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FRAT1 Gene

protein-coding GIFtS: 54

GC10P099069

frequently rearranged in advanced T-cell lymphomas
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc , and/or ⁷Ensembl, ⁸miRBase)
About This Section

Aliases
FLJ97193 ^²
Frat-1 ^³
OTTHUMP00000020201 ^²
OTTHUMP00000059391 ^²

Descriptions
GSK-3 binding protein FRAT1 ^²
frequently rearranged in advanced T-cell lymphomas ^², ³
proto-oncogene FRAT1 ^²

External Ids
HGNC: 3944¹
Entrez Gene: 10023²
UniProtKB: Q92837³
Ensembl: ENSG00000165879⁷

Search outside databases for aliases for FRAT1 gene

Previous GC identifers: GC10P097972 GC10P098312 GC10P099210 GC10P098743

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

EntrezGene summary for FRAT1:

The protein encoded by this gene belongs to the GSK-3-binding protein family. The protein inhibits

GSK-3-mediated phosphorylation of beta-catenin and positively regulates the Wnt signaling pathway.

It may function in tumor progression and in lymphomagenesis. [provided by RefSeq]

UniProtKB/Swiss-Prot: FRAT1_HUMAN, Q92837

Function: Positively regulates the Wnt signaling pathway by stabilizing beta-catenin through the

association with GSK-3. May play a role in tumor progression and collaborate with PIM1 and MYC in

lymphomagenesis

Gene Wiki entry for FRAT1

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
About This Section

Genomic View:

UCSC Golden Path with GeneCards custom track

Transcription factor binding sites upstream to the FRAT1 gene

Entrez Gene cytogenetic band: 10q24.1 Ensembl cytogenetic band: 10q24.1 HGNC chromosome: 10

FRAT1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 10 GeneLoc Exon Structure

GeneLoc location for GC10P099069: (about GC identifiers)

Start:	99,069,012 bp from pter
End:	99,071,662 bp from pter
Size:	2,651 bases
Orientation:	plus strand

RefSeq DNA sequence:

NC_000010.9 NT_030059.12

(According to ¹UniProtKB, and/or Ensembl, Phosphorylation sites according to ²Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
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UniProtKB/Swiss-Prot: FRAT1_HUMAN, Q92837 (See protein sequence)

Recommended Name: Proto-oncogene FRAT1

Size: 279 amino acids; 29093 Da

Subunit: Binds DVL1. Binds GSK-3 and prevent GSK-3-dependent phosphorylation

Subcellular location: Cytoplasm

PDB structures from and Proteopedia :

1GNG (3D)

Secondary accessions: Q5JTI1 Q8NE74 Q8TDW9

Post-translational modifications:

Phosphorylated (By similarity)¹

View phosphorylation sites using PhosphoSite²

REFSEQ proteins: NP_005470.2

ENSEMBL proteins:

ENSP00000360060

Human Recombinant Proteins

	Browse Drug Discovery Central at Invitrogen for human recombinant proteins
	Browse Purified and Recombinant Proteins at Millipore
	Browse Human Recombinant Proteins at Sigma-Aldrich
	Browse R&D Systems for human recombinant proteins
	Browse recombinant and purified proteins available from Enzo Life Sciences
	Recombinant Proteins from Abcam (FRAT1)
	Browse Abnova for Human Recombinant Proteins

Browse Origene for full length recombinant human proteins expressed in human HEK293 cells

1 Gene Ontology (GO) cellular component term (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005737	cytoplasm	IEA	--

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Antibodies for FRAT1:

	Browse Antibodies Central at Invitrogen
	Browse Millipore's Extensive Line of Mono- and Polyclonal Antibodies
	Sigma-Aldrich Antibodies for FRAT1
	Browse R&D Systems for Antibodies
	Antibodies from Abcam (FRAT1), each with their Abpromise^SM
	Monoclonal and Polyclonal Antibodies from Abnova (FRAT1)
	Novus Biologicals Antibody for FRAT1

Assays for FRAT1:

