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Aliases for FOXJ3 Gene

Aliases for FOXJ3 Gene

  • Forkhead Box J3 2 3
  • KIAA1041 4

External Ids for FOXJ3 Gene

Previous GeneCards Identifiers for FOXJ3 Gene

  • GC01M042056
  • GC01M042311
  • GC01M042414
  • GC01M042642
  • GC01M040761

Summaries for FOXJ3 Gene

GeneCards Summary for FOXJ3 Gene

FOXJ3 (Forkhead Box J3) is a Protein Coding gene. GO annotations related to this gene include sequence-specific DNA binding transcription factor activity and DNA binding, bending. An important paralog of this gene is FOXK2.

UniProtKB/Swiss-Prot for FOXJ3 Gene

  • Transcriptional activator of MEF2C involved in the regulation pf adult muscle fiber type identity and skeletal muscle regeneration.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FOXJ3 Gene

Genomics for FOXJ3 Gene

Regulatory Elements for FOXJ3 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for FOXJ3 Gene

Start:
42,176,539 bp from pter
End:
42,335,877 bp from pter
Size:
159,339 bases
Orientation:
Minus strand

Genomic View for FOXJ3 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for FOXJ3 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for FOXJ3 Gene

Proteins for FOXJ3 Gene

  • Protein details for FOXJ3 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9UPW0-FOXJ3_HUMAN
    Recommended name:
    Forkhead box protein J3
    Protein Accession:
    Q9UPW0
    Secondary Accessions:
    • A7MBL7
    • A7MD18
    • D3DPW2
    • Q9NSS7

    Protein attributes for FOXJ3 Gene

    Size:
    622 amino acids
    Molecular mass:
    68960 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=BAA82993.2; Type=Erroneous initiation; Note=Translation N-terminally shortened.; Evidence={ECO:0000305};

    Alternative splice isoforms for FOXJ3 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for FOXJ3 Gene

Proteomics data for FOXJ3 Gene at MOPED

Post-translational modifications for FOXJ3 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for FOXJ3 Gene

Domains for FOXJ3 Gene

Gene Families for FOXJ3 Gene

HGNC:
  • FOX :Forkhead boxes

Protein Domains for FOXJ3 Gene

Suggested Antigen Peptide Sequences for FOXJ3 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q9UPW0

UniProtKB/Swiss-Prot:

FOXJ3_HUMAN :
  • Q9UPW0
Domain:
  • Contains 1 fork-head DNA-binding domain.
genes like me logo Genes that share domains with FOXJ3: view

Function for FOXJ3 Gene

Molecular function for FOXJ3 Gene

UniProtKB/Swiss-Prot Function: Transcriptional activator of MEF2C involved in the regulation pf adult muscle fiber type identity and skeletal muscle regeneration.

Gene Ontology (GO) - Molecular Function for FOXJ3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000981 sequence-specific DNA binding RNA polymerase II transcription factor activity IBA --
GO:0003700 sequence-specific DNA binding transcription factor activity --
GO:0043565 sequence-specific DNA binding IEA --
genes like me logo Genes that share ontologies with FOXJ3: view
genes like me logo Genes that share phenotypes with FOXJ3: view

Animal Model Products

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for FOXJ3

In Situ Assay Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targeting and HOMER Transcription for FOXJ3 Gene

Localization for FOXJ3 Gene

Subcellular locations from UniProtKB/Swiss-Prot for FOXJ3 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for FOXJ3 Gene COMPARTMENTS Subcellular localization image for FOXJ3 gene
Compartment Confidence
nucleus 3

Gene Ontology (GO) - Cellular Components for FOXJ3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IBA --
genes like me logo Genes that share ontologies with FOXJ3: view

Pathways for FOXJ3 Gene

SuperPathways for FOXJ3 Gene

No Data Available

Gene Ontology (GO) - Biological Process for FOXJ3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated --
GO:0006355 regulation of transcription, DNA-templated --
GO:0006357 regulation of transcription from RNA polymerase II promoter IBA --
GO:0006366 transcription from RNA polymerase II promoter IBA --
GO:0009653 anatomical structure morphogenesis IBA --
genes like me logo Genes that share ontologies with FOXJ3: view

No data available for Pathways by source for FOXJ3 Gene

Transcripts for FOXJ3 Gene

Unigene Clusters for FOXJ3 Gene

Forkhead box J3:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for FOXJ3

Primer Products

  • OriGene qSTAR qPCR primer pairs in human,mouse,rat for FOXJ3

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for FOXJ3 Gene

ExUns: 1 ^ 2 ^ 3 ^ 4a · 4b ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10a · 10b ^ 11 ^ 12 ^ 13a · 13b ^ 14a · 14b
SP1: - - -
SP2: - -
SP3:
SP4:

