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FOXS1 Gene

protein-coding   GIFtS: 47
GCID: GC20M030432

Forkhead Box S1

(Previous names: forkhead (Drosophila)-like 18, forkhead-like 18 (Drosophila))
(Previous symbol: FKHL18)
  See related disease
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Forkhead Box S11 2     Forkhead (Drosophila)-Like 181
FKHL181 2 3 5     Forkhead-Like 18 (Drosophila)1
FREAC102 3 5     Forkhead Box Protein S12
Forkhead-Like 18 Protein2 3     Forkhead-Related Activator 102
Forkhead-Related Transcription Factor 102 3     Forkhead-Related Transcription Factor FREAC-102
FREAC-102 3     

External Ids:    HGNC: 37351   Entrez Gene: 23072   Ensembl: ENSG000001797727   OMIM: 6029395   UniProtKB: O436383   

Export aliases for FOXS1 gene to outside databases

Previous GC identifers: GC20M029896 GC20M027221


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for FOXS1 Gene:
The forkhead family of transcription factors belongs to the winged helix class of DNA-binding proteins. The
protein encoded by this intronless gene contains a forkhead domain and is found predominantly in aorta and
kidney. The function of the encoded protein is unknown. (provided by RefSeq, Jul 2008)

GeneCards Summary for FOXS1 Gene:
FOXS1 (forkhead box S1) is a protein-coding gene. Diseases associated with FOXS1 include endotheliitis. GO annotations related to this gene include transcription factor binding and sequence-specific DNA binding transcription factor activity. An important paralog of this gene is FOXA2.

UniProtKB/Swiss-Prot: FOXS1_HUMAN, O43638
Function: Transcriptional repressor that suppresses transcription from the FASLG, FOXO3 and FOXO4 promoters. May
have a role in the organization of the testicular vasculature (By similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000020.11  NC_018931.2  NT_011362.11  
Regulatory elements:
   Regulatory transcription factor binding sites in the FOXS1 gene promoter:
         SRF   AhR   AML1a   GCNF   SRF (504 AA)   Nkx2-5   NF-kappaB   GATA-2   GCNF-1   GCNF-2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidFOXS1 promoter sequence
   Search Chromatin IP Primers for FOXS1

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat FOXS1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 20q11.21   Ensembl cytogenetic band:  20q11.21   HGNC cytogenetic band: 20q11.1-q11.2

FOXS1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
FOXS1 gene location

GeneLoc information about chromosome 20         GeneLoc Exon Structure

GeneLoc location for GC20M030432:  view genomic region     (about GC identifiers)

Start:
30,432,103 bp from pter      End:
30,433,420 bp from pter
Size:
1,318 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: FOXS1_HUMAN, O43638 (See protein sequence)
Recommended Name: Forkhead box protein S1  
Size: 330 amino acids; 35434 Da
Secondary accessions: Q96D28

Explore the universe of human proteins at neXtProt for FOXS1: NX_O43638

Explore proteomics data for FOXS1 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See FOXS1 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_004109.1  
    ENSEMBL proteins: 
     ENSP00000365145  

    FOXS1 Human Recombinant Protein Products:

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    Novus Biologicals FOXS1 Lysates
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    Browse Sino Biological Cell Lysates
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    Cloud-Clone Corp. Proteins for FOXS1

    FOXS1 Antibody Products:

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    Abcam antibodies for FOXS1
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    FOXS1 Assay Products:

    Browse Kits and Assays available from EMD Millipore
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    GenScript Custom Assay Services for FOXS1
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for FOXS1
    Cloud-Clone Corp. CLIAs for FOXS1


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    FOX: Forkhead boxes

    3 InterPro protein domains:
     IPR011991 WHTH_DNA-bd_dom
     IPR018122 TF_fork_head_CS
     IPR001766 TF_fork_head

    Graphical View of Domain Structure for InterPro Entry O43638

    ProtoNet protein and cluster: O43638

    UniProtKB/Swiss-Prot: FOXS1_HUMAN, O43638
    Similarity: Contains 1 fork-head DNA-binding domain


    FOXS1 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: FOXS1_HUMAN, O43638
    Function: Transcriptional repressor that suppresses transcription from the FASLG, FOXO3 and FOXO4 promoters. May
    have a role in the organization of the testicular vasculature (By similarity)

         Gene Ontology (GO): Selected molecular function terms (see all 8):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003677DNA binding ISS--
    GO:0003690double-stranded DNA binding IBA--
    GO:0003700sequence-specific DNA binding transcription factor activity TAS9325056
    GO:0003705RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity IBA--
    GO:0008134transcription factor binding IBA--
         
    FOXS1 for ontologies           About GeneDecksing


    Phenotypes:
         2 GenomeRNAi human phenotypes for FOXS1:
     Elongated cells  Increased HPV18 LCR reporter a 

