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Aliases for FPGT-TNNI3K Gene

Aliases for FPGT-TNNI3K Gene

  • FPGT-TNNI3K Readthrough 2 3

External Ids for FPGT-TNNI3K Gene

Summaries for FPGT-TNNI3K Gene

Entrez Gene Summary for FPGT-TNNI3K Gene

  • This locus represents naturally occurring read-through transcription from the neighboring fucose-1-phosphate guanylyltransferase (FPGT) and TNNI3 interacting kinase (TNNI3K) genes. Alternative splicing results in multiple transcript variants that are composed of in-frame exons from each individual gene. [provided by RefSeq, Dec 2010]

GeneCards Summary for FPGT-TNNI3K Gene

FPGT-TNNI3K (FPGT-TNNI3K Readthrough) is a Protein Coding gene. An important paralog of this gene is MAP3K9.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FPGT-TNNI3K Gene

Genomics for FPGT-TNNI3K Gene

Genomic Location for FPGT-TNNI3K Gene

Start:
74,198,212 bp from pter
End:
74,544,432 bp from pter
Size:
346,221 bases
Orientation:
Plus strand

Genomic View for FPGT-TNNI3K Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for FPGT-TNNI3K Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for FPGT-TNNI3K Gene

No data available for Regulatory Elements for FPGT-TNNI3K Gene

Proteins for FPGT-TNNI3K Gene

  • Protein details for FPGT-TNNI3K Gene (UniProtKB/TrEMBL)

    Protein Symbol:
    A6NHC7-A6NHC7
    Recommended name:
    Protein FPGT-TNNI3K
    Protein Accession:
    A6NHC7
    Secondary Accessions:

    Protein attributes for FPGT-TNNI3K Gene

    Size:
    151 amino acids
    Molecular mass:
    17293 Da
    Quaternary structure:
    No Data Available
  • Protein details for FPGT-TNNI3K Gene (UniProtKB/TrEMBL)

    Protein Symbol:
    E9PKE1-E9PKE1
    Recommended name:
    Protein FPGT-TNNI3K
    Protein Accession:
    E9PKE1
    Secondary Accessions:

    Protein attributes for FPGT-TNNI3K Gene

    Size:
    162 amino acids
    Molecular mass:
    18040 Da
    Quaternary structure:
    No Data Available
  • Protein details for FPGT-TNNI3K Gene (UniProtKB/TrEMBL)

    Protein Symbol:
    V9GXZ4-V9GXZ4
    Recommended name:
    Protein FPGT-TNNI3K
    Protein Accession:
    V9GXZ4
    Secondary Accessions:

    Protein attributes for FPGT-TNNI3K Gene

    Size:
    949 amino acids
    Molecular mass:
    105589 Da
    Quaternary structure:
    No Data Available

neXtProt entry for FPGT-TNNI3K Gene

Proteomics data for FPGT-TNNI3K Gene at MOPED

Post-translational modifications for FPGT-TNNI3K Gene

No Post-translational modifications

Other Protein References for FPGT-TNNI3K Gene

No data available for DME Specific Peptides for FPGT-TNNI3K Gene

Domains for FPGT-TNNI3K Gene

genes like me logo Genes that share domains with FPGT-TNNI3K: view

No data available for Gene Families and UniProtKB/Swiss-Prot for FPGT-TNNI3K Gene

Function for FPGT-TNNI3K Gene

Gene Ontology (GO) - Molecular Function for FPGT-TNNI3K Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004672 protein kinase activity --
GO:0004713 protein tyrosine kinase activity --
GO:0005515 protein binding --
GO:0005524 ATP binding --
GO:0016772 transferase activity, transferring phosphorus-containing groups --
genes like me logo Genes that share ontologies with FPGT-TNNI3K: view

Phenotypes for FPGT-TNNI3K Gene

genes like me logo Genes that share phenotypes with FPGT-TNNI3K: view

miRNA for FPGT-TNNI3K Gene

miRTarBase miRNAs that target FPGT-TNNI3K

No data available for Molecular function , Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targeting and HOMER Transcription for FPGT-TNNI3K Gene

Localization for FPGT-TNNI3K Gene

No data available for Gene Ontology (GO) - Cellular Components for FPGT-TNNI3K Gene

Pathways for FPGT-TNNI3K Gene

SuperPathways for FPGT-TNNI3K Gene

No Data Available

Interacting Proteins for FPGT-TNNI3K Gene

Gene Ontology (GO) - Biological Process for FPGT-TNNI3K Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006468 protein phosphorylation --
genes like me logo Genes that share ontologies with FPGT-TNNI3K: view

No data available for Pathways by source for FPGT-TNNI3K Gene

Transcripts for FPGT-TNNI3K Gene

mRNA/cDNA for FPGT-TNNI3K Gene

(2) REFSEQ mRNAs :
(6) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for FPGT-TNNI3K Gene

No ASD Table

Relevant External Links for FPGT-TNNI3K Gene

GeneLoc Exon Structure for
FPGT-TNNI3K
ECgene alternative splicing isoforms for
FPGT-TNNI3K

Expression for FPGT-TNNI3K Gene

mRNA expression in normal human tissues for FPGT-TNNI3K Gene

mRNA differential expression in normal tissues according to GTEx for FPGT-TNNI3K Gene

This gene is overexpressed in Heart - Left Ventricle (7.7), Brain - Cerebellar Hemisphere (6.0), and Brain - Cerebellum (5.6).
genes like me logo Genes that share expressions with FPGT-TNNI3K: view

Orthologs for FPGT-TNNI3K Gene

This gene was present in the common ancestor of animals.

