 Gene

protein-coding   GIFtS: 39
GCID: GC04M190945

FSHD Region Gene 2

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
FSHD Region Gene 21 2
FRG2A2 3
FSHD Region Gene 2 Protein2 3
Protein FRG22

External Ids:    HGNC: 191361   Entrez Gene: 4488312   Ensembl: ENSG000002050977   OMIM: 6090325   UniProtKB: Q64ET83   

Export aliases for FRG2 gene to outside databases

Previous GC identifers: GC10M135327 GC04U900480 GC04M191182


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for FRG2 Gene: 
FRG2 (FSHD region gene 2) is a protein-coding gene. Diseases associated with FRG2 include facioscapulohumeral muscular dystrophy, and muscular dystrophy. An important paralog of this gene is LOC651959.


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000004.11  NT_016354.19  NC_018915.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the FRG2 gene promoter:
         TBP   SREBP-1a   AML1a   SREBP-1c   SEF-1 (1)   POU6F1 (c2)   SREBP-1b   C/EBPalpha   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidFRG2 promoter sequence
   Search SABiosciences Chromatin IP Primers for FRG2

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat FRG2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 4q35   Ensembl cytogenetic band:  4q35.2   HGNC cytogenetic band: 4q35.2

FRG2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
FRG2 gene location

GeneLoc information about chromosome 4         GeneLoc Exon Structure

GeneLoc location for GC04M190945:  view genomic region     (about GC identifiers)

Start:
190,945,506 bp from pter      End:
190,948,412 bp from pter
Size:
2,907 bases      Orientation:
minus strand

1 alternative location:
Chr4-,NW_003571034 117,297-120,187     

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: FRG2_HUMAN, Q64ET8 (See protein sequence)
Recommended Name: Protein FRG2  
Size: 278 amino acids; 30490 Da
Subcellular location: Nucleus

Explore the universe of human proteins at neXtProt for FRG2: NX_Q64ET8

Explore proteomics data for FRG2 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q64ET8

  • FRG2 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    FRG2 Protein Expression
    REFSEQ proteins: NP_001005217.1  
    ENSEMBL proteins: 
     ENSP00000424015   ENSP00000368039  

    Human Recombinant Protein Products for FRG2: 
    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    OriGene Purified Protein for FRG2
    OriGene Protein Over-expression Lysate for FRG2
    OriGene MassSpec for FRG2 
    OriGene Custom Protein Services for FRG2
    GenScript Custom Purified and Recombinant Proteins Services for FRG2
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for FRG2 

    Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IEA--

    FRG2 for ontologies           About GeneDecksing



    FRG2 Antibody Products: 
    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    Browse OriGene Antibodies
    OriGene Custom Antibody Services for FRG2
    GenScript Custom Superior Antibodies Services for FRG2
    Search for Antibodies for FRG2 at Abcam
    Cloud-Clone Corp. Antibodies for FRG2 
    Search ThermoFisher Antibodies for FRG2
    LSBio Antibodies in human, mouse, rat for FRG2 

    Assay Products for FRG2: 
    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for FRG2
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for FRG2
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for FRG2 
    Cloud-Clone Corp. CLIAs for FRG2


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    1 InterPro protein domain:
     IPR026245 FRG2

    Graphical View of Domain Structure for InterPro Entry Q64ET8

    ProtoNet protein and cluster: Q64ET8

    UniProtKB/Swiss-Prot: FRG2_HUMAN, Q64ET8
    Similarity: Belongs to the FRG2 family


    FRG2 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for FRG2 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for FRG2

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for FRG2 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for FRG2 

    miRNA
    Products:
        
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat FRG2
    Search QIAGEN for miScript miRNA Assays for microRNAs that regulate FRG2
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:
        
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for FRG2
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat FRG2

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for FRG2
    Sirion Biotech Customized adenovirus for overexpression of FRG2

    Clone
    Products:
         
    Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
    OriGene clones in human, mouse for FRG2 (see all 5)
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: FRG2 (NM_001080998)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for FRG2
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FRG2
    Sirion Biotech Customized lentivirus for stable overexpression of FRG2 
                         Customized lentivirus expression plasmids for stable overexpression of FRG2 

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for FRG2
    Search LifeMap BioReagents cell lines for FRG2
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FRG2


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for FRG2

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for FRG2

    Search CenterWatch for drugs/clinical trials and news about FRG2

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for FRG2 gene: 
    NM_001005217.1  

    Unigene Cluster for FRG2:

    FSHD region gene 2
    Hs.626907
    Unigene Representative Sequence: AY714545
    2 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000504750 ENST00000378763(uc003izv.3 uc011clh.2)
    miRNA
    Products:
         
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat FRG2
    Search QIAGEN for miScript miRNA Assays for microRNAs that regulate FRG2
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for FRG2
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat FRG2
    Clone
    Products:
         
    OriGene clones in human, mouse for FRG2 (see all 5)
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: FRG2 (NM_001080998)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for FRG2
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FRG2
    Sirion Biotech Customized lentivirus for stable overexpression of FRG2 
                         Customized lentivirus expression plasmids for stable overexpression of FRG2 
    Primer
    Products:
        
    OriGene qSTAR qPCR primer pairs in human, mouse for FRG2
    Search SABiosciences RT2 qPCR Primer Assays in human, mouse, rat FRG2
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat FRG2
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat FRG2

    Additional mRNA sequence: 

    AY714545.1 BC144572.1 

    1 DOTS entry:

    DT.40273603 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    FRG2 expression in normal human tissues (normalized intensities)      FRG2 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TTTCATTTCA
    FRG2 Expression
    About this image


    FRG2 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/2 selected tissues (see all 2) fully expand
     
     Smooth Muscle (Muscoskeletal System)
             Juxtaglomerular Cells Afferent Arteriole
     
     Kidney (Urinary System)
             Juxtaglomerular Cells Afferent Arteriole

    See FRG2 Protein Expression from SPIRE MOPED and PaxDB
    SOURCE GeneReport for Unigene cluster: Hs.626907

    UniProtKB/Swiss-Prot: FRG2_HUMAN, Q64ET8
    Tissue specificity: Expression is undetectable in all tissues tested except for differentiating myoblasts of FSHD
    patients, which display low, yet distinct levels of expression, partly from FRG2, but predominantly originating
    from its homolog on chromosome 10

        SABiosciences Custom PCR Arrays for FRG2
    Primer
    Products:
    OriGene qSTAR qPCR primer pairs in human, mouse for FRG2
    Search SABiosciences RT2 qPCR Primer Assays in human, mouse, rat FRG2
    QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat FRG2
    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat FRG2
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FRG2

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of human and mouse.

    Orthologs for FRG2 gene from 1/5 species (see all 5)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Gm62195
    Gm62801
    predicted gene 62195
    predicted gene 62801
    53.96(n)1
    43.09(a)1
      14 (56.16 cM)5
    6220521  XM_886462.11  XP_891555.11 
     1060931505 


    ENSEMBL Gene Tree for FRG2 (if available)
    TreeFam Gene Tree for FRG2 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for FRG2 gene
    LOC100288255  FRG2B1 2  LOC6519592  ENSG000001488282  FRG2C2  
    2 SIMAP similar genes for FRG2 using alignment to 3 protein entries:     FRG2_HUMAN (see all proteins):
    FRG2B    FRG2C

