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FOXRED1 Gene

protein-coding   GIFtS: 55
GCID: GC11P126139

FAD-Dependent Oxidoreductase Domain Containing 1

  See FOXRED1-related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
FAD-Dependent Oxidoreductase Domain Containing 11 2
H172
FAD-Dependent Oxidoreductase Domain-Containing Protein 12
EC 1.-.-.-3

External Ids:    HGNC: 269271   Entrez Gene: 555722   Ensembl: ENSG000001100747   OMIM: 6136225   UniProtKB: Q96CU93   

Export aliases for FOXRED1 gene to outside databases

Previous GC identifers: GC11P125645 GC11P122081


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for FOXRED1 Gene:
This gene encodes a protein that contains a FAD-dependent oxidoreductase domain. The encoded protein is localized
to the mitochondria and may function as a chaperone protein required for the function of mitochondrial complex I.
Mutations in this gene are associated with mitochondrial complex I deficiency. Alternatively spliced transcript
variants have been observed for this gene. (provided by RefSeq, Dec 2010)

GeneCards Summary for FOXRED1 Gene:
FOXRED1 (FAD-dependent oxidoreductase domain containing 1) is a protein-coding gene. Diseases associated with FOXRED1 include mitochondrial complex i deficiency, and peanut allergic reaction. GO annotations related to this gene include oxidoreductase activity.

Gene Wiki entry for FOXRED1 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000011.9  NT_033899.9  NC_018922.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the FOXRED1 gene promoter:
         HFH-3   HOXA3   Brachyury   HSF1 (long)   CUTL1   c-Ets-1   FOXI1   IRF-7A   HSF1short   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidFOXRED1 promoter sequence
   Search Chromatin IP Primers for FOXRED1

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat FOXRED1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 11q24.2   Ensembl cytogenetic band:  11q24.2   HGNC cytogenetic band: 11q24.2

FOXRED1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
FOXRED1 gene location

GeneLoc information about chromosome 11         GeneLoc Exon Structure

GeneLoc location for GC11P126139:  view genomic region     (about GC identifiers)

Start:
126,138,935 bp from pter      End:
126,148,027 bp from pter
Size:
9,093 bases      Orientation:
plus strand
ORGUL member locations:
Legend (see complete legend)

ORGUL Member Locations for FOXRED1

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: FXRD1_HUMAN, Q96CU9 (See protein sequence)
Recommended Name: FAD-dependent oxidoreductase domain-containing protein 1  
Size: 486 amino acids; 53812 Da
Cofactor: FAD (By similarity)
Secondary accessions: B3KN84 B4DHU2 Q71MG0 Q9BU39 Q9UKY9
Alternative splicing: 3 isoforms:  Q96CU9-1   Q96CU9-2   Q96CU9-3   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for FOXRED1: NX_Q96CU9

Explore proteomics data for FOXRED1 at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys33, Lys42, Lys259
  • Modification sites at PhosphoSitePlus

  • See FOXRED1 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_060017.1  
    ENSEMBL proteins: 
     ENSP00000263578   ENSP00000434739   ENSP00000436374   ENSP00000434178   ENSP00000404371  

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    1 InterPro protein domain:
     IPR006076 FAD-dep_OxRdtase

    Graphical View of Domain Structure for InterPro Entry Q96CU9

    ProtoNet protein and cluster: Q96CU9


    Find genes that share domains with FOXRED1           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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         Enzyme Number (IUBMB): EC 1.-.-.-1

         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0016491oxidoreductase activity IEA--
         
    Find genes that share ontologies with FOXRED1           About GenesLikeMe


    Phenotypes:
         1 MGI phenotypic allele for Foxred1 (no phenotypes)

    Find genes that share phenotypes with FOXRED1           About GenesLikeMe

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for FOXRED1
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       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for FOXRED1
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    miRNA
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    hsa-let-7b-5p (MIRT032389), hsa-mir-324-3p (MIRT042937)

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    1 qRT-PCR Assays for microRNA that regulate FOXRED1:
    hsa-miR-1910
    SwitchGear 3'UTR luciferase reporter plasmidFOXRED1 3' UTR sequence
    Inhib. RNA
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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    FXRD1_HUMAN, Q96CU9: Membrane; Single-pass membrane protein (Potential)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    mitochondrion4
    nucleus2
    cytosol1

    Gene Ontology (GO): 2 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005739mitochondrion IDA--
    GO:0016021integral component of membrane IEA--

    Find genes that share ontologies with FOXRED1           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for FOXRED1
    Interactions:

        Search GeneGlobe Interaction Network for FOXRED1

    STRING Interaction Network Preview (showing 4 interactants - click image to see more details)

    4 Interacting proteins for FOXRED1 (Q96CU93 ENSP000002635784) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    EXOSC10Q017803, ENSP000003661354I2D: score=2 STRING: ENSP00000366135
    RTF1ENSP000003742804STRING: ENSP00000374280
    VTI1AENSP000003767924STRING: ENSP00000376792
    UBCENSP000003448184STRING: ENSP00000344818
    About this table

