Aliases for FOXN3 Gene
External Ids for FOXN3 Gene
Previous HGNC Symbols for FOXN3 Gene
Previous GeneCards Identifiers for FOXN3 Gene
This gene is a member of the forkhead/winged helix transcription factor family. Checkpoints are eukaryotic DNA damage-inducible cell cycle arrests at G1 and G2. Checkpoint suppressor 1 suppresses multiple yeast checkpoint mutations including mec1, rad9, rad53 and dun1 by activating a MEC1-independent checkpoint pathway. Alternative splicing is observed at the locus, resulting in distinct isoforms. [provided by RefSeq, Jul 2008]
GeneCards Summary for FOXN3 Gene
FOXN3 (Forkhead Box N3) is a Protein Coding gene. Diseases associated with FOXN3 include Auditory Neuropathy. Among its related pathways are Mesodermal Commitment Pathway. GO annotations related to this gene include transcription factor activity, sequence-specific DNA binding and protein C-terminus binding. An important paralog of this gene is FOXN2.
UniProtKB/Swiss-Prot for FOXN3 Gene
Acts as a transcriptional repressor. May be involved in DNA damage-inducible cell cycle arrests (checkpoints).