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FOXQ1 Gene

protein-coding   GIFtS: 50
GCID: GC06P001312

Forkhead Box Q1

  See FOXQ1-related disease
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Forkhead Box Q11 2     HNF-3/Forkhead-Like Protein 12 3
HFH12 3 5     Forkhead Box Protein Q12
Hepatocyte Nuclear Factor 3 Forkhead Homolog 12 3     Winged Helix/Forkhead Transcription Factor2
HFH-12 3     

External Ids:    HGNC: 209511   Entrez Gene: 942342   Ensembl: ENSG000001643797   OMIM: 6127885   UniProtKB: Q9C0093   

Export aliases for FOXQ1 gene to outside databases

Previous GC identifers: GC06P001302 GC06P001257


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for FOXQ1 Gene:
FOXQ1 is a member of the FOX gene family, which is characterized by a conserved 110-amino acid DNA-binding motif
called the forkhead or winged helix domain. FOX genes are involved in embryonic development, cell cycle
regulation, tissue-specific gene expression, cell signaling, and tumorigenesis (Bieller et al., 2001 (PubMed
11747606)).(supplied by OMIM, May 2009)

GeneCards Summary for FOXQ1 Gene:
FOXQ1 (forkhead box Q1) is a protein-coding gene. Diseases associated with FOXQ1 include duane retraction syndrome. GO annotations related to this gene include double-stranded DNA binding and sequence-specific DNA binding. An important paralog of this gene is FOXF1.

UniProtKB/Swiss-Prot: FOXQ1_HUMAN, Q9C009
Function: Plays a role in hair follicle differentiation (By similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000006.11  NC_018917.2  NT_007592.16  
Regulatory elements:
   Regulatory transcription factor binding sites in the FOXQ1 gene promoter:
         RFX1   Pax-5   AML1a   LCR-F1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidFOXQ1 promoter sequence
   Search Chromatin IP Primers for FOXQ1

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat FOXQ1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 6p25   Ensembl cytogenetic band:  6p25.3   HGNC cytogenetic band: 6p25

FOXQ1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
FOXQ1 gene location

GeneLoc information about chromosome 6         GeneLoc Exon Structure

GeneLoc location for GC06P001312:  view genomic region     (about GC identifiers)

Start:
1,312,675 bp from pter      End:
1,314,993 bp from pter
Size:
2,319 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: FOXQ1_HUMAN, Q9C009 (See protein sequence)
Recommended Name: Forkhead box protein Q1  
Size: 403 amino acids; 41526 Da
Secondary accessions: Q9NS06

Explore the universe of human proteins at neXtProt for FOXQ1: NX_Q9C009

Explore proteomics data for FOXQ1 at MOPED


See FOXQ1 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

REFSEQ proteins: NP_150285.3  
ENSEMBL proteins: 
 ENSP00000296839  

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Cloud-Clone Corp. CLIAs for FOXQ1
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(According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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HGNC Gene Families:
FOX: Forkhead boxes

3 InterPro protein domains:
 IPR011991 WHTH_DNA-bd_dom
 IPR018122 TF_fork_head_CS
 IPR001766 TF_fork_head

Graphical View of Domain Structure for InterPro Entry Q9C009

ProtoNet protein and cluster: Q9C009

UniProtKB/Swiss-Prot: FOXQ1_HUMAN, Q9C009
Similarity: Contains 1 fork-head DNA-binding domain


Find genes that share domains with FOXQ1           About GenesLikeMe


(According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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Molecular Function:

     UniProtKB/Swiss-Prot Summary: FOXQ1_HUMAN, Q9C009
Function: Plays a role in hair follicle differentiation (By similarity)

     Gene Ontology (GO): Selected molecular function terms (see all 6):    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0003690double-stranded DNA binding IBA--
GO:0003700sequence-specific DNA binding transcription factor activity ----
GO:0003705RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity IBA--
GO:0008134transcription factor binding IBA--
GO:0008301DNA binding, bending IBA--
     
Find genes that share ontologies with FOXQ1           About GenesLikeMe


Phenotypes:
     Selected MGI mutant phenotypes (inferred from 4 alleles(MGI details for Foxq1) (see all 18):
 behavior/neurological  cardiovascular system  craniofacial  digestive/alimentary  embryogenesis 
 growth/size/body  hearing/vestibular/ear  hematopoietic system  homeostasis/metabolism  immune system 
 integument  mortality/aging  nervous system  renal/urinary system  respiratory system 

Find genes that share phenotypes with FOXQ1           About GenesLikeMe

Animal Models:
     MGI mouse knock-out Foxq1tm1Wen for FOXQ1

   inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for FOXQ1
   inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for FOXQ1

   genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for FOXQ1
   genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for FOXQ1

