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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

FOXN3 Gene

protein-coding   GIFtS: 50
GCID: GC14M089706

forkhead box N3

(Previous names: chromosome 14 open reading frame 116, checkpoint suppressor...)
(Previous symbols: C14orf116, CHES1)
 Explore 9 diseases affiliated with
FOXN3 via
MalaCards
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 Human Malady Compendium 
Biological research products
for FOXN3    

Aliases
for FOXN3 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
Forkhead Box N31 2     Chromosome 14 Open Reading Frame 1161
CHES11 2 3 5     PRO16352
Checkpoint Suppressor 11 2 3     Forkhead Box Protein N32
C14orf1161 2 3     

External Ids:    HGNC: 19281   Entrez Gene: 11122   Ensembl: ENSG000000532547   OMIM: 6026285   UniProtKB: O004093   

Export aliases for FOXN3 gene to outside databases

Previous GC identifers: GC14M088692 GC14M089622 GC14M069797


Summaries
for FOXN3 gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
Entrez Gene summary for FOXN3:
This gene is a member of the forkhead/winged helix transcription factor family. Checkpoints are eukaryotic DNA
damage-inducible cell cycle arrests at G1 and G2. Checkpoint suppressor 1 suppresses multiple yeast checkpoint
mutations including mec1, rad9, rad53 and dun1 by activating a MEC1-independent checkpoint pathway. Alternative
splicing is observed at the locus, resulting in distinct isoforms. (provided by RefSeq, Jul 2008)

UniProtKB/Swiss-Prot: FOXN3_HUMAN, O00409
Function: Acts as a transcriptional repressor. May be involved in DNA damage-inducible cell cycle arrests (checkpoints)

Gene Wiki entry for FOXN3


Genomic Views
for FOXN3 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000014.8  NC_018925.1  NT_026437.12  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the FOXN3 gene promoter:
         AP-2alpha isoform 3   Bach2   AP-2alpha isoform 2   C/EBPalpha   AREB6   FOXO4   AP-2alpha isoform 4   AP-2alpha   AP-2alphaA   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 4): FOXN3 promoter sequence
   Search SABiosciences Chromatin IP Primers for FOXN3

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat FOXN3


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 14q31.3   Ensembl cytogenetic band:  14q32.11   HGNC cytogenetic band: 14q32.11

FOXN3 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
FOXN3 gene location

GeneLoc information about chromosome 14         GeneLoc Exon Structure

GeneLoc location for GC14M089706:  view genomic region     (about GC identifiers)

Start:
 89,591,215 bp from pter      End:
 90,085,494 bp from pter
Size:
 494,280 bases      Orientation:
 minus strand

Proteins
for FOXN3 gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: FOXN3_HUMAN, O00409 (See protein sequence)
Recommended Name: Forkhead box protein N3  
Size: 490 amino acids; 53835 Da
Subunit: Interacts through its C-terminus with the C-terminus of SNW1/SKIP
Subcellular location: Nucleus (Probable)
Secondary accessions: Q96II7 Q9UIE7
Alternative splicing: 2 isoforms:  O00409-1   O00409-2   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for FOXN3: NX_O00409

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_O00409

    • FOXN3 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins (2 alternative transcripts): 
    NP_001078940.1  NP_005188.2  

    ENSEMBL proteins: 
     ENSP00000450783   ENSP00000343288   ENSP00000452005   ENSP00000452227   ENSP00000450833  
     ENSP00000451437   ENSP00000452444   ENSP00000450684   ENSP00000451024   ENSP00000451135  
     ENSP00000452290   ENSP00000451902   ENSP00000261302  

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    Browse ProSpec Recombinant Proteins
    Uscn Proteins for FOXN3

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IC16102918
    GO:0005667transcription factor complex IBA--


    FOXN3 for ontologies           About GeneDecksing



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    Protein Domains /
    Families
    for FOXN3 gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    FOXN3 for domains           About GeneDecksing

    3 InterPro domains/families:
     IPR011991 WHTH_trsnscrt_rep_DNA-bd_dom
     IPR018122 TF_fork_head_CS
     IPR001766 TF_fork_head