	Browse Invitrogen for biochemical assays
	Browse Kits and Assays available from Millipore
	Browse R&D Systems for biochemical assays
	Browse biochemical assays available from Enzo Life Sciences

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

Graphical View of Domain Structure for InterPro Entry Q92837

ProtoNet protein and cluster: Q92837

1 Blocks protein family: IPB008014 Glycogen synthase kinase-3 binding protein

UniProtKB/Swiss-Prot: FRAT1_HUMAN, Q92837

Similarity: Belongs to the GSK-3-binding protein family

(According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
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Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (FRAT1)
		Browse for Gene Knock-down Tools from Millipore
		Browse Abnova for Chimera RNAi Products

OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 2): NM_005479

Applied Biosystems Silencer® siRNAs for FRAT1

Sigma-Aldrich siRNA for FRAT1

Sigma-Aldrich shRNA for FRAT1

Explore Sigma-Aldrich super-pooled esiRNAs

Clones:		Browse Clone Ranger at Invitrogen for clones
		Browse Clones for the Expression of Recombinant Proteins Available from Millipore

OriGene GFP tagged cDNA clone in CMV expression vector: NM_005479
Myc/DDK tagged cDNA clone in CMV expression vector: NM_005479
untagged cDNA clone in CMV expression vector: NM_005479

Primers:

Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers

OriGene genome-wide validated SYBR primer pairs: NM_005479

UniProtKB/Swiss-Prot: FRAT1_HUMAN, Q92837

Function: Positively regulates the Wnt signaling pathway by stabilizing beta-catenin through the

association with GSK-3. May play a role in tumor progression and collaborate with PIM1 and MYC in

lymphomagenesis

1 MGI mutant phenotype (inferred from 1 allele) (MGI details for Frat1):

normal

(Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to ¹UniProtKB, ²MINT, and/or ³STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
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1 Sigma-Aldrich "Your Favorite Gene" Pathway for FRAT1 (Your Favorite Gene powered by Ingenuity)

Wnt/&beta

GeneDecks FRAT1 for the pathways selected above

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Gene Network Central^TM Interacting Genes and Proteins Network for FRAT1

5/19 Interacting proteins for FRAT1 (ENSP00000360060³) via UniProtKB, MINT, and/or STRING (see all 19 )

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
GSK3B	ENSP00000324806³	STRING (score=.999)
GSK3A	ENSP00000222330³	STRING (score=.996)
DVL1L1	ENSP00000368166³	STRING (score=.994)
CTNNB1	ENSP00000344456³	STRING (score=.986)
APC	ENSP00000257430³	STRING (score=.899)

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2 Gene Ontology (GO) biological process terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0000578	embryonic axis specification	IEA	--
GO:0016055	Wnt receptor signaling pathway	IEA	--

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(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
About This Section

Browse drugs & compounds from Enzo Life Sciences

Browse Small Molecules at Sigma-Aldrich

Browse Tocris compounds for FRAT1
1 Novoseek chemical compound relationship for FRAT1 gene

Compound	Score	Articles	PubMed IDs for Articles with Shared Sentences (# sentences)
glycogen	59.31	4	11696357 (2), 16982607 (2)

About this table

(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Invitrogen, Millipore, and/or Abnova,
siRNAs from Applied Biosystems, Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene,
Tagged/untagged cDNA clones from OriGene,
Expression Assays from Applied Biosystems)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (FRAT1)
		Browse for Gene Knock-down Tools from Millipore
		Browse Abnova for Chimera RNAi Products

OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 2): NM_005479

Sigma-Aldrich siRNA for FRAT1

Sigma-Aldrich shRNA for FRAT1

Explore Sigma-Aldrich super-pooled esiRNAs

Applied Biosystems Silencer® siRNAs:

NM_005479

REFSEQ mRNAs for FRAT1 gene:

NM_005479.3

Applied Biosystems TaqMan ® Gene Expression Assays:

NM_005479

              OriGene GFP tagged cDNA clone in CMV expression vector: NM_005479
                                 Myc/DDK tagged cDNA clone in CMV expression vector: NM_005479
                                 untagged cDNA clone in CMV expression vector: NM_005479