Transcription Factor Targeting: 
Selected GeneGlobe predicted Target genes for FOXQ1 (see all 480):
ABCC10,  ACADSB,  ACOT2,  ACTR8,  ADAMTS19,  ADAT2,  ADRA1B,  AGAP10,  AGAP4,  AGAP5

miRNA
Products:
    
miRTarBase miRNAs that target FOXQ1:
hsa-mir-335-5p (MIRT018393), hsa-mir-24-3p (MIRT030583)

Block miRNA regulation of human, mouse, rat FOXQ1 using miScript Target Protectors
Selected qRT-PCR Assays for microRNAs that regulate FOXQ1 (see all 46):
hsa-miR-199a-3p hsa-miR-106a hsa-miR-128 hsa-miR-449a hsa-miR-342-3p hsa-miR-519a hsa-miR-9 hsa-miR-124
SwitchGear 3'UTR luciferase reporter plasmidFOXQ1 3' UTR sequence
Inhib. RNA
Products:
    
OriGene RNAi products in human, mouse, rat for FOXQ1
Predesigned siRNA for gene silencing in human, mouse, rat FOXQ1

Gene Editing
Products:
DNA2.0 Custom Protein Engineering Service for FOXQ1

Clone
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OriGene ORF clones in mouse, rat for FOXQ1
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GenScript: all cDNA clones in your preferred vector: FOXQ1 (NM_033260)
Browse Sino Biological Human cDNA Clones
DNA2.0 Custom Codon Optimized Gene Synthesis Service for FOXQ1
Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FOXQ1

Cell Line
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GenScript Custom overexpressing Cell Line Services for FOXQ1
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In Situ Assay
Products:
   

 
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FOXQ1


(According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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Subcellular locations from UniProtKB/Swiss-Prot
FOXQ1_HUMAN, Q9C009: Nucleus (By similarity)
Subcellular locations from COMPARTMENTS: 

CompartmentConfidence
nucleus3
cytosol2

Gene Ontology (GO): 2 cellular component terms:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0005634nucleus IEA--
GO:0005667transcription factor complex IBA--

Find genes that share ontologies with FOXQ1           About GenesLikeMe


(SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for FOXQ1
Interactions:

    Search GeneGlobe Interaction Network for FOXQ1

STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

4 Interacting proteins for FOXQ1 (Q9C0092, 3 ENSP000002968394) via UniProtKB, MINT, STRING, and/or I2D
InteractantInteraction Details
GeneCardExternal ID(s)
SSBP2P818773I2D: score=1 
SSBP3Q9BWW43I2D: score=1 
SRFENSP000002653544STRING: ENSP00000265354
--P310162MINT-8108504
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Gene Ontology (GO): Selected biological process terms (see all 8):    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0000122negative regulation of transcription from RNA polymerase II promoter IBA--
GO:0006355regulation of transcription, DNA-templated ----
GO:0006366transcription from RNA polymerase II promoter IBA--
GO:0007389pattern specification process IBA--
GO:0009790embryo development IBA--

Find genes that share ontologies with FOXQ1           About GenesLikeMe



(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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Browse Small Molecules at EMD Millipore
   Browse drugs & compounds from Enzo Life Sciences
  Browse compounds at ApexBio 

Browse Tocris compounds for FOXQ1



(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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REFSEQ mRNAs for FOXQ1 gene: 
NM_033260.3  

Unigene Cluster for FOXQ1:

Forkhead box Q1
Hs.591352  [show with all ESTs]
Unigene Representative Sequence: NM_033260
1 Ensembl transcript including schematic representation, and UCSC links where relevant:
ENST00000296839(uc003mtl.4)
miRNA
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Block miRNA regulation of human, mouse, rat FOXQ1 using miScript Target Protectors
Selected qRT-PCR Assays for microRNAs that regulate FOXQ1 (see all 46):
hsa-miR-199a-3p hsa-miR-106a hsa-miR-128 hsa-miR-449a hsa-miR-342-3p hsa-miR-519a hsa-miR-9 hsa-miR-124
SwitchGear 3'UTR luciferase reporter plasmidFOXQ1 3' UTR sequence
Inhib. RNA
Products:
     
OriGene RNAi products in human, mouse, rat for FOXQ1
Predesigned siRNA for gene silencing in human, mouse, rat FOXQ1
Clone
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OriGene clones in human, mouse for FOXQ1 (see all 6)
OriGene ORF clones in mouse, rat for FOXQ1
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
GenScript: all cDNA clones in your preferred vector: FOXQ1 (NM_033260)
DNA2.0 Custom Codon Optimized Gene Synthesis Service for FOXQ1
Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FOXQ1
Primer
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OriGene qPCR primer pairs and template standards for FOXQ1
OriGene qSTAR qPCR primer pairs in human, mouse for FOXQ1
Pre-validated RT2 qPCR Primer Assay in human, mouse, rat FOXQ1
  QuantiTect SYBR Green Assays in human, mouse, rat FOXQ1
  QuantiFast Probe-based Assays in human, mouse, rat FOXQ1

