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FOXB1 Gene

protein-coding   GIFtS: 47
GCID: GC15P060296

Forkhead Box B1

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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This gene clusters with an RNA gene
Subcategory (RNA class): lncRNA

Quality score for the ORGUL clustered with this gene is 3

Aliases
Forkhead Box B11 2
Transcription Factor FKH-52 3
FKH52 3
HFKH-52
Forkhead Box Protein B12

External Ids:    HGNC: 37991   Entrez Gene: 270232   Ensembl: ENSG000001719567   UniProtKB: Q998533   
ORGUL members:         

Export aliases for FOXB1 gene to outside databases

Previous GC identifers: GC15P055855 GC15P053345 GC15P057876 GC15P058013 GC15P058084 GC15P037118


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for FOXB1 Gene:
FOXB1 (forkhead box B1) is a protein-coding gene. Diseases associated with FOXB1 include wernicke-korsakoff syndrome, and atherosclerosis. GO annotations related to this gene include double-stranded DNA binding and sequence-specific DNA binding. An important paralog of this gene is FOXA2.


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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Regulatory elements:
   Regulatory transcription factor binding sites in the FOXB1 gene promoter:
         E2F-4   E2F-3a   E2F-5   E2F-2   Max   S8   POU2F1   E2F-1   E2F   HFH-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidFOXB1 promoter sequence
   Search Chromatin IP Primers for FOXB1

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat FOXB1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 15q22   Ensembl cytogenetic band:  15q22.2   HGNC cytogenetic band: 15q22

FOXB1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
FOXB1 gene location

GeneLoc information about chromosome 15         GeneLoc Exon Structure

GeneLoc location for GC15P060296:  view genomic region     (about GC identifiers)

Start:
60,296,421 bp from pter      End:
60,353,929 bp from pter
Size:
57,509 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
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UniProtKB/Swiss-Prot: FOXB1_HUMAN, Q99853 (See protein sequence)
Recommended Name: Forkhead box protein B1  
Size: 325 amino acids; 34978 Da
Secondary accessions: O60652 O75917 Q14CL2

Explore the universe of human proteins at neXtProt for FOXB1: NX_Q99853

Explore proteomics data for FOXB1 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See FOXB1 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_036314.2  
    ENSEMBL proteins: 
     ENSP00000379369  

    FOXB1 Human Recombinant Protein Products:

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    Novus Biologicals FOXB1 Lysate
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    Cloud-Clone Corp. Proteins for FOXB1

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    Abcam antibodies for FOXB1 (Q99853, Q5VYV0)
    Cloud-Clone Corp. Antibodies for FOXB1
    ThermoFisher Antibodies for FOXB1
    LSBio Antibodies in human, mouse, rat for FOXB1

    FOXB1 Assay Products:

    Browse Kits and Assays available from EMD Millipore
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    GenScript Custom Assay Services for FOXB1
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for FOXB1
    Cloud-Clone Corp. CLIAs for FOXB1


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    FOX: Forkhead boxes

    3 InterPro protein domains:
     IPR011991 WHTH_DNA-bd_dom
     IPR018122 TF_fork_head_CS
     IPR001766 TF_fork_head

    Graphical View of Domain Structure for InterPro Entry Q99853

    ProtoNet protein and cluster: Q99853

    UniProtKB/Swiss-Prot: FOXB1_HUMAN, Q99853
    Similarity: Contains 1 fork-head DNA-binding domain


    FOXB1 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:
         Genatlas biochemistry entry for FOXB1:
    transcription factor-like 5,with a Drosophila homeo forkhead DNA binding domain homolog

         Gene Ontology (GO): Selected molecular function terms (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003690double-stranded DNA binding IBA--
    GO:0003700sequence-specific DNA binding transcription factor activity ----
    GO:0003705RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity IBA--
    GO:0008134transcription factor binding IBA--
    GO:0008301DNA binding, bending IBA--
         
    FOXB1 for ontologies           About GeneDecksing


    Phenotypes:
         2 GenomeRNAi human phenotypes for FOXB1:
     Decreased BPV1 E2 protein expr  Increased HPV18 LCR reporter a 

         9 MGI mutant phenotypes (inferred from 6 alleles(MGI details for Foxb1):
     behavior/neurological  embryogenesis  endocrine/exocrine gland  growth/size/body  integument 
     mortality/aging  nervous system  no phenotypic analysis  other 

