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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

FOXI1 Gene

protein-coding   GIFtS: 50
GCID: GC05P169465

forkhead box I1


(Previous symbol: FKHL10)
 Explore 3 diseases affiliated with
FOXI1 via
MalaCards
our new
 Human Malady Compendium 
Biological research products
for FOXI1    

Aliases
for FOXI1 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
Forkhead Box I11 2     HNF-3/Fork-Head Homolog 32 3
FKHL101 2 3 5     FKH102
FREAC61 2 3 5     HFH32
Forkhead-Related Protein FKHL102 3     Forkhead Box Protein I12
Forkhead-Related Transcription Factor 62 3     Forkhead-Like 102
Hepatocyte Nuclear Factor 3 Forkhead Homolog 32 3     Forkhead-Related Activator 62
FREAC-62 3     HNF-3/Fork-Head Homolog-32
HFH-32 3     

External Ids:    HGNC: 38151   Entrez Gene: 22992   Ensembl: ENSG000001682697   OMIM: 6010935   UniProtKB: Q129513   

Export aliases for FOXI1 gene to outside databases

Previous GC identifers: GC05P169768 GC05P170236 GC05P169468 GC05P169513 GC05P164630


Summaries
for FOXI1 gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
Entrez Gene summary for FOXI1:
This gene belongs to the forkhead family of transcription factors which is characterized by a distinct forkhead domain.
The specific function of this gene has not yet been determined; however, it is possible that this gene plays an
important role in the development of the cochlea and vestibulum, as well as embryogenesis. Mutations in this gene may
be associated with the common cavity phenotype. Two transcript variants encoding different isoforms have been found
for this gene. (provided by RefSeq, Jul 2008)

UniProtKB/Swiss-Prot: FOXI1_HUMAN, Q12951
Function: Transcriptional activator required for the development of normal hearing, sense of balance and kidney
function. Required for the expression of SLC26A4/PDS, JAG1 and COCH in a subset of epithelial cells and the
development of the endolymphatic system in the inner ear. Also required for the expression of SLC4A1/AE1, SLC4A9/AE4,
ATP6V1B1 and the differentiation of intercalated cells in the epithelium of distal renal tubules (By similarity)

Gene Wiki entry for FOXI1


Genomic Views
for FOXI1 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000005.9  NC_018916.1  NT_023133.13  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the FOXI1 gene promoter:
         CREB   PPAR-gamma1   Sp1   deltaCREB   PPAR-gamma2   NRSF form 2   Zic3   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: FOXI1 promoter sequence
   Search SABiosciences Chromatin IP Primers for FOXI1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat FOXI1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 5q34   Ensembl cytogenetic band:  5q35.1   HGNC cytogenetic band: 5q34

FOXI1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
FOXI1 gene location

GeneLoc information about chromosome 5         GeneLoc Exon Structure

GeneLoc location for GC05P169465:  view genomic region     (about GC identifiers)

Start:
 169,532,901 bp from pter      End:
 169,536,729 bp from pter
Size:
 3,829 bases      Orientation:
 plus strand

Proteins
for FOXI1 gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: FOXI1_HUMAN, Q12951 (See protein sequence)
Recommended Name: Forkhead box protein I1  
Size: 378 amino acids; 40973 Da
Subcellular location: Nucleus
Sequence caution: Sequence=AAB50574.1; Type=Erroneous initiation; Sequence=AAU12169.1; Type=Erroneous initiation;
Secondary accessions: Q14518 Q66SR7 Q8N6L8
Alternative splicing: 2 isoforms:  Q12951-1   Q12951-2   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for FOXI1: NX_Q12951

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q12951

    • FOXI1 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins (2 alternative transcripts): 
    NP_036320.2  NP_658982.1  

    ENSEMBL proteins: 
     ENSP00000304286   ENSP00000415483  

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    Novus Biologicals FOXI1 Protein
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    Uscn Proteins for FOXI1

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IC19214237
    GO:0005667transcription factor complex IBA--


    FOXI1 for ontologies           About GeneDecksing



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    Protein Domains /
    Families
    for FOXI1 gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    FOXI1 for domains           About GeneDecksing

    3 InterPro domains/families:
     IPR011991 WHTH_trsnscrt_rep_DNA-bd_dom
     IPR018122 TF_fork_head_CS
     IPR001766 TF_fork_head