    Gene Ontology (GO): 2 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0008150biological_process ND--
    GO:0055114oxidation-reduction process ----

    Find genes that share ontologies with FOXRED1           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for FOXRED1 (FXRD1)

    1 HMDB Compound for FOXRED1    About this table
    CompoundSynonyms CAS #PubMed Ids
    FAD1H-Purin-6-amine flavin dinucleotide (see all 21)146-14-5--



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for FOXRED1 gene: 
    NM_017547.3  

    Unigene Cluster for FOXRED1:

    FAD-dependent oxidoreductase domain containing 1
    Hs.317190  [show with all ESTs]
    Unigene Representative Sequence: AF447877
    Selected Ensembl transcripts including schematic representations, and UCSC links where relevant (see all 19):
    ENST00000533839 ENST00000263578(uc001qdi.3 uc010sbq.2 uc010sbr.2)
    ENST00000534011(uc010sbn.2 uc010sbo.2 uc010sbp.2) ENST00000529802
    ENST00000526525 ENST00000525083 ENST00000525770 ENST00000527004 ENST00000526366
    ENST00000524751 ENST00000532101 ENST00000532125 ENST00000534315(uc001qdk.3)
    ENST00000531257 ENST00000527875 ENST00000533395 ENST00000530642 ENST00000532590

    miRNA
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    1 qRT-PCR Assays for microRNA that regulate FOXRED1:
    hsa-miR-1910
    SwitchGear 3'UTR luciferase reporter plasmidFOXRED1 3' UTR sequence
    Inhib. RNA
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      QuantiTect SYBR Green Assays in human, mouse, rat FOXRED1
      QuantiFast Probe-based Assays in human, mouse, rat FOXRED1

    Additional mRNA sequence: 

    AF103801.1 AF447877.1 AK023987.1 AK295267.1 AK295428.1 AK298010.1 AK298807.1 AK302039.1 
    AL136923.1 BC002910.2 BC013902.2 NR_037647.1 NR_037648.1 

    24 DOTS entries:

    DT.100878456  DT.40248184  DT.114456  DT.91715276  DT.100803291  DT.120713317  DT.427672  DT.120713224 
    DT.91870957  DT.91907268  DT.120713346  DT.100753995  DT.120713249  DT.120713343  DT.91916413  DT.100736587 
    DT.100878466  DT.120713203  DT.120713269  DT.120713315  DT.120713327  DT.120713337  DT.91756469  DT.95323757 

    Selected AceView cDNA sequences (see all 269):

    BQ069535 BC002910 BF935461 BM314186 CB143503 CB114822 BM915525 CR612300 
    BQ654082 AL136923 CD366263 BU957358 CR613695 BQ447371 BI087345 AL520800 
    CR618832 BI223678 AA361155 BU633350 CR624638 BE901980 BX403832 BE275704 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for FOXRED1 (see all 20)    About this scheme

    ExUns: 1a · 1b · 1c · 1d ^ 2a · 2b · 2c ^ 3a · 3b · 3c · 3d · 3e ^ 4 ^ 5a · 5b ^ 6a · 6b ^ 7a · 7b · 7c ^ 8a · 8b · 8c ^ 9 ^ 10 ^ 11a ·
    SP1:                                      -     -     -                 -     -                 -     -     -                       -     -                     
    SP2:                                      -     -     -     -     -     -     -                 -     -     -                       -     -                     
    SP3:                                      -     -     -                 -     -                 -     -     -                 -     -     -                     
    SP4:                                      -     -     -     -     -     -     -                 -     -     -                       -     -                     
    SP5:                                                                                            -     -     -                       -     -                     

    ExUns: 11b · 11c ^ 12a · 12b · 12c · 12d ^ 13a · 13b ^ 14a · 14b
    SP1:                                      -                     
    SP2:                                                            
    SP3:                                                            
    SP4:                                                            
    SP5:                                                            


    ECgene alternative splicing isoforms for FOXRED1

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    FOXRED1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TAATTAACTC
    FOXRED1 Expression
    About this image

    FOXRED1 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    FOXRED1 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.317190
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FOXRED1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for FOXRED1 gene from Selected species (see all 14)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Foxred11 , 5 FAD-dependent oxidoreductase domain containing 11, 5 82.65(n)1
    79.42(a)1
      9 (20.08 cM)5
    2351691  NM_172291.11  NP_758495.11 
     352042065 
    chicken
    (Gallus gallus)
    Aves FOXRED11 FAD-dependent oxidoreductase domain containing 1 65.5(n)
    62(a)
      419712  XM_004947957.1  XP_004948014.1 
    lizard
    (Anolis carolinensis)
    Reptilia FOXRED16
    FAD-dependent oxidoreductase domain containing 1
    59(a)
    1 ↔ 1
    GL343322.1(1098262-1108101)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia Str.168992 Transcribed sequence with weak similarity to protein more 70.99(n)    BX736164.1 
    zebrafish
    (Danio rerio)
    Actinopterygii Dr.118042 Transcribed sequence with moderate similarity to protein more 77.78(n)    AA494859.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta l(2)37Bb1 lethal (2) 37Bb 52.21(n)
    43.63(a)
      49427  NM_080530.3  NP_536791.1 
    worm
    (Caenorhabditis elegans)
    Secernentea CELE_M04B2.41 CELE_M04B2.4 46.68(n)
    40.3(a)
      178073  NM_069770.3  NP_502171.1 