    FRG2 for paralogs           About GeneDecksing


    2 Pseudogenes.org Pseudogenes for FRG2
    PGOHUM00000239034 PGOHUM00000238321


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/31 SNPs in FRG2 are shown (see all 31)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 4 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1435851191,2
    C--190947544(+) CTGCTC/GTGTCT 2 T R mis10--------
    rs1996158251,2
    C,F--190947629(+) CACAAT/AGAGAG 1 -- int11Minor allele frequency- A:0.00EU 809
    rs2008170711,2
    C--190949302(+) CTGCCG/TCAGTG 1 -- us2k10--------
    rs2015073441,2
    ----190949890(+) ACTGCG/TTTTTG 1 -- us2k10--------
    rs3746732891,2
    ----190949036(+) AGTCTA/CGTGGA 1 -- us2k10--------
    rs3771189371,2
    ----190947808(+) TTGCTG/TCCTGT 1 -- int10--------
    rs3746592801,2
    ----190949641(+) GGAACC/GAAAAA 1 -- us2k10--------
    rs3713361711,2
    ----190949571(+) GAAAGA/TACAGG 1 -- us2k10--------
    rs2017495011,2
    ----190947570(+) GAACTC/GATTTT 2 I M mis10--------
    rs3685489531,2
    ----190949056(+) CCCCCA/TTCTCA 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for FRG2 (190945506 - 190948412 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 9 variations for FRG2:    About this table     
    Variant IDTypeSubtypePubMed ID
    nsv471487CNV Duplication19718026
    nsv513204CNV Loss21212237
    dgv5873n71CNV Loss21882294
    nsv10641CNV Loss18304495
    dgv5875n71CNV Gain21882294
    nsv880818CNV Gain21882294
    nsv880553CNV Gain21882294
    nsv482089CNV Gain20164927
    esv23426CNV Gain+Loss19812545

    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing FRG2
    DNA2.0 Custom Variant and Variant Library Synthesis for FRG2

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 609032    OMIM disorders: --

    2 diseases for FRG2:    About MalaCards
    facioscapulohumeral muscular dystrophy    muscular dystrophy

    1 disease from the University of Copenhagen DISEASES database for FRG2:
    Facioscapulohumeral muscular dystrophy

    FRG2 for disorders           About GeneDecksing


    Export disorders for FRG2 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for FRG2 gene, integrated from 9 sources (see all 12):
    (articles sorted by number of sources associating them with FRG2)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. FRG2, an FSHD candidate gene, is transcriptionally upregulated in differentiating primary myoblast cultures of FSHD patients. (PubMed id 15520407)1, 2, 3, 9 Rijkers T....van der Maarel S.M. (2004)
    2. Inappropriate gene activation in FSHD: a repressor complex binds a chromosomal repeat deleted in dystrophic muscle. (PubMed id 12176321)1, 3 Gabellini D....Tupler R. (2002)
    3. Expression profiling of FSHD-1 and FSHD-2 cells durin g myogenic differentiation evidences common and distinctive gene dysregulation patterns. (PubMed id 21695143)1 Cheli S....Meneveri R. (2011)
    4. Clinical features of facioscapulohumeral muscular dys trophy 2. (PubMed id 20975055)1 de Greef J.C....Tawil R. (2010)
    5. Genomic analysis of human chromosome 10q and 4q telomeres suggests a common origin. (PubMed id 11829491)1 van Geel M.... Hewitt J.E. (2002)
    6. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
    7. Analysis of allele-specific RNA transcription in FSHD by RNA-DNA FISH in single myonuclei. (PubMed id 19888305)9 Masny P.S....Winokur S.T. (2010)
    8. Comprehensive expression analysis of FSHD candidate g enes at the mRNA and protein level. (PubMed id 19809486)9 Klooster R....van der Maarel S. (2009)
    9. Facioscapulohumeral muscular dystrophy in mice overexpressing FRG1. (PubMed id 16341202)9 Gabellini D....Tupler R. (2006)
    10. Remodeling of the chromatin structure of the faciosca pulohumeral muscular dystrophy (FSHD) locus and upregulation of FSHD-related ge ne 1 (FRG1) expression during human myogenic differentiation. (PubMed id 19607661)9 Bodega B....Ginelli E. (2009)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 448831 HGNC: 19136 Ensembl:ENSG00000205097 euGenes: HUgn448831 ECgene: FRG2
    H-InvDB: FRG2

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for FRG2 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for FRG2 gene:
    Search GeneIP for patents involving FRG2