Additional cDNA sequence:

AB074890.1 AK307245.1 BC034476.1 U58975.2

2 DOTS entries:

DT.402798 DT.75131198

24/44 AceView cDNA sequences (see all 44 ):

AW044654 CB995777 BF590725 CA430832 AW516905 BQ016991 AA505867 BF057528

BF435283 AI457511 BC034476 AI761616 AB074890 BQ015843 AI470157 AI762217

BM995907 AA906070 BM046320 NM_005479 CD105547 NM_181355 AI685156 BF055357

highest scoring ESTs for FRAT1:

AI457511 AA454723 AA454773 AA505867 AA789305 AA888915 AA906070 AB074890 AI470157 AI652791

Unigene Clusters for FRAT1:

Frequently rearranged in advanced T-cell lymphomas

Hs.126057 [show with all ESTs], Hs.715785 [show with all ESTs]

Unigene Representative Sequences: NM_005479, U58975

GeneLoc Exon Structure

1 Ensembl transcript including schematic representation:

ENST00000371021

(Experimental results according to ¹GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to ²GeneAnnot , ³GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Expression Assays from Applied Biosystems )
About This Section

FRAT1 expression in normal and diseased human tissues

Applied Biosystems TaqMan ® Gene Expression Assays for FRAT1

¹ / ² / ³

3 probe-sets matching FRAT1 gene

Affymetrix probe-set	Array	# genes	Sensitivity	Specificity	Correlation	Length	Gb_Accession	Consensus	Uniqueness	Score	Rank
Affymetrix probe-set	Array	GeneAnnot data			GeneNote data		GeneTide data
81909_at²^{, 3}	U95-E	1	1.00	1.00	1.00	1.00	AI457511	1.00	1.00	1.00	1
219889_at²^{, 3}	U133-A	1	1.00	1.00	--	--	NM_005479	0.60	1.00	0.82	1
219889_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--

GeneDecks FRAT1 for binary patterns associated with the probe-sets selected above

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Data from

(Publications) and GNF BioGPS
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About these images

CGAP SAGE TAG: GTGAAGTGCT

SOURCE GeneReport for Unigene clusters: Hs.126057 Hs.715785

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD and/or ⁵MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
About This Section

Orthologs for FRAT1 gene from 3 species

Organism	Gene	Locus	Description	Human Similarity	NCBI accessions
chimpanzee (Pan troglodytes)	FRAT1¹	--	frequently rearranged in advanced T-cell lymphomas	99.64(n) 98.92(a)	466169 XM_521571.2 XP_521571.1
cow (Bos taurus)	FRAT1¹	--	frequently rearranged in advanced T-cell lymphomas	86.01(n) 83.94(a)	505664 XM_581986.3 XP_581986.3
mouse (Mus musculus)	Frat1^{1, 5}	19 (37.50 cM)⁵	frequently rearranged in advanced T-cell lymphomas^{1, 5}	82.11(n)¹ 78.68(a)¹	14296¹ NM_008043.2¹ NP_032069.2¹ AA591714⁵ AK015680⁵ (see all 9)

About this table Species with no ortholog for FRAT1

ENSEMBL Gene Tree for FRAT1

(Paralogs according to ¹HomoloGene
and ²Ensembl, Pseudogenes according to ³Pseudogene.org)
About This Section

Paralogs for FRAT1 gene

FRAT2²

(According to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
About This Section

3 NCBI SNPs in FRAT1 are shown
(Click for Applied Biosystems TaqMan ® Genotyping Assay) (only AB snps)

AB	SNP ID	Valid	Chr 10 pos	Sequence	Recs	AA Chg	Type	More	Recs	Allele freq	Pop	Total sample	More
AB	Genomic Data				Transcription Data				Allele Frequencies
				--	--	--		--	--				--
	rs1932002^1,2	A,C,F,H	99067669(+)	`AACAGC/GTATTT`	1	--	ng5¹		4		EU EA WA	420
--	rs3758583^1,2	--	99067330(+)	`AGGCTA/GGGCGC`	1	--	ng5¹		0	--	--	--	--
--	rs11189126^1,2	--	99067570(+)	`tccagC/Tctggg`	1	--	ng5¹		0	--	--	--	--