    Graphical View of Domain Structure for InterPro Entry Q12951

    ProtoNet protein and cluster: Q12951

    UniProtKB/Swiss-Prot: FOXI1_HUMAN, Q12951
    Similarity: Contains 1 fork-head DNA-binding domain


    Function
    for FOXI1 gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    Function Summary:

         UniProtKB/Swiss-Prot: FOXI1_HUMAN, Q12951
    Function: Transcriptional activator required for the development of normal hearing, sense of balance and kidney
    function. Required for the expression of SLC26A4/PDS, JAG1 and COCH in a subset of epithelial cells and the
    development of the endolymphatic system in the inner ear. Also required for the expression of SLC4A1/AE1, SLC4A9/AE4,
    ATP6V1B1 and the differentiation of intercalated cells in the epithelium of distal renal tubules (By similarity)

         Genatlas biochemistry entry for FOXI1:
    transcription factor-like 10,with a Drosophila homeo forkhead DNA binding domain homolog

    10/522 SABiosciences Target genes for FOXI1 (see all 522):
    AADACL4 AASDH ABCA8 ABCC2 ABHD8 ABRA ABTB2 ACAD10 ACP6 ACSS3

    miRNA
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    SwitchGear 3'UTR luciferase reporter plasmid: FOXI1 3' UTR sequence
    Inhib. RNA
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    Gene Editing
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    Clone
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    Cell Line
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    Search LifeMap BioReagents cell lines for FOXI1

    In Situ Assay
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    Gene Ontology (GO): 5/7 molecular function terms (GO ID links to tree view) (see all 7):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003690double-stranded DNA binding IBA--
    GO:0003700sequence-specific DNA binding transcription factor activity IDA19214237
    GO:0003705RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity IBA--
    GO:0008134transcription factor binding IBA--
    GO:0008301DNA binding, bending NAS7957066


    FOXI1 for ontologies           About GeneDecksing


    Animal Models:
         Mouse knock-out Foxi1tm1Sven for FOXI1
         10 MGI mutant phenotypes (inferred from 1 allele) (MGI details for Foxi1):
     behavior/neurological  cellular  craniofacial  hearing/vestibular/ear  homeostasis/metabolism 
     mortality/aging  nervous system  renal/urinary system  reproductive system  skeleton 

    FOXI1 for phenotypes           About GeneDecksing


    Pathways & Interactions
    for FOXI1 gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for FOXI1

    Gene Ontology (GO): 5/8 biological process terms (GO ID links to tree view) (see all 8):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007389pattern specification process IBA--
    GO:0009790embryo development NAS7957066
    GO:0009957epidermal cell fate specification IBA--
    GO:0042472inner ear morphogenesis ----
    GO:0043049otic placode formation IBA--


    FOXI1 for ontologies           About GeneDecksing



    Drugs & Compounds
    for FOXI1 gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for FOXI1
    Search CenterWatch for drugs/clinical trials and news about FOXI1 

    Transcripts
    for FOXI1 gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for FOXI1 gene (2 alternative transcripts): 
    NM_012188.4  NM_144769.2  

    Unigene Cluster for FOXI1:

    Forkhead box I1
    Hs.87236  [show with all ESTs]
    Unigene Representative Sequence: NM_012188
    2 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000306268 ENST00000449804(uc003mai.4 uc003maj.4)

    miRNA
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    hsa-miR-4330 hsa-miR-432 hsa-miR-4267
    SwitchGear 3'UTR luciferase reporter plasmid: FOXI1 3' UTR sequence
    Inhib. RNA
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    Additional cDNA sequence: 

    AK292176.1 AY707089.1 BC029778.1 L13203.1 

    2 DOTS entries:

    DT.100742346  DT.40124462 

    13 AceView cDNA sequences:

    NM_012188 BX279766 NM_144769 CA489445 BM982734 AA741219 BC029778 AI302387 
    CA489033 AY707089 L13203 BI761811 BG271646 

    GeneLoc Exon Structure


    Expression
    for FOXI1 gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    FOXI1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: GACCAGTGAG

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)
    About this image

    FOXI1 expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table
    5 LifeMap In Vivo Development Anatomical Compartments/Cells 
    Tissue Anatomical Compartment CellCategory (developmental path)
    KidneyRenal Collecting Duct SystemIntercalated CellsKidney
    KidneyRenal Collecting Duct SystemCollecting Duct CellsKidney
    KidneyDistal TubuleDistal Tubule CellsKidney
    KidneyDistal TubuleKidney
    KidneyRenal Collecting Duct SystemKidney
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization
    Stem Cell Differentiation: 1 LifeMap Cell 
    NameCategory
    Definitive endoderm-like cells (A scalable, suspensi...)