    FOXB1 for phenotypes           About GeneDecksing

    Animal Models:
         MGI mouse knock-outs for FOXB1: Foxb1tm1Blh Foxb1tm1Pgr

       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for FOXB1
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for FOXB1

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for FOXB1
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for FOXB1

    miRNA
    Products:
        
    Block miRNA regulation of human, mouse, rat FOXB1 using miScript Target Protectors
    Search for qRT-PCR Assays for microRNAs that regulate FOXB1
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for FOXB1
    Predesigned siRNA for gene silencing in human, mouse, rat FOXB1

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for FOXB1

    Clone
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    OriGene clones in human, mouse for FOXB1 (see all 5)
    OriGene ORF clones in mouse, rat for FOXB1
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: FOXB1 (NM_012182)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for FOXB1
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FOXB1

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for FOXB1
    Browse ESI BIO Cell Lines and PureStem Progenitors for FOXB1 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FOXB1


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    FOXB1_HUMAN, Q99853: Nucleus (By similarity)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus3

    Gene Ontology (GO): 2 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus ISS--
    GO:0005667transcription factor complex IBA--

    FOXB1 for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for FOXB1
    Interactions:

        Search GeneGlobe Interaction Network for FOXB1

    STRING Interaction Network Preview (showing 3 interactants - click image to see more details)

    3 Interacting proteins for FOXB1 (Q998533 ENSP000003793694) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    TCEB3Q142413, ENSP000003955744I2D: score=1 STRING: ENSP00000395574
    COPB1ENSP000002499234STRING: ENSP00000249923
    PHF5AENSP000002162524STRING: ENSP00000216252
    About this table

    Gene Ontology (GO): Selected biological process terms (see all 26):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000122negative regulation of transcription from RNA polymerase II promoter IBA--
    GO:0001655urogenital system development IEA--
    GO:0001756somitogenesis ISS--
    GO:0006355regulation of transcription, DNA-templated ----
    GO:0006366transcription from RNA polymerase II promoter IBA--

    FOXB1 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for FOXB1



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for FOXB1 gene: 
    NM_012182.2  

    3 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000396057(uc002agj.1) ENST00000560857(uc010bgh.1) ENST00000558693

    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat FOXB1 using miScript Target Protectors
    Search for qRT-PCR Assays for microRNAs that regulate FOXB1
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for FOXB1
    Predesigned siRNA for gene silencing in human, mouse, rat FOXB1
    Clone
    Products:
         
    OriGene clones in human, mouse for FOXB1 (see all 5)
    OriGene ORF clones in mouse, rat for FOXB1
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: FOXB1 (NM_012182)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for FOXB1
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FOXB1
    Primer
    Products:
        
    OriGene qSTAR qPCR primer pairs in human, mouse for FOXB1
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat FOXB1
      QuantiTect SYBR Green Assays in human, mouse, rat FOXB1
      QuantiFast Probe-based Assays in human, mouse, rat FOXB1

    3 AceView cDNA sequences:

    NM_012182 AF071554 U87393 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    FOXB1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GCGAGTGGCG
    FOXB1 Expression
    About this image


    FOXB1 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 4) fully expand
     
     Neural Tube (Nervous System)    fully expand to see all 4 entries
             Metencephalon
     
     Brain (Nervous System)    fully expand to see all 2 entries
             Medulla Oblongata
     
     Epiblast (Early Embryonic Tissues)
             Epiblast Stem Cell line 7
     
     Spinal Cord (Nervous System)
    FOXB1 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    FOXB1 Protein Expression
        Custom PCR Arrays for FOXB1
    Primer
    Products:
    OriGene qSTAR qPCR primer pairs in human, mouse for FOXB1
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat FOXB1
    QuantiTect SYBR Green Assays in human, mouse, rat FOXB1
    QuantiFast Probe-based Assays in human, mouse, rat FOXB1
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FOXB1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for FOXB1 gene from Selected species (see all 13)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Foxb11 , 5 forkhead box B11, 5 92(n)1
    99.69(a)1
      9 (38.76 cM)5
    642901  NM_022378.31  NP_071773.21 
     697577105 
    chicken
    (Gallus gallus)
    Aves FOXB11 forkhead box B1 89.58(n)
    94.37(a)
      100859030  XM_004943754.1  XP_004943811.1 
    African clawed frog
    (Xenopus laevis)
    Amphibia fkh-52 forkhead-domain-containing protein 5 77.45(n)    AF064810.1 
    zebrafish
    (Danio rerio)
    Actinopterygii foxb1.22 forkhead box B1.2 79.45(n)   30542  AF052246.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta fd96Ca3 embryonic morphogenesis transcription
    factor
    84(a)
    (best of 3)
      96B20   --
    worm
    (Caenorhabditis elegans)
    Secernentea lin-313 Expression: VPC, L1 larva, L2 larva, L3
    larva
    77(a)   II(3982653-3986466)   --