About this table
The following additional 22 SNP(s) have been found in Applied Biosystems data source:

(Click for Applied Biosystems TaqMan ® Genotyping Assay)

rs12240590	rs34288920	rs3781373	rs4919090	rs11189131	rs11189132	rs35717991
rs3740514	rs61746141	rs4919088	rs11593801	rs3824786	rs4919087	rs10882898
rs1334891	rs3740513	rs10786330	rs4919093	rs10786327	rs1334892	rs4919089
rs10748696

HapMap Linkage Disequilibrium images for FRAT1 (up to first 250kb)

(in which this Gene is Involved, According to OMIM, UniProtKB, Novoseek, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
About This Section

OMIM: 602503

3 Novoseek disease relationships for FRAT1 gene

Disease	Score	Articles	PubMed IDs for Articles with Shared Sentences (# sentences)
lymphoma t-cell	60.58	3	11696357 (1), 15073180 (1), 9034327 (1)
leukemia	18.84	1	15073180 (1)
tumors	0.00	14	9034327 (4), 15073180 (1)

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(Possibly Related Articles in Doctor's Guide)
About This Section

(in PubMed. Associations of this gene to articles via ¹Novoseek, ²HGNC, ³Entrez Gene, ⁴UniProtKB/Swiss-Prot, ⁵UniProtKB/TrEMBL, ⁶GAD, and/or ⁷PharmGKB)
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10/18 PubMed articles for FRAT1 gene (see all 18 ):

Activation of a novel proto-oncogene, Frat1, contributes to progression of mouse T-cell lymphomas. (PubMed id 9034327)^{1, 2, 3, 4} Jonkers J.... Berns A. (1997)
Molecular cloning and expression of proto-oncogene FRAT1 in human cancer. (PubMed id 11894125)^{1, 3, 4} Saitoh T.... Katoh M. (2002)
Casein kinase I epsilon enhances the binding of Dvl-1 to Frat-1 and is essential for Wnt-3a-induced accumulation of beta-catenin. (PubMed id 12556519)^{1, 3, 4} Hino S.... Kikuchi A. (2003)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{3, 4} Gerhard D.S....Malek J. (2004)
The DNA sequence and comparative analysis of human chromosome 10. (PubMed id 15164054)^{3, 4} Deloukas P.... Rogers J. (2004)
The structure of phosphorylated GSK-3beta complexed with a peptide, FRATtide, that inhibits beta-catenin phosphorylation. (PubMed id 11738041)^{3, 4} Bax B....Reith A.D. (2001)
FRAT1, a substrate-specific regulator of glycogen synthase kinase-3 activity, is a cellular substrate of protein kinase A. (PubMed id 16982607)^{1, 3} Hagen T....Reith A.D. (2006)
Tissue microarray analysis of human FRAT1 expression and its correlation with the subcellular localisation of beta-catenin in ovarian tumours. (PubMed id 16479254)^{1, 3} Wang Y....Xu N. (2006)
Axin and Frat1 interact with dvl and GSK, bridging Dvl to GSK in Wnt-mediated regulation of LEF-1. (PubMed id 10428961)^{1, 3} Li L....Wu D. (1999)
FRAT1 overexpression leads to aberrant activation of beta-catenin/TCF pathway in esophageal squamous cell carcinoma. (PubMed id 18498136)³ Wang Y....Xu N. (2008)

(in PubMed, OMIM, and NCBI Bookshelf)
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		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
About This Section

Entrez Gene: 10023	HGNC: 3944	AceView: FRAT1	Ensembl:ENSG00000165879	euGenes: HUgn10023
ECgene: FRAT1	H-InvDB: FRAT1

(According to HUGE)
About This Section

(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
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Name	Description
ATLAS Chromosomes in Cancer entry for FRAT1	Genetics and Cytogenetics in Oncology and Haematology

Licensable Technologies for FRAT1
(Available from WIS Yeda, Salk, Tufts)