    ENSEMBL Gene Tree for FOXRED1 (if available)
    TreeFam Gene Tree for FOXRED1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for FOXRED1 (see all 353)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 11 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    VAR_0645714
    Mitochondrial complex I deficiency (MT-C1D)4--see VAR_0645712 N S mis40--------
    rs730173561,2
    C,F--126003390(+) TTATAG/CGATGG 2 -- us2k11Minor allele frequency- C:0.02NA 120
    rs1461244331,2
    --126003413(+) TGAGAA/GGCAGG 2 -- us2k10--------
    rs2009227871,2
    --126003562(+) GCTTTG/TCCCCC 3 -- us2k10--------
    rs1511908121,2
    F--126003567(+) TCCCCC/TCGTGT 3 -- us2k11Minor allele frequency- T:0.00NA 4548
    rs746227861,2
    C,F--126003678(+) AACAAA/GAAGGA 3 -- us2k12Minor allele frequency- G:0.00NA EU 1443
    rs2014343771,2
    C--126003714(+) CAGAAA/GGAAAA 3 -- us2k10--------
    rs1160901541,2
    C,F--126003836(+) AGGTCA/GTCAAA 3 -- us2k11Minor allele frequency- G:0.02WA 118
    rs3764337511,2
    C--126003892(+) GGAGCC/TGCAGG 3 -- us2k10--------
    rs1156594581,2
    C,F--126003900(+) AGGAAG/ATCATT 3 -- us2k11Minor allele frequency- A:0.02EA 210

    HapMap Linkage Disequilibrium report for FOXRED1 (126138935 - 126148027 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 2 variations for FOXRED1:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv513341CNV Insertion21212237
    nsv898440CNV Loss21882294

    Human Gene Mutation Database (HGMD): FOXRED1
    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing FOXRED1
    DNA2.0 Custom Variant and Variant Library Synthesis for FOXRED1

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 613622   
    OMIM disorders: 256000  252010  
    UniProtKB/Swiss-Prot: FXRD1_HUMAN, Q96CU9
  • Mitochondrial complex I deficiency (MT-C1D) [MIM:252010]: A disorder of the mitochondrial respiratory
    chain that causes a wide range of clinical manifestations from lethal neonatal disease to adult-onset
    neurodegenerative disorders. Phenotypes include macrocephaly with progressive leukodystrophy, non-specific
    encephalopathy, cardiomyopathy, myopathy, liver disease, Leigh syndrome, Leber hereditary optic neuropathy, and
    some forms of Parkinson disease. Note=The disease is caused by mutations affecting the gene represented in this
    entry

  • 6 diseases for FOXRED1:    
    About MalaCards
    mitochondrial complex i deficiency    peanut allergic reaction    leigh syndrome due to mitochondrial complex i deficiency    mitochondrial dna deletion syndromes
    mitochondrial dna-associated leigh syndrome and narp    mitochondrial disorders

    1 disease from the University of Copenhagen DISEASES database for FOXRED1:
    Peanut allergic reaction

    Find genes that share disorders with FOXRED1           About GenesLikeMe

    Genetic Association Database (GAD): FOXRED1
    Human Genome Epidemiology (HuGE) Navigator: FOXRED1 (4 documents)

    Export disorders for FOXRED1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for FOXRED1 gene, integrated from 10 sources (see all 24):
    (articles sorted by number of sources associating them with FOXRED1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Identification of differentially expressed genes associated with HER- 2/neu overexpression in human breast cancer cells. (PubMed id 10497265)1, 2, 3 Oh J.J.... Slamon D.J. (Nucleic Acids Res. 1999)
    2. Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression. (PubMed id 20877624)1, 4 Hendrickson S.L....O'Brien S.J. (PLoS ONE 2010)
    3. High-throughput, pooled sequencing identifies mutations in NUBPL and FOXRED1 in human complex I deficiency. (PubMed id 20818383)1, 2 Calvo S.E.... Mootha V.K. (Nat. Genet. 2010)
    4. Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. (PubMed id 20628086)1, 4 Bailey S.D....Anand S. (Diabetes Care 2010)
    5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    6. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    7. Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. (PubMed id 11230166)1, 2 Wiemann S.... Poustka A. (Genome Res. 2001)
    8. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (BMC Syst. Biol. 2011)
    9. A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (amp 2011)
    10. Mass spectrometric analysis of lysine ubiquitylation reveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (amp 2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 55572 HGNC: 26927 AceView: H17 Ensembl:ENSG00000110074 euGenes: HUgn55572
    ECgene: FOXRED1 H-InvDB: FOXRED1

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for FOXRED1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for FOXRED1 gene:
    Search GeneIP for patents involving FOXRED1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
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