         6 MGI mutant phenotypes (inferred from 3 alleles(MGI details for Foxs1):
     behavior/neurological  cardiovascular system  growth/size/body  homeostasis/metabolism  no phenotypic analysis 
     reproductive system 

    FOXS1 for phenotypes           About GeneDecksing

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for FOXS1
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for FOXS1

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for FOXS1
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for FOXS1

    miRNA
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    Block miRNA regulation of human, mouse, rat FOXS1 using miScript Target Protectors
    5 qRT-PCR Assays for microRNAs that regulate FOXS1:
    hsa-miR-328 hsa-miR-125a-5p hsa-miR-125b hsa-miR-1291 hsa-miR-4319
    SwitchGear 3'UTR luciferase reporter plasmidFOXS1 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for FOXS1
    Predesigned siRNA for gene silencing in human, mouse, rat FOXS1

    Gene Editing
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    Clone
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    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: FOXS1 (NM_004118)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for FOXS1
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FOXS1

    Cell Line
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    ESI BIO PureStem Progenitor for FOXS1: 
    PureStem ES-210, Ecto-ntu Progenitor
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FOXS1


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    FOXS1_HUMAN, O43638: Nucleus (By similarity)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus3
    cytosol1

    Gene Ontology (GO): 2 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus ISS--
    GO:0005667transcription factor complex IBA--

    FOXS1 for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for FOXS1
    Interactions:

        Search GeneGlobe Interaction Network for FOXS1

    STRING Interaction Network Preview (showing 5 interactants - click image to see more details)

    5 Interacting proteins for FOXS1 (O436382, 3 ENSP000003651454) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    RBPMSQ930622, 3, ENSP000003401764MINT-66155 I2D: score=5 STRING: ENSP00000340176
    BMI1P352263, ENSP000003658514I2D: score=1 STRING: ENSP00000365851
    CDC5LENSP000003605324STRING: ENSP00000360532
    DDX46ENSP000003462364STRING: ENSP00000346236
    ZFC3H1ENSP000003680174STRING: ENSP00000368017
    About this table

    Gene Ontology (GO): Selected biological process terms (see all 31):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000122negative regulation of transcription from RNA polymerase II promoter IBA--
    GO:0001503ossification IBA--
    GO:0001568blood vessel development ISS--
    GO:0001569patterning of blood vessels IBA--
    GO:0001656NOT metanephros development IBA--

    FOXS1 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for FOXS1



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for FOXS1 gene: 
    NM_004118.3  

    Unigene Cluster for FOXS1:

    Forkhead box S1
    Hs.516971  [show with all ESTs]
    Unigene Representative Sequence: NM_004118
    1 Ensembl transcript including schematic representation, and UCSC links where relevant:
    ENST00000375978(uc002wwt.1)
    miRNA
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    Block miRNA regulation of human, mouse, rat FOXS1 using miScript Target Protectors
    5 qRT-PCR Assays for microRNAs that regulate FOXS1:
    hsa-miR-328 hsa-miR-125a-5p hsa-miR-125b hsa-miR-1291 hsa-miR-4319
    SwitchGear 3'UTR luciferase reporter plasmidFOXS1 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat FOXS1
    Clone
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    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: FOXS1 (NM_004118)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for FOXS1
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FOXS1
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for FOXS1
    OriGene qSTAR qPCR primer pairs in human, mouse for FOXS1
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat FOXS1
      QuantiTect SYBR Green Assays in human, mouse, rat FOXS1
      QuantiFast Probe-based Assays in human, mouse, rat FOXS1

    Additional mRNA sequence: 

    AF042831.1 BC013408.2 BT009768.1 

    1 DOTS entry:

    DT.40127131 

    Selected AceView cDNA sequences (see all 31):

    BQ222153 NM_004118 BX118273 BC013408 AI291494 BE298313 BF203443 AW006727 
    AF042831 AI798630 BF512876 BF309576 BF307143 BF064268 AI868759 AI457594 
    AI401807 BT009768 BE298597 BF064278 BF310028 BG413453 AI370851 AI739404 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    FOXS1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TGATGATGAG
    FOXS1 Expression
    About this image


    FOXS1 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 4) fully expand
     
     Paraxial Mesoderm (Gastrulation Derivatives)
             PureStem E15, Meso-prx/latp Progenitor
     
     Heart (Cardiovascular System)
             Atrioventricular Node Cells Atrioventricular Node
     
     Umbilical Cord (Extraembryonic Tissues)
             Wharton's jelly-derived stem cells
     