    See FOXI1 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for FOXI1

    SOURCE GeneReport for Unigene cluster: Hs.87236

    UniProtKB/Swiss-Prot: FOXI1_HUMAN, Q12951
    Tissue specificity: Expressed in kidney

        SABiosciences Expression via Pathway-Focused PCR Arrays including FOXI1: 
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              Molecular Toxicology PathwayFinder 384HT in human mouse rat
              Cell Death PathwayFinder in human mouse rat

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    In Situ
    Assay Products:     
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    Orthologs
    for FOXI1 gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of animals.

    Orthologs for FOXI1 gene from 6/15 species (see all 15)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    mouse
    (Mus musculus)    		 Mammalia Foxi11 , 5 forkhead box I11, 5 84.01(n)1
    85.44(a)1    		   11 (19.65 cM)5
    142331  NM_023907.41  NP_076396.31 
     342043385 
    chicken
    (Gallus gallus)    		 Aves FOXI11 forkhead box I1 69.16(n)
    71.2(a)    		   427613  XM_425185.3  XP_425185.1 
    lizard
    (Anolis carolinensis)    		 Reptilia FOXI16
    		 --
    		 71(a)
    		 1 ↔ 1
    		 2(120523068-120525295)
    African clawed frog
    (Xenopus laevis)    		 Amphibia foxi1-prov2 forkhead box I1 75.75(n)    BC042303.1 
    zebrafish
    (Danio rerio)    		 Actinopterygii foxi3b2 forkhead box I3b 71.71(n)   387258  AY331584.1 
    worm
    (Caenorhabditis elegans)    		 Secernentea fkh-66
    		 ForKHead transcription factor family member (fkh-6...
    		 21(a)
    		 1 → many
    		 II(4379886-4383290)


    ENSEMBL Gene Tree for FOXI1 (if available)
    TreeFam Gene Tree for FOXI1 (if available) 

    Paralogs
    for FOXI1 gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for FOXI1 gene
    FOXF12  FOXA22  FOXD4L12  FOXF22  FOXC22  FOXB12  FOXI22  FOXE32  
    FOXC12  FOXD4L22  FOXQ12  FOXD4L32  FOXA32  FOXD12  FOXD32  FOXD4L52  
    FOXD4L42  FOXE12  FOXL12  FOXA12  FOXB22  FOXD4L62  FOXS12  FOXD22  
    FOXL22  FOXD42  
    8 SIMAP similar genes for FOXI1 using alignment to 3 protein entries:     FOXI1_HUMAN (see all proteins):
    FOXJ3    FOXN3    FOXI2    FOXL2    FOXI3    FOXC1
    FOXS1    FOXB1

    FOXI1 for paralogs           About GeneDecksing


    1 Pseudogenes.org Pseudogene for FOXI1
    PGOHUM00000240140


    Genomic Variants
    for FOXI1 gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/135 NCBI SNPs in FOXI1 are shown (see all 135)     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 5 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs1219093411,2
    		Cpathogenic176291322(+) GAAGCG/AGCCCT 3 /Q /R int1 mis11Minor allele frequency- A:0.00EU 1071
    rs1219093401,2
    		C,Fpathogenic176291349(+) ACCAGG/AGGGCA 3 /E /G mis1 int11Minor allele frequency- A:0.00NA 4540
    rs1137148701,2
    		C,--164628952(+) GTGTGC/TCTTAC 2 -- us2k12Minor allele frequency- T:0.04CSA WA 120
    rs119596211,2
    		C,F,H,,--164629914(+) gtgcgC/Tgtgtg 2 -- us2k13Minor allele frequency- T:0.50NA WA CSA 6
    rs561282171,2
    		C,--164631635(+) TCCTTC/TCTCCC 2 -- int11Minor allele frequency- T:0.50NA 2
    rs563558251,2
    		C,--164631683(+) CCCCCA/CAAGAC 2 -- int10--------
    rs77039501,2
    		C,--164632319(+) GAGAGA/GCATGT 2 -- int10--------
    rs775996201,2
    		F,--164633002(+) TTCCTG/ACATCT 2 -- int11Minor allele frequency- A:0.02WA 118
    rs771365371,2
    		F,--164633042(+) AGGAGG/AAACAG 2 -- int11Minor allele frequency- A:0.03EA 120
    rs1113106171,2
    		C,F--164633429(+) GTCACA/GCCAGG 4 T syn12Minor allele frequency- G:0.00CSA NA 4554