Additional mRNA sequence: BC053850.1 

3 DOTS entries:

DT.99999213  DT.426057  DT.99999388 

Selected AceView cDNA sequences (see all 47):

AI580870 AI682314 AA937534 AW628452 BM855255 BF592954 AW074092 AI671457 
BU685346 AI923975 AA551874 CB122633 BM782948 BM980542 NM_033260 AI926227 
AW291875 BU679521 BC053850 AI523736 BM982689 AI889694 BM508262 BM850814 

GeneLoc Exon Structure


(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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FOXQ1 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>2/3
CGAP TAG: TATAAATTTT
FOXQ1 Expression
About this image


FOXQ1 expression in embryonic tissues and stem cells    About this table
Data from LifeMap, the Embryonic Development and Stem Cells Database
 selected tissues (see all 9) fully expand
 
 Hair (Integumentary System)    fully expand to see all 3 entries
         Fetal Medulla Cells Hair Shaft
 
 Epithelial Cells
         Fetal Medulla Cells Hair Shaft
 
 Kidney (Urinary System)    fully expand to see all 2 entries
         Ureteric Bud Cells Ureteric Bud
 
 Neural Crest (Gastrulation Derivatives)
         PureStem 7PEND24, NCr-fac & Meso-prx Progenitor
 
 Gut Tube (Gastrointestinal Tract)
         Foregut
FOXQ1 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

FOXQ1 Protein Expression

SOURCE GeneReport for Unigene cluster: Hs.591352

UniProtKB/Swiss-Prot: FOXQ1_HUMAN, Q9C009
Tissue specificity: Expressed predominantly in the stomach, trachea, bladder and salivary gland

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In Situ
Assay Products:
 

 
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FOXQ1

(Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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This gene was present in the common ancestor of animals.

Orthologs for FOXQ1 gene from Selected species (see all 13)    About this table
Organism Taxonomic
classification
Gene Description Human
Similarity
Orthology
Type
Details
mouse
(Mus musculus)
Mammalia Foxq11 , 5 forkhead box Q11, 5 81.7(n)1
78.84(a)1
  13 (13.46 cM)5
152201  NM_008239.41  NP_032265.31 
 315583245 
chicken
(Gallus gallus)
Aves --
Uncharacterized protein
37(a)
many ↔ many
14(1799914-1802054)
tropical clawed frog
(Xenopus tropicalis)
Amphibia foxq11 forkhead box Q1 58.44(n)
54.81(a)
  733448  XM_002934401.2  XP_002934447.1 
zebrafish
(Danio rerio)
Actinopterygii foxq1b1 forkhead box Q1b 64.55(n)
73.17(a)
  405843  NM_212907.1  NP_998072.1 
fruit fly
(Drosophila melanogaster)
Insecta bin6
biniou
14(a)
1 ↔ 1
3L(6983722-6987544)
worm
(Caenorhabditis elegans)
Secernentea let-3816
Protein LET-381 (let-381) mRNA, complete cds
20(a)
1 ↔ 1
I(6320359-6323993) WBGene00002601


ENSEMBL Gene Tree for FOXQ1 (if available)
TreeFam Gene Tree for FOXQ1 (if available)

(Paralogs according to 1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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Paralogs for FOXQ1 gene
FOXF12  FOXN32  FOXJ12  FOXF22  FOXK12  FOXN42  FOXR12  FOXH12  
FOXK22  FOXN12  FOXJ32  FOXG12  FOXJ22  FOXN22  FOXR22  

Find genes that share paralogs with FOXQ1           About GenesLikeMe



(SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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Selected SNPs for FOXQ1 (see all 112)    About this table                                 