    Graphical View of Domain Structure for InterPro Entry O00409

    ProtoNet protein and cluster: O00409

    UniProtKB/Swiss-Prot: FOXN3_HUMAN, O00409
    Similarity: Contains 1 fork-head DNA-binding domain


    Function
    for FOXN3 gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    Function Summary:

         UniProtKB/Swiss-Prot: FOXN3_HUMAN, O00409
    Function: Acts as a transcriptional repressor. May be involved in DNA damage-inducible cell cycle arrests (checkpoints)

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    hsa-miR-640 hsa-miR-605 hsa-miR-128 hsa-miR-3653 hsa-miR-138-2* hsa-miR-759 hsa-miR-508-5p hsa-miR-3649
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    Clone
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    In Situ Assay
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    Gene Ontology (GO): 5/8 molecular function terms (GO ID links to tree view) (see all 8):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003690double-stranded DNA binding IBA--
    GO:0003700sequence-specific DNA binding transcription factor activity ----
    GO:0003705RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity IBA--
    GO:0005515protein binding IPI16102918
    GO:0008022protein C-terminus binding IPI16951149


    FOXN3 for ontologies           About GeneDecksing


    1 GenomeRNAi human phenotype for FOXN3:
     Increased gamma-H2AX phosphory 


    Pathways & Interactions
    for FOXN3 gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for FOXN3

    STRING Interaction Network Preview (showing 3 interactants - click image to see more details)

    5 Interacting proteins for FOXN3 (O004091, 3 ENSP000002613024) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    EXOSC8Q96B263, ENSP000003743544I2D: score=2 STRING: ENSP00000374354
    MEN1O002553, ENSP000003370884I2D: score=1 STRING: ENSP00000337088
    CDC23Q9UJX23I2D: score=1 
    SNW1Q135731EBI-372721,EBI-632715
    ELAVL1ENSP000003852694STRING: ENSP00000385269
    About this table

    Gene Ontology (GO): 5/8 biological process terms (GO ID links to tree view) (see all 8):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000077DNA damage checkpoint TAS9154802
    GO:0000085G2 phase of mitotic cell cycle TAS9154802
    GO:0006351transcription, DNA-dependent ----
    GO:0007389pattern specification process IBA--
    GO:0009790embryo development IBA--


    FOXN3 for ontologies           About GeneDecksing



    Drugs & Compounds
    for FOXN3 gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for FOXN3
    Search CenterWatch for drugs/clinical trials and news about FOXN3 

    Transcripts
    for FOXN3 gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for FOXN3 gene (2 alternative transcripts): 
    NM_001085471.1  NM_005197.3  

    Unigene Cluster for FOXN3:

    Forkhead box N3
    Hs.434286  [show with all ESTs]
    Unigene Representative Sequence: NM_005197
    18 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000557572 ENST00000345097(uc001xxn.4 uc001xxo.4 uc010atk.3)
    ENST00000557258 ENST00000555353 ENST00000553840 ENST00000556541 ENST00000555010
    ENST00000557496 ENST00000557718 ENST00000553353 ENST00000556916 ENST00000555658
    ENST00000554005 ENST00000557261 ENST00000555855(uc001xxp.2) ENST00000555034
    ENST00000553904 ENST00000261302

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    8/204 QIAGEN miScript miRNA Assays for microRNAs that regulate FOXN3 (see all 204):
    hsa-miR-640 hsa-miR-605 hsa-miR-128 hsa-miR-3653 hsa-miR-138-2* hsa-miR-759 hsa-miR-508-5p hsa-miR-3649
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
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    Additional cDNA sequence: 

    AF116643.2 AK055175.1 AK123929.1 AK225967.1 AK308053.1 AK314098.1 BC007506.2 BC010227.1 
    BC010460.1 U68723.1 

    23 DOTS entries:

    DT.95364202  DT.100780283  DT.99975505  DT.101960788  DT.120784181  DT.120784076  DT.92430326  DT.40121707 
    DT.121089966  DT.91702420  DT.120784334  DT.91702406  DT.100795350  DT.118147  DT.120784245  DT.92430313 
    DT.120783936  DT.121290117  DT.91702408  DT.95076327  DT.100780286  DT.120783971  DT.120784219 

