External Ids for FOSL1 Gene
Previous GeneCards Identifiers for FOSL1 Gene
The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014]
GeneCards Summary for FOSL1 Gene
FOSL1 (FOS-Like Antigen 1) is a Protein Coding gene. Diseases associated with FOSL1 include pfeiffer syndrome. Among its related pathways are Apoptotic Pathways in Synovial Fibroblasts and Akt Signaling. GO annotations related to this gene include transcription factor activity, sequence-specific DNA binding and RNA polymerase II regulatory region sequence-specific DNA binding. An important paralog of this gene is FOSL2.