     Lateral Plate Mesoderm (Gastrulation Derivatives)
             PureStem E15, Meso-prx/latp Progenitor
    FOXS1 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    FOXS1 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.516971
        Custom PCR Arrays for FOXS1
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FOXS1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for FOXS1 gene from Selected species (see all 11)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Foxs11 , 5 forkhead box S11, 5 79.53(n)1
    75.68(a)1
      2 (75.41 cM)5
    142391  NM_010226.21  NP_034356.11 
     1529318985 
    chicken
    (Gallus gallus)
    Aves FOXS11 forkhead box S1 64.25(n)
    58.99(a)
      428156  XM_425714.3  XP_425714.2 
    lizard
    (Anolis carolinensis)
    Reptilia FOXS16
    forkhead box S1
    43(a)
    1 ↔ 1
    GL344261.1(25776-26963)
    zebrafish
    (Danio rerio)
    Actinopterygii foxc1b6
    forkhead box C1b
    26(a)
    many ↔ many
    20(26731984-26733938) ENSDARG00000055398
    fruit fly
    (Drosophila melanogaster)
    Insecta croc6
    crocodile
    20(a)
    1 → many
    3L(21467233-21469579)


    ENSEMBL Gene Tree for FOXS1 (if available)
    TreeFam Gene Tree for FOXS1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for FOXS1 gene
    FOXA22  FOXD4L12  FOXC22  FOXI22  FOXB12  FOXE32  FOXC12  FOXD4L22  
    FOXD4L32  FOXA32  FOXD4L52  FOXD12  FOXD32  FOXD4L42  FOXA12  FOXE12  
    FOXL12  FOXB22  FOXI12  FOXD4L62  FOXD22  FOXL22  FOXD42  
    11 SIMAP similar genes for FOXS1 using alignment to 1 protein entry:     FOXS1_HUMAN:
    FOXC1    FOXI2    FOXD4L5    FOXD4L3    FOXA3    FOXI3
    FOXI1    FOXA2    FOXB1    FOXC2    FOXD1

    FOXS1 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for FOXS1 (see all 156)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 20 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1483376731,2
    --30431637(+) GATGTA/GGTTTT 1 -- ds50010--------
    rs1855820721,2
    --30431712(+) TAAACA/GGGGCC 1 -- ds50010--------
    rs60890941,2
    C,F,A,H--30431771(+) GATCAG/ATGTCA 1 -- ds500125Minor allele frequency- A:0.32NS EA NA WA 2464
    rs1904408061,2
    --30431821(+) AAGTCC/TCAGCA 1 -- ds50010--------
    rs1420210561,2
    --30432019(+) TGCCCC/TCGCTG 1 -- ds50010--------
    rs61212451,2
    C,F,A--30432060(+) TACAAG/ACAGGC 1 -- ds50017Minor allele frequency- A:0.40NA WA 248
    rs1825184171,2
    --30432155(+) TCCCAA/GGAGGC 1 -- ut310--------
    rs1858557241,2
    --30432274(+) CCTTCA/GAGAGT 1 -- ut310--------
    rs1433488221,2
    C,F--30432439(+) GAAGCC/TACCTG 2 S G mis11Minor allele frequency- T:0.00NA 4484
    rs22969171,2,,4
    C,H--30432472(+) AGTTGG/CCAGGG 2 /P /A mis16Minor allele frequency- C:0.01EA NS NA 1160

    HapMap Linkage Disequilibrium report for FOXS1 (30432103 - 30433420 bp)

    Structural Variations
          Database of Genomic Variants (DGV) variations for FOXS1: --
    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing FOXS1
    DNA2.0 Custom Variant and Variant Library Synthesis for FOXS1

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 602939    OMIM disorders: --

    1 disease for FOXS1:    
    About MalaCards
    endotheliitis


    FOXS1 for disorders           About GeneDecksing


    Export disorders for FOXS1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for FOXS1 gene integrated from 10 sources:
    (articles sorted by number of sources associating them with FOXS1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Chromosome localization, sequence analysis, and expression pattern identify FKHL 18 as a novel human forkhead gene. (PubMed id 9325056)1, 2, 3 Cederberg A.... Enerbaeck S. (Genomics 1997)
    2. Comparative genomics of vertebrate Fox cluster loci. (PubMed id 17062144)1, 3 Wotton K.R. and Shimeld S.M. (BMC Genomics 2006)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    4. The DNA sequence and comparative analysis of human chromosome 20. (PubMed id 11780052)1, 2 Deloukas P....Rogers J. (Nature 2001)
    5. Interactions of pathological hallmark proteins: tubulin polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. (PubMed id 21832049)1 OlA!h J....OvA!di J. (J. Biol. Chem. 2011)
    6. An atlas of combinatorial transcriptional regulation in mouse and man. (PubMed id 20211142)1 Ravasi T....Hayashizaki Y. (Cell 2010)
    7. Towards a proteome-scale map of the human protein-protein interaction network. (PubMed id 16189514)1 Rual J.F....Vidal M. (Nature 2005)
    8. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)
    9. (PubMed id )2 

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 2307 HGNC: 3735 AceView: FKHL18 Ensembl:ENSG00000179772 euGenes: HUgn2307
    ECgene: FOXS1 H-InvDB: FOXS1

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for FOXS1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for FOXS1 gene:
    Search GeneIP for patents involving FOXS1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, and ESI BIO, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
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