Orthologs for FPGT-TNNI3K Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia TNNI3K 37
  • 98 (a)
OneToMany
cow
(Bos Taurus)
Mammalia TNNI3K 37
  • 95 (a)
OneToMany
dog
(Canis familiaris)
Mammalia TNNI3K 37
  • 93 (a)
OneToMany
mouse
(Mus musculus)
Mammalia Tnni3k 37
  • 90 (a)
OneToMany
oppossum
(Monodelphis domestica)
Mammalia TNNI3K 37
  • 88 (a)
OneToMany
platypus
(Ornithorhynchus anatinus)
Mammalia -- 37
  • 93 (a)
ManyToMany
-- 37
  • 14 (a)
ManyToMany
-- 37
  • 86 (a)
ManyToMany
chicken
(Gallus gallus)
Aves TNNI3K 37
  • 90 (a)
OneToMany
lizard
(Anolis carolinensis)
Reptilia -- 37
  • 91 (a)
OneToMany
zebrafish
(Danio rerio)
Actinopterygii tnni3k 37
  • 84 (a)
OneToMany
worm
(Caenorhabditis elegans)
Secernentea C24A1.3 37
  • 42 (a)
OneToMany
Species with no ortholog for FPGT-TNNI3K:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)

Evolution for FPGT-TNNI3K Gene

ENSEMBL:
Gene Tree for FPGT-TNNI3K (if available)
TreeFam:
Gene Tree for FPGT-TNNI3K (if available)

Paralogs for FPGT-TNNI3K Gene

genes like me logo Genes that share paralogs with FPGT-TNNI3K: view

Variants for FPGT-TNNI3K Gene

Sequence variations from dbSNP and Humsavar for FPGT-TNNI3K Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type MAF
rs471496 -- 74,218,222(+) TTTAT(A/G)TTCTC intron-variant
rs477134 -- 74,213,230(+) GGAAG(G/T)TGCTG intron-variant
rs485929 -- 74,212,601(+) AAGGA(A/G)AGATT intron-variant
rs488813 -- 74,212,920(+) GTTGA(A/G)CCTCT intron-variant
rs489026 -- 74,223,931(+) ggacc(C/T)ggaga intron-variant

Structural Variations from Database of Genomic Variants (DGV) for FPGT-TNNI3K Gene

Variant ID Type Subtype PubMed ID
nsv522147 CNV Loss 19592680
dgv245n71 CNV Gain 21882294
dgv246n71 CNV Gain 21882294
dgv247n71 CNV Loss 21882294
nsv870852 CNV Loss 21882294
nsv523474 CNV Loss 19592680
nsv870653 CNV Loss 21882294
nsv871150 CNV Loss 21882294
nsv871467 CNV Gain+Loss 21882294
dgv248n71 CNV Loss 21882294
dgv249n71 CNV Loss 21882294
esv6294 CNV Gain 19470904
esv2749941 CNV Deletion 23290073
esv2350476 CNV Deletion 18987734
esv4202 CNV Deletion 18987735
esv1000471 CNV Deletion 20482838
esv1327381 CNV Deletion 17803354
esv2749952 CNV Deletion 23290073
nsv870654 CNV Loss 21882294
nsv461984 CNV Loss 19166990
esv2660597 CNV Deletion 23128226
nsv820047 CNV Loss 19587683
esv274525 CNV Insertion 20981092
nsv830248 CNV Loss 17160897
nsv525557 CNV Loss 19592680
nsv871900 CNV Loss 21882294
esv2549117 CNV Deletion 19546169
esv1932816 CNV Deletion 18987734
esv2749963 CNV Deletion 23290073

Relevant External Links for FPGT-TNNI3K Gene

HapMap Linkage Disequilibrium report
FPGT-TNNI3K

Disorders for FPGT-TNNI3K Gene

No disorders were found for FPGT-TNNI3K Gene.

No data available for UniProtKB/Swiss-Prot for FPGT-TNNI3K Gene

Publications for FPGT-TNNI3K Gene

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3
  2. Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index. (PMID: 20935630) Speliotes E.K. … Loos R.J. (Nat. Genet. 2010) 3
  3. Expression of conjoined genes: another mechanism for gene regulation in eukaryotes. (PMID: 20967262) Prakash T. … Taylor T.D. (PLoS ONE 2010) 3
  4. Genome-wide association and longitudinal analyses reveal genetic loci linking pubertal height growth, pubertal timing and childhood adiposity. (PMID: 23449627) Cousminer D.L. … WidAcn E. (Hum. Mol. Genet. 2013) 3
  5. Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture. (PMID: 23563607) Berndt S.I. … Ingelsson E. (Nat. Genet. 2013) 3

Products for FPGT-TNNI3K Gene

Sources for FPGT-TNNI3K Gene

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