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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

FOXD1 Gene

protein-coding   GIFtS: 47
GCID: GC05M072743

forkhead box D1


(Previous symbol: FKHL8)
 Explore 1 disease affiliated with
FOXD1 via
MalaCards
our new
 Human Malady Compendium 
Biological research products
for FOXD1    

Aliases
for FOXD1 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
Forkhead Box D11 2     FREAC-42 3
FKHL81 2 3 5     Forkhead Box Protein D12
FREAC41 2 3     Forkhead, Drosophila, Homolog-Like 82
Forkhead-Related Protein FKHL82 3     Forkhead-Like 82
Forkhead-Related Transcription Factor 42 3     Forkhead-Related Activator 42

External Ids:    HGNC: 38021   Entrez Gene: 22972   Ensembl: ENSG000002514937   OMIM: 6010915   UniProtKB: Q166763   

Export aliases for FOXD1 gene to outside databases

Previous GC identifers: GC05M071547 GC05M072975 GC05M072780 GC05M072826 GC05M072777 GC05M067947


Summaries
for FOXD1 gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
Entrez Gene summary for FOXD1:
This intronless gene belongs to the forkhead family of transcription factors which is characterized by a distinct
forkhead domain. The specific function of this gene has not yet been determined; however, it may play a role in tumor
formation. (provided by RefSeq, Jul 2008)

UniProtKB/Swiss-Prot: FOXD1_HUMAN, Q16676
Function: Transcription factor required for formation of positional identity in the developing retina, regionalization
of the optic chiasm and morphogenesis of the kidney. Can neuralize ectodermal cells directly (By similarity)




Genomic Views
for FOXD1 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000005.9  NC_018916.1  NT_006713.15  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the FOXD1 gene promoter:
         Egr-3   Nkx2-5   FOXO4   FOXJ2 (long isoform)   FOXO1a   FOXJ2   FOXO1   ATF   
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search SABiosciences Chromatin IP Primers for FOXD1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat FOXD1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 5q12-q13   Ensembl cytogenetic band:  5q13.2   HGNC cytogenetic band: 5q12-q13

FOXD1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
FOXD1 gene location

GeneLoc information about chromosome 5         GeneLoc Exon Structure

GeneLoc location for GC05M072743:  view genomic region     (about GC identifiers)

Start:
 72,740,654 bp from pter      End:
 72,744,352 bp from pter
Size:
 3,699 bases      Orientation:
 minus strand

Proteins
for FOXD1 gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: FOXD1_HUMAN, Q16676 (See protein sequence)
Recommended Name: Forkhead box protein D1  
Size: 465 amino acids; 46140 Da
Subcellular location: Nucleus
Secondary accessions: Q12949

Explore the universe of human proteins at neXtProt for FOXD1: NX_Q16676

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q16676

    • FOXD1 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins: NP_004463.1  
    ENSEMBL proteins: 
     ENSP00000462795  

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    Uscn Proteins for FOXD1

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IC7957066
    GO:0005667transcription factor complex IBA--


    FOXD1 for ontologies           About GeneDecksing



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    Protein Domains /
    Families
    for FOXD1 gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    FOXD1 for domains           About GeneDecksing

    3 InterPro domains/families:
     IPR011991 WHTH_trsnscrt_rep_DNA-bd_dom
     IPR018122 TF_fork_head_CS
     IPR001766 TF_fork_head

    Graphical View of Domain Structure for InterPro Entry Q16676

    ProtoNet protein and cluster: Q16676

    UniProtKB/Swiss-Prot: FOXD1_HUMAN, Q16676
    Similarity: Contains 1 fork-head DNA-binding domain


    Function
    for FOXD1 gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    Function Summary:

         UniProtKB/Swiss-Prot: FOXD1_HUMAN, Q16676
    Function: Transcription factor required for formation of positional identity in the developing retina, regionalization
    of the optic chiasm and morphogenesis of the kidney. Can neuralize ectodermal cells directly (By similarity)

         Genatlas biochemistry entry for FOXD1:
    transcription factor-like 8,with a Drosophila homeo forkhead DNA binding domain homolog,kidney expressed (involved in
    kidney development)

