Aliases for FOXD1 Gene
External Ids for FOXD1 Gene
Previous HGNC Symbols for FOXD1 Gene
Previous GeneCards Identifiers for FOXD1 Gene
This gene belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. Studies of the orthologous mouse protein indicate that it functions in kidney development by promoting nephron progenitor differentiation, and it also functions in the development of the retina and optic chiasm. It may also regulate inflammatory reactions and prevent autoimmunity. [provided by RefSeq, Apr 2014]
GeneCards Summary for FOXD1 Gene
FOXD1 (Forkhead Box D1) is a Protein Coding gene. Diseases associated with FOXD1 include Croup and Townes-Brocks Syndrome. GO annotations related to this gene include transcription factor activity, sequence-specific DNA binding and RNA polymerase II core promoter proximal region sequence-specific DNA binding. An important paralog of this gene is FOXD2.
UniProtKB/Swiss-Prot for FOXD1 Gene
Transcription factor required for formation of positional identity in the developing retina, regionalization of the optic chiasm and morphogenesis of the kidney. Can neuralize ectodermal cells directly (By similarity).