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(Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
Enzo Life Sciences, and/or Tocris Bioscience)
About This Section

Products for FRAT1:

TaqMan ® Gene Expression Assays

TaqMan ® Genotyping Assays

Free SNP selection tool

Invitrogen iPath Pathways	Invitrogen BLOCK-iT™ RNAi
Invitrogen Antibodies	Invitrogen Assays
Invitrogen Clones	Invitrogen Q-PCR Products
Invitrogen Human Recombinant Kinases	Invitrogen Custom Antibody and Peptide Service
Invitrogen Proteins / Assays / Screening Services	Search Invitrogen catalog for FRAT1-related products

	Millipore Custom Antibody & Bulk Services
	Millipore Preclinical / Clinical Development Services
	Millipore Immunoassay Services
	Millipore Target Screening & Profiling Services

	Predesigned and custom siRNAs for FRAT1		Antibodies for FRAT1
	Explore super-pooled esiRNAs		Browse proteins at Sigma-Aldrich
	Lentivirus-delivered shRNAs for FRAT1		Browse small molecules at Sigma-Aldrich
	"Your Favorite Gene" Pathways		feedback

	Antibodies		Primer Pairs
	Cell Culture Products		ELISAs
	Flow Cytometry Kits		Protease Activity Assays & Reagents
	Cell Selection/Detection Kits & Reagents		ELISA/Assay Development Kits & Reagents
	Multiplex/Array Assay Kits & Reagents		ELISpot Kits & Development Modules
	Recombinant & Natural Proteins

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Search Tocris compounds for FRAT1

Search www.enzolifesicences.com for proteins, assays, substrates, inhibitors & antibodies

Antibodies for FRAT1

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FRAT1 Gene

protein-coding GIFtS: 54

Aliases &
Descriptions
for FRAT1

Summaries
for FRAT1

Genomic Location
for FRAT1

Proteins
for FRAT1

Protein Domains/
Families
for FRAT1

Gene Function
for FRAT1

Pathways & Interactions
for FRAT1

Drugs & Compounds
for FRAT1

Transcripts
for FRAT1

Expression
for FRAT1

Orthologs
for FRAT1

Paralogs
for FRAT1

SNPs/Variants
for FRAT1

Disorders & Mutations
for FRAT1

Medical News
for FRAT1

Publications
for FRAT1

Search for FRAT1

Genome Databases showing FRAT1

Other Databases showing FRAT1

Specialized Databases showing FRAT1

Licensable Technologies
for FRAT1

Services
for FRAT1

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

FRAT1 Gene

protein-coding GIFtS: 54

Aliases & Descriptionsfor FRAT1

Summariesfor FRAT1

Genomic Locationfor FRAT1

Proteinsfor FRAT1

Protein Domains/Familiesfor FRAT1

Gene Functionfor FRAT1

Pathways & Interactionsfor FRAT1

Drugs & Compoundsfor FRAT1

Transcriptsfor FRAT1

Expression for FRAT1

Orthologsfor FRAT1

Paralogsfor FRAT1

SNPs/Variantsfor FRAT1

Disorders & Mutationsfor FRAT1

Medical Newsfor FRAT1

Publicationsfor FRAT1

Search for FRAT1

Genome Databases showing FRAT1

Other Databases showing FRAT1

Specialized Databases showing FRAT1

Licensable Technologiesfor FRAT1

Servicesfor FRAT1

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Aliases &
Descriptions
for FRAT1

Summaries
for FRAT1

Genomic Location
for FRAT1

Proteins
for FRAT1

Protein Domains/
Families
for FRAT1

Gene Function
for FRAT1

Pathways & Interactions
for FRAT1

Drugs & Compounds
for FRAT1

Transcripts
for FRAT1

Expression
for FRAT1

Orthologs
for FRAT1

Paralogs
for FRAT1

SNPs/Variants
for FRAT1

Disorders & Mutations
for FRAT1

Medical News
for FRAT1

Publications
for FRAT1

Licensable Technologies
for FRAT1

Services
for FRAT1