    10/379 SABiosciences Target genes for FOXD1 (see all 379):
    AADACL2 ABCA6 ABT1 ACOT2 ACOT9 ACSBG1 ACTR1A ADAMTS14 AGXT2 AKAP14

    miRNA
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    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat FOXD1
    8/21 QIAGEN miScript miRNA Assays for microRNAs that regulate FOXD1 (see all 21):
    hsa-miR-30c hsa-miR-4251 hsa-miR-548k hsa-miR-30d hsa-miR-216b hsa-miR-3133 hsa-miR-30a hsa-miR-186
    SwitchGear 3'UTR luciferase reporter plasmid: FOXD1 3' UTR sequence
    Inhib. RNA
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    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for FOXD1 (see all 4)
    OriGene shRNA RFP: FOXD1
    OriGene siRNA: FOXD1
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat FOXD1

    Gene Editing
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    Clone
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    Cell Line
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    LifeMap BioReagents: cell lines associated with FOXD1: PureStem 7SMOO32, NCr-fac & Meso Progenitor,
    PureStem MEL2, NCr-fac Progenitor

    In Situ Assay
    Products:       
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    Gene Ontology (GO): 5/7 molecular function terms (GO ID links to tree view) (see all 7):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003677DNA binding IDA7957066
    GO:0003690double-stranded DNA binding IBA--
    GO:0003700sequence-specific DNA binding transcription factor activity TAS8702877
    GO:0003705RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity IBA--
    GO:0008134transcription factor binding IBA--


    FOXD1 for ontologies           About GeneDecksing


    1 GenomeRNAi human phenotype for FOXD1:
     Decreased Hepatitis C virus re 

    Animal Models:
         10 MGI mutant phenotypes (inferred from 3 alleles) (MGI details for Foxd1):
     behavior/neurological  digestive/alimentary  endocrine/exocrine gland  growth/size  mortality/aging 
     nervous system  no phenotypic analysis  renal/urinary system  respiratory system  vision/eye 

    FOXD1 for phenotypes           About GeneDecksing


    Pathways & Interactions
    for FOXD1 gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for FOXD1

    Gene Ontology (GO): 5/26 biological process terms (GO ID links to tree view) (see all 26):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0001658branching involved in ureteric bud morphogenesis ----
    GO:0001755neural crest cell migration IBA--
    GO:0001822kidney development ----
    GO:0007389pattern specification process IBA--
    GO:0007411axon guidance ----


    FOXD1 for ontologies           About GeneDecksing



    Drugs & Compounds
    for FOXD1 gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for FOXD1
    Search CenterWatch for drugs/clinical trials and news about FOXD1 

    Transcripts
    for FOXD1 gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for FOXD1 gene: 
    NM_004472.2  

    Unigene Cluster for FOXD1:

    Forkhead box D1
    Hs.519385  [show with all ESTs]
    Unigene Representative Sequence: NM_004472
    2 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000513595 ENST00000499003

    miRNA
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    8/21 QIAGEN miScript miRNA Assays for microRNAs that regulate FOXD1 (see all 21):
    hsa-miR-30c hsa-miR-4251 hsa-miR-548k hsa-miR-30d hsa-miR-216b hsa-miR-3133 hsa-miR-30a hsa-miR-186
    SwitchGear 3'UTR luciferase reporter plasmid: FOXD1 3' UTR sequence
    Inhib. RNA
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    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for FOXD1 (see all 4)
    OriGene shRNA RFP: FOXD1
    OriGene siRNA: FOXD1
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    Clone
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    Primer
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    Additional cDNA sequence: 

    U13222.1 U59832.1 

    2 DOTS entries:

    DT.113053  DT.95264588 

    24/25 AceView cDNA sequences (see all 25):

    BU728193 BM929966 AA885070 U13222 BU621287 AA341525 AA724254 CB112634 
    AW022278 AI739311 BV204581 U59832 BM999901 AA778677 CB149239 BG121021 
    BM706862 AI073371 AI818164 AA977269 NM_004472 AI823914 W46229 BI495774 

    GeneLoc Exon Structure


    Expression
    for FOXD1 gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    FOXD1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: TTTACACAAG