    24/276 AceView cDNA sequences (see all 276):

    BU172864 AA777764 AI308995 BE676347 AI075957 NM_018589 BF002261 H23740 
    AA969536 BQ642883 AW057698 AA564019 BX283610 AA947170 AA827174 AI085236 
    AI078525 AW162250 BG506152 BQ027624 AI138825 AI652220 BQ065749 Z38395 

    GeneLoc Exon Structure

    4 Alternative Splicing Database (ASD) splice patterns (SP) for FOXN3    About this scheme

    ExUns: 1 ^ 2 ^ 3 ^ 4a · 4b ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10
    SP1:              -                 -           -     -               
    SP2:              -                 -           -                     
    SP3:                                                                  
    SP4:                                -                                 


    ECgene alternative splicing isoforms for FOXN3

    Expression
    for FOXN3 gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    FOXN3 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: TAAACCTAAA

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)
    About this image

    FOXN3 expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table
    1 LifeMap In Vivo Development Anatomical Compartment/Cell 
    Tissue Anatomical Compartment CellCategory (developmental path)
    EyeInner Nuclear LayerMature Rod Bipolar CellsBipolar, Retina
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization

    See FOXN3 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for FOXN3

    SOURCE GeneReport for Unigene cluster: Hs.434286
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    In Situ
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    Orthologs
    for FOXN3 gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of chordates.

    Orthologs for FOXN3 gene from 3/13 species (see all 13)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    chicken
    (Gallus gallus)    		 Aves FOXN31 forkhead box N3 83.26(n)
    88.84(a)    		   423402  XM_421312.3  XP_421312.2 
    lizard
    (Anolis carolinensis)    		 Reptilia FOXN36
    		 --
    		 88(a)
    		 1 ↔ 1
    		 1(13075381-13243860)
    zebrafish
    (Danio rerio)    		 Actinopterygii foxn31 forkhead box N3 77.69(n)
    83.87(a)    		   692291  NM_001045263.1  NP_001038728.1 


    ENSEMBL Gene Tree for FOXN3 (if available)
    TreeFam Gene Tree for FOXN3 (if available) 

    Paralogs
    for FOXN3 gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for FOXN3 gene
    FOXJ12  FOXK12  FOXN42  FOXN12  FOXK22  FOXP42  FOXG12  FOXJ32  
    FOXJ22  FOXP22  FOXN22  FOXP32  FOXP12  
    7 SIMAP similar genes for FOXN3 using alignment to 10 protein entries:     FOXN3_HUMAN (see all proteins):
    FOXC2    FOXJ3    FOXI1    FOXD1    FOXN2    FOXC1
    FOXK2

    FOXN3 for paralogs           About GeneDecksing


    1 Pseudogenes.org Pseudogene for FOXN3
    PGOHUM00000241477


    Genomic Variants
    for FOXN3 gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/8721 NCBI SNPs in FOXN3 are shown (see all 8721)     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 14 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs101424401,2
    		C,F,H,--69909315(+) gcaccT/Cacaca 1 -- ds500117Minor allele frequency- C:0.11NS EA NA CSA WA 1956
    rs101425321,2
    		C,F,A,H,--69909369(+) CTTGGT/CTTAGC 1 -- ds50019Minor allele frequency- C:0.07NS EA CSA WA NA 778
    rs80070231,2
    		C,F,H,--69909779(+) GAGAAT/CTGATG 1 -- nc-transcript-variant23Minor allele frequency- C:0.10NS EA NA WA CSA 2402
    rs790012191,2
    		F,--69910025(+) AGCTGG/ACACCT 1 -- nc-transcript-variant1Minor allele frequency- A:0.02WA 118
    rs792518341,2
    		--69910150(+) AAAAAG/TTGAAA 1 -- us2k11Minor allele frequency- T:0.01WA 118
    rs101332501,2
    		C,F,H,--69910161(+) ACTTCA/GTAACT 1 -- us2k118Minor allele frequency- G:0.11NS EA NA WA CSA 1970
    rs758588031,2
    		C,F,--69910298(+) TCACAA/GTATCC 1 -- us2k11Minor allele frequency- G:0.03NA 120
    rs769987791,2
    		F,--69910373(+) GCAGAC/TGTCAT 1 -- us2k11Minor allele frequency- T:0.08WA 118
    rs758225521,2
    		F,--69910955(+) CATTGG/AAGGGC 1 -- us2k11Minor allele frequency- A:0.02WA 118
    rs1117093721,2
    		C,--69911083(+) CCCCAC/TTGCCA 1 -- us2k11Minor allele frequency- T:0.50NA 2

