Aliases for FRAT2 Gene
External Ids for FRAT2 Gene
Previous GeneCards Identifiers for FRAT2 Gene
The protein encoded by this intronless gene belongs to the GSK-3-binding protein family. Studies show that this protein plays a role as a positive regulator of the WNT signaling pathway. It may be upregulated in tumor progression. [provided by RefSeq, Jul 2008]
GeneCards Summary for FRAT2 Gene
FRAT2 (Frequently Rearranged In Advanced T-Cell Lymphomas 2) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and CDK-mediated phosphorylation and removal of Cdc6. An important paralog of this gene is FRAT1.
UniProtKB/Swiss-Prot for FRAT2 Gene
Positively regulates the Wnt signaling pathway by stabilizing beta-catenin through the association with GSK-3.