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)
    About this image

    FOXD1 expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table
    10/15 LifeMap In Vivo Development Anatomical Compartments/Cells (see all 15) 
    Tissue Anatomical Compartment CellCategory (developmental path)
    KidneyInterstitial StromaInterstitial Stroma CellsKidney
    Head MesenchymeBranchial Arch 1Cranial Neural Crest CellsNeural Crest
    Head MesenchymePrechordal MesenchymeDiencephalic Neural Crest CellsNeural Crest
    Head MesenchymePrechordal MesenchymeMesencephalic Neural Crest CellsNeural Crest
    KidneyPodocyte LayerPodocytesKidney
    KidneyPodocyte LayerPresumptive PodocytesKidney
    BrainBlood Brain BarrierPostnatal Endothelial CellsBlood Brain Barrier, Endothelium
    KidneyMetanephric MesenchymeMetanephric Mesenchyme CellsKidney
    SomiteThoracic Ventrolateral Dermomyotome LipMuscle Progenitor CellsSkeletal Muscle
    BoneMandibular ProcessBone
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization
    Stem Cell Differentiation: 9 LifeMap Cells 
    NameCategory
    PureStem™ mesenchymal progenitor MEL2 (Embryonic Progenitor Cell)Adipose, Bone, Cartilage
    PureStem™ mesenchymal progenitor 7SMOO32 (Embryonic Progenitor Cell)Adipose, Bone, Cartilage
    mK3 (Cell line)Kidney
    mK4 (Cell line)Kidney
    PureStem™ mesenchymal Progenitor SK11 (Embryonic Progenitor Cell)Adipose, Bone, Cartilage
    PureStem™ mesenchymal progenitor SM30 (Embryonic Progenitor Cell)Adipose, Bone, Cartilage
    PureStem™ progenitor EN7 (Embryonic Progenitor Cell)
    PureStem™ progenitor W10 (Embryonic Progenitor Cell)
    Intermediate mesoderm derivatives (Generation of interm...)

    See FOXD1 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for FOXD1

    SOURCE GeneReport for Unigene cluster: Hs.519385
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    In Situ
    Assay Products:     
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    Orthologs
    for FOXD1 gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of eukaryotes.

    Orthologs for FOXD1 gene from 7/18 species (see all 18)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    chicken
    (Gallus gallus)    		 Aves FOXD11 forkhead box D1 77.81(n)
    75(a)    		   396109  NM_205192.1  NP_990523.1 
    lizard
    (Anolis carolinensis)    		 Reptilia --
    		 --
    		 33(a)
    		 1 ↔ 1
    		 2(15952341-15953942)
    African clawed frog
    (Xenopus laevis)    		 Amphibia foxd1-A2 forkhead box D1 80.17(n)    AJ011652.1 
    zebrafish
    (Danio rerio)    		 Actinopterygii foxd1l1 forkhead box D1 like 64.71(n)
    65.15(a)    		   405849  NM_212913.1  NP_998078.1 
    fruit fly
    (Drosophila melanogaster)    		 Insecta fd59A3 embryonic morphogenesis transcription factor 83(a)   59B4   --
    worm
    (Caenorhabditis elegans)    		 Secernentea unc-1303 fork head domain protein 77(a)   II(11281899-11283574)   --
    rice
    (Oryza sativa)    		 Liliopsida Os.182572 Oryza sativa (japonica cultivar-group) cDNA cloneJ more 71.23(n)    AK120944.1 


    ENSEMBL Gene Tree for FOXD1 (if available)
    TreeFam Gene Tree for FOXD1 (if available) 

    Paralogs
    for FOXD1 gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for FOXD1 gene
    FOXF12  FOXA22  FOXD4L12  FOXF22  FOXC22  FOXB12  FOXI22  FOXE32  
    FOXC12  FOXD4L22  FOXQ12  FOXD4L32  FOXA32  FOXD32  FOXD4L52  FOXD4L42  
    FOXE12  FOXL12  FOXA12  FOXB22  FOXI12  FOXD4L62  FOXS12  FOXL22  
    FOXD22  FOXD42  
    18/22 SIMAP similar genes for FOXD1 using alignment to 2 protein entries:     FOXD1_HUMAN (see all proteins) (see all similar genes):
    FOXJ3    FOXN3    FOXA3    FOXC1    FOXB1    FOXI2
    FOXL1    FOXD4L6    FOXD2    FOXD4L3    FOXD4L5    FOXD4L2
    FOXD4L4    FOXL2    FOXS1    FOXD4L1    FOXE3    FOXF1