Relevant External Links for FOXJ3 Gene

GeneLoc Exon Structure for
FOXJ3
ECgene alternative splicing isoforms for
FOXJ3

Expression for FOXJ3 Gene

mRNA expression in normal human tissues for FOXJ3 Gene

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for FOXJ3 Gene

SOURCE GeneReport for Unigene cluster for FOXJ3 Gene Hs.26023

genes like me logo Genes that share expressions with FOXJ3: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for FOXJ3 Gene

Orthologs for FOXJ3 Gene

This gene was present in the common ancestor of chordates.

Orthologs for FOXJ3 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia FOXJ3 35
  • 99.68 (n)
  • 99.84 (a)
FOXJ3 36
  • 100 (a)
OneToOne
cow
(Bos Taurus)
Mammalia FOXJ3 35
  • 95.18 (n)
  • 97.43 (a)
FOXJ3 36
  • 97 (a)
OneToOne
dog
(Canis familiaris)
Mammalia FOXJ3 35
  • 95.23 (n)
  • 96.95 (a)
FOXJ3 36
  • 97 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Foxj3 35
  • 92.27 (n)
  • 94.69 (a)
Foxj3 16
Foxj3 36
  • 94 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia FOXJ3 36
  • 93 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 94 (a)
OneToMany
-- 36
  • 91 (a)
OneToMany
rat
(Rattus norvegicus)
Mammalia Foxj3 35
  • 91.84 (n)
  • 95.33 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia foxj3 35
  • 75.32 (n)
  • 77.22 (a)
zebrafish
(Danio rerio)
Actinopterygii foxj3 35
  • 71.35 (n)
  • 77.58 (a)
FOXJ3 36
  • 77 (a)
OneToOne
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 37 (a)
OneToOne
Species with no ortholog for FOXJ3:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for FOXJ3 Gene

ENSEMBL:
Gene Tree for FOXJ3 (if available)
TreeFam:
Gene Tree for FOXJ3 (if available)

Paralogs for FOXJ3 Gene

Selected SIMAP similar genes for FOXJ3 Gene using alignment to 5 proteins:

genes like me logo Genes that share paralogs with FOXJ3: view

Variants for FOXJ3 Gene

Sequence variations from dbSNP and Humsavar for FOXJ3 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type MAF
rs163850 -- 42,231,010(-) taagg(C/T)tgagt intron-variant
rs163851 -- 42,230,954(-) cttca(A/G)tgcac intron-variant
rs163852 -- 42,230,409(-) atctg(A/G)tatcc intron-variant
rs168229 -- 42,212,972(+) aaaaa(A/C)aaaaa intron-variant
rs168230 -- 42,215,897(-) taggt(A/G)tgtga intron-variant

Structural Variations from Database of Genomic Variants (DGV) for FOXJ3 Gene

Variant ID Type Subtype PubMed ID
nsv688 CNV Insertion 18451855
esv2663676 CNV Deletion 23128226
esv24371 CNV Loss 19812545
nsv871007 CNV Loss 21882294
esv22111 CNV Loss 19812545
esv2539470 CNV Deletion 19546169
esv2747530 CNV Deletion 23290073
esv270402 CNV Insertion 20981092
nsv870704 CNV Gain 21882294

Relevant External Links for FOXJ3 Gene

HapMap Linkage Disequilibrium report
FOXJ3

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for FOXJ3 Gene

Disorders for FOXJ3 Gene

Relevant External Links for FOXJ3

Genetic Association Database (GAD)
FOXJ3
Human Genome Epidemiology (HuGE) Navigator
FOXJ3
genes like me logo Genes that share disorders with FOXJ3: view

No data available for UniProtKB/Swiss-Prot for FOXJ3 Gene

Publications for FOXJ3 Gene

  1. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose J.E. … Uhl G.R. (Mol. Med. 2010) 3 48
  2. Prediction of the coding sequences of unidentified human genes. XIV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PMID: 10470851) Kikuno R. … Ohara O. (DNA Res. 1999) 3 4
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  4. A germline-specific class of small RNAs binds mammalian Piwi proteins. (PMID: 16751776) Girard A. … Carmell M.A. (Nature 2006) 3
  5. Ubiquitin-mediated proteolysis of HuR by heat shock. (PMID: 19322201) Abdelmohsen K. … Gorospe M. (EMBO J. 2009) 3

Products for FOXJ3 Gene

Sources for FOXJ3 Gene

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