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

     
     EMD Millipore Custom Antibody & Bulk Services
     EMD Millipore Preclinical / Clinical Development Services
     EMD Millipore Immunoassay Services
     EMD Millipore Target Screening & Profiling Services

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Kinase Activity Assays/Reagents  
     Browse ELISpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Multiplex/Array Assay Kits/Reagents  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Protease Activity Assays and Reagents   Browse Recombinant/Natural Proteins  
     Browse Stem Cell Products   Browse Tocris Biochemicals & Compounds  
     Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
     Browse OriGene Antibodies   OriGene RNAi products in human, mouse, rat for FRG2  
     Browse OriGene qPCR primer pairs and template standards   OriGene Protein Over-expression Lysate for FRG2  
     OriGene MassSpec something-or-other for FRG2   OriGene clones in human, mouse for FRG2  
     OriGene qSTAR qPCR primer pairs in human, mouse for FRG2   OriGene Purified Protein for FRG2  
     Browse OriGene ORF clones   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for FRG2   OriGene Custom Protein Services for FRG2  

     
     
     QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat FRG2
     QIAGEN SeqTarget long-range PCR primers for resequencing FRG2
     QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat FRG2
     QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat FRG2
     QIAGEN QuantiFast Probe-based Assays in human, mouse, rat FRG2
     QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat FRG2
     GenScript Custom Purified and Recombinant Proteins Services for FRG2 GenScript cDNA clones with any tag delivered in your preferred vector for FRG2
     GenScript Custom Assay Services for FRG2 GenScript Custom Superior Antibodies Services for FRG2
     GenScript Custom overexpressing Cell Line Services for FRG2 CloneReady with Over 120,000 Genes
     Gene Synthesis: Any Gene in Any Vector Vector-based siRNA and miRNA, Ready for Transfection
     Gene Mutant Library, Variants up to 10^11 Plasmid Preparation
     Custom Peptide Services
     Search for Antibodies & Assays

     Regulatory tfbs in FRG2 promoter
     Search Chromatin IP Primers for FRG2
     Search RT2 qPCR Primer Assays in human, mouse, rat FRG2
     Search GNC Networks for FRG2
     SABiosciences Custom PCR Arrays for FRG2
     Search Tocris compounds for FRG2
     Browse Sino Biological Proteins and Antibodies
     Browse Sino Biological Cell Lysates
     Browse Sino Biological cDNA Clones
     4000+ Proteins
     Search Sino Biological for antibodies, proteins & pathways
     Protein Production Services
     Transfection Reagents
     Protein A/G/L resins
     Isotyping reagents
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies
     Novus Biologicals
     Novus Tissue Slides
     Search for Antibodies for FRG2 at Abcam
     See all of Abcam's Antibodies, Kits and Proteins for FRG2
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins




     Proteins for FRG2
     Antibodies for FRG2
     ELISAs for FRG2
     CLIAs for FRG2
     Search LifeMap BioReagents cell lines for FRG2
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FRG2
     Browse SwitchGear 3'UTR luciferase reporter plasmids for FRG2
     SwitchGear Promoter luciferase reporter plasmids for FRG2
     Search ThermoFisher Antibodies for FRG2
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FRG2
     inGenious Targeting Laboratory - Custom generated mouse model solutions for FRG2
     inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for FRG2
    Customized:
     lentivirus for stable overexpression of FRG2
     lentivirus expression plasmids for stable overexpression of FRG2
     adenovirus for overexpression of FRG2
     LSBio Antibodies in human, mouse, rat for FRG2
    Customized transgenic rodents for:
     Humanization
     Biomarker expression
     Off-target effect monitoring
     Translational medicine
     Tissue-specific gene expresssion
     Time-controlled gene expresssion
           
    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 3 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

    View Random Gene

    Category
    (GIFtS: 73)
    transforming growth factor, beta 1
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      FRG2 gene at Home site.
    hostname: 356977-web1.xennexinc.com index build: 106 solr: 1.4