    FOXD1 for paralogs           About GeneDecksing



    Genomic Variants
    for FOXD1 gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/45 NCBI SNPs in FOXD1 are shown (see all 45)     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 5 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs1824404971,2
    		--72741684(+) TTATGC/TTGACA 1 -- ds50010--------
    rs730977481,2
    		C,--72741712(+) ATTGTC/TGTGAA 1 -- ds50012Minor allele frequency- T:0.07WA 120
    rs1176653861,2
    		C,F,--72741954(+) ATGGCA/GTGATG 1 -- ds50011Minor allele frequency- G:0.03EA 120
    rs9619351,2
    		C,F,A,--72741965(+) CTGTTG/CTTAAA 1 -- ds500113Minor allele frequency- C:0.46NA EA WA CSA 623
    rs1875802161,2
    		--72742215(+) AAGTAC/TAAAAA 1 -- ut310--------
    rs1143441991,2
    		--72742336(+) CAGACA/TAGTGT 1 -- ut311Minor allele frequency- T:0.01WA 118
    rs1932562351,2
    		--72742451(+) TACACC/GTCAAA 1 -- ut310--------
    rs1457137801,2
    		--72742485(+) CCAAAC/GGTCAA 1 -- ut310--------
    rs737620891,2
    		C,--72742621(+) CCAAAA/CGGCGC 1 -- ut312Minor allele frequency- C:0.41WA 120
    rs1836742751,2
    		--72742780(+) GCGCTA/CACATA 1 -- ut310--------

    HapMap Linkage Disequilibrium report for FOXD1 (72740654 - 72744352 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 2 variations for FOXD1
         2 CNVs: 64230 80956

    SABiosciences Cancer Mutation PCR Assays
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    DNA2.0 Custom Variant and Variant Library Synthesis for FOXD1

    Disorders / Diseases
    for FOXD1 gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    FOXD1 for disorders           About GeneDecksing

    OMIM gene information: 601091    OMIM disorders: --

    1 disease for FOXD1:    About MalaCards
    wilms tumor


    Export disorders for FOXD1 gene to outside databases

    Publications
    for FOXD1 gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for FOXD1 gene integrated from 9 sources:
    (articles sorted by number of sources associating them with FOXD1)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. Cloning and characterization of seven human forkhead proteins: binding site specificity and DNA bending. (PubMed id 7957066)1, 2, 3 Pierrou S....Carlsson P. (1994)
    2. Characterization of the human forkhead gene FREAC-4. Evidence for regulation by Wilms' tumor suppressor gene (WT-1) and p53. (PubMed id 8702877)1, 2 Ernstsson S.... Enerbaeck S. (1996)
    3. Chromosomal localization of six human forkhead genes, freac-1 (FKHL5), -3 (FKHL7), -4 (FKHL8), -5 (FKHL9), -6 (FKHL10), and -8 (FKHL12). (PubMed id 8825632)1, 3 Larsson C....Carlsson P. (1995)
    4. Smad6s regulates plasminogen activator inhibitor-1 through a protein kinase C-beta-dependent up-regulation of transforming growth factor-beta. (PubMed id 15716278)1, 9 Berg D.T....Grinnell B.W. (2005)

    External Searches for FOXD1 gene

    (in PubMed, OMIM, and NCBI Bookshelf)
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    Genome Databases showing FOXD1 gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 2297 HGNC: 3802 AceView: FOXD1 Ensembl:ENSG00000251493 euGenes: HUgn2297
    ECgene: FOXD1 H-InvDB: FOXD1

    Other Databases showing FOXD1 gene

    (According to HUGE)
    About This Section
    		   --

    Specialized Databases showing FOXD1 gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for FOXD1 Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for FOXD1 Genetics and Cytogenetics in Oncology and Haematology

    Intellectual Property
    for FOXD1 gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    		Patent Information for FOXD1 gene:
    Search GeneIP for patents involving FOXD1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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