    HapMap Linkage Disequilibrium report for FOXN3 (89591215 - 89841215 bp, first 250kb of FOXN3)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 11 variations for FOXN3
         2 CNVs: 87314 38314
         9 Indels: 87313 25450 11760 25451 25452 11761 40062 25449 71935

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    Disorders / Diseases
    for FOXN3 gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    FOXN3 for disorders           About GeneDecksing

    OMIM gene information: 602628    OMIM disorders: --

    9 diseases for FOXN3:    About MalaCards
    multiple endocrine neoplasia    auditory neuropathy    diabetes mellitus    laryngitis
    laryngeal carcinoma    neuropathy    hermaphroditism    hepatocellular carcinoma
    carcinoma

    2 Novoseek disease relationships for FOXN3 gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    tumors 11 1 16102918 (1)
    cancer 8.17 3 16102918 (2)

    Human Genome Epidemiology (HuGE) Navigator: FOXN3 (2 documents)

    Export disorders for FOXN3 gene to outside databases

    Publications
    for FOXN3 gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for FOXN3 gene, integrated from 9 sources (see all 26):
    (articles sorted by number of sources associating them with FOXN3)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. Reconstitution of a MEC1-independent checkpoint in yeast by expression of a novel human fork head cDNA. (PubMed id 9154802)1, 2, 3, 9 Pati D.... Plon S.E. (1997)
    2. CHES1/FOXN3 interacts with Ski-interacting protein and acts as a transcriptional repressor. (PubMed id 16102918)1, 2, 9 Scott K.L. and Plon S.E. (2005)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    4. The DNA sequence and analysis of human chromosome 14. (PubMed id 12508121)1, 2 Heilig R.... Weissenbach J. (2003)
    5. Multiple endocrine neoplasia type 1 interacts with forkhead transcription factor CHES1 in DNA damage response. (PubMed id 16951149)1, 9 Busygina V....Bale A.E. (2006)
    6. A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resi stance. (PubMed id 22581228)1 Manning A.K....Langenberg C. (2012)
    7. System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation. (PubMed id 21406692)2 Rigbolt K.T....Blagoev B. (2011)
    8. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1 Rose J.E....Uhl G.R. (2010)
    9. Maternal genes and facial clefts in offspring: a comp rehensive search for genetic associations in two population-based cleft studies from Scandinavia. (PubMed id 20634891)1 Jugessur A....Murray J.C. (2010)
    10. Foxn3 is essential for craniofacial development in mi ce and a putative candidate involved in human congenital craniofacial defects. (PubMed id 20691664)1 Samaan G....Venkatachalam S. (2010)

    External Searches for FOXN3 gene

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Disorders
    Free Text  
      Query String
    		PubMed
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    Genome Databases showing FOXN3 gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 1112 HGNC: 1928 AceView: CHES1 Ensembl:ENSG00000053254 euGenes: HUgn1112
    ECgene: FOXN3 H-InvDB: FOXN3

    Other Databases showing FOXN3 gene

    (According to HUGE)
    About This Section
    		   --

    Specialized Databases showing FOXN3 gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for FOXN3 Pharmacogenomics, SNPs, Pathways

    Intellectual Property
    for FOXN3 gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    		Patent Information for FOXN3 gene:
    Search GeneIP for patents involving FOXN3

    GeneCards and IP:
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