FOXO3B Gene
pseudogene GIFtS: 26
GCID: GC17M018565
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forkhead box O3B pseudogene(Previous name: forkhead (Drosophila) homolog (rhabdomyosarcoma) like 1...)
(Previous symbol: FKHRL1P1)
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Aliases
for FOXO3B gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
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This gene clusters with an RNA gene
Subcategory (RNA class): lncRNA
Quality score for the ORGUL clustered with this gene is 3
| Aliases |
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| Forkhead Box O3B Pseudogene1 2 | | FKHRL1P11 2 | | Forkhead (Drosophila) Homolog (Rhabdomyosarcoma) Like 1 Pseudogene 11 | | ZNF286C2 |
| External Ids: | HGNC: 38221 | Entrez Gene: 23102 | Ensembl: ENSG000002404457 | | ORGUL members: | |
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| NONCODE:n407257 | |
Export aliases for FOXO3B gene to outside databasesPrevious GC identifers: GC17U990029 GC17M018518 GC17M018776 GC17M018517
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Summaries
for FOXO3B gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
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Genomic Views
for FOXO3B gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000017.10 NC_018928.1 NT_010718.16
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the FOXO3B gene promoter:
GR p53 AP-1 Roaz HNF-4alpha1 NRF-2 POU2F1 POU2F1a SEF-1 (1) GR-alpha
Other transcription factors
Search SABiosciences Chromatin IP Primers for FOXO3B
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat FOXO3B |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 17p11.2 Ensembl cytogenetic band: 17p11.2 HGNC cytogenetic band: 17p11.2FOXO3B Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 17 GeneLoc Exon Structure GeneLoc location for GC17M018565: view genomic region
(about GC identifiers)
Start:
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18,569,236 bp from pter |
End:
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18,576,494 bp from pter |
Size:
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7,259 bases |
Orientation:
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minus strand |
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Proteins
for FOXO3B gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
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UniProtKB: --
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Protein
Domains /
Families
for FOXO3B gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
| -- |
Function
for FOXO3B gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
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Function Summary:
Genatlas biochemistry entry for FOXO3B:Drosophila forkhead gene homolog 1,like-sequence pseudogene 1
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FOXO3B |
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Pathways & Interactions
for FOXO3B gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
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Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for FOXO3B
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Drugs & Compounds
for FOXO3B gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for FOXO3B
Search CenterWatch for drugs/clinical trials and news about FOXO3B 
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Transcripts
for FOXO3B gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
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Unigene Cluster for FOXO3B: Forkhead box O3B pseudogene Hs.592126 [show with all ESTs]Unigene Representative Sequence: NR_0267181 Ensembl transcript including schematic representation, and UCSC links where relevant: ENST00000395675(uc010vye.1)
Additional cDNA sequence: AF041336.1 BC015367.1 NR_026718.1 9 DOTS entries: DT.100726911 DT.121004362 DT.121004366 DT.100649722 DT.100755530 DT.100702119 DT.100755532 DT.216108 DT.99940058 24/38 AceView cDNA sequences (see all 38): AW630403 Z42882 AF041336 CB138456 BE254284 BV184243 AV650110 BM686361 BV184242 AI355682 AW016415 BM797797 BG819228 BM827490 BQ278180 BE258317 BV200828 BE255538 AA569663 AA190390 CD611758 BU662809 Z39013 N46478
GeneLoc Exon Structure
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Expression
for FOXO3B gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| FOXO3B expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: --
About this image
Genevestigator expression for FOXO3B
SOURCE GeneReport for Unigene cluster: Hs.592126
SABiosciences Custom PCR Arrays for FOXO3B
Primer
Products: |  | Browse OriGene genome-wide validated SYBR primer pairs
Browse OriGene validated miRNA SYBR primer pairs
| | | Search SABiosciences RT2 qPCR
Primer Assays in human, mouse, rat FOXO3B | | | Search QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat FOXO3B | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat FOXO3B | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FOXO3B |
Orthologs
for FOXO3B gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
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ENSEMBL Gene Tree for FOXO3B (if available)
TreeFam Gene Tree for FOXO3B (if available) |
Paralogs
for FOXO3B gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
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Genomic Variants
for FOXO3B gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
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| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 17 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
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HapMap Linkage Disequilibrium report for FOXO3B (18569236 - 18576494 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 3 variations for FOXO3B
3 CNVs: 4993 30808 88369 | SABiosciences Cancer Mutation PCR Assays |
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Disorders
/ Diseases
for FOXO3B gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
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FOXO3B for disorders About GeneDecksing
1  disease for FOXO3B: About MalaCardsrhabdomyosarcoma
Export disorders for FOXO3B gene to outside databases
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Publications
for FOXO3B gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
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PubMed articles for FOXO3B gene integrated from 9 sources:
(articles sorted by number of sources associating them with FOXO3B) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Cloning and characterization of three human forkhead genes that comprise an FKHR-like gene subfamily. (PubMed id 9479491)1, 3 Anderson M.J.... Arden K.C. (1998)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
- Molecular cloning of FKHRL1P2, a member of the developmentally regulated fork head domain transcription factor family. (PubMed id 9852958)1 DaSilva L.... Farrar W.L. (1998)
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External Searches for FOXO3B gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
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Genome Databases showing FOXO3B gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
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Other Databases showing FOXO3B gene
(According to HUGE)
About This Section
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Specialized Databases showing FOXO3B gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
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About This Section
| Patent Information for FOXO3B gene:
Search GeneIP for patents involving FOXO3B
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Products
for FOXO3B gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
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|  | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat FOXO3B | | | Search QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing FOXO3B | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat FOXO3B | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat FOXO3B | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat FOXO3B | | | Search QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat FOXO3B |
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| | | | Search Tocris compounds for FOXO3B |
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 | | | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FOXO3B |
|  |  |  | | | | Search ThermoFisher Antibodies for FOXO3B |
| | | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat FOXO3B |
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Last full update: 18 Mar 2013 -
Incrementals: 21 Mar 2013 , 15 Apr 2013 , 27 Apr 2013
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