    HapMap Linkage Disequilibrium report for FOXI1 (169532901 - 169536729 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
          Database of Genomic Variants (DGV) variations for FOXI1: --
    Human Gene Mutation Database (HGMD): FOXI1

    SABiosciences Cancer Mutation PCR Assays
    QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing FOXI1
    DNA2.0 Custom Variant and Variant Library Synthesis for FOXI1

    Disorders / Diseases
    for FOXI1 gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    FOXI1 for disorders           About GeneDecksing

    OMIM gene information: 601093   
    OMIM disorders: 600791  
    3 diseases for FOXI1:    About MalaCards
    enlarged vestibular aqueduct    renal tubular acidosis    lymphedema

    3 diseases from the University of Copenhagen DISEASES database for FOXI1:
    Enlarged vestibular aqueduct     Renal tubular acidosis     Nonsyndromic deafness
    Human Genome Epidemiology (HuGE) Navigator: FOXI1 (4 documents)

    Export disorders for FOXI1 gene to outside databases

    Publications
    for FOXI1 gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for FOXI1 gene, integrated from 9 sources (see all 19):
    (articles sorted by number of sources associating them with FOXI1)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. Cloning and characterization of seven human forkhead proteins: binding site specificity and DNA bending. (PubMed id 7957066)1, 2, 3 Pierrou S....Carlsson P. (1994)
    2. The winged helix transcriptional activator HFH-3 is expressed in the distal tubules of embryonic and adult mouse kidney. (PubMed id 9153225)1, 2, 9 Overdier D.G.... Costa R.H. (1997)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    4. Chromosomal localization of six human forkhead genes, freac-1 (FKHL5), -3 (FKHL7), -4 (FKHL8), -5 (FKHL9), -6 (FKHL10), and -8 (FKHL12). (PubMed id 8825632)1, 3 Larsson C....Carlsson P. (1995)
    5. Screening of SLC26A4, FOXI1, KCNJ10, and GJB2 in bilat eral deafness patients with inner ear malformation. (PubMed id 22412181)1 Chen K....Jiang H. (2012)
    6. Interactions of pathological hallmark proteins: tubul in polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. (PubMed id 21832049)1 OlA!h J....OvA!di J. (2011)
    7. Screening of SLC26A4, FOXI1 and KCNJ10 genes in unila teral hearing impairment with ipsilateral enlarged vestibular aqueduct. (PubMed id 20621367)1 Jonard L....Marlin S. (2010)
    8. African signatures of recent positive selection in human FOXI1. (PubMed id 20809947)1 Moreno-Estrada A.... Bosch E. (2010)
    9. Dynamics of cullin-RING ubiquitin ligase network revea led by systematic quantitative proteomics. (PubMed id 21145461)1 Bennett E.J....Harper J.W. (2010)
    10. The forkhead transcription factor Foxi1 is a master regulator of vacuolar H-ATPase proton pump subunits in the inner ear, kidney and epididymis. (PubMed id 19214237)1 Vidarsson H....EnerbAock S. (2009)

    External Searches for FOXI1 gene

    (in PubMed, OMIM, and NCBI Bookshelf)
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    Genome Databases showing FOXI1 gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 2299 HGNC: 3815 AceView: FOXI1 Ensembl:ENSG00000168269 euGenes: HUgn2299
    ECgene: FOXI1 H-InvDB: FOXI1

    Other Databases showing FOXI1 gene

    (According to HUGE)
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    Specialized Databases showing FOXI1 gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for FOXI1 Pharmacogenomics, SNPs, Pathways

    Intellectual Property
    for FOXI1 gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    		Patent Information for FOXI1 gene:
    Search GeneIP for patents involving FOXI1

    GeneCards and IP:
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