    ENSEMBL Gene Tree for FOXB1 (if available)
    TreeFam Gene Tree for FOXB1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for FOXB1 gene
    FOXA22  FOXD4L12  FOXC22  FOXI22  FOXE32  FOXC12  FOXD4L22  FOXD4L32  
    FOXA32  FOXD4L52  FOXD12  FOXD32  FOXD4L42  FOXA12  FOXE12  FOXL12  
    FOXB22  FOXI12  FOXD4L62  FOXS12  FOXD22  FOXL22  FOXD42  
    11 SIMAP similar genes for FOXB1 using alignment to 1 protein entry:     FOXB1_HUMAN:
    FOXA3    FOXC1    FOXL1    FOXA2    FOXI2    FOXI3
    FOXD1    FOXB2    FOXS1    FOXF1    FOXI1

    FOXB1 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for FOXB1 (see all 85)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 15 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1440262801,2
    C--60294434(+) CCAAAA/CGCCGC 1 -- us2k10--------
    rs1464465891,2
    --60294554(+) AATACA/GTTTAT 1 -- us2k10--------
    rs1906654601,2
    --60294630(+) CTCCTC/TCTCCC 1 -- us2k10--------
    rs1837155671,2
    --60294708(+) AACGTA/GCGCTT 1 -- us2k10--------
    rs1869949241,2
    --60294801(+) GTTACG/TTTTTG 1 -- us2k10--------
    rs1493630971,2
    C--60294847(+) GAAGT-/TGTGTGT 1 -- us2k10--------
    rs1409479591,2
    --60294892(+) GAAAGA/TTCTTT 1 -- us2k10--------
    rs1923856891,2
    --60294995(+) TCTAGG/TGAAAA 1 -- us2k10--------
    rs727399421,2
    C,F--60295171(+) CAGGCG/AGGGTC 1 -- us2k11Minor allele frequency- A:0.03NA 120
    rs1825134411,2
    --60295200(+) TAGCAA/GTTTGA 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for FOXB1 (60296421 - 60353929 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 4 variations for FOXB1:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv1554CNV Loss18451855
    nsv833028CNV Gain17160897
    nsv904280CNV Gain21882294
    nsv7266OTHER Inversion18451855

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing FOXB1
    DNA2.0 Custom Variant and Variant Library Synthesis for FOXB1

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    3 diseases for FOXB1:    
    About MalaCards
    wernicke-korsakoff syndrome    atherosclerosis    neuronitis

    1 disease from the University of Copenhagen DISEASES database for FOXB1:
    Wernicke-Korsakoff syndrome

    FOXB1 for disorders           About GeneDecksing

    Genetic Association Database (GAD): FOXB1

    Export disorders for FOXB1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for FOXB1 gene integrated from 10 sources:
    (articles sorted by number of sources associating them with FOXB1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Toward an understanding of the protein interaction network of the human liver. (PubMed id 21988832)1 Wang J....Yang X. (Mol. Syst. Biol. 2011)
    2. A genome-wide association study for blood lipid phenotypes in the Framingham Heart Study. (PubMed id 17903299)4 Kathiresan S....Cupples L.A. (BMC Med. Genet. 2007)
    3. Genome-wide association study for subclinical atherosclerosis in major arterial territories in the NHLBI's Framingham Heart Study. (PubMed id 17903303)4 O'Donnell C.J....Demissie S. (BMC Med. Genet. 2007)
    4. A genome-wide association for kidney function and endocrine-related traits in the NHLBI's Framingham Heart Study. (PubMed id 17903292)4 Hwang S.J....Fox C.S. (BMC Med. Genet. 2007)
    5. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (Genome Res. 2006)
    6. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    7. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)2 Ota T.... Sugano S. (Nat. Genet. 2004)
    8. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)
    9. (PubMed id )2 

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 27023 HGNC: 3799 AceView: FOXB1 Ensembl:ENSG00000171956 euGenes: HUgn27023
    ECgene: FOXB1 H-InvDB: FOXB1

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for FOXB1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for FOXB1 gene:
    Search GeneIP for patents involving FOXB1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, and ESI BIO, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
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