Genomic DataTranscription Related DataAllele Frequencies
SNP IDValidClinical
significance
Chr 6 posSequence#AA
Chg
TypeMore#Allele
freq
PopTotal
sample
More
----------
rs1882151111,2
--1310723(+) ATATAG/TATATA 1 -- us2k10--------
rs14372861,2
C,F,A--1310739(-) GGATGG/AGACAA 1 -- us2k110Minor allele frequency- A:0.42WA NA CSA EA 372
rs14372851,2
C,F--1310817(-) GGAGAC/TGAGCC 1 -- us2k111Minor allele frequency- T:0.42NA WA CSA EA 374
rs14372841,2
C,F,A--1310830(-) TGGCTG/TCTTTT 1 -- us2k17Minor allele frequency- T:0.37NA WA EA 366
rs95028881,2
C,F,A,H--1310839(+) CATTCC/TCCACC 1 -- us2k14Minor allele frequency- T:0.16NA CSA WA 242
rs1379717511,2
C--1310865(+) ATACT-/TAATAAAG 1 -- us2k10--------
rs1503071001,2
--1310948(+) TTGCCC/TGCCCC 1 -- us2k10--------
rs1144053071,2
C,F--1310984(+) GAATAA/GAGATA 1 -- us2k11Minor allele frequency- G:0.03NA 120
rs117552511,2
C,F,A,H--1311007(+) GTACGT/CTTTCA 1 -- us2k15Minor allele frequency- C:0.17NA CSA WA 244
rs1379280511,2
C--1311029(+) GGAAAA/GTAATA 1 -- us2k10--------

HapMap Linkage Disequilibrium report for FOXQ1 (1312675 - 1314993 bp)

Structural Variations
     Database of Genomic Variants (DGV) 2 variations for FOXQ1:    About this table    
Variant IDTypeSubtypePubMed ID
nsv883369CNV Gain21882294
nsv823393CNV Gain20364138

Site Specific Mutation Identification with PCR Assays
SeqTarget long-range PCR primers for resequencing FOXQ1
DNA2.0 Custom Variant and Variant Library Synthesis for FOXQ1

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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OMIM gene information: 612788    OMIM disorders: --

1 disease for FOXQ1:    
About MalaCards
duane retraction syndrome

1 disease from the University of Copenhagen DISEASES database for FOXQ1:
Duane retraction syndrome

Find genes that share disorders with FOXQ1           About GenesLikeMe

Genetic Association Database (GAD): FOXQ1

Export disorders for FOXQ1 gene to outside databases

(in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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PubMed articles for FOXQ1 gene, integrated from 10 sources (see all 23):
(articles sorted by number of sources associating them with FOXQ1)
    Utopia: connect your pdf to the dynamic
world of online information

  1. Isolation and characterization of the human forkhead gene FOXQ1. (PubMed id 11747606)1, 2, 3, 9 Bieller A....Zoll B. (DNA Cell Biol. 2001)
  2. Genome-wide association study of pancreatic cancer in Japanese population. (PubMed id 20686608)1, 4 Low S.K....Sakamoto H. (PLoS ONE 2010)
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
  4. Transforming growth factor-beta 2 is a transcriptional target for Akt/protein kinase B via forkhead transcription factor. (PubMed id 12011061)1, 3 Samatar A.A....Kumar C.C. (J. Biol. Chem. 2002)
  5. The winged helix/forkhead transcription factor Foxq1 regulates differentiation of hair in satin mice. (PubMed id 11309849)1, 2 Hong H.-K.... Chakravarti A. (Genesis 2001)
  6. FoxQ1 promotes glioma cells proliferation and migration by regulating NRXN3 expression. (PubMed id 23383267)1 Sun H.T....Zhang S. (PLoS ONE 2013)
  7. Large-scale genotyping identifies 41 new loci associated with breast cancer risk. (PubMed id 23535729)1 Michailidou K....Easton D.F. (Nat. Genet. 2013)
  8. Short hairpin RNA targeting FOXQ1 inhibits invasion and metastasis via the reversal of epithelial-mesenchymal transition in bladder cancer. (PubMed id 23403865)1 Zhu Z....Wang H. (Int. J. Oncol. 2013)
  9. FOXQ1, a novel target of the Wnt pathway and a new marker for activation of Wnt signaling in solid tumors. (PubMed id 23555880)1 Christensen J....Anderle P. (PLoS ONE 2013)
  10. Unraveling the role of FOXQ1 in colorectal cancer metastasis. (PubMed id 23723077)1 Abba M....Allgayer H. (Mol. Cancer Res. 2013)

(in PubMed, OMIM, and NCBI Bookshelf)
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 ANDOR
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(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 94234 HGNC: 20951 AceView: FOXQ1 Ensembl:ENSG00000164379 euGenes: HUgn94234
ECgene: FOXQ1 H-InvDB: FOXQ1

(According to HUGE)
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  --

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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NameDescription
PharmGKB entry for FOXQ1 Pharmacogenomics, SNPs, Pathways

(Patent information from GeneIP,
Licensable technologies from WIS Yeda, Salk, Tufts,
IP news from LifeMap Sciences, Inc.)
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Patent Information for FOXQ1 gene:
Search GeneIP for patents involving FOXQ1

GeneCards and IP:
Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
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